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ONTOLOGY REPORT - ANNOTATIONS

Term:thymus development
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Accession:GO:0048538 term browser browse the term
Definition:The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components.
Comment:Note that this term is reserved for annotation of gene products involved in the formation of the thymus itself, not for gene products involved in T cell differentiation in the thymus or elsewhere.

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thymus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:2065352) Ensembl
MGI		 PMID:2065352 GO_REF:0000107 NCBI chrNW_004936487:17,690,206...17,819,619
Ensembl chrNW_004936487:17,690,968...17,819,669 		JBrowse link
G Adrm1 ADRM1 26S proteasome ubiquitin receptor involved_in ISO (MGI:4849324|PMID:21048919) BHF-UCL PMID:21048919 MGI:4849324 NCBI chrNW_004936514:9,923,956...9,928,168
Ensembl chrNW_004936514:9,923,896...9,928,170 		JBrowse link
G Apc APC regulator of WNT signaling pathway acts_upstream_of_or_within ISO (PMID:16025118)
(PMID:17002498)		 MGI PMID:16025118 PMID:17002498 NCBI chrNW_004936531:6,899,580...7,019,016
Ensembl chrNW_004936531:6,899,788...7,019,453 		JBrowse link
G Asxl1 ASXL transcriptional regulator 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19861679) Ensembl
MGI		 PMID:19861679 GO_REF:0000107 NCBI chrNW_004936485:19,218,494...19,297,188
Ensembl chrNW_004936485:19,227,400...19,298,912 		JBrowse link
G Atm ATM serine/threonine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8843194) Ensembl
MGI		 PMID:8843194 GO_REF:0000107 NCBI chrNW_004936551:359,134...534,672
Ensembl chrNW_004936551:359,362...532,211 		JBrowse link
G Bcl11b BCL11 transcription factor B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12717433) Ensembl
MGI		 PMID:12717433 GO_REF:0000107 NCBI chrNW_004936604:3,023,781...3,110,104
Ensembl chrNW_004936604:3,023,844...3,110,083 		JBrowse link
G Bcl2 BCL2 apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15818405)
(PMID:9241272)		 Ensembl
MGI		 PMID:9241272 PMID:15818405 GO_REF:0000107 NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921 		JBrowse link
G Bcl2l11 BCL2 like 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15818405) Ensembl
MGI		 PMID:15818405 GO_REF:0000107 NCBI chrNW_004936783:15,493...50,959
Ensembl chrNW_004936783:18,194...50,983 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18952847) Ensembl
MGI		 PMID:18952847 GO_REF:0000107 NCBI chrNW_004936592:4,728,371...4,833,830
Ensembl chrNW_004936592:4,737,011...4,834,664 		JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:5037658) Ensembl
MGI		 PMID:5037658 GO_REF:0000107 NCBI chrNW_004936469:25,494,820...25,745,783
Ensembl chrNW_004936469:25,494,883...25,740,223 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO (PMID:23793062) MGI PMID:23793062 NCBI chrNW_004936475:18,036,233...18,049,144
Ensembl chrNW_004936475:18,035,994...18,049,129 		JBrowse link
G Ccnb2 cyclin B2 acts_upstream_of_or_within ISO (PMID:9539739) MGI PMID:9539739 NCBI chrNW_004936471:20,216,435...20,238,543 JBrowse link
G Cited2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20549734) Ensembl
MGI		 PMID:20549734 GO_REF:0000107 NCBI chrNW_004936560:6,353,901...6,356,749
Ensembl chrNW_004936560:6,354,338...6,356,735 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16399080) Ensembl
MGI		 PMID:16399080 GO_REF:0000107 NCBI chrNW_004936619:2,447,686...2,479,589
Ensembl chrNW_004936619:2,447,614...2,479,805 		JBrowse link
G Ctc1 CST telomere replication complex component 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22531781) Ensembl
MGI		 PMID:22531781 GO_REF:0000107 NCBI chrNW_004936595:1,456,911...1,476,331
Ensembl chrNW_004936595:1,454,508...1,476,593 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16025118) Ensembl
MGI		 PMID:16025118 GO_REF:0000107 NCBI chrNW_004936473:29,999,542...30,034,610
Ensembl chrNW_004936473:29,999,562...30,038,293 		JBrowse link
G Ephb3 EPH receptor B3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936578:5,286,580...5,297,369
Ensembl chrNW_004936578:5,287,340...5,298,142 		JBrowse link
G Fadd Fas associated via death domain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:633,501...639,412
Ensembl chrNW_004936599:633,330...639,456 		JBrowse link
G Fgf10 fibroblast growth factor 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936480:18,114,231...18,195,884
Ensembl chrNW_004936480:18,114,204...18,195,898 		JBrowse link
G Fgf3 fibroblast growth factor 3 acts_upstream_of_or_within ISO (PMID:17000704) MGI PMID:17000704 NCBI chrNW_004936599:868,634...875,464
Ensembl chrNW_004936599:868,634...875,464 		JBrowse link
