RAD9A (RAD9 checkpoint clamp component A) - Rat Genome Database

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Gene: RAD9A (RAD9 checkpoint clamp component A) Pan paniscus
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Symbol: RAD9A
Name: RAD9 checkpoint clamp component A
RGD ID: 11855988
Description: ENCODES a protein that exhibits 3'-5' exonuclease activity (inferred); enzyme binding (inferred); histone deacetylase binding (inferred); INVOLVED IN intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); mitotic intra-S DNA damage checkpoint signaling (ortholog); positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); ASSOCIATED WITH Aicardi-Goutieres Syndrome 3 (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN checkpoint clamp complex (inferred); cytoplasm (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cell cycle checkpoint control protein RAD9A; RAD9 homolog A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2968,543,353 - 68,625,399 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11169,587,473 - 69,667,974 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01162,675,480 - 62,756,886 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11165,989,692 - 66,068,220 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1166,061,208 - 66,068,214 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RAD9A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2968,543,353 - 68,625,399 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11169,587,473 - 69,667,974 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01162,675,480 - 62,756,886 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11165,989,692 - 66,068,220 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1166,061,208 - 66,068,214 (+)Ensemblpanpan1.1panPan2
RAD9A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381167,391,986 - 67,398,412 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1167,317,871 - 67,398,410 (+)EnsemblGRCh38hg38GRCh38
GRCh371167,159,457 - 67,165,883 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361166,915,999 - 66,922,459 (+)NCBINCBI36Build 36hg18NCBI36
Build 341166,915,998 - 66,922,458NCBI
Celera1164,492,609 - 64,499,069 (+)NCBICelera
Cytogenetic Map11q13.2NCBI
HuRef1163,487,804 - 63,494,266 (+)NCBIHuRef
CHM1_11167,042,459 - 67,048,919 (+)NCBICHM1_1
T2T-CHM13v2.01167,386,101 - 67,392,527 (+)NCBIT2T-CHM13v2.0
Rad9a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39194,245,195 - 4,251,710 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl194,245,195 - 4,251,661 (-)EnsemblGRCm39 Ensembl
GRCm38194,195,196 - 4,201,672 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl194,195,196 - 4,201,662 (-)EnsemblGRCm38mm10GRCm38
MGSCv37194,195,198 - 4,201,603 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36194,195,198 - 4,201,603 (-)NCBIMGSCv36mm8
Celera194,066,339 - 4,072,744 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map193.89NCBI
Rad9a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81210,917,970 - 210,983,038 (-)NCBIGRCr8
mRatBN7.21201,488,511 - 201,553,582 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1201,487,136 - 201,553,608 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01219,443,347 - 219,450,574 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,444,092 - 219,450,451 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01226,313,998 - 226,321,213 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41206,778,534 - 206,785,230 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1199,032,877 - 199,040,104 (-)NCBICelera
Cytogenetic Map1q43NCBI
Rad9a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542218,079,652 - 18,085,548 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542218,079,634 - 18,146,122 (-)NCBIChiLan1.0ChiLan1.0
RAD9A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11850,065,154 - 50,070,582 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1850,065,685 - 50,070,710 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1848,675,558 - 48,681,255 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01850,987,052 - 50,992,749 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11850,200,399 - 50,206,093 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01849,775,106 - 49,780,803 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01850,569,398 - 50,575,099 (-)NCBIUU_Cfam_GSD_1.0
