Adrm1 (ADRM1 26S proteasome ubiquitin receptor)

Gene: Adrm1 (ADRM1 26S proteasome ubiquitin receptor) Ictidomys tridecemlineatus

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Symbol:

Adrm1

Name:

ADRM1 26S proteasome ubiquitin receptor (Ensembl:adhesion regulating molecule 1)

RGD ID:

12703974

Description:

ENCODES a protein that exhibits molecular function inhibitor activity (ortholog); INVOLVED IN adipose tissue development (ortholog); follicle-stimulating hormone signaling pathway (ortholog); oogenesis (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy (ortholog); developmental and epileptic encephalopathy 33 (ortholog); early infantile epileptic encephalopathy (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

adhesion regulating molecule 1; proteasomal ubiquitin receptor ADRM1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	194,470,280 - 194,474,527 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936514	9,923,896 - 9,928,170 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936514	9,923,956 - 9,928,168 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

developmental and epileptic encephalopathy (ISO)

developmental and epileptic encephalopathy 33 (ISO)

early infantile epileptic encephalopathy (ISO)

genetic disease (ISO)

neuronal ceroid lipofuscinosis (ISO)

prostate cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adipose tissue development (ISO)

follicle-stimulating hormone signaling pathway (ISO)

oogenesis (ISO)

ovarian follicle development (ISO)

positive regulation of growth hormone receptor signaling pathway (ISO)

proteasome assembly (IEA)

regulation of T cell differentiation in thymus (ISO)

seminiferous tubule development (ISO)

Sertoli cell development (ISO)

spermatid development (ISO)

thymus development (ISO)

transcription elongation by RNA polymerase II (IEA)

Cellular Component

cytoplasm (IEA)

cytosol (IEA)

nucleoplasm (IEA)

nucleus (IEA)

plasma membrane (IEA)

proteasome complex (IEA)

proteasome regulatory particle, lid subcomplex (IEA)

Molecular Function

endopeptidase activator activity (IEA)

molecular function inhibitor activity (ISO)

protease binding (IEA)

proteasome binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Adrm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	194,470,280 - 194,474,527 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936514	9,923,896 - 9,928,170 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936514	9,923,956 - 9,928,168 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ADRM1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	62,302,896 - 62,308,862 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	62,302,093 - 62,308,862 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	60,877,952 - 60,883,918 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	60,311,422 - 60,317,313 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	20	60,311,421 - 60,317,311	NCBI
Celera	20	57,613,180 - 57,619,071 (+)	NCBI		Celera
Cytogenetic Map	20	q13.33	NCBI
HuRef	20	57,653,756 - 57,659,722 (+)	NCBI		HuRef
CHM1_1	20	60,778,716 - 60,784,682 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	64,093,845 - 64,099,811 (+)	NCBI		T2T-CHM13v2.0

Adrm1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	179,813,381 - 179,818,076 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	179,813,278 - 179,818,079 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	180,171,588 - 180,176,283 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	180,171,485 - 180,176,286 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	179,906,293 - 179,910,988 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	180,100,996 - 180,105,691 (+)	NCBI		MGSCv36	mm8
Celera	2	184,253,798 - 184,258,493 (+)	NCBI		Celera
Cytogenetic Map	2	H4	NCBI
cM Map	2	102.69	NCBI

Adrm1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	187,643,043 - 187,647,805 (+)	NCBI		GRCr8
mRatBN7.2	3	167,265,435 - 167,270,197 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	167,265,296 - 167,270,195 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	171,642,409 - 171,647,171 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	180,601,497 - 180,606,259 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	177,266,396 - 177,271,158 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	175,548,181 - 175,552,943 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	175,548,174 - 175,552,947 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	181,565,740 - 181,570,623 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	169,229,036 - 169,233,798 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	169,135,071 - 169,139,832 (+)	NCBI
Celera	3	165,309,978 - 165,314,740 (-)	NCBI		Celera
Cytogenetic Map	3	q43	NCBI

Adrm1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955528	1,753,450 - 1,759,886 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955528	1,753,450 - 1,759,886 (-)	NCBI	ChiLan1.0	ChiLan1.0

