LOC100986203 (histone-lysine N-methyltransferase SETMAR) - Rat Genome Database

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Gene: LOC100986203 (histone-lysine N-methyltransferase SETMAR) Pan paniscus
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Symbol: LOC100986203 (Ensembl: SETMAR)
Name: histone-lysine N-methyltransferase SETMAR (Ensembl:SET domain and mariner transposase fusion gene)
RGD ID: 11890450
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA topoisomerase binding (inferred); double-stranded DNA binding (inferred); INVOLVED IN positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity (ortholog); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); spinocerebellar ataxia type 15 (ortholog); FOUND IN chromosome (inferred); condensed chromosome (inferred); nucleolus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SET domain and mariner transposase fusion; SETMAR
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v224,314,856 - 4,328,889 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan134,318,118 - 4,333,649 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v034,256,539 - 4,271,593 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.134,357,779 - 4,371,810 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl34,357,890 - 4,371,791 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC100986203
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v224,314,856 - 4,328,889 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan134,318,118 - 4,333,649 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v034,256,539 - 4,271,593 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.134,357,779 - 4,371,810 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl34,357,890 - 4,371,791 (+)Ensemblpanpan1.1panPan2
SETMAR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3834,303,369 - 4,317,265 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl34,303,332 - 4,317,265 (+)EnsemblGRCh38hg38GRCh38
GRCh3734,345,053 - 4,358,949 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3634,320,016 - 4,333,949 (+)NCBINCBI36Build 36hg18NCBI36
Build 3434,320,070 - 4,333,948NCBI
Celera34,282,941 - 4,296,902 (+)NCBICelera
Cytogenetic Map3p26.1NCBI
HuRef34,278,470 - 4,292,431 (+)NCBIHuRef
CHM1_134,295,088 - 4,309,040 (+)NCBICHM1_1
T2T-CHM13v2.034,297,118 - 4,311,014 (+)NCBIT2T-CHM13v2.0
Setmar
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396108,042,006 - 108,054,088 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6108,042,006 - 108,054,083 (+)EnsemblGRCm39 Ensembl
GRCm386108,065,045 - 108,077,127 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6108,065,045 - 108,077,122 (+)EnsemblGRCm38mm10GRCm38
MGSCv376108,015,040 - 108,027,114 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366108,030,822 - 108,042,902 (+)NCBIMGSCv36mm8
Celera6109,874,089 - 109,886,144 (+)NCBICelera
Cytogenetic Map6E1NCBI
cM Map649.71NCBI
Setmar
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84142,602,066 - 142,614,208 (+)NCBIGRCr8
mRatBN7.24141,046,058 - 141,058,183 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4141,046,069 - 141,058,197 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4146,462,703 - 146,474,799 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04142,243,420 - 142,255,522 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04140,887,379 - 140,899,484 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04140,092,346 - 140,104,495 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4140,092,352 - 140,105,316 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04204,560,058 - 204,571,718 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44143,564,021 - 143,576,022 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4129,699,443 - 129,711,306 (+)NCBICelera
Cytogenetic Map4q41NCBI
LOC102020128
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554219,066,906 - 9,080,352 (-)NCBIChiLan1.0ChiLan1.0
SETMAR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12013,214,241 - 13,224,020 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2013,214,241 - 13,224,020 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2013,187,342 - 13,197,119 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02013,252,140 - 13,261,903 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2013,249,713 - 13,261,957 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12012,956,313 - 12,966,091 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02013,296,532 - 13,306,290 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02013,283,976 - 13,293,754 (-)NCBIUU_Cfam_GSD_1.0
LOC101962206
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494210,805,678 - 10,817,230 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365773,761,078 - 3,771,864 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100514009
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11360,914,412 - 60,933,064 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21367,224,808 - 67,234,390 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SETMAR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12240,389,390 - 40,403,917 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2240,389,485 - 40,403,898 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041126,264,839 - 126,279,998 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101704237
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477314,680,571 - 14,692,583 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000056869   ⟹   ENSPPAP00000033988
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl34,357,890 - 4,371,791 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000056874   ⟹   ENSPPAP00000033993
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl34,357,890 - 4,371,791 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000056882   ⟹   ENSPPAP00000034001
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl34,357,890 - 4,369,868 (+)Ensembl
RefSeq Acc Id: XM_003831222   ⟹   XP_003831270
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v224,314,856 - 4,328,889 (+)NCBI
NHGRI_mPanPan134,318,118 - 4,333,649 (+)NCBI
Mhudiblu_PPA_v034,256,539 - 4,271,593 (+)NCBI
PanPan1.134,357,779 - 4,371,810 (+)NCBI
Sequence:
RefSeq Acc Id: XM_057301594   ⟹   XP_057157577
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v224,314,897 - 4,328,889 (+)NCBI
NHGRI_mPanPan134,319,711 - 4,333,649 (+)NCBI
RefSeq Acc Id: XM_057301595   ⟹   XP_057157578
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v224,314,890 - 4,328,889 (+)NCBI
NHGRI_mPanPan134,318,118 - 4,333,649 (+)NCBI
RefSeq Acc Id: XM_063602091   ⟹   XP_063458161
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v224,314,866 - 4,328,889 (+)NCBI
RefSeq Acc Id: XP_003831270   ⟸   XM_003831222
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BWD0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000033988   ⟸   ENSPPAT00000056869
Ensembl Acc Id: ENSPPAP00000033993   ⟸   ENSPPAT00000056874
Ensembl Acc Id: ENSPPAP00000034001   ⟸   ENSPPAT00000056882
RefSeq Acc Id: XP_057157578   ⟸   XM_057301595
- Peptide Label: isoform X4
RefSeq Acc Id: XP_057157577   ⟸   XM_057301594
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063458161   ⟸   XM_063602091
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BWD5 (UniProtKB/TrEMBL)
Protein Domains
Post-SET   Pre-SET   SET


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000039860 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000056869.1 UniProtKB/TrEMBL
  ENSPPAT00000056874.1 UniProtKB/TrEMBL
  ENSPPAT00000056882.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  1.10.10.1450 UniProtKB/TrEMBL
  2.170.270.10 UniProtKB/TrEMBL
  3.30.420.10 UniProtKB/TrEMBL
InterPro H3K9_Histone-Lys_N-MTase UniProtKB/TrEMBL
  Mos1_HTH UniProtKB/TrEMBL
  Post-SET_dom UniProtKB/TrEMBL
  Pre-SET_dom UniProtKB/TrEMBL
  RNaseH_sf UniProtKB/TrEMBL
  SET_dom UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/TrEMBL
  Transposase-MT_Hybrid UniProtKB/TrEMBL
  Transposase_1 UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report pps:100986203 UniProtKB/TrEMBL
NCBI Gene LOC100986203 ENTREZGENE
PANTHER HISTONE H3 (LYS9) METHYLTRANSFERASE-RELATED UniProtKB/TrEMBL
  HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR UniProtKB/TrEMBL
  HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H UniProtKB/TrEMBL
  MARINER MOS1 TRANSPOSASE-LIKE PROTEIN UniProtKB/TrEMBL
Pfam HTH_48 UniProtKB/TrEMBL
  Pre-SET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
  Transposase_1 UniProtKB/TrEMBL
PROSITE POST_SET UniProtKB/TrEMBL
  PRE_SET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
SMART PreSET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
Superfamily-SCOP SSF82199 UniProtKB/TrEMBL
UniProt A0A2R9BWD0 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BWD5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BX07_PANPA UniProtKB/TrEMBL