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Gene: Fadd (Fas associated via death domain) Ictidomys tridecemlineatus

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Symbol:

Fadd

Name:

Fas associated via death domain

RGD ID:

12468181

Description:

ENCODES a protein that exhibits death receptor binding (ortholog); protease binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN behavioral response to cocaine (ortholog); extrinsic apoptotic signaling pathway (ortholog); extrinsic apoptotic signaling pathway in absence of ligand (ortholog); PARTICIPATES IN ceramide signaling pathway; FasL mediated signaling pathway; Trail mediated signaling pathway; ASSOCIATED WITH abdominal obesity-metabolic syndrome 1 (ortholog); Acute Lung Injury (ortholog); acute myeloid leukemia (ortholog); FOUND IN CD95 death-inducing signaling complex (ortholog); cell body (ortholog); death-inducing signaling complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

Fas associated via death domain, transcript variant X1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	4,192,521 - 4,197,087 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936599	633,330 - 639,456 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936599	633,501 - 639,412 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

abdominal obesity-metabolic syndrome 1 (ISO)

Acute Lung Injury (ISO)

acute myeloid leukemia (ISO)

Aicardi-Goutieres Syndrome 3 (ISO)

Alzheimer's disease (ISO)

brain glioma (ISO)

Brain Hypoxia-Ischemia (ISO)

Carbon Tetrachloride Poisoning (ISO)

Chemical and Drug Induced Liver Injury (ISO)

Chronic Intermittent Hypoxia (ISO)

Craniofacial Abnormalities (ISO)

depressive disorder (ISO)

Diabetic Embryopathy (ISO)

genetic disease (ISO)

Hyperoxia (ISO)

hypertension (ISO)

intellectual disability (ISO)

leukemia (ISO)

Liver Reperfusion Injury (ISO)

Metabolic Syndrome (ISO)

middle cerebral artery infarction (ISO)

morphine dependence (ISO)

Myocardial Reperfusion Injury (ISO)

Neoplasm Metastasis (ISO)

obesity (ISO)

oculoauricular syndrome (ISO)

prostatic hypertrophy (ISO)

Recurrent Infections, with Encephalopathy, Hepatic Dysfunction, and Cardiovascular Malformations (ISO)

sensorineural hearing loss (ISO)

Spinal Cord Injuries (ISO)

Stomatognathic Diseases (ISO)

transient cerebral ischemia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic process (IEA)

apoptotic signaling pathway (IEA)

behavioral response to cocaine (ISO)

cellular response to mechanical stimulus (IEA)

death-inducing signaling complex assembly (IEA)

defense response to virus (IEA)

extrinsic apoptotic signaling pathway (IEA,ISO)

extrinsic apoptotic signaling pathway in absence of ligand (IEA,ISO)

extrinsic apoptotic signaling pathway via death domain receptors (IEA)

innate immune response (IEA)

kidney development (ISO)

lymph node development (IEA)

motor neuron apoptotic process (IEA,ISO)

necroptotic signaling pathway (IEA)

negative regulation of activation-induced cell death of T cells (IEA)

negative regulation of necroptotic process (IEA,ISO)

positive regulation of activated T cell proliferation (IEA)

positive regulation of adaptive immune response (IEA)

positive regulation of apoptotic process (IEA)

positive regulation of canonical NF-kappaB signal transduction (IEA)

positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation (IEA)

positive regulation of execution phase of apoptosis (IEA)

positive regulation of extrinsic apoptotic signaling pathway (IEA,ISO)

positive regulation of innate immune response (IEA)

positive regulation of interleukin-8 production (IEA)

positive regulation of macrophage differentiation (IEA)

positive regulation of proteolysis (IEA)

positive regulation of T cell mediated cytotoxicity (IEA)

positive regulation of transcription by RNA polymerase II (IEA)

positive regulation of tumor necrosis factor production (IEA)

positive regulation of type I interferon-mediated signaling pathway (IEA)

positive regulation of type II interferon production (IEA)

regulation of apoptotic process (IEA)

regulation of necroptotic process (ISO)

response to cocaine (ISO)

signal transduction (IEA)

spleen development (IEA)

T cell differentiation in thymus (IEA)

T cell homeostasis (IEA)

thymus development (IEA)

TRAIL-activated apoptotic signaling pathway (IEA)

Cellular Component

CD95 death-inducing signaling complex (IEA,ISO)

cell body (ISO)

cytoplasm (IEA)

cytosol (IEA)

death-inducing signaling complex (IEA,ISO)

plasma membrane (IEA)

protein-containing complex (ISO)

ripoptosome (IEA)

