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ONTOLOGY REPORT - ANNOTATIONS

Term:mitotic DNA integrity checkpoint signaling
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Accession:GO:0044774 term browser browse the term
Definition:A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during mitosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction.
Synonyms:exact_synonym: intracellular signal transduction involved in mitotic cell cycle G2/M transition decatenation checkpoint;   intracellular signal transduction involved in topo II checkpoint;   intracellular signal transduction pathway involved in mitotic DNA integrity checkpoint;   intracellular signaling cascade involved in mitotic DNA integrity checkpoint;   intracellular signaling cascade involved in mitotic cell cycle G2/M transition decatenation checkpoint;   intracellular signaling cascade involved in topo II checkpoint;   intracellular signaling chain involved in mitotic DNA integrity checkpoint;   intracellular signaling chain involved in mitotic cell cycle G2/M transition decatenation checkpoint;   intracellular signaling pathway involved in mitotic DNA integrity checkpoint;   mitotic DNA integrity checkpoint;   mitotic cell cycle G2/M transition decatenation checkpoint;   signal transduction involved in mitotic DNA integrity checkpoint
 narrow_synonym: intracellular signal transduction pathway involved in mitotic cell cycle G2/M transition decatenation checkpoint;   intracellular signal transduction pathway involved in topo II checkpoint;   intracellular signal transduction pathway involved in topoisomerase II checkpoint;   intracellular signaling pathway involved in topo II checkpoint
 related_synonym: intracellular signaling pathway involved in mitotic cell cycle G2/M transition decatenation checkpoint;   intracellular signaling pathway involved in topoisomerase II checkpoint;   signal transduction via intracellular signaling cascade involved in mitotic cell cycle G2/M transition decatenation checkpoint;   signal transduction via intracellular signaling cascade involved in topo II checkpoint
 alt_id: GO:0070683;   GO:1902403


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mitotic DNA integrity checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100986203 histone-lysine N-methyltransferase SETMAR involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:4,256,539...4,271,593
Ensembl chr 3:4,357,890...4,371,791 		JBrowse link
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP2 caspase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:135,283,072...135,307,855
Ensembl chr 7:147,773,749...147,792,958 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599 		JBrowse link
G CRADD CASP2 and RIPK1 domain containing adaptor with death domain involved_in ISO (PMID:21726810) UniProt PMID:21726810 NCBI chr12:91,220,813...91,593,799 JBrowse link
G E2F7 E2F transcription factor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:74,540,049...74,582,561
Ensembl chr12:77,388,950...77,433,262 		JBrowse link
G LOC100977427 large ribosomal subunit protein uL24 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:56,616,749...56,617,299
Ensembl chr17:48,009,198...48,015,977 		JBrowse link
G MDM2 MDM2 proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:66,322,340...66,357,010
Ensembl chr12:69,102,084...69,133,278 		JBrowse link
G MUC1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) BHF-UCL PMID:15710329 NCBI chr 1:130,533,508...130,537,866
Ensembl chr 1:134,141,969...134,145,850 		JBrowse link
G PCBP4 poly(rC) binding protein 4 involved_in ISO (PMID:10891498) UniProt PMID:10891498 NCBI chr 3:51,898,857...51,908,932
Ensembl chr 3:53,127,448...53,137,293 		JBrowse link
G PIDD1 p53-induced death domain protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:816,629...827,295
Ensembl chr11:860,899...867,436 		JBrowse link
G PML PML nuclear body scaffold involved_in ISO (PMID:15626733) UniProt PMID:15626733 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883 		JBrowse link
G PPP2R5C protein phosphatase 2 regulatory subunit B'gamma involved_in ISO (PMID:17245430) UniProt PMID:17245430 NCBI chr14:82,383,086...82,549,822
Ensembl chr14:102,206,396...102,372,978 		JBrowse link
