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ONTOLOGY REPORT - ANNOTATIONS

Term:mitochondrial fusion
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Accession:GO:0008053 term browser browse the term
Definition:Merging of two or more mitochondria within a cell to form a single compartment.
Synonyms:exact_synonym: mitochondrion fusion
 related_synonym: mitochondrial membrane fusion
 alt_id: GO:1990613


show annotations for term's descendants           Sort by:
mitochondrial fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afg3l1 AFG3 (ATPase family gene 3)-like 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr19:51,508,612...51,535,773
Ensembl chr19:51,508,613...51,537,396 		JBrowse link
G Afg3l2 AFG3 like matrix AAA peptidase subunit 2 acts_upstream_of_or_within ISO MGI:1928277 (PMID:20038678) RGD PMID:20038678 NCBI chr18:60,954,268...60,999,110
Ensembl chr18:60,954,268...60,999,110 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 acts_upstream_of_or_within ISO MGI:99702 (PMID:16893972), (PMID:17035996) RGD PMID:16893972 PMID:17035996 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within		 ISO
ISS
IBA		 (PMID:14769861)
GO_REF:0000024
GO_REF:0000033
MGI:1097161 (PMID:16893972), (PMID:17035996)		 RGD
UniProt
GO_Central		 PMID:14769861 PMID:16893972 PMID:17035996 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2a1 BCL2-related protein A1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998 		JBrowse link
G Chchd3 coiled-coil-helix-coiled-coil-helix domain containing 3 involved_in ISO (PMID:21081504) RGD PMID:21081504 NCBI chr 4:61,360,352...61,616,850
Ensembl chr 4:61,360,353...61,616,847 		JBrowse link
G Fundc1 FUN14 domain containing 1 involved_in ISO FB:FBgn0026479|FB:FBgn0029891|FB:FBgn0032200 (PMID:37931419) RGD PMID:37931419 NCBI chr  X:5,083,635...5,100,293
Ensembl chr  X:5,083,617...5,100,284 		JBrowse link
G Gdap1 ganglioside-induced differentiation-associated-protein 1 involved_in ISO
IBA		 (PMID:21753178)
GO_REF:0000033		 RGD
GO_Central		 PMID:21753178 GO_REF:0000033 NCBI chr 5:1,932,613...1,951,691
Ensembl chr 5:1,932,613...2,030,061 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mfn1 mitofusin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA
ISS		 GO_REF:0000107
MGI:2450304 (PMID:12527753)
GO_REF:0000033
GO_REF:0000002
(PMID:12759376), (PMID:20436456), (PMID:23921378), (PMID:27920125), (PMID:28114303)
UniProtKB:Q80U63 (MGI:5574552|PMID:24513856), (MGI:6377920|PMID:15899901)
GO_REF:0000024		 Ensembl
RGD
GO_Central
InterPro
UniProt		 PMID:12527753 PMID:12759376 PMID:15899901 PMID:20436456 PMID:23921378 More... GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:5574552 MGI:6377920 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640 		JBrowse link
G Mfn2 mitofusin 2 acts_upstream_of_or_within
involved_in		 IMP
ISO
IBA
IEA
ISS		 MGI:2450306 (PMID:12527753), (PMID:22493254)
GO_REF:0000033
GO_REF:0000107
UniProtKB:Q811U4 (MGI:5574552|PMID:24513856), (MGI:6377920|PMID:15899901)
GO_REF:0000024
(PMID:23921378)		 RGD
GO_Central
Ensembl
UniProt		 PMID:12527753 PMID:15899901 PMID:22493254 PMID:23921378 PMID:24513856 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:5574552 MGI:6377920, RGD:1304446 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mief1 mitochondrial elongation factor 1 NOT|involved_in ISO (PMID:23921378) RGD PMID:23921378 NCBI chr 7:111,786,630...111,802,220
Ensembl chr 7:111,786,709...111,802,220 		JBrowse link
G Mief2 mitochondrial elongation factor 2 NOT|involved_in ISO (PMID:23921378) RGD PMID:23921378 NCBI chr10:45,408,055...45,414,144
