Setmar (SET domain without mariner transposase fusion) - Rat Genome Database

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Gene: Setmar (SET domain without mariner transposase fusion) Mus musculus
Analyze
Symbol: Setmar
Name: SET domain without mariner transposase fusion
RGD ID: 1558346
MGI Page MGI
Description: Predicted to have histone-lysine N-methyltransferase activity and zinc ion binding activity. Predicted to be involved in histone lysine methylation. Predicted to localize to chromosome and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and respiratory system. Orthologous to human SETMAR (SET domain and mariner transposase fusion gene).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5830404F24Rik; epidermal tumor expressed transcript 2; Etet2; histone-lysine N-methyltransferase SETMAR; SET domain and mariner transposase fusion gene-containing protein homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396108,042,006 - 108,054,088 (+)NCBIGRCm39mm39
GRCm39 Ensembl6108,042,006 - 108,054,083 (+)Ensembl
GRCm386108,065,045 - 108,077,127 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6108,065,045 - 108,077,122 (+)EnsemblGRCm38mm10GRCm38
MGSCv376108,015,040 - 108,027,114 (+)NCBIGRCm37mm9NCBIm37
MGSCv366108,030,822 - 108,042,902 (+)NCBImm8
Celera6109,874,089 - 109,886,144 (+)NCBICelera
Cytogenetic Map6E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14681479   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16672366   PMID:20620605   PMID:21541502   PMID:21677750  
PMID:23964856  


Genomics

Comparative Map Data
Setmar
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396108,042,006 - 108,054,088 (+)NCBIGRCm39mm39
GRCm39 Ensembl6108,042,006 - 108,054,083 (+)Ensembl
GRCm386108,065,045 - 108,077,127 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6108,065,045 - 108,077,122 (+)EnsemblGRCm38mm10GRCm38
MGSCv376108,015,040 - 108,027,114 (+)NCBIGRCm37mm9NCBIm37
MGSCv366108,030,822 - 108,042,902 (+)NCBImm8
Celera6109,874,089 - 109,886,144 (+)NCBICelera
Cytogenetic Map6E1NCBI
SETMAR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl34,303,304 - 4,317,567 (+)EnsemblGRCh38hg38GRCh38
GRCh3834,303,304 - 4,320,649 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3734,344,988 - 4,358,949 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3634,320,016 - 4,333,949 (+)NCBINCBI36hg18NCBI36
Build 3434,320,070 - 4,333,948NCBI
Celera34,282,941 - 4,296,902 (+)NCBI
Cytogenetic Map3p26.1NCBI
HuRef34,278,470 - 4,292,431 (+)NCBIHuRef
CHM1_134,295,088 - 4,309,040 (+)NCBICHM1_1
Setmar
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24141,046,058 - 141,058,183 (+)NCBI
Rnor_6.0 Ensembl4140,092,352 - 140,105,316 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04140,092,346 - 140,104,495 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04204,560,058 - 204,571,718 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44143,564,021 - 143,576,022 (+)NCBIRGSC3.4rn4RGSC3.4
Celera4129,699,443 - 129,711,306 (+)NCBICelera
Cytogenetic Map4q41NCBI
LOC102020128
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554219,066,906 - 9,080,352 (-)NCBIChiLan1.0ChiLan1.0
LOC100986203
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.134,357,779 - 4,371,810 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl34,357,890 - 4,371,791 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v034,256,539 - 4,271,593 (+)NCBIMhudiblu_PPA_v0panPan3
SETMAR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12013,214,241 - 13,224,020 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2013,214,241 - 13,224,020 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2013,187,342 - 13,197,119 (-)NCBI
ROS_Cfam_1.02013,252,140 - 13,261,903 (-)NCBI
UMICH_Zoey_3.12012,956,313 - 12,966,091 (-)NCBI
UNSW_CanFamBas_1.02013,296,532 - 13,306,290 (-)NCBI
UU_Cfam_GSD_1.02013,283,976 - 13,293,754 (-)NCBI
LOC101962206
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494210,805,678 - 10,817,230 (+)NCBI
SpeTri2.0NW_0049365773,761,078 - 3,771,864 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100514009
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11360,914,412 - 60,933,064 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21367,224,808 - 67,234,390 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SETMAR
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12240,389,390 - 40,403,917 (+)NCBI
ChlSab1.1 Ensembl2240,389,485 - 40,403,898 (+)Ensembl
LOC101704237
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477314,680,571 - 14,692,583 (+)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684122513118122513Mouse
1301687Mnic2_mmacronutrient intake (mouse)Not determined686806805113544602Mouse
1301744Hdlq11_mHDL QTL 11 (mouse)Not determined687503360121503555Mouse
1301262Gasa3_mgastritis type A susceptibility locus 3 (mouse)Not determined689005405123005603Mouse
1301244Ichs_mimmediate cutaneous hypersensitivity QTL (mouse)Not determined690795610124795846Mouse
4141578Obrq1_mobesity resistance QTL 1 (mouse)Not determined92607306112004738Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692607306146429238Mouse
1301292Cfbw2_mcystic fibrosis body weight 2 (mouse)Not determined695004651129004738Mouse
1300704Cia3_mcollagen induced arthritis QTL 3 (mouse)Not determined696347325130347522Mouse
11040599Lmr4b_mleishmaniasis resistance 4b (mouse)696347325130347522Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96655951146633626Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96655951146633626Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696655951146633626Mouse
10043923Bhr7_mbronchial hyperresponsiveness 7 (mouse)Not determined698242853132242977Mouse
1301518Bbaa5_mB.burgdorferi-associated arthritis 5 (mouse)Not determined698506837145935444Mouse
1301923Lith6_mlithogenic gene 6 (mouse)Not determined698717516132717715Mouse
1301915Chab3_mcholesterol absorption 3 (mouse)Not determined698931748132940036Mouse
1302131Bmd8_mbone mineral density 8 (mouse)Not determined699155128133155267Mouse
1300887Pabr1_mplasma apolipoprotein B (human) regulator 1 (mouse)Not determined6103777444136423692Mouse
12910776Hcga4b_mhome cage activity 4b (mouse)6104503360110960065Mouse
1301509Sluc3_msusceptibility to lung cancer 3 (mouse)Not determined6104503360127042975Mouse
1357806Aaj3_manxiety in A/J 3 (mouse)Not determined6104503360136423692Mouse
1357793Pnhdlc1_mplasma non-HDL cholesterol 1 (mouse)Not determined6105564822114368849Mouse
4141699Ibdq2_minflammatory bowel disease QTL 2 (mouse)Not determined106005405120917141Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:563
Count of miRNA genes:338
Interacting mature miRNAs:390
Transcripts:ENSMUST00000049246, ENSMUST00000138140
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000049246   ⟹   ENSMUSP00000048225
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl6108,065,045 - 108,077,122 (+)Ensembl
RefSeq Acc Id: ENSMUST00000138140   ⟹   ENSMUSP00000145263
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl6108,065,062 - 108,077,122 (+)Ensembl
RefSeq Acc Id: NM_001276356   ⟹   NP_001263285
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396108,042,006 - 108,054,088 (+)NCBI
GRCm386108,065,045 - 108,077,127 (+)NCBI
Celera6109,874,088 - 109,886,151 (+)NCBI
Sequence:
RefSeq Acc Id: NM_178391   ⟹   NP_848478
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396108,042,006 - 108,054,088 (+)NCBI
GRCm386108,065,045 - 108,077,127 (+)NCBI
MGSCv376108,015,040 - 108,027,114 (+)RGD
Celera6109,874,088 - 109,886,151 (+)NCBI
cM Map6 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001263285 (Get FASTA)   NCBI Sequence Viewer  
  NP_848478 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH45208 (Get FASTA)   NCBI Sequence Viewer  
  EDK99405 (Get FASTA)   NCBI Sequence Viewer  
  Q80UJ9 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_848478   ⟸   NM_178391
- Peptide Label: isoform 1
- UniProtKB: Q80UJ9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001263285   ⟸   NM_001276356
- Peptide Label: isoform 2
- Sequence:
RefSeq Acc Id: ENSMUSP00000145263   ⟸   ENSMUST00000138140
RefSeq Acc Id: ENSMUSP00000048225   ⟸   ENSMUST00000049246
Protein Domains
Post-SET   Pre-SET   SET

