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ONTOLOGY REPORT - ANNOTATIONS


Term:tetrahydrofolate interconversion
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Accession:GO:0035999 term browser browse the term
Definition:The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesise other tetrahydrofolate molecules.
Synonyms:xref: MetaCyc:PWY-2201;   UniPathway:UPA00193



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tetrahydrofolate interconversion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhfr dihydrofolate reductase involved_in ISO (MGI:67444|PMID:360074) RGD PMID:360074 MGI:67444 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G Dmgdh dimethylglycine dehydrogenase IDA RGD PMID:6163778 RGD:7245485 NCBI chr 2:24,912,600...24,987,533
Ensembl chr 2:24,912,578...24,987,528
JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735
JBrowse link
G LOC680432 similar to methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 3:116,195,791...116,198,973 JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEA
ISS
ISO
IBA
GO_REF:0000041
GO_REF:0000024
(PMID:10828945), (PMID:1881876)
(MGI:5503248|PMID:23704330)
PMID:21873635
UniProt
RGD
PMID:1881876 PMID:10828945 PMID:23704330 PMID:21873635 GO_REF:0000024 GO_REF:0000041 MGI:5503248, RGD:13792537 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372
JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like involved_in IBA
IEA
PMID:21873635
GO_REF:0000041
UniProt PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like involved_in IDA
IEA
IBA
PMID:24733394
GO_REF:0000041
PMID:21873635
UniProt
RGD
PMID:21163947 PMID:24733394 PMID:21873635 GO_REF:0000041, RGD:7244288, RGD:150521648, RGD:13792537 NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112
JBrowse link
G Mthfr methylenetetrahydrofolate reductase involved_in IEA
ISO
IBA
GO_REF:0000041
UniProtKB:P53128 (PMID:10551815), (PMID:12673793), (PMID:25736335), (PMID:29891918)
PMID:21873635
UniProt
RGD
PMID:10551815 PMID:12673793 PMID:25736335 PMID:29891918 PMID:21873635 GO_REF:0000041, RGD:13792537 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Mthfs methenyltetrahydrofolate synthetase involved_in ISO
IBA
(PMID:12764149)
PMID:21873635
RGD PMID:12764149 PMID:21873635 RGD:13792537 NCBI chr 8:89,729,498...89,801,998
Ensembl chr 8:89,729,508...89,799,089
JBrowse link
G Sardh sarcosine dehydrogenase IDA RGD PMID:6163778 RGD:7245485 NCBI chr 3:10,510,553...10,575,342
Ensembl chr 3:10,510,553...10,573,874
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in IBA
ISO
IEA
PMID:21873635
MGI:1277989 (MGI:3849912|PMID:19513116)
GO_REF:0000041
(PMID:24698160)
RGD
UniProt
PMID:19513116 PMID:24698160 PMID:21873635 GO_REF:0000041 MGI:3849912, RGD:13792537 NCBI chr10:45,468,698...45,497,820
Ensembl chr10:45,468,700...45,497,820
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in IBA
ISO
IEA
PMID:21873635
MGI:98299 (MGI:3849912|PMID:19513116)
GO_REF:0000041
RGD
UniProt
PMID:19513116 PMID:21873635 PMID:21873635 GO_REF:0000041 MGI:3849912, RGD:13792537, RGD:13792537 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
JBrowse link
G Tyms thymidylate synthetase involved_in ISO (PMID:15093541)
(MGI:5300404|PMID:22057276)
RGD PMID:15093541 PMID:22057276 MGI:5300404 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      small molecule metabolic process 1804
        one-carbon metabolic process 41
          tetrahydrofolate interconversion 14
Path 2
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      organic substance metabolic process 11355
        organonitrogen compound metabolic process 6852
          cellular modified amino acid metabolic process 203
            folic acid-containing compound metabolic process 29
              tetrahydrofolate metabolic process 22
                tetrahydrofolate interconversion 14
paths to the root