Ensembl chr10:45,408,082...45,414,144 		JBrowse link
G Miga1 mitoguardin 1 involved_in ISO
IBA		 (PMID:26711011)
GO_REF:0000033
(MGI:5707521|PMID:26711011)		 RGD
GO_Central		 PMID:26711011 GO_REF:0000033 MGI:5707521 NCBI chr 2:241,224,118...241,279,174
Ensembl chr 2:241,226,015...241,279,106 		JBrowse link
G Miga2 mitoguardin 2 involved_in ISO
IBA		 (PMID:26711011)
GO_REF:0000033
(MGI:5707521|PMID:26711011)		 RGD
GO_Central		 PMID:26711011 GO_REF:0000033 MGI:5707521 NCBI chr 3:13,636,235...13,658,895
Ensembl chr 3:13,636,238...13,658,896 		JBrowse link
G Nme3 NME/NM23 nucleoside diphosphate kinase 3 involved_in ISO (PMID:30587587) RGD PMID:30587587 NCBI chr10:13,917,309...13,918,415
Ensembl chr10:13,917,403...13,918,359 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(MGI:6377920|PMID:15899901)
(PMID:17545159), (PMID:20185555), (PMID:20436456)		 ParkinsonsUK-UCL
GO_Central
RGD		 PMID:15899901 PMID:17545159 PMID:20185555 PMID:20436456 GO_REF:0000024 GO_REF:0000033 MGI:6377920 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISO (MGI:6450250|PMID:16713954) RGD PMID:16713954 MGI:6450250 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506 		JBrowse link
G Pld6 phospholipase D family, member 6 involved_in ISO (PMID:17028579) RGD PMID:17028579 NCBI chr10:44,578,536...44,581,187
Ensembl chr10:44,577,675...44,581,077 		JBrowse link
G Rcc1l RCC1 like involved_in ISO (PMID:28746876)
(MGI:6104022|PMID:28746876)		 RGD PMID:28746876 MGI:6104022 NCBI chr12:22,543,125...22,574,042
Ensembl chr12:22,543,734...22,574,036 		JBrowse link
G Thg1l tRNA-histidine guanylyltransferase 1-like involved_in ISS
ISO		 GO_REF:0000024
(PMID:25008184)		 UniProt
RGD		 PMID:25008184 GO_REF:0000024 NCBI chr10:30,387,929...30,396,579
Ensembl chr10:30,387,940...30,396,687 		JBrowse link
G Usp30 ubiquitin specific peptidase 30 involved_in ISO (MGI:5574552|PMID:24513856) RGD PMID:24513856 MGI:5574552 NCBI chr12:42,501,345...42,555,311
Ensembl chr12:42,501,348...42,555,616 		JBrowse link
mitochondrial inner membrane fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISO
ISS
IEA		 (PMID:32228866)
(PMID:28628083)
(PMID:31922487), (PMID:37612504), (PMID:37612506)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:28628083 PMID:31922487 PMID:32228866 PMID:37612504 PMID:37612506 GO_REF:0000024 GO_REF:0000107 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
negative regulation of mitochondrial fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adck1 aarF domain containing kinase 1 involved_in ISO (PMID:31125351) RGD PMID:31125351 NCBI chr 6:107,277,170...107,377,057
Ensembl chr 6:107,277,244...107,377,055 		JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in ISO (PMID:20436456) RGD PMID:20436456 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Dnm1l dynamin 1-like involved_in IMP PMID:23792689 CAFA PMID:23792689 RGD:12793033 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482 		JBrowse link
G Huwe1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 involved_in ISO (PMID:26214738) RGD PMID:26214738 NCBI chr  X:20,873,795...21,001,378
Ensembl chr  X:20,873,795...21,001,262 		JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:19407830) RGD PMID:19407830 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863 		JBrowse link
G Oma1 OMA1 zinc metallopeptidase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5426110|PMID:22433842)
(PMID:20038677)		 UniProt
Ensembl
