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ONTOLOGY REPORT - ANNOTATIONS

Term:microglia differentiation
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Accession:GO:0014004 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system.
Synonyms:exact_synonym: microglial cell differentiation


show annotations for term's descendants           Sort by:
microglia differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO MGI:1857079 (PMID:23717624) RGD PMID:23717624 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (PMID:17954912) RGD PMID:17954912 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Mfsd8 major facilitator superfamily domain containing 8 acts_upstream_of_or_within ISO (PMID:27654426) RGD PMID:27654426 NCBI chr 2:123,822,042...123,847,808
Ensembl chr 2:123,816,614...123,857,971 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor acts_upstream_of_or_within ISO MGI:2385681 (PMID:18509511) RGD PMID:18509511 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO MGI:1934018 (PMID:18509511) RGD PMID:18509511 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Ndp norrin cystine knot growth factor NDP acts_upstream_of_or_within ISO MGI:2676199 (PMID:29654250) RGD PMID:29654250 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:29890290)		 Ensembl
RGD		 PMID:29890290 GO_REF:0000107 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Qki QKI, KH domain containing RNA binding involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:6514532|PMID:33378678)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:33378678 GO_REF:0000024 GO_REF:0000107 MGI:6514532 NCBI chr 1:50,387,716...50,501,568
Ensembl chr 1:50,387,698...50,498,831 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1860885 (PMID:18509511)		 Ensembl
RGD		 PMID:18509511 GO_REF:0000107 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Vps13a vacuolar protein sorting 13 homolog A acts_upstream_of_or_within ISO (PMID:37714309) RGD PMID:37714309 NCBI chr 1:213,901,999...214,128,638
Ensembl chr 1:213,901,999...214,128,555 		JBrowse link
G Vps54 VPS54 subunit of GARP complex involved_in IEA
ISO		 GO_REF:0000107
MGI:1857091 (PMID:29890290)		 Ensembl
RGD		 PMID:29890290 GO_REF:0000107 NCBI chr14:95,378,821...95,455,871
Ensembl chr14:95,378,012...95,455,857 		JBrowse link
microglia development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO
IEA		 UniProtKB:P49768|UniProtKB:Q9QUN7 (PMID:22198949)
GO_REF:0000107		 RGD
Ensembl		 PMID:22198949 GO_REF:0000107 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:33450391 RGD:126781687 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Itgam integrin subunit alpha M acts_upstream_of_or_within ISO (PMID:20578039) RGD PMID:20578039 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Nrros negative regulator of reactive oxygen species involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:6141908|PMID:28459434), (MGI:6192878|PMID:29909984)		 UniProt
Ensembl
RGD		 PMID:28459434 PMID:29909984 GO_REF:0000024 GO_REF:0000107 MGI:6141908 MGI:6192878 NCBI chr11:68,628,641...68,646,152
Ensembl chr11:68,628,712...68,646,142 		JBrowse link
G Tlr2 toll-like receptor 2 involved_in ISO UniProtKB:P05067|UniProtKB:P49768 (MGI:5307186|PMID:22198949) RGD PMID:22198949 MGI:5307186 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tspan2 tetraspanin 2 acts_upstream_of_or_within ISO MGI:5556057|MGI:97623 (PMID:24038504) RGD PMID:24038504 NCBI chr 2:190,177,717...190,234,994
Ensembl chr 2:190,177,741...190,219,660 		JBrowse link
positive regulation of microglia differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6192878|PMID:29909984)		 UniProt
RGD		 PMID:29909984 GO_REF:0000024 MGI:6192878 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    developmental process 6963
      cellular developmental process 4695
        cell differentiation 4694
          glial cell differentiation 325
            microglia differentiation 18
              microglia development 6
              negative regulation of microglia differentiation 0
              positive regulation of microglia differentiation 1
              regulation of microglia differentiation + 1
Path 2
Term Annotations click to browse term
  biological_process 19692
    developmental process 6963
      anatomical structure development 6486
        multicellular organism development 5239
          system development 4526
            nervous system development 2801
              neurogenesis 2065
                gliogenesis 441
                  glial cell differentiation 325
                    microglia differentiation 18
                      microglia development 6
                      negative regulation of microglia differentiation 0
                      positive regulation of microglia differentiation 1
                      regulation of microglia differentiation + 1
paths to the root