G Foxe1 forkhead box E1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936524:6,619,128...6,620,278
Ensembl chrNW_004936524:6,619,128...6,620,278 		JBrowse link
G Foxi3 forkhead box I3 involved_in ISO (MGI:6360100|PMID:31412026) UniProt PMID:31412026 MGI:6360100 NCBI chrNW_004936712:517,566...522,709
Ensembl chrNW_004936712:517,562...522,925 		JBrowse link
G Foxn1 forkhead box N1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:22072979) RGD
MGI
Ensembl		 PMID:8790387 PMID:22072979 GO_REF:0000107 RGD:1300512 NCBI chrNW_004936538:4,717,509...4,745,504
Ensembl chrNW_004936538:4,731,958...4,744,796 		JBrowse link
G Gata3 GATA binding protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17082577) Ensembl
MGI		 PMID:17082577 GO_REF:0000107 NCBI chrNW_004936484:6,780,692...6,800,883
Ensembl chrNW_004936484:6,780,692...6,800,966 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936516:4,692,926...4,695,625
Ensembl chrNW_004936516:4,692,926...4,695,632 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936711:640,002...642,580
Ensembl chrNW_004936711:639,905...642,622 		JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K ISO RGD PMID:16488668 RGD:10002779 NCBI chrNW_004936828:827,660...839,088
Ensembl chrNW_004936828:828,837...838,720 		JBrowse link
G Hoxa3 homeobox A3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9520319)
(PMID:7635047)
(PMID:11476574)		 Ensembl
MGI		 PMID:7635047 PMID:9520319 PMID:11476574 GO_REF:0000107 NCBI chrNW_004936478:3,735,509...3,767,899
Ensembl chrNW_004936478:3,735,505...3,767,899 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO (PMID:7923373) MGI PMID:7923373 NCBI chrNW_004936686:1,459,582...1,556,478
Ensembl chrNW_004936686:1,462,145...1,556,451 		JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9376320) Ensembl
MGI		 PMID:9376320 GO_REF:0000107 NCBI chrNW_004936552:1,566,382...1,786,837
Ensembl chrNW_004936552:1,566,788...1,785,490 		JBrowse link
G Lmo4 LIM domain only 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20549734) Ensembl
MGI		 PMID:20549734 GO_REF:0000107 NCBI chrNW_004936732:1,541,511...1,557,845
Ensembl chrNW_004936732:1,541,515...1,555,735 		JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 acts_upstream_of_or_within ISO (PMID:11313860) MGI PMID:11313860 NCBI chrNW_004936754:1,842,588...1,957,116 JBrowse link
G Mafb MAF bZIP transcription factor B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19164599) Ensembl
MGI		 PMID:19164599 GO_REF:0000107 NCBI chrNW_004936561:1,007,273...1,010,548
Ensembl chrNW_004936561:1,007,647...1,008,618 		JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18952847) Ensembl
MGI		 PMID:18952847 GO_REF:0000107 NCBI chrNW_004936471:26,589,251...26,628,302
Ensembl chrNW_004936471:26,589,161...26,628,302 		JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18952847) Ensembl
MGI		 PMID:18952847 GO_REF:0000107 NCBI chrNW_004936588:2,338,127...2,377,090
Ensembl chrNW_004936588:2,336,858...2,377,090 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18952847) Ensembl
MGI		 PMID:18952847 GO_REF:0000107 NCBI chrNW_004936619:1,889,841...1,932,646
Ensembl chrNW_004936619:1,889,708...1,932,646 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18952847) Ensembl
MGI		 PMID:18952847 GO_REF:0000107 NCBI chrNW_004936501:12,342,670...12,390,650
Ensembl chrNW_004936501:12,384,804...12,392,180 		JBrowse link
G Myb MYB proto-oncogene, transcription factor acts_upstream_of_or_within ISO (PMID:17927961) MGI PMID:17927961 NCBI chrNW_004936560:2,797,943...2,828,813
Ensembl chrNW_004936560:2,796,697...2,829,650 		JBrowse link
G Nfatc3 nuclear factor of activated T cells 3 acts_upstream_of_or_within ISO (PMID:9768749) MGI PMID:9768749 NCBI chrNW_004936475:18,462,424...18,557,832
Ensembl chrNW_004936475:18,462,298...18,555,220 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1 group H member 3 ISO RGD PMID:17341476 RGD:401827282 NCBI chrNW_004936562:1,937,665...1,946,680
Ensembl chrNW_004936562:1,937,667...1,946,669 		JBrowse link
G Pax1 paired box 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11476574) Ensembl
MGI		 PMID:11476574 GO_REF:0000107 NCBI chrNW_004936620:3,765,481...3,773,779
Ensembl chrNW_004936620:3,765,444...3,776,467 		JBrowse link
G Pbx1 PBX homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15581866) Ensembl
MGI		 PMID:15581866 GO_REF:0000107 NCBI chrNW_004936481:20,200,236...20,440,623
Ensembl chrNW_004936481:20,203,405...20,440,629 		JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of_or_within ISO (PMID:15259009) MGI PMID:15259009 NCBI chrNW_004936659:1,894,423...1,897,690 JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO RGD PMID:22981234 RGD:8696027 NCBI chrNW_004936590:4,722,914...4,887,615
Ensembl chrNW_004936590:4,722,873...4,890,156 		JBrowse link