ADRM1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	68,080,660 - 68,089,308 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	68,075,792 - 68,082,430 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	58,667,601 - 58,673,566 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	59,985,358 - 59,991,668 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	59,985,358 - 59,991,668 (+)	Ensembl	panpan1.1		panPan2

ADRM1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	46,309,478 - 46,314,892 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	46,275,175 - 46,491,347 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	45,545,977 - 45,551,893 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	47,165,587 - 47,171,518 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	47,165,587 - 47,171,518 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	46,266,793 - 46,272,718 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	46,390,031 - 46,395,966 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	47,144,420 - 47,150,335 (+)	NCBI		UU_Cfam_GSD_1.0

ADRM1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	61,692,945 - 61,698,144 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	61,692,923 - 61,698,138 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

ADRM1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	1,930,281 - 1,936,323 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	1,925,382 - 1,936,393 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	49,877,847 - 49,883,920 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Adrm1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624741	28,151,643 - 28,156,828 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624741	28,151,404 - 28,156,830 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005325303	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040275794	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010003700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000002696 ⟹ ENSSTOP00000002412

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936514	9,923,896 - 9,928,170 (+)	Ensembl

RefSeq Acc Id:

ENSSTOT00000035356 ⟹ ENSSTOP00000029226

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936514	9,924,124 - 9,928,039 (+)	Ensembl

RefSeq Acc Id:

XM_005325303 ⟹ XP_005325360

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	194,470,286 - 194,474,527 (+)	NCBI
SpeTri2.0	NW_004936514	9,923,956 - 9,928,168 (+)	NCBI

Sequence:

show sequence

CTTGGGTGCACTTGAGAAGCCGAGAAGCCACAGGCCCGGCCTGGGTCTTGGCCCGTTGGCCGGG
CGCCGTAGGGCTGGCCGACACTGGGGCGGGGGGCGGCGGCTAGCTTTTCGGGATCGTGCCCGCC
CGCAGCTCGCTGGGCCTCGTGCCCGTCTTTGCTTTTCAGGATGACGACTTCAGGCGCGCTGTTC
CCAAGCCTGGTGCCAGGCTCTCGGGGGTCCTCCAATAAGTATCTGGTGGAGTTTCGGGCAGGGA
AAATGTCATTGAAAGGCACTACTGTCACTCCGGACAAGCGGAAAGGGCTCGTGTACATCCAGCA
GACAGACGACTCTCTCATTCACTTCTGCTGGAAGGACAGGACATCTGGGACCGTGGAAGATGAC
TTGATTATCTTCCCTGACGACTGTGAGTTCAAGCGCGTGCCTCAGTGCCCCAGCGGGAGGGTCT
ACGTGCTCAAGTTCAAGGCTGGGTCCAAGCGGCTCTTCTTCTGGATGCAGGAGCCCAAGACCGA
CCAGGACGAGGAGCACTGCCGGAAAGTCAACGAGTACCTGAACAACCCCCCGATGCCCGGGGCG
CTGGGCGCGAGTGGGAGTGGGGGCCACGAGCTCTCCGCACTGGGCGGTGAGGGTGGCCTACAGA
GCCTGCTGGGGAACATGAGTCACAGCCAGCTCATGCAGCTCATCGGACCAGCCGGCCTCGGAGG
ACTGGGTGGGCTTGGGGCTCTGACTGGGCCGGGCCTGGCCAGCTTACTGGGCAGTGGTGGGCCT
CCTGCGAGCAGCTCTTCGTCCAGCTCCCGGAGCCAGTCAGCAGCAGTCACCCCGTCCTCCACCA
CCTCTTCCACCCGAGCCACCCCAGCCCCTTCTGCCCCAGCCGCCGCCGCAGCGACCAGCCCCAG
CCCTGCACCCAGCTCAGGTACTGGGACCAGCGCGGCAGCCAGCCCCGCCCAGCCCATCCAGTTG
AGCGACCTCCAGAGTATCCTAGCTACCATGAGCGTGCCGGCGGGGCCAGGGGGCAGCCAGCAAG
TGGACCTGGCCAGCGTGCTGACGCCAGAGATCATGGCACCCATCCTCGCCAACGCGGACGTCCA
GGAGCGCCTGCTGCCGTACCTGCCCTCGGGGGAGTCGCTGCCCCAGACTGCAGAGGAGATCCAG
AACACACTGACCTCGCCCCAGTTCCAGCAGGCCCTGGGCATGTTCAGCGCAGCCTTGGCCTCGG
GGCAGCTGGGGCCCCTCATGTGCCAGTTCGGCCTTCCAGCAGAGGCCGTGGAGGCCGCCAACAA
GGGTGATGTGGAAGCCTTTGCCAAAGCCATGCAGAACAGCGCCAAATCAGAGCCGAAGGAGGGC
GACGCCAAGGACAAGAAGGACGAGGAGGAGGACATGAGTCTAGACTAAGTTACGGGTGGGGCGC
AGGGTCGGCGTGCAACCGCGCGCTCCTGCTCCTTGGTGGCGGTTGGGATCCTGCGCAACCAACG
CTCCTCCCTTCAGACTTACTGATAAATAAAGGTCCTTTCTTTTACCTGC

