CHEK1 (checkpoint kinase 1) - Rat Genome Database

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Gene: CHEK1 (checkpoint kinase 1) Pan paniscus
Analyze
Symbol: CHEK1
Name: checkpoint kinase 1
RGD ID: 11957312
Description: ENCODES a protein that exhibits protein kinase activity (ortholog); INVOLVED IN apoptotic process involved in development (ortholog); cellular response to caffeine (ortholog); cellular response to DNA damage stimulus (ortholog); PARTICIPATES IN G2/M DNA damage checkpoint pathway; p53 signaling pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Chromosome 11, Partial Trisomy 11q (ortholog); Dwarfism (ortholog); FOUND IN chromosome, telomeric region (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein kinase Chk1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.111124,359,218 - 124,410,385 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11124,359,218 - 124,390,981 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v011120,446,352 - 120,478,207 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
CHEK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.111124,359,218 - 124,410,385 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11124,359,218 - 124,390,981 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v011120,446,352 - 120,478,207 (+)NCBIMhudiblu_PPA_v0panPan3
CHEK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811125,625,136 - 125,681,124 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl11125,625,163 - 125,676,255 (+)EnsemblGRCh38hg38GRCh38
GRCh3711125,495,031 - 125,546,150 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611125,001,547 - 125,030,847 (+)NCBINCBI36hg18NCBI36
Build 3411125,001,546 - 125,030,847NCBI
Celera11122,655,346 - 122,706,400 (+)NCBI
Cytogenetic Map11q24.2NCBI
HuRef11121,436,397 - 121,487,529 (+)NCBIHuRef
CHM1_111125,381,155 - 125,432,283 (+)NCBICHM1_1
Chek1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39936,619,778 - 36,637,954 (-)NCBIGRCm39mm39
GRCm39 Ensembl936,619,778 - 36,638,361 (-)Ensembl
GRCm38936,708,482 - 36,726,658 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl936,708,482 - 36,727,065 (-)EnsemblGRCm38mm10GRCm38
MGSCv37936,516,067 - 36,534,243 (-)NCBIGRCm37mm9NCBIm37
MGSCv36936,458,153 - 36,476,298 (-)NCBImm8
Celera933,911,337 - 33,929,618 (-)NCBICelera
Cytogenetic Map9A4NCBI
Chek1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2836,420,565 - 36,443,477 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl836,420,569 - 36,441,009 (-)Ensembl
Rnor_6.0839,181,162 - 39,201,588 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl839,181,163 - 39,243,882 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0839,184,020 - 39,204,446 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4837,954,322 - 37,974,748 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1837,963,088 - 37,983,514 (-)NCBI
Celera838,000,251 - 38,020,582 (+)NCBICelera
Cytogenetic Map8q21NCBI
Chek1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541226,627,606 - 26,650,554 (+)NCBIChiLan1.0ChiLan1.0
CHEK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.158,878,511 - 8,910,626 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl58,879,147 - 8,907,669 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha58,923,479 - 8,955,720 (-)NCBI
ROS_Cfam_1.058,821,650 - 8,853,260 (-)NCBI
ROS_Cfam_1.0 Ensembl58,821,983 - 8,853,208 (-)Ensembl
UMICH_Zoey_3.158,890,756 - 8,922,634 (-)NCBI
UNSW_CanFamBas_1.058,860,679 - 8,892,710 (-)NCBI
UU_Cfam_GSD_1.058,897,288 - 8,929,731 (-)NCBI
Chek1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947107,757,062 - 107,779,783 (+)NCBI
SpeTri2.0NW_0049367432,004,535 - 2,027,287 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHEK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl952,726,885 - 52,790,706 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1952,759,224 - 52,790,878 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2958,411,395 - 58,444,086 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CHEK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11116,768,141 - 116,809,557 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1116,767,944 - 116,801,371 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660439,201,283 - 9,302,468 (-)NCBIVero_WHO_p1.0
Chek1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249271,609,404 - 1,643,409 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000022876   ⟹   ENSPPAP00000004995
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11124,359,218 - 124,390,981 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000022888   ⟹   ENSPPAP00000004996
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11124,361,009 - 124,389,151 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000022890   ⟹   ENSPPAP00000004998
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11124,361,009 - 124,389,151 (+)Ensembl
RefSeq Acc Id: XM_003819914   ⟹   XP_003819962
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.111124,360,469 - 124,390,981 (+)NCBI
Mhudiblu_PPA_v011120,447,655 - 120,478,207 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003819915   ⟹   XP_003819963
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.111124,360,559 - 124,390,981 (+)NCBI
Mhudiblu_PPA_v011120,447,723 - 120,478,207 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008973329   ⟹   XP_008971577
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.111124,359,218 - 124,390,981 (+)NCBI
Mhudiblu_PPA_v011120,446,352 - 120,478,207 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008973330   ⟹   XP_008971578
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.111124,360,558 - 124,390,972 (+)NCBI
Mhudiblu_PPA_v011120,447,723 - 120,478,207 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003819962 (Get FASTA)   NCBI Sequence Viewer  
  XP_003819963 (Get FASTA)   NCBI Sequence Viewer  
  XP_008971577 (Get FASTA)   NCBI Sequence Viewer  
  XP_008971578 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_008971577   ⟸   XM_008973329
- Sequence:
RefSeq Acc Id: XP_003819962   ⟸   XM_003819914
- Sequence:
RefSeq Acc Id: XP_003819963   ⟸   XM_003819915
- Sequence:
RefSeq Acc Id: XP_008971578   ⟸   XM_008973330
- Sequence:
RefSeq Acc Id: ENSPPAP00000004995   ⟸   ENSPPAT00000022876
RefSeq Acc Id: ENSPPAP00000004998   ⟸   ENSPPAT00000022890
RefSeq Acc Id: ENSPPAP00000004996   ⟸   ENSPPAT00000022888
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000020777 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000004995 ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAP00000004996 UniProtKB/TrEMBL
  ENSPPAP00000004998 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000022876 UniProtKB/TrEMBL
  ENSPPAT00000022888 UniProtKB/TrEMBL
  ENSPPAT00000022890 UniProtKB/TrEMBL
InterPro Chk1_catalytic_dom UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
KEGG Report pps:100982317 UniProtKB/TrEMBL
NCBI Gene CHEK1 ENTREZGENE
Pfam Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A2R8ZJ32_PANPA UniProtKB/TrEMBL
  A0A2R8ZM27_PANPA UniProtKB/TrEMBL
  A0A2R8ZQA7_PANPA UniProtKB/TrEMBL