CA2 (carbonic anhydrase 2) - Rat Genome Database

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Gene: CA2 (carbonic anhydrase 2) Sus scrofa
Analyze
Symbol: CA2
Name: carbonic anhydrase 2
RGD ID: 13964000
Description: ENCODES a protein that exhibits carbonate dehydratase activity (ortholog); INVOLVED IN carbon dioxide transport (ortholog); cellular response to fluid shear stress (ortholog); kidney development (ortholog); ASSOCIATED WITH adenocarcinoma (ortholog); Animal Disease Models (ortholog); autism spectrum disorder (ortholog); FOUND IN apical part of cell (ortholog); axon (ortholog); basolateral plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC100154873
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl451,193,755 - 51,211,259 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1451,194,686 - 51,211,436 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2456,157,606 - 56,174,354 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:14681463  


Genomics

Comparative Map Data
CA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl451,193,755 - 51,211,259 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1451,194,686 - 51,211,436 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2456,157,606 - 56,174,354 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl885,463,968 - 85,481,493 (+)EnsemblGRCh38hg38GRCh38
GRCh38885,464,007 - 85,481,493 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37886,376,236 - 86,393,722 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36886,563,383 - 86,580,973 (+)NCBINCBI36hg18NCBI36
Build 34886,563,497 - 86,580,973NCBI
Celera882,381,194 - 82,398,781 (+)NCBI
Cytogenetic Map8q21.2NCBI
HuRef881,870,322 - 81,887,902 (+)NCBIHuRef
CHM1_1886,427,817 - 86,445,411 (+)NCBICHM1_1
Car2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39314,951,329 - 14,965,830 (+)NCBIGRCm39mm39
GRCm39 Ensembl314,951,333 - 14,965,830 (+)Ensembl
GRCm38314,886,269 - 14,900,770 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl314,886,273 - 14,900,770 (+)EnsemblGRCm38mm10GRCm38
MGSCv37314,886,426 - 14,900,770 (+)NCBIGRCm37mm9NCBIm37
MGSCv36314,863,469 - 14,877,513 (+)NCBImm8
Celera314,899,001 - 14,912,886 (+)NCBICelera
Cytogenetic Map3A1NCBI
cM Map33.23NCBI
Car2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2286,741,625 - 86,756,766 (-)NCBI
Rnor_6.0 Ensembl288,097,720 - 88,113,029 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0288,097,740 - 88,112,868 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02107,871,654 - 107,886,782 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4288,077,095 - 88,092,223 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1288,022,060 - 88,037,185 (-)NCBI
Celera282,339,410 - 82,354,537 (-)NCBICelera
Cytogenetic Map2q23NCBI
Ca2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554173,386,087 - 3,402,363 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554173,388,110 - 3,402,798 (+)NCBIChiLan1.0ChiLan1.0
CA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1883,601,163 - 83,618,327 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl883,597,440 - 83,632,580 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0881,991,037 - 82,009,010 (+)NCBIMhudiblu_PPA_v0panPan3
CA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12931,959,225 - 31,975,309 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2931,935,172 - 31,980,579 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2932,190,440 - 32,197,007 (+)NCBI
ROS_Cfam_1.02932,108,070 - 32,124,176 (+)NCBI
UMICH_Zoey_3.12932,159,433 - 32,175,512 (+)NCBI
UNSW_CanFamBas_1.02932,180,668 - 32,196,793 (+)NCBI
UU_Cfam_GSD_1.02932,567,770 - 32,583,867 (+)NCBI
Ca2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530347,413,843 - 47,429,881 (-)NCBI
SpeTri2.0NW_004936544362,591 - 379,151 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1880,830,963 - 80,848,245 (+)NCBI
ChlSab1.1 Ensembl880,830,939 - 80,848,707 (+)Ensembl
Ca2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247446,168,030 - 6,183,407 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 6 15 2
Low 2 3 3 2 8 1 1
Below cutoff 1 4 2 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000006733   ⟹   ENSSSCP00000006550
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl451,193,755 - 51,211,259 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000041218   ⟹   ENSSSCP00000052106
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl451,193,755 - 51,210,211 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000074544   ⟹   ENSSSCP00000066647
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl451,193,755 - 51,210,511 (-)Ensembl
RefSeq Acc Id: XM_001927805   ⟹   XP_001927840
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1451,194,686 - 51,211,436 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_001927840 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_001927840   ⟸   XM_001927805
- UniProtKB: F1RXC2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000066647   ⟸   ENSSSCT00000074544
RefSeq Acc Id: ENSSSCP00000006550   ⟸   ENSSSCT00000006733
RefSeq Acc Id: ENSSSCP00000052106   ⟸   ENSSSCT00000041218
Protein Domains
Alpha-carbonic anhydrase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000006140 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070016297 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000006550 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000052106 UniProtKB/TrEMBL
  ENSSSCP00000066647 UniProtKB/TrEMBL
  ENSSSCP00070026731 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000006733 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000041218 UniProtKB/TrEMBL
  ENSSSCT00000074544 UniProtKB/TrEMBL
  ENSSSCT00070032052 UniProtKB/TrEMBL
Gene3D-CATH 3.10.200.10 UniProtKB/TrEMBL
InterPro CA_dom UniProtKB/TrEMBL
  CA_dom_sf UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class_CS UniProtKB/TrEMBL
KEGG Report ssc:100154873 UniProtKB/TrEMBL
NCBI Gene LOC100154873 ENTREZGENE
PANTHER PTHR18952 UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/TrEMBL
PROSITE ALPHA_CA_1 UniProtKB/TrEMBL
  ALPHA_CA_2 UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
Superfamily-SCOP SSF51069 UniProtKB/TrEMBL
UniProt A0A287B6M0_PIG UniProtKB/TrEMBL
  A0A4X1UA73_PIG UniProtKB/TrEMBL
  A0A5G2QRG3_PIG UniProtKB/TrEMBL
  F1RXC2 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:98746 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-03-10 CA2  carbonic anhydrase 2  LOC100154873  carbonic anhydrase 2  Symbol and/or name change 5135510 APPROVED