Molecular Function

caspase binding (IEA)

death effector domain binding (IEA)

death receptor binding (IEA,ISO)

identical protein binding (IEA)

protease binding (IEA,ISO)

protein binding (ISO)

protein-containing complex binding (ISO)

protein-macromolecule adaptor activity (IEA)

receptor serine/threonine kinase binding (ISO)

signaling adaptor activity (IEA)

tumor necrosis factor receptor binding (ISO)

tumor necrosis factor receptor superfamily binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

ceramide signaling pathway (ISO)

FasL mediated signaling pathway (ISO)

Trail mediated signaling pathway (ISO)

tumor necrosis factor mediated signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Fadd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	4,192,521 - 4,197,087 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936599	633,330 - 639,456 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936599	633,501 - 639,412 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FADD
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	70,203,296 - 70,207,390 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	70,203,296 - 70,207,390 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	70,049,402 - 70,053,496 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	69,726,917 - 69,731,144 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	69,726,916 - 69,731,134	NCBI
Celera	11	67,315,851 - 67,320,090 (+)	NCBI		Celera
Cytogenetic Map	11	q13.3	NCBI
HuRef	11	66,308,990 - 66,313,229 (+)	NCBI		HuRef
CHM1_1	11	69,932,172 - 69,936,414 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	70,218,250 - 70,222,344 (+)	NCBI		T2T-CHM13v2.0

Fadd
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	144,132,060 - 144,136,178 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	144,131,055 - 144,136,200 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	144,578,323 - 144,582,441 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	144,577,318 - 144,582,463 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	151,764,228 - 151,768,341 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	144,387,713 - 144,391,826 (-)	NCBI		MGSCv36	mm8
Celera	7	144,342,191 - 144,346,305 (-)	NCBI		Celera
Cytogenetic Map	7	F5	NCBI
cM Map	7	88.85	NCBI

Fadd
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	209,169,245 - 209,175,423 (-)	NCBI		GRCr8
mRatBN7.2	1	199,743,200 - 199,745,746 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	199,739,994 - 199,745,653 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	208,126,497 - 208,128,902 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	215,210,505 - 215,212,909 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	207,884,688 - 207,887,092 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	217,746,176 - 217,748,581 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	217,742,929 - 217,748,628 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	224,603,556 - 224,605,961 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	205,010,363 - 205,012,768 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	205,163,017 - 205,166,234 (-)	NCBI
Celera	1	197,302,715 - 197,305,120 (-)	NCBI		Celera
Cytogenetic Map	1	q42	NCBI

Fadd
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	16,031,280 - 16,036,281 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	16,026,323 - 16,035,808 (-)	NCBI	ChiLan1.0	ChiLan1.0

FADD
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	71,170,462 - 71,177,552 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	72,214,724 - 72,218,869 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	65,300,889 - 65,305,020 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	68,590,184 - 68,593,905 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

FADD
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	48,087,447 - 48,094,497 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	46,692,062 - 46,704,606 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	48,765,020 - 48,771,948 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	48,765,607 - 48,771,913 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	48,212,163 - 48,219,087 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	47,792,264 - 47,804,830 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	48,543,968 - 48,550,895 (-)	NCBI		UU_Cfam_GSD_1.0

FADD
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	3,185,675 - 3,194,818 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	3,191,718 - 3,194,820 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	1,388,619 - 1,389,394 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FADD
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	4,358,314 - 4,361,863 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666038	101,642,664 - 101,647,269 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fadd
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624767	17,055,509 - 17,059,705 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624767	17,050,929 - 17,059,648 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005333312	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002484810	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000030620 ⟹ ENSSTOP00000024623

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936599	633,330 - 639,456 (-)	Ensembl

RefSeq Acc Id:

XM_005333312 ⟹ XP_005333369

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404947	4,192,521 - 4,197,087 (-)	NCBI
SpeTri2.0	NW_004936599	633,665 - 639,412 (-)	NCBI

Sequence:

