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ONTOLOGY REPORT - ANNOTATIONS

Term:one-carbon metabolic process
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Accession:GO:0006730 term browser browse the term
Definition:The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
Synonyms:exact_synonym: one carbon metabolism;   one-carbon transfer metabolic process;   one-carbon transfer metabolism
 alt_id: GO:0019753;   GO:0019754
 xref: UM-BBD_pathwayID:C1cyc


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one-carbon metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHCY adenosylhomocysteinase involved_in IEA UniProt GO_REF:0000043 NCBI chr17:37,726,084...37,744,378
Ensembl chr17:37,726,084...37,744,461 		JBrowse link
G AHCYL1 adenosylhomocysteinase like 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 4:110,092,976...110,132,826
Ensembl chr 4:110,092,907...110,132,646 		JBrowse link
G AHCYL2 adenosylhomocysteinase like 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr18:19,260,226...19,441,839
Ensembl chr18:19,260,228...19,441,883 		JBrowse link
G ALDH1L1 aldehyde dehydrogenase 1 family member L1 involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr 7:53,748,585...53,794,777
Ensembl chr 7:53,748,653...53,794,706 		JBrowse link
G ALDH1L2 aldehyde dehydrogenase 1 family member L2 involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr 5:79,492,672...79,558,702
Ensembl chr 5:79,492,750...79,558,701 		JBrowse link
G CA1 carbonic anhydrase 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 4:51,343,548...51,353,127
Ensembl chr 4:51,302,406...51,353,126 		JBrowse link
G CA10 carbonic anhydrase 10 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:27,979,321...28,619,022
Ensembl chr12:27,979,331...28,615,807 		JBrowse link
G CA11 carbonic anhydrase 11 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:53,993,183...53,999,357
Ensembl chr 6:53,993,394...53,999,172 		JBrowse link
G CA12 carbonic anhydrase 12 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:108,649,277...108,710,658
Ensembl chr 1:108,649,271...108,710,651 		JBrowse link
G CA13 carbonic anhydrase 13 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 4:51,406,755...51,468,971
Ensembl chr 4:51,408,184...51,468,973 		JBrowse link
G CA14 carbonic anhydrase 14 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:98,821,577...98,828,934
Ensembl chr 4:98,821,579...98,828,736 		JBrowse link
G CA2 carbonic anhydrase 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 4:51,194,686...51,211,436
Ensembl chr 4:51,193,756...51,211,259 		JBrowse link
G CA3 carbonic anhydrase 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 4:51,227,485...51,237,861
Ensembl chr 4:51,227,485...51,237,844 		JBrowse link
G CA4 carbonic anhydrase 4 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr12:37,962,951...37,972,443
Ensembl chr12:37,962,943...37,972,509 		JBrowse link
G CA6 carbonic anhydrase 6 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:69,447,662...69,468,819
Ensembl chr 6:69,447,439...69,468,821 		JBrowse link
G CA7 carbonic anhydrase 7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:27,548,647...27,563,966
Ensembl chr 6:27,548,706...27,563,861 		JBrowse link
G CA9 carbonic anhydrase 9 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:236,393,727...236,400,994
Ensembl chr 1:236,394,306...236,400,822 		JBrowse link
G CCNG1 cyclin G1 involved_in IEA UniProt GO_REF:0000043 NCBI chr16:60,349,255...60,356,737
Ensembl chr16:60,349,258...60,356,738 		JBrowse link
G DHFR dihydrofolate reductase involved_in IEA UniProt GO_REF:0000043 NCBI chr 2:89,230,660...89,255,830 JBrowse link
G EPGN epithelial mitogen involved_in IEA UniProt GO_REF:0000043 NCBI chr 8:70,266,867...70,301,250
Ensembl chr 8:70,292,467...70,300,149 		JBrowse link
G FPGS folylpolyglutamate synthase involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:268,281,298...268,309,397
Ensembl chr 1:268,287,765...268,309,398 		JBrowse link
G GNMT glycine N-methyltransferase involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:17937387) Ensembl
MGI
GO_Central
TreeGrafter		 PMID:17937387 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:38,038,359...38,041,218
Ensembl chr 7:38,038,358...38,041,217 		JBrowse link
G MAT1A methionine adenosyltransferase 1A involved_in IEA UniProt GO_REF:0000043 NCBI chr14:82,109,405...82,126,487
Ensembl chr14:82,107,390...82,127,049 		JBrowse link
G MAT2A methionine adenosyltransferase 2A involved_in IEA UniProt GO_REF:0000043 NCBI chr 3:59,220,203...59,225,097
Ensembl chr 3:59,218,688...59,225,249 		JBrowse link
