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ONTOLOGY REPORT - ANNOTATIONS

Term:intestinal epithelial cell differentiation
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Accession:GO:0060575 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine.


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intestinal epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBFA2T2 CBFA2/RUNX1 partner transcriptional co-repressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:33,490,096...33,650,030
Ensembl chr20:33,490,075...33,650,036 		JBrowse link
G CDX2 caudal type homeobox 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr13:27,960,918...27,969,315
Ensembl chr13:27,960,918...27,969,315 		JBrowse link
G GATA4 GATA binding protein 4 acts_upstream_of_or_within IDA (PMID:9566909) MGI PMID:9566909 NCBI chr 8:11,676,935...11,760,002
Ensembl chr 8:11,676,959...11,760,002 		JBrowse link
G GATA5 GATA binding protein 5 acts_upstream_of_or_within IDA (PMID:9566909) MGI PMID:9566909 NCBI chr20:62,463,497...62,475,995
Ensembl chr20:62,463,497...62,475,995 		JBrowse link
G GATA6 GATA binding protein 6 acts_upstream_of_or_within IDA (PMID:9566909) MGI PMID:9566909 NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528 		JBrowse link
G NPY neuropeptide Y involved_in TAS (PMID:10488139) GO_Central PMID:10488139 NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862 		JBrowse link
G PTK6 protein tyrosine kinase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:63,528,001...63,537,376
Ensembl chr20:63,528,001...63,537,376 		JBrowse link
G PYY peptide YY involved_in TAS (PMID:10488139) GO_Central PMID:10488139 NCBI chr17:43,952,733...44,004,445
Ensembl chr17:43,952,733...44,004,469 		JBrowse link
G SAV1 salvador family WW domain containing protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18369314) Ensembl
MGI		 PMID:18369314 GO_REF:0000107 NCBI chr14:50,633,580...50,668,306
Ensembl chr14:50,632,058...50,668,306 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17681175) Ensembl
MGI		 PMID:17681175 GO_REF:0000107 NCBI chr17:72,121,020...72,126,416
Ensembl chr17:72,121,020...72,126,416 		JBrowse link
G YAP1 Yes1 associated transcriptional regulator involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17980593) Ensembl
MGI		 PMID:17980593 GO_REF:0000107 NCBI chr11:102,110,447...102,233,424
Ensembl chr11:102,110,447...102,233,424 		JBrowse link
enterocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G YAP1 Yes1 associated transcriptional regulator involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17980593) Ensembl
MGI		 PMID:17980593 GO_REF:0000107 NCBI chr11:102,110,447...102,233,424
Ensembl chr11:102,110,447...102,233,424 		JBrowse link
intestinal epithelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21383503) Ensembl
MGI		 PMID:21383503 GO_REF:0000107 NCBI chr 7:7,157,377...7,248,616
Ensembl chr 7:7,156,934...7,248,616 		JBrowse link
G CDH1 cadherin 1 acts_upstream_of_or_within ISO (PMID:22766025) MGI PMID:22766025 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G DICER1 dicer 1, ribonuclease III acts_upstream_of_or_within ISO (PMID:21307095) MGI PMID:21307095 NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010 		JBrowse link
G GSDMC gasdermin C involved_in ISO (PMID:17350798) UniProt PMID:17350798 NCBI chr 8:129,705,435...129,786,624
Ensembl chr 8:129,748,196...129,786,624 		JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer involved_in IDA
IEA		 (PMID:25731159) UniProt
Ensembl		 PMID:25731159 GO_REF:0000107 NCBI chr 5:55,935,095...55,994,963
Ensembl chr 5:55,935,095...55,995,022 		JBrowse link
G KLF5 KLF transcription factor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23266329) Ensembl
MGI		 PMID:23266329 GO_REF:0000107 NCBI chr13:73,054,976...73,077,538
Ensembl chr13:73,054,976...73,077,541 		JBrowse link
G MIR203B microRNA 203b acts_upstream_of_or_within ISO (PMID:21307095) MGI PMID:21307095 NCBI chr14:104,117,418...104,117,503
Ensembl chr14:104,117,418...104,117,503 		JBrowse link
G MIR7-1 microRNA 7-1 acts_upstream_of_or_within ISO (PMID:21307095) MGI PMID:21307095 NCBI chr 9:83,969,748...83,969,857
Ensembl chr 9:83,969,748...83,969,857 		JBrowse link