show sequence

TTCGAATCGGAAACCCGAGTGCCGGGGGCTGGGTGGGCGCGGGGCGTGCAGGCTGCTCGCCGGC
GCCGCCATGGACCCCTTCCGGGTGCTGCTGCACTCGGTGTCGGCCGACCTGTCCAGCGGCGAGC
TGACCGAGCTCAAGTTCCTGTGCCAGGGGCTAGTGGGCAAGAGGAAGCTGGAGCGCGTGCAGCG
CGGCCACGAGCTCTTCGAGGTGCTGCTGGAGCAGAAGGACCTGGAGGCCGAGCACACCGGGCTG
CTGCGCGACCTGCTGGCCTCGCTGCGGCGCCACGACCTGCTGCAGCGCCTGGACGACTTCGAGG
TGGGGGCGGCGGCGGGGGCCGCGCAGGAGGAGGCAGATCTGCACGCAGCCTTCAGCATCATATG
TGATAATGTGGGGAAAGACTGGAGGAGACTGGCTCGTCACCTTGGAGTTTCTGACGCCAAGATC
GATGGAATTGAGGAGCGATACCCCCGCAACCTGGCAGAGCGGGTGCGGGAGTCGCTGAGAGTGT
GGAAGAGCAGCGAGCGGGAGAAGGCCACAGTGGCTGGCTTGGTCGAGGCGCTCAGGGCCTGTCG
GATGAACCTGGTGGCCGACCTCGTGGAGGAGGAGCAGCTGGCCCGGCAGCTCCAAAACGGGAGT
GACGCTGTGTCCCCAGTGCAGTGGGACTCGGACGCTCACACCTCAGAAGCTCCTTGATGGGGCT
GCCGTTCTCCTTGGGGACCATGGGAGGGACTTGATTCTCTGTACCATGCCCAGCACTGGGCAGT
CCCATCAGGAGCCAGGCAGAGGGCTCCCCCTCAGAGCCACGCTGCAGCTTCACAGTTAAAGCTG
CGTTTCCTGAGCCCCTCCTCTGCCAGGCGGGGCCTGGAGTGCGGGTGAGGGAGGGGGCTTCTGC
CATCTTCACTCAGCTTTGGGCACAAAGGCACTCGTTCAGATTGAGTCCTACCTGTTCTTCAGGT
GAGGAAACGGGCTGGAGGGAGGTCAGAACCGGGACAGCGCATCTGGCTCCGGAGAAGGGCCTTC
TAACCAGCGTGTCCCACGGTGACTCCACCGTGGACAAAAGGCACATTTTGTCCCATTCTTTGAG
GCGACAGGGTAGACCTGGACACCAGCACGAGGTGCTGTCCTGGTCCAGGAGTCAGGACGCCTGG
CTGACTCACAGAGCGGCGACAGCAGGGCTGTGAGGGTGACCACAGTGACGCCTGTGGAGTGCTC
CTAGGAACTGGTGCACAGCCGAGCTCCTCCACCGTCAGTCCTCGCAAGGAGCCGGTTCCCGGGT
CGCAGGTGGCTGTTCTGTGTCAGAATTACCATCCAGGCGGTCATTGGCCTAGCAAGGGGCAAGA
CCCTGGGCCTCCAGAGCCCTCCACTGAAGCCAGTGCCTTTACCCGGAGCCCTCCAGGCGCCTCT
GGAAACCAGTTGACCCAACTGGAGCCTGTTTCCCGAAGAGGTCACGTCACAAAGAACTCCCACT
CCCGACGATGACTTTCTCGTCACGTATTCTGAGGGGTCATTCCAGCTGGTGTCAGCAGCTCGTC
CTGGGCTCTCCCTATGGAAATGGCGGCAGGATTATCATAGCTTGCTCACCCCTAGCCAGAGTAT
TGATCTAAGCCAGAGGTGATCTGCAGAAGGCAGGTCTGCCACCTGTGGGACCTGCCTGCGCCTG
CCAGACATGGTTATGGTTCTGGAATGTTGTCCAGGAGTGGTGCTTTTACCAGGAGTGGGTCGGC
CAGGCGTGTGGCGGAGGCCGGGTTGGAAGCTGGAGACCAGCCTCAGCAACTGAGCAAGGCTCGA
GGCGGCCTAGGAAGACCCTGTCTGGAACTCAGGGGTAGGGCTGCGGCCTGGTGGTTAAGACCCC
GAGTTTGAGGCCCAGTACCAAAAAAGAAGAGTGGCACGGATCACGTGGCTTTAACCTCACCAGC
GGATTCATCCGTTTAGCGTGTCTAATGGTTCAGGTGTGAAGTGTGCCCCCAAGCTCCTACGTGA
GACAGTGCAGGGAAGTTCAGAGGTGAAATACACCTGGTCAGTGAGTTGATCCCCGATAGGGGTT
GACTGAGTGGTGACTGTGAGCAGGTCGGGTGTGACAGGACAGGTGGGTCCCTCGAGGTGGGCTT
CTCTTTGGTCCTTGGTGAGAGGACTTTCTCTCTGCTTCCTGACTGTCCTCTCCTGAGCTGCCTT
CCTCCACCACACTCTTCCACCACGATGTCCTGCCTCACCTCCGCCCAAAGCAGTGGGGTTCGCT
GTCTGTGGACTGAGACCTCCTAAACCGTGAGTGCCAAATAAACTTTTCTTCTTCTAAAAACATT
CTCGTCCCGTCTTTTGGTCACAGGGCAAAAAAGCTGGACTGAAACACGTTGGTACCGAGAAATG
GGTTGTTGCTGTGATTAATGGTTCAGAAGCTTTGGAGCTTTTTGGAATTTGTGGGAGCAATTTG
AAAAGTTTAGAGATGCAAACTGGAGAAGTTTTAGATTGTTGTAAGCCAGGCTCAATATGCGGTT
CTGGTGGGAGCTCAGAAAACCAGGATGCCAAGAGGCTGCAGGCAGTGAGCCTGCTCAGGAGGCC
TCAGAGCAGGAGGAGGACTCTTGGAAATGGGTCTGGAGACCGTTCACAGGACGCCCTGGCTAAG
AAGACATCAGCATGTGTTCCACGTCCTGAGACTTGGAGGGGTTGAATTCAGTCTGGCAGTAGAA
ATCTCTAGGCAGCACAGCTTTCGTGTGGAGGCGTGGGTATTGCCGGCAGCTTCTAGCCAAGTTT
ATTGTGAGAATCGGGAACAGGAAGCAAAAAGATTTTAAAAACTTGCAGTTTAGCCAGAAAACTT
TGAGTAAAACCGAGGTCAAGGAAGGTGTGGTGTTGAACACAATACAGCCGCTAAACACTAAATA
TTTTACCTAGAAACACTAGGAAAGATGGTTCGAGGGCATCTTAGGAACTGGCAAGATATCACCC
ATCTGAGGCTCAAGGGTGTAAGAATAGAAATTCCTTTGTTTGGAGACCAATGGACACCCTGCCT
GTACAGGGGCCCTGGGAAGTTTTTCAGCAGGCTCAGCCCCCAGCACTCAGGCTGCTGCTGCCAG
GATCCCCGGAGGCTCTGCTGCTGCTCGAGGTGGTGGCAGCACGTGGTGCTGGTTATGCAGGATG
CAGGATGCTGGCGTTGGGGCCCTGCAGGCTTCTGCTGAGCTGGCACGTGCGAGGCCAGGCAAGG
TGCTGAGGTCCCTGTCACTGCGCAGGGACGAGAGGGAGGCTGTGGAAGTAAAGCCAGCGCGGCA
GTGAGGACCCCAAGGTAGGCCAGGAGTGGGGACTGTGCTGAGAAAAGCTGCAGGCAGTGGGTAG
AGGCAGCCCAGCAGAGTCCCCACAGGCTGCGCCTGCTAAGGCCAGGAGCCGCGCCGCACCGGCC
CTGTGGAGCCCACGTCCTGCCGCCACATGCCTGGGTGCCAGGCGTGGACTCCAGGGACTCGCTT
GGTCCCCATCTCCCTGCATCCTCACTCTTTTCTTTGCCATTGTGTATGGGG