G PRAP1 proline rich acidic protein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr10:134,248,728...134,268,442 JBrowse link
G RBM38 RNA binding motif protein 38 involved_in ISO (PMID:17050675) UniProt PMID:17050675 NCBI chr20:53,731,641...53,749,688 JBrowse link
G RPL26 ribosomal protein L26 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:43,274,839...43,282,606
Ensembl chr17:48,009,198...48,015,977 		JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16107883) Ensembl
MGI		 PMID:16107883 GO_REF:0000107 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120 		JBrowse link
mitotic DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC7 cell division cycle 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:94,158,628...94,183,537
Ensembl chr 1:92,902,631...92,927,203 		JBrowse link
G ZNF830 zinc finger protein 830 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23213458) Ensembl
TreeGrafter
MGI		 PMID:23213458 GO_REF:0000107 GO_REF:0000118 NCBI chr17:21,823,998...21,825,632
Ensembl chr17:22,116,304...22,117,482 		JBrowse link
mitotic DNA replication checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC6 cell division cycle 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:16,987,721...17,002,488
Ensembl chr17:17,211,681...17,225,972 		JBrowse link
G CLSPN claspin involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:34,991,082...35,040,515
Ensembl chr 1:36,182,726...36,218,544 		JBrowse link
G DONSON DNA replication fork stabilization factor DONSON involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:19,944,692...19,956,140
Ensembl chr21:33,317,841...33,328,132 		JBrowse link
G HUS1 HUS1 checkpoint clamp component involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:48,606,848...48,622,194
Ensembl chr 7:48,714,668...48,731,005 		JBrowse link
G HUS1B HUS1 checkpoint clamp component B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:466,508...469,590
Ensembl chr 6:601,288...602,124 		JBrowse link
G NAE1 NEDD8 activating enzyme E1 subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:47,119,548...47,147,679
Ensembl chr16:66,221,829...66,246,865 		JBrowse link
G ORC1 origin recognition complex subunit 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:51,630,344...51,666,327
Ensembl chr 1:53,238,377...53,273,653 		JBrowse link
G RAD17 RAD17 checkpoint clamp loader component involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:44,586,083...44,630,719
Ensembl chr 5:46,156,294...46,202,197 		JBrowse link
G TICRR TOPBP1 interacting checkpoint and replication regulator involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr15:68,270,029...68,322,201
Ensembl chr15:87,476,738...87,528,870 		JBrowse link
G TOPBP1 DNA topoisomerase II binding protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:130,667,998...130,729,569
Ensembl chr 3:138,143,893...138,203,363 		JBrowse link
G ZNF830 zinc finger protein 830 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:21,823,998...21,825,632
Ensembl chr17:22,116,304...22,117,482 		JBrowse link
mitotic G1 DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCND1 cyclin D1 involved_in ISO (PMID:19412162) UniProt PMID:19412162 NCBI chr11:64,737,006...64,750,353 JBrowse link
G DGKZ diacylglycerol kinase zeta involved_in ISO (PMID:16286473) UniProt PMID:16286473 NCBI chr11:46,291,592...46,339,127
Ensembl chr11:46,841,605...46,889,763 		JBrowse link
G FBXO31 F-box protein 31 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:67,997,481...68,053,081
Ensembl chr16:87,322,364...87,377,104 		JBrowse link
G GIGYF2 GRB10 interacting GYF protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19744960) Ensembl
MGI		 PMID:19744960 GO_REF:0000107 NCBI chr2B:119,929,004...120,090,367
Ensembl chr2B:238,847,674...239,007,549 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:44,201,391...44,386,803
Ensembl chr 8:41,593,029...41,778,299 		JBrowse link
G RFWD3 ring finger and WD repeat domain 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:55,187,178...55,233,265
Ensembl chr16:74,541,450...74,586,951 		JBrowse link
G RPA2 replication protein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:27,151,784...27,175,110
Ensembl chr 1:28,191,731...28,214,666 		JBrowse link
