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ONTOLOGY REPORT - ANNOTATIONS


Term:mitotic G1 DNA damage checkpoint signaling
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Accession:GO:0031571 term browser browse the term
Definition:A signal transduction process that contributes to a mitotic cell cycle G1/S transition DNA damage checkpoint.
Synonyms:exact_synonym: intracellular signal transduction involved in G1 DNA damage checkpoint;   intracellular signal transduction involved in G1/S DNA damage checkpoint;   intracellular signal transduction pathway involved in G1 DNA damage checkpoint;   intracellular signal transduction pathway involved in G1/S DNA damage checkpoint;   intracellular signaling cascade involved in G1 DNA damage checkpoint;   intracellular signaling cascade involved in G1/S DNA damage checkpoint;   intracellular signaling chain involved in G1 DNA damage checkpoint;   intracellular signaling chain involved in G1/S DNA damage checkpoint;   intracellular signaling pathway involved in G1 DNA damage checkpoint;   intracellular signaling pathway involved in G1/S DNA damage checkpoint;   mitotic G1 DNA damage checkpoint;   mitotic cell cycle G1/s transition DNA damage checkpoint;   signal transduction via intracellular signaling cascade involved in G1 DNA damage checkpoint;   signal transduction via intracellular signaling cascade involved in G1/S DNA damage checkpoint;   signal transmission via intracellular cascade involved in G1 DNA damage checkpoint
 related_synonym: G1 DNA damage checkpoint;   G1/S DNA damage checkpoint;   signal transduction involved in mitotic G1 DNA damage checkpoint;   signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
 alt_id: GO:0044783;   GO:0072431;   GO:1902400



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mitotic G1 DNA damage checkpoint signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCND1 cyclin D1 involved_in ISO (PMID:19412162) UniProt PMID:19412162 NCBI chr11:64,737,006...64,750,353 JBrowse link
G DGKZ diacylglycerol kinase zeta involved_in ISO (PMID:16286473) UniProt PMID:16286473 NCBI chr11:46,291,592...46,339,127
Ensembl chr11:46,841,605...46,889,763
JBrowse link
G FBXO31 F-box protein 31 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:67,997,481...68,053,081
Ensembl chr16:87,322,364...87,377,104
JBrowse link
G GIGYF2 GRB10 interacting GYF protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19744960) Ensembl
MGI
PMID:19744960 GO_REF:0000107 NCBI chr2B:119,929,004...120,090,367
Ensembl chr2B:238,847,674...239,007,549
JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:44,201,391...44,386,803
Ensembl chr 8:41,593,029...41,778,299
JBrowse link
G RFWD3 ring finger and WD repeat domain 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:55,187,178...55,233,265
Ensembl chr16:74,541,450...74,586,951
JBrowse link
G RPA2 replication protein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:27,151,784...27,175,110
Ensembl chr 1:28,191,731...28,214,666
JBrowse link
G RPS27L ribosomal protein S27 like involved_in ISO (PMID:18056458) UniProt PMID:18056458 NCBI chr15:42,101,137...42,105,019
Ensembl chr15:60,397,131...60,400,643
JBrowse link
G SDE2 SDE2 telomere maintenance homolog involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:201,443,945...201,460,668
Ensembl chr 1:206,441,517...206,457,679
JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16107883) Ensembl
MGI
PMID:16107883 GO_REF:0000107 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
G TREX1 three prime repair exonuclease 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23993650)
(PMID:18045533)
Ensembl
MGI
PMID:18045533 PMID:23993650 GO_REF:0000107 NCBI chr 3:48,387,762...48,389,693
Ensembl chr 3:49,470,222...49,471,331
JBrowse link
G WAC WW domain containing adaptor with coiled-coil involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:28,685,294...28,777,176
Ensembl chr10:29,042,331...29,130,591
JBrowse link
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP2 caspase 2 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 7:135,283,072...135,307,855
Ensembl chr 7:147,773,749...147,792,958
JBrowse link
G CASP9 caspase 9 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:14,630,659...14,662,865
Ensembl chr 1:15,624,666...15,656,266
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599
JBrowse link
G CRADD CASP2 and RIPK1 domain containing adaptor with death domain involved_in ISO (PMID:21726810) UniProt PMID:21726810 NCBI chr12:91,220,813...91,593,799 JBrowse link
G E2F7 E2F transcription factor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:74,540,049...74,582,561
Ensembl chr12:77,388,950...77,433,262
JBrowse link
G LOC100977427 large ribosomal subunit protein uL24 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:56,616,749...56,617,299
Ensembl chr17:48,009,198...48,015,977
JBrowse link
G MDM2 MDM2 proto-oncogene involved_in ISO (PMID:21726810) UniProt PMID:21726810 NCBI chr12:66,322,340...66,357,010
Ensembl chr12:69,102,084...69,133,278
JBrowse link
G MUC1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) BHF-UCL PMID:15710329 NCBI chr 1:130,533,508...130,537,866
Ensembl chr 1:134,141,969...134,145,850
JBrowse link
G PCBP4 poly(rC) binding protein 4 involved_in ISO (PMID:10891498) UniProt PMID:10891498 NCBI chr 3:51,898,857...51,908,932
Ensembl chr 3:53,127,448...53,137,293
JBrowse link
G PIDD1 p53-induced death domain protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:816,629...827,295
Ensembl chr11:860,899...867,436
JBrowse link
G PML PML nuclear body scaffold involved_in ISO (MGI:3580934|PMID:15626733) UniProt PMID:15626733 MGI:3580934 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883
JBrowse link
G PPP2R5C protein phosphatase 2 regulatory subunit B'gamma involved_in ISO (PMID:17245430) UniProt PMID:17245430 NCBI chr14:82,383,086...82,549,822
Ensembl chr14:102,206,396...102,372,978
JBrowse link
G PRAP1 proline rich acidic protein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr10:134,248,728...134,268,442 JBrowse link
G RBM38 RNA binding motif protein 38 involved_in ISO (PMID:17050675) UniProt PMID:17050675 NCBI chr20:53,731,641...53,749,688 JBrowse link
G RPL26 ribosomal protein L26 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:43,274,839...43,282,606
Ensembl chr17:48,009,198...48,015,977
JBrowse link
G TP53 tumor protein p53 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16107883) Ensembl
MGI
PMID:16107883 GO_REF:0000107 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    cellular process 15499
      cell cycle process 1277
        mitotic cell cycle process 745
          mitotic cell cycle checkpoint signaling 139
            mitotic G1/S transition checkpoint signaling 29
              mitotic G1 DNA damage checkpoint signaling 27
                DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 16
Path 2
Term Annotations click to browse term
  biological_process 16440
    biological regulation 11453
      regulation of biological process 11104
        regulation of cellular process 10598
          regulation of cell cycle 1038
            regulation of cell cycle process 723
              negative regulation of cell cycle process 296
                negative regulation of cell cycle phase transition 247
                  cell cycle checkpoint signaling 181
                    DNA integrity checkpoint signaling 130
                      DNA damage checkpoint signaling 122
                        mitotic DNA damage checkpoint signaling 85
                          mitotic G1 DNA damage checkpoint signaling 27
                            DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 16
paths to the root