DVL2 (dishevelled segment polarity protein 2) - Rat Genome Database
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Gene: DVL2 (dishevelled segment polarity protein 2) Pan paniscus
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Symbol: DVL2
Name: dishevelled segment polarity protein 2
RGD ID: 12004841
Description: ENCODES a protein that exhibits frizzled binding (ortholog); identical protein binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN canonical Wnt signaling pathway (ortholog); canonical Wnt signaling pathway involved in regulation of cell proliferation (ortholog); cellular protein localization (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; Wnt signaling, non-canonical pathway; ASSOCIATED WITH dyskeratosis congenita (ortholog); Weissenbacher-Zweymuller syndrome (ortholog); FOUND IN aggresome (ortholog); apical part of cell (ortholog); clathrin-coated vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: dishevelled, dsh homolog 2; segment polarity protein dishevelled homolog DVL-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1177,242,493 - 7,251,572 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,242,493 - 7,251,571 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0177,255,241 - 7,264,452 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
DVL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1177,242,493 - 7,251,572 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,242,493 - 7,251,571 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0177,255,241 - 7,264,452 (-)NCBIMhudiblu_PPA_v0panPan3
DVL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl177,225,342 - 7,234,517 (-)EnsemblGRCh38hg38GRCh38
GRCh38177,225,341 - 7,234,544 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37177,128,661 - 7,137,836 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,069,385 - 7,078,587 (-)NCBINCBI36hg18NCBI36
Build 34177,069,384 - 7,078,587NCBI
Celera177,153,295 - 7,162,512 (-)NCBI
Cytogenetic Map17p13.1NCBI
HuRef177,020,651 - 7,029,658 (-)NCBIHuRef
CHM1_1177,137,409 - 7,146,611 (-)NCBICHM1_1
Dvl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,891,418 - 69,900,935 (+)NCBIGRCm39mm39
GRCm39 Ensembl1169,891,421 - 69,903,127 (+)Ensembl
GRCm381170,000,592 - 70,010,109 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,000,595 - 70,012,301 (+)EnsemblGRCm38mm10GRCm38
MGSCv371169,814,128 - 69,823,611 (+)NCBIGRCm37mm9NCBIm37
MGSCv361169,816,821 - 69,826,304 (+)NCBImm8
Celera1177,548,436 - 77,558,061 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.96NCBI
Dvl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21054,723,356 - 54,732,823 (+)NCBI
Rnor_6.0 Ensembl1056,610,051 - 56,619,269 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01056,609,810 - 56,619,269 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01056,354,931 - 56,364,388 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1053,877,195 - 53,886,407 (+)NCBICelera
Cytogenetic Map10q24NCBI
Dvl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554679,675,912 - 9,683,996 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554679,675,912 - 9,683,996 (+)NCBIChiLan1.0ChiLan1.0
DVL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl532,194,313 - 32,201,857 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1532,194,326 - 32,201,922 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dvl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936595520,299 - 528,361 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DVL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,579,765 - 52,590,292 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,581,687 - 52,590,266 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23139,857,220 - 139,865,809 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DVL2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1166,599,056 - 6,608,613 (-)NCBI
ChlSab1.1 Ensembl166,599,579 - 6,608,544 (-)Ensembl
Dvl2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247869,843,580 - 9,851,538 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000038911   ⟹   ENSPPAP00000016217
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl177,242,493 - 7,251,571 (-)Ensembl
RefSeq Acc Id: XM_003810108   ⟹   XP_003810156
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1177,242,493 - 7,251,572 (-)NCBI
Mhudiblu_PPA_v0177,255,241 - 7,264,452 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008962468   ⟹   XP_008960716
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1177,242,493 - 7,251,572 (-)NCBI
Mhudiblu_PPA_v0177,255,619 - 7,264,438 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003810156 (Get FASTA)   NCBI Sequence Viewer  
  XP_008960716 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_008960716   ⟸   XM_008962468
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_003810156   ⟸   XM_003810108
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSPPAP00000016217   ⟸   ENSPPAT00000038911
Protein Domains
DEP   DIX   PDZ


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031206 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000016217 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000038911 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  2.30.42.10 UniProtKB/TrEMBL
  3.10.20.380 UniProtKB/TrEMBL
InterPro DEP_dom UniProtKB/TrEMBL
  Dishevelled_C-dom UniProtKB/TrEMBL
  Dishevelled_fam UniProtKB/TrEMBL
  Dishevelled_protein_dom UniProtKB/TrEMBL
  DIX UniProtKB/TrEMBL
  DIX_dom_sf UniProtKB/TrEMBL
  Dsh/Dvl-rel UniProtKB/TrEMBL
  DVL2 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene DVL2 ENTREZGENE
PANTHER PTHR10878 UniProtKB/TrEMBL
  PTHR10878:SF8 UniProtKB/TrEMBL
Pfam DEP UniProtKB/TrEMBL
  Dishevelled UniProtKB/TrEMBL
  DIX UniProtKB/TrEMBL
  Dsh_C UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
PRINTS DISHEVELLED UniProtKB/TrEMBL
  DISHEVELLED2 UniProtKB/TrEMBL
PROSITE DEP UniProtKB/TrEMBL
  DIX UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
SMART DAX UniProtKB/TrEMBL
  DEP UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
  SSF50156 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
UniProt A0A2R9AFV8_PANPA UniProtKB/TrEMBL