CA12 (carbonic anhydrase 12) - Rat Genome Database

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Gene: CA12 (carbonic anhydrase 12) Sus scrofa
Analyze
Symbol: CA12
Name: carbonic anhydrase 12
RGD ID: 13884589
Description: ENCODES a protein that exhibits carbonate dehydratase activity (inferred); zinc ion binding (inferred); INVOLVED IN chloride ion homeostasis (inferred); ASSOCIATED WITH Bloom syndrome (ortholog); colon cancer (ortholog); hypertrophic cardiomyopathy (ortholog); FOUND IN integral component of membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1108,649,271 - 108,710,651 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11108,649,277 - 108,710,658 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21119,822,275 - 119,904,112 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
CA12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1108,649,271 - 108,710,651 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11108,649,277 - 108,710,658 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21119,822,275 - 119,904,112 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CA12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1563,321,378 - 63,381,846 (-)EnsemblGRCh38hg38GRCh38
GRCh381563,321,378 - 63,381,846 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371563,613,577 - 63,674,045 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361561,402,783 - 61,461,128 (-)NCBINCBI36hg18NCBI36
Celera1540,494,364 - 40,552,718 (-)NCBI
Cytogenetic Map15q22.2NCBI
HuRef1540,438,444 - 40,496,766 (-)NCBIHuRef
CHM1_11563,732,628 - 63,793,404 (-)NCBICHM1_1
Car12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39966,619,026 - 66,674,127 (+)NCBIGRCm39mm39
GRCm39 Ensembl966,620,968 - 66,674,127 (+)Ensembl
GRCm38966,712,296 - 66,766,845 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl966,713,686 - 66,766,845 (+)EnsemblGRCm38mm10GRCm38
MGSCv37966,561,493 - 66,614,652 (+)NCBIGRCm37mm9NCBIm37
MGSCv36966,512,886 - 66,565,989 (+)NCBImm8
Celera963,948,029 - 64,000,964 (+)NCBICelera
Cytogenetic Map9CNCBI
Ca12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2867,274,739 - 67,330,428 (+)NCBI
Rnor_6.0 Ensembl872,405,748 - 72,460,240 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0872,405,770 - 72,461,425 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0872,071,988 - 72,127,646 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4871,017,732 - 71,070,729 (+)NCBIRGSC3.4rn4RGSC3.4
Celera866,660,144 - 66,713,076 (+)NCBICelera
Cytogenetic Map8q24NCBI
Ca12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545011,943,340 - 11,975,928 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545011,927,730 - 11,975,553 (+)NCBIChiLan1.0ChiLan1.0
CA12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11560,565,592 - 60,624,008 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1560,565,592 - 60,624,008 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01542,270,188 - 42,328,952 (-)NCBIMhudiblu_PPA_v0panPan3
CA12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13027,903,460 - 27,957,162 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3027,905,837 - 27,957,742 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3027,822,431 - 27,876,096 (-)NCBI
ROS_Cfam_1.03028,075,321 - 28,129,041 (-)NCBI
UMICH_Zoey_3.13028,012,749 - 28,066,343 (-)NCBI
UNSW_CanFamBas_1.03028,074,625 - 28,128,260 (-)NCBI
UU_Cfam_GSD_1.03028,311,867 - 28,365,995 (-)NCBI
Ca12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640106,028,826 - 106,081,389 (-)NCBI
SpeTri2.0NW_00493647123,876,889 - 23,929,720 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA12
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12620,162,706 - 20,221,680 (+)NCBI
ChlSab1.1 Ensembl2620,162,926 - 20,224,502 (+)Ensembl
Ca12
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247819,140,753 - 9,195,651 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 6 1 2 1
Low 4 3 3 5 21 1 3
Below cutoff 1 2 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000005044   ⟹   ENSSSCP00000004924
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1108,649,271 - 108,697,628 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000062560   ⟹   ENSSSCP00000053714
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1108,649,271 - 108,710,651 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000070413   ⟹   ENSSSCP00000068458
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1108,649,271 - 108,710,651 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000073832   ⟹   ENSSSCP00000068980
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1108,649,271 - 108,710,651 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000082294   ⟹   ENSSSCP00000064291
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1108,649,271 - 108,710,651 (+)Ensembl
RefSeq Acc Id: XM_021094163   ⟹   XP_020949822
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11108,649,277 - 108,710,658 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021094165   ⟹   XP_020949824
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11108,649,277 - 108,710,658 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020949822 (Get FASTA)   NCBI Sequence Viewer  
  XP_020949824 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020949822   ⟸   XM_021094163
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020949824   ⟸   XM_021094165
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSSSCP00000068980   ⟸   ENSSSCT00000073832
RefSeq Acc Id: ENSSSCP00000004924   ⟸   ENSSSCT00000005044
RefSeq Acc Id: ENSSSCP00000068458   ⟸   ENSSSCT00000070413
RefSeq Acc Id: ENSSSCP00000053714   ⟸   ENSSSCT00000062560
RefSeq Acc Id: ENSSSCP00000064291   ⟸   ENSSSCT00000082294
Protein Domains
Alpha-carbonic anhydrase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000004565 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000004924 UniProtKB/TrEMBL
  ENSSSCP00000053714 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000064291 UniProtKB/TrEMBL
  ENSSSCP00000068458 UniProtKB/TrEMBL
  ENSSSCP00000068980 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000005044 UniProtKB/TrEMBL
  ENSSSCT00000062560 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000070413 UniProtKB/TrEMBL
  ENSSSCT00000073832 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000082294 UniProtKB/TrEMBL
Gene3D-CATH 3.10.200.10 UniProtKB/TrEMBL
InterPro CA_dom UniProtKB/TrEMBL
  CA_dom_sf UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class_CS UniProtKB/TrEMBL
  Carbonic_anhydrase_CA12 UniProtKB/TrEMBL
NCBI Gene CA12 ENTREZGENE
PANTHER PTHR18952 UniProtKB/TrEMBL
  PTHR18952:SF19 UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/TrEMBL
PROSITE ALPHA_CA_1 UniProtKB/TrEMBL
  ALPHA_CA_2 UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
Superfamily-SCOP SSF51069 UniProtKB/TrEMBL
UniProt A0A287BC72_PIG UniProtKB/TrEMBL
  A0A480VHT3_PIG UniProtKB/TrEMBL
  A0A5G2QIM6_PIG UniProtKB/TrEMBL
  A0A5G2QUF0_PIG UniProtKB/TrEMBL
  F1S092_PIG UniProtKB/TrEMBL
VGNC ID VGNC:86097 ENTREZGENE