Rad9a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049475,905,921 - 5,911,611 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365992,345,646 - 2,354,029 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365992,348,869 - 2,353,907 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAD9A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl25,123,134 - 5,129,703 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.125,123,142 - 5,129,740 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.223,841,698 - 3,848,259 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RAD9A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.116,865,990 - 6,945,179 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl16,866,840 - 6,941,486 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038104,151,098 - 104,232,417 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rad9a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476719,124,517 - 19,176,231 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476719,123,710 - 19,180,505 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000038471   ⟹   ENSPPAP00000015780
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1166,061,208 - 66,068,214 (+)Ensembl
RefSeq Acc Id: XM_003828717   ⟹   XP_003828765
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2968,609,772 - 68,625,399 (+)NCBI
NHGRI_mPanPan11169,654,930 - 69,667,974 (+)NCBI
Mhudiblu_PPA_v01162,743,770 - 62,756,886 (+)NCBI
PanPan1.11166,061,209 - 66,068,220 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008954156   ⟹   XP_008952404
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2968,619,141 - 68,625,399 (+)NCBI
NHGRI_mPanPan11169,661,716 - 69,667,974 (+)NCBI
Mhudiblu_PPA_v01162,750,719 - 62,756,886 (+)NCBI
PanPan1.11166,062,078 - 66,068,220 (+)NCBI
Sequence:
RefSeq Acc Id: XM_014346867   ⟹   XP_014202353
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2968,543,353 - 68,625,399 (+)NCBI
NHGRI_mPanPan11169,587,473 - 69,667,974 (+)NCBI
Mhudiblu_PPA_v01162,675,485 - 62,756,886 (+)NCBI
PanPan1.11165,989,692 - 66,068,220 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024930677   ⟹   XP_024786445
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2968,543,353 - 68,625,399 (+)NCBI
NHGRI_mPanPan11169,587,473 - 69,667,974 (+)NCBI
Mhudiblu_PPA_v01162,675,480 - 62,756,886 (+)NCBI
PanPan1.11165,989,692 - 66,068,220 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034933148   ⟹   XP_034789039
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2968,619,234 - 68,625,399 (+)NCBI
NHGRI_mPanPan11169,661,806 - 69,667,974 (+)NCBI
Mhudiblu_PPA_v01162,750,716 - 62,756,886 (+)NCBI
RefSeq Acc Id: XM_034933150   ⟹   XP_034789041
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2968,543,353 - 68,625,399 (+)NCBI
NHGRI_mPanPan11169,587,473 - 69,667,974 (+)NCBI
Mhudiblu_PPA_v01162,675,486 - 62,756,886 (+)NCBI
RefSeq Acc Id: XM_063608609   ⟹   XP_063464679
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2968,543,449 - 68,625,399 (+)NCBI
RefSeq Acc Id: XP_014202353   ⟸   XM_014346867
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AJH6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003828765   ⟸   XM_003828717
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AJH6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008952404   ⟸   XM_008954156
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AJH6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024786445   ⟸   XM_024930677
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AJH6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034789041   ⟸   XM_034933150
- Peptide Label: isoform X5
- UniProtKB: A0A2R9AJH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034789039   ⟸   XM_034933148
- Peptide Label: isoform X4
RefSeq Acc Id: ENSPPAP00000015780   ⟸   ENSPPAT00000038471
RefSeq Acc Id: XP_063464679   ⟸   XM_063608609
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031016 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000038471.1 UniProtKB/TrEMBL
Gene3D-CATH 3.70.10.10 UniProtKB/TrEMBL
InterPro DNA_clamp_sf UniProtKB/TrEMBL
  Rad9 UniProtKB/TrEMBL
  Rad9/Ddc1 UniProtKB/TrEMBL
KEGG Report pps:100984970 UniProtKB/TrEMBL
NCBI Gene RAD9A ENTREZGENE
PANTHER CELL CYCLE CHECKPOINT CONTROL PROTEIN RAD9A UniProtKB/TrEMBL
  PTHR15237 UniProtKB/TrEMBL
Pfam Rad9 UniProtKB/TrEMBL
PIRSF Cell_cycle_RAD9 UniProtKB/TrEMBL
Superfamily-SCOP DNA clamp UniProtKB/TrEMBL
UniProt A0A2R9AJH6 ENTREZGENE, UniProtKB/TrEMBL