G Psen1 presenilin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17698590) Ensembl
MGI		 PMID:17698590 GO_REF:0000107 NCBI chrNW_004936488:2,464,623...2,528,807
Ensembl chrNW_004936488:2,464,527...2,530,065 		JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO (PMID:17698590) MGI PMID:17698590 NCBI chrNW_004936526:3,584,194...3,611,719
Ensembl chrNW_004936526:3,584,188...3,614,074 		JBrowse link
G Psmb9 proteasome 20S subunit beta 9 ISO RGD PMID:18457575 RGD:9850287 NCBI chrNW_004936476:25,894,313...25,899,132
Ensembl chrNW_004936476:25,894,027...25,899,319 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18952847) Ensembl
MGI		 PMID:18952847 GO_REF:0000107 NCBI chrNW_004936602:1,089,979...1,114,376
Ensembl chrNW_004936602:1,051,205...1,117,096 		JBrowse link
G Rag1 recombination activating 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18684012) Ensembl
MGI		 PMID:18684012 GO_REF:0000107 NCBI chrNW_004936533:1,817,135...1,827,393
Ensembl chrNW_004936533:1,817,135...1,827,393 		JBrowse link
G Ripk3 receptor interacting serine/threonine kinase 3 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chrNW_004936722:209,019...212,817
Ensembl chrNW_004936722:209,013...212,839 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936527:10,033,095...10,042,713
Ensembl chrNW_004936527:10,033,299...10,042,599 		JBrowse link
G Six1 SIX homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16530750) Ensembl
MGI		 PMID:16530750 GO_REF:0000107 NCBI chrNW_004936495:4,839,496...4,842,906
Ensembl chrNW_004936495:4,838,051...4,842,994 		JBrowse link
G Six4 SIX homeobox 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16530750) Ensembl
MGI		 PMID:16530750 GO_REF:0000107 NCBI chrNW_004936495:4,887,718...4,900,198
Ensembl chrNW_004936495:4,887,718...4,900,198 		JBrowse link
G Slc46a2 solute carrier family 46 member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18684012) Ensembl
MGI		 PMID:18684012 GO_REF:0000107 NCBI chrNW_004936559:670,239...674,061
Ensembl chrNW_004936559:670,231...679,766 		JBrowse link
G Srf serum response factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18952847) Ensembl
MGI		 PMID:18952847 GO_REF:0000107 NCBI chrNW_004936476:16,779,941...16,789,499
Ensembl chrNW_004936476:16,782,233...16,789,130 		JBrowse link
G Tbx1 T-box transcription factor 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:14585638)
(PMID:17916582)
(MGI:6360100|PMID:31412026)		 UniProt
MGI		 PMID:14585638 PMID:17916582 PMID:31412026 MGI:6360100 NCBI chrNW_004936619:3,662,567...3,670,470
Ensembl chrNW_004936619:3,664,468...3,670,525 		JBrowse link
G Tgfbr1 transforming growth factor beta receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17078885) Ensembl
MGI		 PMID:17078885 GO_REF:0000107 NCBI chrNW_004936524:7,656,523...7,680,043
Ensembl chrNW_004936524:7,655,847...7,681,097 		JBrowse link
G Tyr tyrosinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10890980) Ensembl
MGI		 PMID:10890980 GO_REF:0000107 NCBI chrNW_004936736:421,623...519,085
Ensembl chrNW_004936736:421,598...519,253 		JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 involved_in ISO (MGI:5300225|PMID:22201126) UniProt PMID:22201126 MGI:5300225 NCBI chrNW_004936495:8,212,136...8,238,876 JBrowse link
G Zmpste24 zinc metallopeptidase STE24 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11923874) Ensembl
MGI		 PMID:11923874 GO_REF:0000107 NCBI chrNW_004936474:22,035,059...22,077,846
Ensembl chrNW_004936474:22,034,801...22,077,986 		JBrowse link
thymus epithelium morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aire autoimmune regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936500:125,589...137,071
Ensembl chrNW_004936500:125,795...137,056 		JBrowse link
G Foxn1 forkhead box N1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936538:4,717,509...4,745,504
Ensembl chrNW_004936538:4,731,958...4,744,796 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15975
    immune system process 2209
      immune system development 226
        hematopoietic or lymphoid organ development 126
          thymus development 61
            neural crest cell differentiation involved in thymus development 0
            thymus epithelium morphogenesis + 2
Path 2
Term Annotations click to browse term
  biological_process 15975
    developmental process 6338
      anatomical structure development 5971
        multicellular organism development 4846
          system development 4223
            immune system development 226
              hematopoietic or lymphoid organ development 126
                thymus development 61
                  neural crest cell differentiation involved in thymus development 0
                  thymus epithelium morphogenesis + 2
paths to the root