G NKX3-2 NK3 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21307095) Ensembl
MGI		 PMID:21307095 GO_REF:0000107 NCBI chr 4:13,540,830...13,547,744
Ensembl chr 4:13,540,830...13,544,508 		JBrowse link
G PRDM1 PR/SET domain 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21670299) Ensembl
MGI		 PMID:21670299 GO_REF:0000107 NCBI chr 6:105,992,690...106,109,938
Ensembl chr 6:105,993,463...106,109,939 		JBrowse link
G SPDEF SAM pointed domain containing ETS transcription factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19549527) Ensembl
MGI		 PMID:19549527 GO_REF:0000107 NCBI chr 6:34,537,802...34,556,329
Ensembl chr 6:34,537,802...34,556,333 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEA
IDA		 (PMID:25731159) Ensembl
UniProt		 PMID:25731159 GO_REF:0000107 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23726973) Ensembl
MGI		 PMID:23726973 GO_REF:0000107 NCBI chr12:4,321,213...4,360,028
Ensembl chr12:4,307,763...4,360,028 		JBrowse link
G YAP1 Yes1 associated transcriptional regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:102,110,447...102,233,424
Ensembl chr11:102,110,447...102,233,424 		JBrowse link
G YIPF6 Yip1 domain family member 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22802641) Ensembl
MGI		 PMID:22802641 GO_REF:0000107 NCBI chr  X:68,499,051...68,537,282
Ensembl chr  X:68,498,562...68,537,282 		JBrowse link
intestinal epithelial cell maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in ISO
IEA		 RGD
Ensembl		 PMID:20466941 GO_REF:0000107 RGD:8662316 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G FZD5 frizzled class receptor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15778706) Ensembl
MGI		 PMID:15778706 GO_REF:0000107 NCBI chr 2:207,762,598...207,769,906
Ensembl chr 2:207,762,598...207,769,906 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20808783) Ensembl
MGI		 PMID:20808783 GO_REF:0000107 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HOXA5 homeobox A5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10564089) Ensembl
MGI		 PMID:10564089 GO_REF:0000107 NCBI chr 7:27,141,052...27,143,681
Ensembl chr 7:27,141,052...27,143,681 		JBrowse link
G TMIGD1 transmembrane and immunoglobulin domain containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:33129760) Ensembl
MGI		 PMID:33129760 GO_REF:0000107 NCBI chr17:30,316,333...30,334,057
Ensembl chr17:30,316,333...30,334,059 		JBrowse link
G TYMS thymidylate synthetase involved_in ISO
IEA		 RGD
Ensembl		 PMID:1260861 GO_REF:0000107 RGD:2317427 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578 		JBrowse link
negative regulation of intestinal epithelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR29B1 microRNA 29b-1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 7:130,877,459...130,877,539
Ensembl chr 7:130,877,459...130,877,539 		JBrowse link
G MIR29B2 microRNA 29b-2 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 1:207,802,443...207,802,523
Ensembl chr 1:207,802,443...207,802,523 		JBrowse link
positive regulation of intestinal epithelial cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TLR9 toll like receptor 9 involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19715
    developmental process 7682
      anatomical structure development 7083
        tube development 1432
          digestive tract development 183
            intestinal epithelial cell differentiation 34
              enterocyte differentiation 1
              interstitial cell of Cajal differentiation 0
              intestinal epithelial cell development + 24
Path 2
Term Annotations click to browse term
  biological_process 19715
    developmental process 7682
      anatomical structure development 7083
        tissue development 2490
          epithelium development 1500
            epithelial cell differentiation 903
              columnar/cuboidal epithelial cell differentiation 163
                intestinal epithelial cell differentiation 34
                  enterocyte differentiation 1
                  interstitial cell of Cajal differentiation 0
                  intestinal epithelial cell development + 24
paths to the root