hide sequence

Protein Sequences


Protein RefSeqs	XP_005333369	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000024623.1
GenBank Protein	KAG3284463	(Get FASTA)	NCBI Sequence Viewer
	KAG3284464	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005333369 ⟸ XM_005333312

- UniProtKB:

A0A287CTM4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDPFRVLLHSVSADLSSGELTELKFLCQGLVGKRKLERVQRGHELFEVLLEQKDLEAEHTGLLR
DLLASLRRHDLLQRLDDFEVGAAAGAAQEEADLHAAFSIICDNVGKDWRRLARHLGVSDAKIDG
IEERYPRNLAERVRESLRVWKSSEREKATVAGLVEALRACRMNLVADLVEEEQLARQLQNGSDA
VSPVQWDSDAHTSEAP

hide sequence

Ensembl Acc Id:

ENSSTOP00000024623 ⟸ ENSSTOT00000030620

Protein Domains

Death DED

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000033252	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000030620.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.533.10	UniProtKB/TrEMBL
InterPro	DEATH-like_dom_sf	UniProtKB/TrEMBL
	Death_domain	UniProtKB/TrEMBL
	DED_dom	UniProtKB/TrEMBL
	FADD	UniProtKB/TrEMBL
	FADD_vert	UniProtKB/TrEMBL
NCBI Gene	Fadd	ENTREZGENE
PANTHER	FAS-ASSOCIATED DEATH DOMAIN PROTEIN	UniProtKB/TrEMBL
	PTHR15077	UniProtKB/TrEMBL
Pfam	Death	UniProtKB/TrEMBL
	DED	UniProtKB/TrEMBL
PIRSF	FADD	UniProtKB/TrEMBL
PROSITE	DEATH_DOMAIN	UniProtKB/TrEMBL
	DED	UniProtKB/TrEMBL
SMART	DEATH	UniProtKB/TrEMBL
	DED	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47986	UniProtKB/TrEMBL
UniProt	A0A287CTM4	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)