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ONTOLOGY REPORT - ANNOTATIONS


Term:zymogen granule
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Accession:GO:0042588 term browser browse the term
Definition:A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme.



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zymogen granule term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cel carboxyl ester lipase IDA RGD PMID:9701565 RGD:2313571 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035
JBrowse link
G Cuzd1 CUB and zona pellucida-like domains 1 located_in ISO (PMID:12401800) RGD PMID:12401800 NCBI chr 1:186,089,422...186,130,536
Ensembl chr 1:186,089,423...186,102,546
JBrowse link
G Dnase1 deoxyribonuclease 1 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869
JBrowse link
G Gnai3 G protein subunit alpha i3 IDA RGD PMID:12038977 RGD:728690 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IDA RGD PMID:8675995 RGD:2298714 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Mta1 metastasis associated 1 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 6:132,178,608...132,217,641
Ensembl chr 6:132,178,853...132,217,641
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase IDA RGD PMID:10580430 RGD:9590169 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146
JBrowse link
G Pla2g4a phospholipase A2 group 4A IDA RGD PMID:17148545 RGD:1642447 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Rab3d RAB3D, member RAS oncogene family located_in ISO (PMID:12192047) RGD PMID:12192047 NCBI chr 8:20,438,622...20,449,269
Ensembl chr 8:20,439,294...20,449,185
JBrowse link
G Reg1a regenerating family member 1 alpha IDA RGD PMID:12764608 RGD:9831428 NCBI chr 4:110,892,451...110,895,115
Ensembl chr 4:110,892,453...110,895,570
JBrowse link
G Reg3b regenerating family member 3 beta IDA RGD PMID:12764608 RGD:9831428 NCBI chr 4:110,861,775...110,865,015
Ensembl chr 4:110,861,775...110,865,015
JBrowse link
G Srgn serglycin IDA RGD PMID:12602945 RGD:2316805 NCBI chr20:30,442,810...30,479,549
Ensembl chr20:30,442,813...30,457,406
JBrowse link
G Vamp8 vesicle-associated membrane protein 8 located_in ISO (PMID:18535671) RGD PMID:18535671 NCBI chr 4:104,442,383...104,452,884
Ensembl chr 4:104,442,393...104,452,897
JBrowse link
zymogen granule membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa4 annexin A4 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161
JBrowse link
G Anxa5 annexin A5 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Clca1 chloride channel accessory 1 IDA RGD PMID:18616988 RGD:4188872 NCBI chr 2:233,938,677...233,964,369
Ensembl chr 2:233,938,677...233,964,369
JBrowse link
G Cuzd1 CUB and zona pellucida-like domains 1 located_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:12401800)
UniProt
Ensembl
RGD
PMID:12401800 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:186,089,422...186,130,536
Ensembl chr 1:186,089,423...186,102,546
JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 located_in ISS
ISO
GO_REF:0000024
(PMID:7876332)
UniProt
RGD
PMID:7876332 GO_REF:0000024 NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478
JBrowse link
G Gp2 glycoprotein 2 located_in ISO
IDA
(PMID:2011597)
PMID:1999417
RGD PMID:2011597 PMID:1999417 RGD:633018 NCBI chr 1:173,797,057...173,812,619
Ensembl chr 1:173,797,057...173,812,619
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 IDA RGD PMID:18216164 RGD:2317969 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Pnliprp2 pancreatic lipase related protein 2 located_in IDA
IEA
GO_REF:0000044 UniProt
RGD
PMID:8486693 GO_REF:0000044, RGD:633718 NCBI chr 1:257,897,766...257,916,434
Ensembl chr 1:257,897,766...257,916,434
JBrowse link
G Rab27b RAB27B, member RAS oncogene family IDA RGD PMID:15451418 RGD:1303344 NCBI chr18:63,597,554...63,794,124
Ensembl chr18:63,600,937...63,757,180
JBrowse link
G Rab5a RAB5A, member RAS oncogene family IDA RGD PMID:8166729 RGD:2306267 NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873
JBrowse link
G Scamp1 secretory carrier membrane protein 1 located_in IEA
ISO
GO_REF:0000107
(PMID:12192047)
Ensembl
RGD
PMID:12192047 GO_REF:0000107 NCBI chr 2:25,433,958...25,516,734
Ensembl chr 2:25,433,959...25,516,673
JBrowse link
G Slc30a2 solute carrier family 30 member 2 located_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:20133611)
Ensembl
UniProt
RGD
PMID:20133611 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:146,559,733...146,571,957
Ensembl chr 5:146,559,733...146,571,956
JBrowse link
G Slc9a4 solute carrier family 9 member A4 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 9:42,825,334...42,879,729
Ensembl chr 9:42,825,064...42,879,422
JBrowse link
G Stx3 syntaxin 3 located_in
is_active_in
IEA
ISO
GO_REF:0000107
(PMID:18535671)
PR:Q64324 (PMID:18535671)
Ensembl
RGD
PMID:18535671 GO_REF:0000107 NCBI chr 1:208,617,018...208,686,240
Ensembl chr 1:208,639,115...208,685,805
JBrowse link
G Stxbp2 syntaxin binding protein 2 is_active_in
located_in
ISO PR:Q64704 (PMID:18535671) RGD PMID:18535671 NCBI chr12:1,689,364...1,701,145
Ensembl chr12:1,689,410...1,700,458
JBrowse link
G Sycn syncollin located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 1:83,823,836...83,833,542
Ensembl chr 1:83,832,102...83,833,538
JBrowse link
G Tmed10 transmembrane p24 trafficking protein 10 located_in IDA
IEA
ISO
PMID:8663407
PMID:17101722
GO_REF:0000107
(PMID:17101722)
Ensembl
RGD
PMID:17101722 PMID:8663407 PMID:8663407 PMID:17101722 GO_REF:0000107, RGD:68840, RGD:68840, RGD:2317246 NCBI chr 6:104,991,843...105,026,705
Ensembl chr 6:104,991,838...105,026,753
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 located_in IDA PMID:8663407 HGNC-UCL PMID:8663407 RGD:68840 NCBI chr12:32,052,542...32,061,628
Ensembl chr12:32,052,543...32,071,903
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 located_in ISO (PMID:12192047) RGD PMID:12192047 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809
JBrowse link
G Vamp8 vesicle-associated membrane protein 8 located_in IEA GO_REF:0000044 UniProt GO_REF:0000044 NCBI chr 4:104,442,383...104,452,884
Ensembl chr 4:104,442,393...104,452,897
JBrowse link
G Zg16 zymogen granule protein 16 IDA RGD PMID:10648640 RGD:727222 NCBI chr 1:181,657,722...181,660,079
Ensembl chr 1:181,657,722...181,660,079
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20827
    cellular anatomical structure 20627
      endomembrane system 4341
        secretory granule 469
          zymogen granule 32
            zymogen granule membrane 21
Path 2
Term Annotations click to browse term
  cellular_component 20827
    cellular anatomical structure 20627
      organelle 13970
        membrane-bounded organelle 12557
          vesicle 2242
            intracellular vesicle 2058
              cytoplasmic vesicle 2049
                secretory vesicle 742
                  secretory granule 469
                    zymogen granule 32
                      zymogen granule membrane 21
paths to the root