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ONTOLOGY REPORT - ANNOTATIONS


Term:one-carbon metabolic process
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Accession:GO:0006730 term browser browse the term
Definition:The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
Synonyms:exact_synonym: one carbon metabolism;   one-carbon transfer metabolic process;   one-carbon transfer metabolism
 alt_id: GO:0019753;   GO:0019754
 xref: UM-BBD_pathwayID:C1cyc


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one-carbon metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHCY adenosylhomocysteinase involved_in IEA UniProt GO_REF:0000043 NCBI chr17:37,726,084...37,744,378
Ensembl chr17:37,726,077...37,744,461
JBrowse link
G AHCYL1 adenosylhomocysteinase like 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 4:110,092,976...110,132,826
Ensembl chr 4:110,092,528...110,132,647
JBrowse link
G AHCYL2 adenosylhomocysteinase like 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr18:19,260,226...19,441,839
Ensembl chr18:19,260,226...19,441,928
JBrowse link
G ALDH1L1 aldehyde dehydrogenase 1 family member L1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 7:53,748,585...53,794,777
Ensembl chr 7:53,748,585...53,794,706
JBrowse link
G ALDH1L2 aldehyde dehydrogenase 1 family member L2 involved_in IEA UniProt GO_REF:0000043 NCBI chr 5:79,492,672...79,558,702
Ensembl chr 5:79,492,732...79,558,701
JBrowse link
G CA1 carbonic anhydrase 1 involved_in IBA
IEA
(PMID:21873635) GO_Central
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr 4:51,343,548...51,353,127
Ensembl chr 4:51,302,406...51,353,127
JBrowse link
G CA11 carbonic anhydrase 11 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:53,993,183...53,999,357
Ensembl chr 6:53,993,393...53,999,174
JBrowse link
G CA12 carbonic anhydrase 12 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:108,649,277...108,710,658
Ensembl chr 1:108,649,271...108,710,651
JBrowse link
G CA13 carbonic anhydrase 13 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:51,406,755...51,468,971
Ensembl chr 4:51,407,473...51,468,961
JBrowse link
G CA14 carbonic anhydrase 14 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:98,821,577...98,828,934
Ensembl chr 4:98,821,578...98,828,736
JBrowse link
G CA2 carbonic anhydrase 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:51,194,686...51,211,436
Ensembl chr 4:51,193,755...51,211,259
JBrowse link
G CA4 carbonic anhydrase 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:37,962,951...37,972,443
Ensembl chr12:37,962,943...37,972,509
JBrowse link
G CA5A carbonic anhydrase 5A involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:1,495,615...1,539,390
Ensembl chr 6:1,505,566...1,538,494
JBrowse link
G CA5B carbonic anhydrase 5B involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:12,295,393...12,332,283
Ensembl chr  X:12,224,159...12,365,025
JBrowse link
G CA6 carbonic anhydrase 6 involved_in IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr 6:69,447,662...69,468,819
Ensembl chr 6:69,447,439...69,468,821
JBrowse link
G CA7 carbonic anhydrase 7 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:27,548,647...27,563,966
Ensembl chr 6:27,548,706...27,563,861
JBrowse link
G CA8 carbonic anhydrase 8 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:73,047,867...73,172,215
Ensembl chr 4:73,047,847...73,141,991
JBrowse link
G DHFR dihydrofolate reductase involved_in IEA UniProt GO_REF:0000043 NCBI chr 2:89,230,660...89,255,830 JBrowse link
G FPGS folylpolyglutamate synthase involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:268,281,298...268,309,397
Ensembl chr 1:268,287,729...268,309,411
JBrowse link
G GNMT glycine N-methyltransferase involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
(PMID:21873635)
(MGI:3842675|PMID:17937387)
GO_Central
MGI
Ensembl
PMID:17937387 PMID:21873635 GO_REF:0000107 MGI:3842675 NCBI chr 7:38,038,359...38,041,218
Ensembl chr 7:38,038,358...38,041,218
JBrowse link
G MAT1A methionine adenosyltransferase 1A involved_in IEA UniProt GO_REF:0000043 NCBI chr14:82,109,405...82,126,487