hide sequence

RefSeq Acc Id:

XM_040275794 ⟹ XP_040131728

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	194,470,280 - 194,474,527 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_005325360	(Get FASTA)	NCBI Sequence Viewer
	XP_040131728	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000002412.2
	ENSSTOP00000029226.1
GenBank Protein	KAG3263624	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005325360 ⟸ XM_005325303
- Peptide Label:	isoform X2
- UniProtKB:	I3M0X6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTTSGALFPSLVPGSRGSSNKYLVEFRAGKMSLKGTTVTPDKRKGLVYIQQTDDSLIHFCWKDR TSGTVEDDLIIFPDDCEFKRVPQCPSGRVYVLKFKAGSKRLFFWMQEPKTDQDEEHCRKVNEYL NNPPMPGALGASGSGGHELSALGGEGGLQSLLGNMSHSQLMQLIGPAGLGGLGGLGALTGPGLA SLLGSGGPPASSSSSSSRSQSAAVTPSSTTSSTRATPAPSAPAAAAATSPSPAPSSGTGTSAAA SPAQPIQLSDLQSILATMSVPAGPGGSQQVDLASVLTPEIMAPILANADVQERLLPYLPSGESL PQTAEEIQNTLTSPQFQQALGMFSAALASGQLGPLMCQFGLPAEAVEAANKGDVEAFAKAMQNS AKSEPKEGDAKDKKDEEEDMSLD hide sequence

RefSeq Acc Id:	XP_040131728 ⟸ XM_040275794
- Peptide Label:	isoform X1

RefSeq Acc Id:

ENSSTOP00000029226 ⟸ ENSSTOT00000035356

RefSeq Acc Id:

ENSSTOP00000002412 ⟸ ENSSTOT00000002696

Protein Domains

DEUBAD Pru

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000002691	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000002696.3	UniProtKB/TrEMBL
	ENSSTOT00000035356.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.2020.20	UniProtKB/TrEMBL
	2.30.29.70	UniProtKB/TrEMBL
InterPro	DEUBAD_dom	UniProtKB/TrEMBL
	Rpn13/ADRM1	UniProtKB/TrEMBL
	Rpn13/ADRM1_Pru	UniProtKB/TrEMBL
	Rpn13/ADRM1_Pru_sf	UniProtKB/TrEMBL
	RPN13_DEUBAD	UniProtKB/TrEMBL
	RPN13_DEUBAD_sf	UniProtKB/TrEMBL
NCBI Gene	Adrm1	ENTREZGENE
PANTHER	PROTEASOMAL UBIQUITIN RECEPTOR ADRM1	UniProtKB/TrEMBL
	PTHR12225	UniProtKB/TrEMBL
Pfam	Proteasom_Rpn13	UniProtKB/TrEMBL
	RPN13_C	UniProtKB/TrEMBL
PROSITE	DEUBAD	UniProtKB/TrEMBL
	PRU	UniProtKB/TrEMBL
UniProt	A0A287D6T1_ICTTR	UniProtKB/TrEMBL
	I3M0X6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-02	Adrm1	ADRM1 26S proteasome ubiquitin receptor	Adrm1	adhesion regulating molecule 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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