CRADD (CASP2 and RIPK1 domain containing adaptor with death domain) - Rat Genome Database

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Gene: CRADD (CASP2 and RIPK1 domain containing adaptor with death domain) Pan paniscus
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Symbol: CRADD
Name: CASP2 and RIPK1 domain containing adaptor with death domain
RGD ID: 11767656
Description: ENCODES a protein that exhibits death domain binding (ortholog); protease binding (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN apoptotic signaling pathway (ortholog); cellular response to mechanical stimulus (ortholog); DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (ortholog); PARTICIPATES IN ceramide signaling pathway; ASSOCIATED WITH arrhythmogenic right ventricular cardiomyopathy (ortholog); autosomal recessive intellectual developmental disorder 34 (ortholog); Developmental Disabilities (ortholog); FOUND IN cytoplasm (ortholog); endopeptidase complex (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: death domain-containing protein CRADD
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210101,720,799 - 102,094,687 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112101,717,193 - 101,937,321 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01291,220,813 - 91,593,799 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11294,619,877 - 94,836,970 (+)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CRADD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210101,720,799 - 102,094,687 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112101,717,193 - 101,937,321 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01291,220,813 - 91,593,799 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11294,619,877 - 94,836,970 (+)NCBIpanpan1.1PanPan1.1panPan2
CRADD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381293,677,375 - 93,894,840 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1293,677,375 - 93,894,840 (+)EnsemblGRCh38hg38GRCh38
GRCh371294,071,151 - 94,288,616 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361292,595,282 - 92,768,663 (+)NCBINCBI36Build 36hg18NCBI36
Build 341292,573,618 - 92,746,997NCBI
Celera1293,741,644 - 93,915,013 (+)NCBICelera
Cytogenetic Map12q22NCBI
HuRef1291,137,880 - 91,311,191 (+)NCBIHuRef
CHM1_11294,036,232 - 94,209,574 (+)NCBICHM1_1
T2T-CHM13v2.01293,658,870 - 93,876,341 (+)NCBIT2T-CHM13v2.0
Cradd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391095,010,601 - 95,160,000 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1095,010,608 - 95,159,995 (-)EnsemblGRCm39 Ensembl
GRCm381095,174,739 - 95,324,138 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1095,174,746 - 95,324,133 (-)EnsemblGRCm38mm10GRCm38
MGSCv371094,637,380 - 94,786,731 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361094,604,434 - 94,753,785 (-)NCBIMGSCv36mm8
Celera1097,149,089 - 97,298,972 (-)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1049.26NCBI
Cradd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8731,827,131 - 31,839,796 (-)NCBIGRCr8
mRatBN7.2729,940,240 - 29,952,907 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl729,798,586 - 29,952,907 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx731,927,620 - 31,940,283 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0734,100,876 - 34,113,560 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0733,869,731 - 33,882,409 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0736,395,665 - 36,408,588 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl736,395,665 - 36,408,588 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0736,457,911 - 36,470,834 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4732,504,279 - 32,517,581 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1732,379,423 - 32,536,642 (-)NCBI
Celera727,014,185 - 27,026,498 (-)NCBICelera
Cytogenetic Map7q13NCBI
CRADD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11533,873,600 - 34,052,498 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1533,878,467 - 34,092,094 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1534,323,893 - 34,502,937 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01534,542,199 - 34,714,967 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1534,546,434 - 34,754,560 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11533,815,780 - 33,988,870 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01533,905,303 - 34,078,557 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01534,174,303 - 34,346,975 (+)NCBIUU_Cfam_GSD_1.0
Cradd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494525,972,089 - 26,167,311 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650710,098,171 - 10,264,716 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650710,077,345 - 10,264,705 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRADD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11189,066,952 - 89,246,177 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037155,916,158 - 156,095,333 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cradd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475013,063,009 - 13,254,499 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475013,065,300 - 13,309,439 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_003816868   ⟹   XP_003816916
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v210101,720,799 - 101,893,861 (+)NCBI
NHGRI_mPanPan112101,717,193 - 101,890,257 (+)NCBI
Mhudiblu_PPA_v01291,220,813 - 91,393,890 (+)NCBI
PanPan1.11294,619,877 - 94,792,808 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055095990   ⟹   XP_054951965
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v210101,720,987 - 101,893,861 (+)NCBI
NHGRI_mPanPan112101,717,377 - 101,890,257 (+)NCBI
RefSeq Acc Id: XM_063593566   ⟹   XP_063449636
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v210101,720,817 - 101,729,053 (+)NCBI
RefSeq Acc Id: XM_063593567   ⟹   XP_063449637
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v210101,720,817 - 102,094,687 (+)NCBI
RefSeq Acc Id: XM_063593568   ⟹   XP_063449638
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v210101,720,817 - 101,842,568 (+)NCBI
RefSeq Acc Id: XR_010108940
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v210101,720,817 - 101,940,929 (+)NCBI
RefSeq Acc Id: XP_003816916   ⟸   XM_003816868
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_054951965   ⟸   XM_055095990
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063449637   ⟸   XM_063593567
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063449638   ⟸   XM_063593568
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063449636   ⟸   XM_063593566
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
NCBI Gene CRADD ENTREZGENE