G RPS27L ribosomal protein S27 like involved_in ISO (PMID:18056458) UniProt PMID:18056458 NCBI chr15:42,101,137...42,105,019
Ensembl chr15:60,397,131...60,400,643 		JBrowse link
G SDE2 SDE2 telomere maintenance homolog involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:201,443,945...201,460,668
Ensembl chr 1:206,441,517...206,457,679 		JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16107883) Ensembl
MGI		 PMID:16107883 GO_REF:0000107 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120 		JBrowse link
G TREX1 three prime repair exonuclease 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23993650)
(PMID:18045533)		 Ensembl
MGI		 PMID:18045533 PMID:23993650 GO_REF:0000107 NCBI chr 3:48,387,762...48,389,693
Ensembl chr 3:49,470,222...49,471,331 		JBrowse link
G WAC WW domain containing adaptor with coiled-coil involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:28,685,294...28,777,176
Ensembl chr10:29,042,331...29,130,591 		JBrowse link
mitotic G2 DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABRAXAS1 abraxas 1, BRCA1 A complex subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:40,711,139...40,736,763
Ensembl chr 4:46,556,892...46,581,573 		JBrowse link
G ATM ATM serine/threonine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:103,109,979...103,256,405
Ensembl chr11:106,584,228...106,727,041 		JBrowse link
G BABAM1 BRISC and BRCA1 A complex member 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:16,755,518...16,767,634
Ensembl chr19:17,729,568...17,742,447 		JBrowse link
G BABAM2 BRISC and BRCA1 A complex member 2 involved_in IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chr2A:27,884,907...28,338,302
Ensembl chr2A:27,974,917...28,420,519 		JBrowse link
G BLM BLM RecQ like helicase involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:69,407,248...69,508,070
Ensembl chr15:88,607,157...88,707,864 		JBrowse link
G BRCA1 BRCA1 DNA repair associated involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:14,197,946...14,279,064
Ensembl chr17:14,428,526...14,506,815 		JBrowse link
G BRCC3 BRCA1/BRCA2-containing complex subunit 3 involved_in IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107 NCBI chr  X:144,550,320...144,592,795
Ensembl chr  X:154,389,283...154,428,669 		JBrowse link
G BRSK1 BR serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:52,326,538...52,355,060
Ensembl chr19:61,021,493...61,045,659 		JBrowse link
G C8H10orf90 chromosome 8 C10orf90 homolog involved_in ISO (PMID:20154723) UniProt PMID:20154723 NCBI chr10:122,987,122...123,243,653
Ensembl chr10:127,259,451...127,357,119 		JBrowse link
G CCNG1 cyclin G1 ISO RGD PMID:9464250 RGD:2316029 NCBI chr 5:158,814,563...158,822,019
Ensembl chr 5:165,592,971...165,598,728 		JBrowse link
G CDC14B cell division cycle 14B involved_in ISO (PMID:18662541) UniProt PMID:18662541 NCBI chr 9:67,596,037...67,715,668 JBrowse link
G CDK1 cyclin dependent kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12937170) Ensembl
TreeGrafter
MGI		 PMID:12937170 GO_REF:0000107 GO_REF:0000118 NCBI chr10:57,314,692...57,331,261
Ensembl chr10:59,647,993...59,664,434 		JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:9,556,313...9,567,099
Ensembl chr17:9,738,141...9,749,302 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599 		JBrowse link
G CHEK1 checkpoint kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:120,446,352...120,478,207
Ensembl chr11:124,359,218...124,390,981 		JBrowse link
G CLSPN claspin involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:34,991,082...35,040,515
Ensembl chr 1:36,182,726...36,218,544 		JBrowse link
G CREB3L1 cAMP responsive element binding protein 3 like 1 involved_in ISO (PMID:37178686) UniProt PMID:37178686 NCBI chr11:46,236,384...46,280,145
Ensembl chr11:46,788,561...46,830,246 		JBrowse link
G DONSON DNA replication fork stabilization factor DONSON involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:19,944,692...19,956,140
Ensembl chr21:33,317,841...33,328,132 		JBrowse link
G DTL denticleless E3 ubiquitin protein ligase homolog involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:187,603,600...187,672,006
Ensembl chr 1:192,466,408...192,535,071 		JBrowse link
G FOXN3 forkhead box N3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:69,778,191...70,238,813
