Srf (serum response factor) - Rat Genome Database

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Gene: Srf (serum response factor) Ictidomys tridecemlineatus
Analyze
Symbol: Srf
Name: serum response factor
RGD ID: 12440067
Description: ENCODES a protein that exhibits chromatin binding (ortholog); chromatin DNA binding (ortholog); DNA binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); actin filament organization (ortholog); associative learning (ortholog); PARTICIPATES IN platelet-derived growth factor signaling pathway; ASSOCIATED WITH Cardiomegaly (ortholog); cardiomyopathy (ortholog); Cardiovascular Abnormalities (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOW QUALITY PROTEIN: serum response factor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494647,170,709 - 47,180,262 (+)NCBI
SpeTri2.0NW_00493647616,779,941 - 16,789,499 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin cytoskeleton organization  (ISO)
actin filament organization  (ISO)
associative learning  (ISO)
bicellular tight junction assembly  (ISO)
branching involved in blood vessel morphogenesis  (ISO)
bronchus cartilage development  (ISO)
cardiac myofibril assembly  (ISO)
cardiac vascular smooth muscle cell differentiation  (ISO)
cell migration involved in sprouting angiogenesis  (ISO)
cell-cell adhesion  (ISO)
cell-matrix adhesion  (ISO)
cellular response to glucose stimulus  (ISO)
cellular senescence  (ISO)
contractile actin filament bundle assembly  (ISO)
developmental growth  (ISO)
dorsal aorta morphogenesis  (ISO)
epithelial cell-cell adhesion  (ISO)
epithelial structure maintenance  (ISO)
erythrocyte development  (ISO)
eyelid development in camera-type eye  (ISO)
face development  (ISO)
forebrain development  (ISO)
gastrulation  (ISO)
heart development  (ISO)
heart looping  (ISO)
heart trabecula formation  (ISO)
hematopoietic stem cell differentiation  (ISO)
hippocampus development  (ISO)
in utero embryonic development  (ISO)
leukocyte differentiation  (ISO)
long-term memory  (ISO)
long-term synaptic depression  (ISO)
lung morphogenesis  (ISO)
lung smooth muscle development  (ISO)
megakaryocyte development  (ISO)
mesoderm formation  (ISO)
morphogenesis of an epithelial sheet  (ISO)
muscle cell cellular homeostasis  (ISO)
negative regulation of amyloid-beta clearance  (ISO)
negative regulation of cell migration  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of pri-miRNA transcription by RNA polymerase II  (ISO)
neuron migration  (ISO)
neuron projection development  (ISO)
platelet activation  (ISO)
platelet formation  (ISO)
positive regulation of axon extension  (ISO)
positive regulation of cell differentiation  (ISO)
positive regulation of DNA-binding transcription factor activity  (ISO)
positive regulation of filopodium assembly  (ISO)
positive regulation of pri-miRNA transcription by RNA polymerase II  (ISO)
positive regulation of smooth muscle contraction  (ISO)
positive regulation of transcription by glucose  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation  (ISO)
positive regulation of transcription initiation from RNA polymerase II promoter  (ISO)
positive regulation of transcription via serum response element binding  (ISO)
positive regulation of transcription, DNA-templated  (ISO)
positive thymic T cell selection  (ISO)
primitive streak formation  (ISO)
regulation of cell adhesion  (ISO)
regulation of transcription, DNA-templated  (ISO)
regulation of water loss via skin  (ISO)
response to cytokine  (ISO)
response to hormone  (ISO)
response to hypoxia  (ISO)
sarcomere organization  (ISO)
skin morphogenesis  (ISO)
stress fiber assembly  (ISO)
tangential migration from the subventricular zone to the olfactory bulb  (ISO)
thymus development  (ISO)
thyroid gland development  (ISO)
trachea cartilage development  (ISO)
trophectodermal cell differentiation  (ISO)

Cellular Component
chromatin  (ISO)
cytoplasm  (ISO)
nucleus  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Srf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494647,170,709 - 47,180,262 (+)NCBI
SpeTri2.0NW_00493647616,779,941 - 16,789,499 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SRF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl643,171,269 - 43,181,506 (+)EnsemblGRCh38hg38GRCh38
GRCh38643,171,269 - 43,181,506 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37643,139,007 - 43,149,244 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36643,246,898 - 43,257,222 (+)NCBINCBI36hg18NCBI36
Build 34643,247,014 - 43,257,221NCBI
Celera644,691,142 - 44,701,465 (+)NCBI
Cytogenetic Map6p21.1NCBI
HuRef642,855,575 - 42,865,934 (+)NCBIHuRef
CHM1_1643,141,808 - 43,152,132 (+)NCBICHM1_1
Srf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391746,857,764 - 46,869,194 (-)NCBIGRCm39mm39
GRCm39 Ensembl1746,859,255 - 46,867,101 (-)Ensembl
GRCm381746,546,838 - 46,558,267 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1746,548,329 - 46,556,175 (-)EnsemblGRCm38mm10GRCm38
MGSCv371746,683,788 - 46,693,111 (-)NCBIGRCm37mm9NCBIm37
MGSCv361746,010,028 - 46,019,351 (-)NCBImm8
Celera1749,982,837 - 49,992,041 (-)NCBICelera
Cytogenetic Map17CNCBI
Srf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2914,426,453 - 14,435,734 (+)NCBI
Rnor_6.0 Ensembl916,737,642 - 16,747,225 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0916,737,637 - 16,747,226 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0915,642,584 - 15,652,178 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.499,788,378 - 9,797,639 (+)NCBIRGSC3.4rn4RGSC3.4
Celera912,173,971 - 12,183,234 (+)NCBICelera
Cytogenetic Map9q12NCBI
Srf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554379,098,968 - 9,107,057 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554379,100,546 - 9,109,305 (+)NCBIChiLan1.0ChiLan1.0
SRF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1644,057,192 - 44,066,768 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl644,057,192 - 44,066,768 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0642,763,099 - 42,773,332 (+)NCBIMhudiblu_PPA_v0panPan3
SRF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11211,664,441 - 11,673,846 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1211,664,527 - 11,671,533 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1211,691,502 - 11,700,834 (+)NCBI
ROS_Cfam_1.01212,146,868 - 12,156,424 (+)NCBI
UMICH_Zoey_3.11211,674,421 - 11,683,753 (+)NCBI
UNSW_CanFamBas_1.01211,758,840 - 11,768,172 (+)NCBI
UU_Cfam_GSD_1.01211,853,634 - 11,862,966 (+)NCBI
SRF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl738,213,063 - 38,222,140 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1738,213,300 - 38,223,686 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2743,712,387 - 43,724,048 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SRF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11728,983,161 - 28,993,465 (-)NCBI
ChlSab1.1 Ensembl1728,983,002 - 28,992,995 (-)Ensembl
Vero_WHO_p1.0NW_02366604443,231,123 - 43,241,353 (+)NCBI
Srf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475416,371,995 - 16,381,287 (-)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_013355814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_013355814   ⟹   XP_013211268
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494647,170,709 - 47,180,262 (+)NCBI
SpeTri2.0NW_00493647616,779,941 - 16,789,499 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013211268 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013211268   ⟸   XM_013355814
- Sequence:
Protein Domains
MADS-box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000014222 ENTREZGENE
Ensembl Protein ENSSTOP00000012736 ENTREZGENE
NCBI Gene Srf ENTREZGENE