Promoters
RGD ID:6839974
Promoter ID:MM_KWN:47095
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000041969,   OTTMUST00000041970
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366108,014,996 - 108,015,496 (+)MPROMDB
RGD ID:6890578
Promoter ID:EPDNEW_M8740
Type:multiple initiation site
Name:Setmar_1
Description:Mus musculus SET domain without mariner transposase fusion ,transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386108,065,045 - 108,065,105EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1921979 AgrOrtholog
Ensembl Genes ENSMUSG00000034639 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000048225 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000145263 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000049246 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000138140 UniProtKB/TrEMBL
InterPro Post-SET_dom UniProtKB/Swiss-Prot
  Pre-SET_dom UniProtKB/Swiss-Prot
  SET_dom UniProtKB/Swiss-Prot
KEGG Report mmu:74729 UniProtKB/Swiss-Prot
MGD MGI:1921979 ENTREZGENE
NCBI Gene 74729 ENTREZGENE
Pfam Pre-SET UniProtKB/Swiss-Prot
  SET UniProtKB/Swiss-Prot
PhenoGen Setmar PhenoGen
PROSITE POST_SET UniProtKB/Swiss-Prot
  PRE_SET UniProtKB/Swiss-Prot
  SET UniProtKB/Swiss-Prot
SMART PreSET UniProtKB/Swiss-Prot
  SET UniProtKB/Swiss-Prot
UniProt A0A0N4SVW0_MOUSE UniProtKB/TrEMBL
  Q80UJ9 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary E9QLD6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-12 Setmar  SET domain without mariner transposase fusion    SET domain and mariner transposase fusion gene  Symbol and/or name change 5135510 APPROVED