Ensembl chr14:89,140,892...89,387,807 		JBrowse link
G FOXO4 forkhead box O4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12048180) Ensembl
MGI		 PMID:12048180 GO_REF:0000107 NCBI chr  X:60,364,466...60,372,147
Ensembl chr  X:70,422,504...70,429,971 		JBrowse link
G FZR1 fizzy and cell division cycle 20 related 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:2,533,172...2,564,301
Ensembl chr19:3,500,117...3,510,867 		JBrowse link
G IER3 immediate early response 3 acts_upstream_of_or_within ISO (PMID:20467439) MGI PMID:20467439 NCBI chr 6:30,488,162...30,489,784 JBrowse link
G MBD4 methyl-CpG binding domain 4, DNA glycosylase acts_upstream_of_or_within ISO (PMID:14614141) MGI PMID:14614141 NCBI chr 3:126,489,125...126,498,034
Ensembl chr 3:133,839,643...133,851,450 		JBrowse link
G MBTPS1 membrane bound transcription factor peptidase, site 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:64,719,971...64,783,119
Ensembl chr16:84,063,508...84,126,000 		JBrowse link
G MBTPS2 membrane bound transcription factor peptidase, site 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:14,470,268...14,529,854
Ensembl chr  X:21,825,780...21,883,550 		JBrowse link
G MRE11 MRE11 homolog, double strand break repair nuclease acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:14690604) MGI
TreeGrafter		 PMID:14690604 GO_REF:0000118 NCBI chr11:89,418,537...89,500,705
Ensembl chr11:92,918,549...92,985,966 		JBrowse link
G MRNIP MRN complex interacting protein involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:174,989,967...175,020,550
Ensembl chr 5:182,299,016...182,340,632 		JBrowse link
G NBN nibrin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18614044) Ensembl
TreeGrafter
MGI
InterPro		 PMID:18614044 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:86,622,797...86,674,202
Ensembl chr 8:88,575,198...88,626,307 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:21741933) UniProt PMID:21741933 NCBI chr19:44,739,739...44,751,303 JBrowse link
G PLK1 polo like kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:14,420,972...14,432,821
Ensembl chr16:23,928,773...23,940,779 		JBrowse link
G RINT1 RAD50 interactor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:97,522,208...97,567,897
Ensembl chr 7:110,252,776...110,287,702 		JBrowse link
G SYF2 SYF2 pre-mRNA splicing factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22448250) Ensembl
MGI		 PMID:22448250 GO_REF:0000107 NCBI chr 1:24,422,931...24,432,870
Ensembl chr 1:25,397,241...25,406,806 		JBrowse link
G TAOK1 TAO kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:27,222,725...27,385,713
Ensembl chr17:27,746,797...27,840,623 		JBrowse link
G TAOK2 TAO kinase 2 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:30,347,229...30,366,743 JBrowse link
G TAOK3 TAO kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:115,730,619...115,954,149
Ensembl chr12:119,109,642...119,226,502 		JBrowse link
G TICRR TOPBP1 interacting checkpoint and replication regulator involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:68,270,029...68,322,201
Ensembl chr15:87,476,738...87,528,870 		JBrowse link
G TOPBP1 DNA topoisomerase II binding protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:130,667,998...130,729,569
Ensembl chr 3:138,143,893...138,203,363 		JBrowse link
G TRIM39 tripartite motif containing 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:30,104,381...30,121,649
Ensembl chr 6:30,975,260...30,995,764 		JBrowse link
G UIMC1 ubiquitin interaction motif containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:172,205,958...172,321,758
Ensembl chr 5:179,271,577...179,374,229 		JBrowse link
mitotic intra-S DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF2 activating transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:62,348,245...62,444,428
Ensembl chr2B:179,799,365...179,895,007 		JBrowse link
G CHEK2 checkpoint kinase 2 involved_in ISO (PMID:11298456) UniProt PMID:11298456 NCBI chr22:9,757,038...9,811,171 JBrowse link
G EME1 essential meiotic structure-specific endonuclease 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:44,467,537...44,475,883
Ensembl chr17:49,341,791...49,349,959 		JBrowse link