Ensembl chr14:82,109,404...82,127,049
JBrowse link
G MAT2A methionine adenosyltransferase 2A involved_in IEA UniProt GO_REF:0000043 NCBI chr 3:59,220,203...59,225,097
Ensembl chr 3:59,211,157...59,225,261
JBrowse link
G MAT2B methionine adenosyltransferase 2B involved_in IEA UniProt GO_REF:0000043 NCBI chr16:60,255,541...60,274,228
Ensembl chr16:60,255,357...60,274,085
JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:25633902) RGD
BHF-UCL
PMID:14597174 PMID:25633902 RGD:1302361 NCBI chr 7:88,471,317...88,533,690
Ensembl chr 7:88,471,414...88,537,600
JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase involved_in IEA UniProt GO_REF:0000043 NCBI chr 3:68,819,171...68,833,641
Ensembl chr 3:68,819,612...68,853,067
JBrowse link
G MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like involved_in IEA UniProt GO_REF:0000043 NCBI chr 8:70,179,701...70,288,356
Ensembl chr 8:70,179,658...70,300,150
JBrowse link
G SFXN1 sideroflexin 1 acts_upstream_of ISS UniProt GO_REF:0000024 NCBI chr 2:82,025,799...82,057,629
Ensembl chr 2:82,025,815...82,057,564
JBrowse link
G SFXN3 sideroflexin 3 acts_upstream_of
involved_in
ISO
IEA
(PMID:30442778) UniProt
Ensembl
PMID:30442778 GO_REF:0000107 NCBI chr14:112,111,483...112,119,166
Ensembl chr14:112,111,567...112,119,162
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:60,414,421...60,435,451
Ensembl chr12:60,414,446...60,435,450
JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:22,535,780...22,540,322
Ensembl chr 5:22,532,894...22,540,321
JBrowse link
tetrahydrofolate interconversion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DMGDH dimethylglycine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chr 2:87,791,827...87,867,189
Ensembl chr 2:87,678,811...87,866,856
JBrowse link
G EPGN epithelial mitogen involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:70,266,867...70,301,250
Ensembl chr 8:70,179,658...70,300,150
JBrowse link
G FTCD formimidoyltransferase cyclodeaminase involved_in IEA UniProt GO_REF:0000041
G LOC102167410 5-formyltetrahydrofolate cyclo-ligase involved_in ISO (PMID:12764149) BHF-UCL PMID:12764149 NCBI chr 7:48,717,518...48,873,492 JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IBA
IEA
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000041 NCBI chr 7:88,471,317...88,533,690
Ensembl chr 7:88,471,414...88,537,600
JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like involved_in IBA
IEA
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000041 NCBI chr 1:15,140,929...15,330,265
Ensembl chr 1:15,140,898...15,329,966
JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:68,819,171...68,833,641
Ensembl chr 3:68,819,612...68,853,067
JBrowse link
G MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like involved_in IBA
ISO
(PMID:21873635) GO_Central
RGD
PMID:21163947 PMID:21873635 RGD:7244288 NCBI chr 8:70,179,701...70,288,356
Ensembl chr 8:70,179,658...70,300,150
JBrowse link
G MTHFR methylenetetrahydrofolate reductase involved_in IBA
IEA
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000041 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,636...71,881,820
JBrowse link
G SARDH sarcosine dehydrogenase ISO RGD PMID:6163778 RGD:7245485 NCBI chr 1:273,230,357...273,295,170
Ensembl chr 1:273,228,838...273,295,104
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 involved_in IEA
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000041 NCBI chr12:60,414,421...60,435,451
Ensembl chr12:60,414,446...60,435,450
JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 involved_in IBA
IEA
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000041 NCBI chr 5:22,535,780...22,540,322
Ensembl chr 5:22,532,894...22,540,321
JBrowse link
G TYMS thymidylate synthetase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:105,642,730...105,660,279
Ensembl chr 6:105,640,031...105,660,601
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 16534
    metabolic process 10398
      cellular metabolic process 9477
        one-carbon metabolic process 38
          serine-isocitrate lyase pathway 0
          tetrahydrofolate interconversion 13
paths to the root