TAOK2 (TAO kinase 2) - Rat Genome Database

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Gene: TAOK2 (TAO kinase 2) Pan paniscus
Analyze
Symbol: TAOK2
Name: TAO kinase 2
RGD ID: 11785610
Description: ENCODES a protein that exhibits ATP binding (ortholog); MAP kinase kinase kinase activity (ortholog); INVOLVED IN MAPK cascade (ortholog); regulation of postsynapse organization (ortholog); regulation of synaptic membrane adhesion (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); chromosome 16p11.2 deletion syndrome, 593-kb (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein kinase TAO2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21830,723,431 - 30,742,044 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11635,483,871 - 35,502,484 (-)NCBINHGRI_mPanPan1
PanPan1.11630,347,229 - 30,365,647 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1630,347,229 - 30,366,743 (+)Ensemblpanpan1.1panPan2


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TAOK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21830,723,431 - 30,742,044 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11635,483,871 - 35,502,484 (-)NCBINHGRI_mPanPan1
PanPan1.11630,347,229 - 30,365,647 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1630,347,229 - 30,366,743 (+)Ensemblpanpan1.1panPan2
TAOK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381629,973,868 - 29,992,261 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1629,973,868 - 29,992,261 (+)EnsemblGRCh38hg38GRCh38
GRCh371629,985,189 - 30,003,582 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361629,892,723 - 29,911,082 (+)NCBINCBI36Build 36hg18NCBI36
Build 341629,892,722 - 29,907,220NCBI
Celera1672,792,142 - 72,810,504 (-)NCBICelera
Cytogenetic Map16p11.2NCBI
HuRef1627,646,198 - 27,664,595 (+)NCBIHuRef
CHM1_11631,200,977 - 31,219,371 (+)NCBICHM1_1
T2T-CHM13v2.01630,256,503 - 30,274,899 (+)NCBIT2T-CHM13v2.0
Taok2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397126,464,848 - 126,485,468 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7126,464,850 - 126,483,875 (-)EnsemblGRCm39 Ensembl
GRCm387126,865,674 - 126,886,296 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7126,865,678 - 126,884,703 (-)EnsemblGRCm38mm10GRCm38
MGSCv377134,009,191 - 134,028,481 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera7126,713,815 - 126,733,105 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.25NCBI
Taok2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81190,906,236 - 190,925,359 (-)NCBIGRCr8
mRatBN7.21181,475,708 - 181,494,738 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1181,475,711 - 181,494,613 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1189,830,945 - 189,845,358 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01197,017,020 - 197,031,433 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01189,684,241 - 189,698,650 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01198,301,789 - 198,354,601 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,301,938 - 198,320,075 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01205,281,965 - 205,302,445 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41186,049,010 - 186,063,423 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11186,198,900 - 186,213,304 (-)NCBI
Celera1179,134,902 - 179,149,315 (-)NCBICelera
Cytogenetic Map1q36NCBI
Taok2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554936,969,096 - 6,985,878 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554936,968,537 - 6,986,608 (-)NCBIChiLan1.0ChiLan1.0
TAOK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1618,014,685 - 18,029,188 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl618,000,138 - 18,029,185 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha619,587,820 - 19,606,168 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0618,144,778 - 18,163,340 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl618,092,584 - 18,163,339 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1617,944,193 - 17,962,549 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0617,859,369 - 17,877,699 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0618,175,174 - 18,193,525 (+)NCBIUU_Cfam_GSD_1.0
Taok2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344124,379,172 - 124,397,455 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650112,477,032 - 12,495,501 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650112,477,032 - 12,495,298 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAOK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl318,177,737 - 18,198,085 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1318,178,347 - 18,198,092 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TAOK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1526,669,687 - 26,688,418 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl526,669,702 - 26,688,389 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660682,844,898 - 2,863,744 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Taok2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478213,256,085 - 13,262,626 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla_female_1.0 EnsemblNW_00462478213,234,422 - 13,252,663 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478213,234,422 - 13,263,495 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000057041   ⟹   ENSPPAP00000034160
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1630,347,229 - 30,361,794 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000057055   ⟹   ENSPPAP00000034174
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1630,351,108 - 30,366,743 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000057069   ⟹   ENSPPAP00000034188
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1630,351,143 - 30,361,370 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000057070   ⟹   ENSPPAP00000034189
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1630,351,143 - 30,361,370 (+)Ensembl
RefSeq Acc Id: XM_003809348   ⟹   XP_003809396
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21830,723,606 - 30,742,044 (+)NCBI
NHGRI_mPanPan11635,483,871 - 35,502,290 (-)NCBI
PanPan1.11630,347,231 - 30,365,647 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008961588   ⟹   XP_008959836
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21830,723,431 - 30,738,177 (+)NCBI
NHGRI_mPanPan11635,487,723 - 35,502,484 (-)NCBI
PanPan1.11630,347,229 - 30,361,794 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003809396 (Get FASTA)   NCBI Sequence Viewer  
  XP_008959836 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000034160.1
  ENSPPAP00000034174
  ENSPPAP00000034174.1
  ENSPPAP00000034188.1
  ENSPPAP00000034189.1
RefSeq Acc Id: XP_008959836   ⟸   XM_008961588
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_003809396   ⟸   XM_003809348
- Peptide Label: isoform X2
- UniProtKB: A0A2R9C6L1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000034160   ⟸   ENSPPAT00000057041
Ensembl Acc Id: ENSPPAP00000034174   ⟸   ENSPPAT00000057055
Ensembl Acc Id: ENSPPAP00000034188   ⟸   ENSPPAT00000057069
Ensembl Acc Id: ENSPPAP00000034189   ⟸   ENSPPAT00000057070
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000039887 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057041.1 UniProtKB/TrEMBL
  ENSPPAT00000057055.1 UniProtKB/TrEMBL
  ENSPPAT00000057069.1 UniProtKB/TrEMBL
  ENSPPAT00000057070.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
  TAO_STE20_kinase UniProtKB/TrEMBL
NCBI Gene TAOK2 ENTREZGENE
PANTHER SERINE/THREONINE-PROTEIN KINASE TAO1-LIKE PROTEIN UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE TAO2 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A2R9BWX8_PANPA UniProtKB/TrEMBL
  A0A2R9C086_PANPA UniProtKB/TrEMBL
  A0A2R9C6L1 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C6N2_PANPA UniProtKB/TrEMBL