RGD		 PMID:20038677 PMID:22433842 GO_REF:0000024 GO_REF:0000107 MGI:5426110 NCBI chr 5:118,083,728...118,136,980
Ensembl chr 5:118,083,728...118,136,980 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISS GO_REF:0000024 ParkinsonsUK-UCL GO_REF:0000024 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Tfrc transferrin receptor involved_in ISO (PMID:26214738) RGD PMID:26214738 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Vat1 vesicle amine transport 1 involved_in ISO
IBA		 (PMID:17105775)
GO_REF:0000033		 RGD
GO_Central		 PMID:17105775 GO_REF:0000033 NCBI chr10:86,389,549...86,397,167
Ensembl chr10:86,389,545...86,397,224 		JBrowse link
positive regulation of mitochondrial fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mfn1 mitofusin 1 IMP RGD PMID:24751540 RGD:13204834 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640 		JBrowse link
G Mief1 mitochondrial elongation factor 1 involved_in ISO
ISS		 (PMID:33632269)
GO_REF:0000024		 RGD
UniProt		 PMID:33632269 GO_REF:0000024 NCBI chr 7:111,786,630...111,802,220
Ensembl chr 7:111,786,709...111,802,220 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase IMP RGD PMID:22442078 RGD:7829728 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Pld6 phospholipase D family, member 6 acts_upstream_of_or_within ISO (PMID:24599962) RGD PMID:24599962 NCBI chr10:44,578,536...44,581,187
Ensembl chr10:44,577,675...44,581,077 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
ISS		 (PMID:23453807)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
ParkinsonsUK-UCL		 PMID:23453807 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Yme1l1 YME1-like 1 ATPase involved_in ISO
IEA
ISS		 (PMID:33237841)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:33237841 GO_REF:0000024 GO_REF:0000107 NCBI chr17:85,287,607...85,326,068
Ensembl chr17:85,287,554...85,326,335 		JBrowse link
G Zdhhc6 zinc finger DHHC-type palmitoyltransferase 6 involved_in ISO (PMID:26214738) RGD PMID:26214738 NCBI chr 1:254,335,472...254,356,141
Ensembl chr 1:254,335,113...254,356,108 		JBrowse link
regulation of mitochondrial fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtch2 mitochondrial carrier 2 involved_in ISO (MGI:6267820|PMID:30510213) RGD PMID:30510213 MGI:6267820 NCBI chr 3:76,830,549...76,850,189
Ensembl chr 3:76,830,413...76,850,189 		JBrowse link
stress-induced mitochondrial fusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Stoml2 stomatin like 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3849358|PMID:19360003)		 UniProt
RGD		 PMID:19360003 GO_REF:0000024 MGI:3849358 NCBI chr 5:57,256,227...57,259,824
Ensembl chr 5:57,256,220...57,259,920 		JBrowse link
G Thg1l tRNA-histidine guanylyltransferase 1-like involved_in ISO
IEA
ISS		 (PMID:25008184)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:25008184 GO_REF:0000024 GO_REF:0000107 NCBI chr10:30,387,929...30,396,579
Ensembl chr10:30,387,940...30,396,687 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    cellular process 18525
      cellular component organization or biogenesis 7044
        cellular component organization 6793
          organelle organization 3691
            organelle fusion 165
              mitochondrial fusion 35
                mitochondrial inner membrane fusion 1
                mitochondrial outer membrane fusion 0
                negative regulation of mitochondrial fusion 9
                positive regulation of mitochondrial fusion 7
                regulation of mitochondrial fusion + 16
                stress-induced mitochondrial fusion 2
paths to the root