G EME2 essential meiotic structure-specific endonuclease subunit 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:395,571...403,233
Ensembl chr16:1,825,622...1,829,557 		JBrowse link
G FANCD2 FA complementation group D2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:9,932,292...10,037,332
Ensembl chr 3:10,312,476...10,389,190 		JBrowse link
G HUS1 HUS1 checkpoint clamp component involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:48,606,848...48,622,194
Ensembl chr 7:48,714,668...48,731,005 		JBrowse link
G HUS1B HUS1 checkpoint clamp component B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:466,508...469,590
Ensembl chr 6:601,288...602,124 		JBrowse link
G MRE11 MRE11 homolog, double strand break repair nuclease acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:14690604), (PMID:18614044) MGI
TreeGrafter		 PMID:14690604 PMID:18614044 GO_REF:0000118 NCBI chr11:89,418,537...89,500,705
Ensembl chr11:92,918,549...92,985,966 		JBrowse link
G MSH2 mutS homolog 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15533840) Ensembl
MGI		 PMID:15533840 GO_REF:0000107 NCBI chr2A:47,524,468...47,602,376
Ensembl chr2A:48,447,207...48,554,461 		JBrowse link
G MUS81 MUS81 structure-specific endonuclease subunit involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:61,220,699...61,226,747
Ensembl chr11:64,549,840...64,555,875 		JBrowse link
G NEK11 NIMA related kinase 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:128,111,202...128,434,781
Ensembl chr 3:135,433,828...135,757,221 		JBrowse link
G RAD17 RAD17 checkpoint clamp loader component involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:44,586,083...44,630,719
Ensembl chr 5:46,156,294...46,202,197 		JBrowse link
G RAD9A RAD9 checkpoint clamp component A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9766521) Ensembl
TreeGrafter
MGI		 PMID:9766521 GO_REF:0000107 GO_REF:0000118 NCBI chr11:62,675,480...62,756,886
Ensembl chr11:66,061,208...66,068,214 		JBrowse link
G RAD9B RAD9 checkpoint clamp component B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:108,072,061...108,103,338
Ensembl chr12:111,467,845...111,498,350 		JBrowse link
G TIPIN TIMELESS interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:45,290,350...45,310,335
Ensembl chr15:63,566,463...63,585,717 		JBrowse link
G XPC XPC complex subunit, DNA damage recognition and repair factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15533840) Ensembl
MGI		 PMID:15533840 GO_REF:0000107 NCBI chr 3:14,063,499...14,097,023
Ensembl chr 3:14,403,958...14,437,377 		JBrowse link
negative regulation of mitotic DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPP1R10 protein phosphatase 1 regulatory subunit 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:30,342,669...30,359,644
Ensembl chr 6:31,212,522...31,229,697 		JBrowse link
positive regulation of mitotic DNA damage checkpoint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAP3K20 mitogen-activated protein kinase kinase kinase 20 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:60,362,635...60,555,445
Ensembl chr2B:177,818,344...178,010,556 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16644
    cellular process 16207
      cell cycle process 1248
        mitotic cell cycle process 719
          mitotic cell cycle checkpoint signaling 138
            mitotic DNA integrity checkpoint signaling 88
              mitotic DNA damage checkpoint signaling + 84
              mitotic DNA replication checkpoint signaling 11
Path 2
Term Annotations click to browse term
  biological_process 16644
    biological regulation 11629
      regulation of biological process 11252
        regulation of cellular process 10895
          regulation of cell cycle 1037
            regulation of cell cycle process 719
              regulation of cell cycle phase transition 401
                negative regulation of cell cycle phase transition 246
                  cell cycle checkpoint signaling 180
                    DNA integrity checkpoint signaling 129
                      mitotic DNA integrity checkpoint signaling 88
                        mitotic DNA damage checkpoint signaling + 84
                        mitotic DNA replication checkpoint signaling 11
paths to the root