G MAT2B methionine adenosyltransferase 2B involved_in IEA UniProt GO_REF:0000043 NCBI chr16:60,255,541...60,274,228
Ensembl chr16:60,255,358...60,274,135 		JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO
IEA		 RGD
Ensembl
UniProt		 PMID:14597174 GO_REF:0000043 GO_REF:0000107 RGD:1302361 NCBI chr 7:88,471,317...88,533,690
Ensembl chr 7:88,471,414...88,537,387 		JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:15,140,929...15,330,265
Ensembl chr 1:15,140,899...15,329,986 		JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase involved_in IEA UniProt GO_REF:0000043 NCBI chr 3:68,819,171...68,833,641
Ensembl chr 3:68,818,119...68,833,600 		JBrowse link
G MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like involved_in IEA UniProt GO_REF:0000043 NCBI chr 8:70,179,701...70,288,356
Ensembl chr 8:70,179,658...70,290,047 		JBrowse link
G SFXN1 sideroflexin 1 acts_upstream_of
involved_in		 ISS
IEA		 UniProt GO_REF:0000024 GO_REF:0000043 NCBI chr 2:82,025,799...82,057,629
Ensembl chr 2:82,025,820...82,057,564 		JBrowse link
G SFXN3 sideroflexin 3 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:30442778) UniProt
Ensembl		 PMID:30442778 GO_REF:0000107 NCBI chr14:112,111,483...112,119,166
Ensembl chr14:112,111,569...112,119,162 		JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr12:60,414,421...60,435,451
Ensembl chr12:60,416,463...60,435,450 		JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 involved_in IEA UniProt
TreeGrafter
Ensembl		 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:22,535,780...22,540,322
Ensembl chr 5:22,532,894...22,540,319 		JBrowse link
tetrahydrofolate interconversion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2A1 BCL2 related protein A1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:48,887,227...48,897,667
Ensembl chr 7:48,887,094...48,897,870 		JBrowse link
G DHFR dihydrofolate reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:89,230,660...89,255,830 JBrowse link
G DMGDH dimethylglycine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chr 2:87,791,827...87,867,189
Ensembl chr 2:87,791,943...87,866,679 		JBrowse link
G EPGN epithelial mitogen involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:70,266,867...70,301,250
Ensembl chr 8:70,292,467...70,300,149 		JBrowse link
G LOC102167410 5-formyltetrahydrofolate cyclo-ligase involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:48,717,518...48,873,492
Ensembl chr 7:48,717,851...48,873,455 		JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEA
IBA		 UniProt
Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000041 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:88,471,317...88,533,690
Ensembl chr 7:88,471,414...88,537,387 		JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like involved_in IEA
IBA		 UniProt
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000041 GO_REF:0000118 NCBI chr 1:15,140,929...15,330,265
Ensembl chr 1:15,140,899...15,329,986 		JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:68,819,171...68,833,641
Ensembl chr 3:68,818,119...68,833,600 		JBrowse link
G MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like involved_in ISO
IBA		 RGD
GO_Central		 PMID:21163947 GO_REF:0000033 RGD:7244288 NCBI chr 8:70,179,701...70,288,356
Ensembl chr 8:70,179,658...70,290,047 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase involved_in IEA
IBA		 UniProt
Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000041 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,637...71,881,820 		JBrowse link
G SARDH sarcosine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chr 1:273,230,357...273,295,170
Ensembl chr 1:273,230,375...273,294,621 		JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 involved_in IEA Ensembl
InterPro
UniProt
TreeGrafter		 GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 GO_REF:0000118 NCBI chr12:60,414,421...60,435,451
Ensembl chr12:60,416,463...60,435,450 		JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 involved_in IEA UniProt
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000041 GO_REF:0000107 NCBI chr 5:22,535,780...22,540,322
Ensembl chr 5:22,532,894...22,540,319 		JBrowse link
G TYMS thymidylate synthetase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:105,642,730...105,660,279
Ensembl chr 6:105,642,381...105,660,578 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17806
    metabolic process 10376
      cellular metabolic process 8638
        one-carbon metabolic process 39
          serine-isocitrate lyase pathway 0
          tetrahydrofolate interconversion 14
paths to the root