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ONTOLOGY REPORT - ANNOTATIONS

Term:DNA unwinding involved in DNA replication
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Accession:GO:0006268 term browser browse the term
Definition:The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication.
Comment:Note that this term refers to a geometric change in DNA conformation, and should not be confused with 'DNA topological change ; GO:0006265'.
Synonyms:related_synonym: DNA unwinding during replication;   DNA unwinding factor


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DNA unwinding involved in DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312 		JBrowse link
G Cdc45 cell division cycle 45 involved_in ISO (PMID:22474384) RGD PMID:22474384 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619 		JBrowse link
G Gins1 GINS complex subunit 1 involved_in ISO (PMID:22474384) RGD PMID:22474384 NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936 		JBrowse link
G Gins2 GINS complex subunit 2 involved_in ISO (PMID:22474384) RGD PMID:22474384 NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339 		JBrowse link
G Gins3 GINS complex subunit 3 involved_in ISO (PMID:22474384) RGD PMID:22474384 NCBI chr19:9,420,085...9,428,621
Ensembl chr19:9,420,086...9,428,687 		JBrowse link
G Gins4 GINS complex subunit 4 involved_in ISO
IEA		 (PMID:22474384)
GO_REF:0000107		 RGD
Ensembl		 PMID:22474384 GO_REF:0000107 NCBI chr16:68,787,572...68,799,938
Ensembl chr16:68,767,339...68,802,273 		JBrowse link
G Mcm2 minichromosome maintenance complex component 2 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:22474384)
GO_REF:0000033
(PMID:10531422)		 RGD
GO_Central		 PMID:10531422 PMID:22474384 GO_REF:0000033 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847 		JBrowse link
G Mcm3 minichromosome maintenance complex component 3 involved_in ISO (PMID:22474384) RGD PMID:22474384 NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314 		JBrowse link
G Mcm4 minichromosome maintenance complex component 4 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:22474384)
GO_REF:0000033
PR:P97311|PR:Q61881 (PMID:15917436)		 RGD
GO_Central		 PMID:15917436 PMID:22474384 GO_REF:0000033 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144 		JBrowse link
G Mcm5 minichromosome maintenance complex component 5 involved_in ISO (PMID:22474384) RGD PMID:22474384 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389 		JBrowse link
G Mcm6 minichromosome maintenance complex component 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:22474384)
PR:P49717|PR:Q61881 (PMID:15917436)		 Ensembl
RGD		 PMID:15917436 PMID:22474384 GO_REF:0000107 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960 		JBrowse link
G Mcm7 minichromosome maintenance complex component 7 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:22474384)
GO_REF:0000033
PR:P49717|PR:P97311 (PMID:15917436)		 RGD
GO_Central		 PMID:15917436 PMID:22474384 GO_REF:0000033 NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063 		JBrowse link
G Pura purine rich element binding protein A involved_in ISO (PMID:15777841) RGD PMID:15777841 NCBI chr18:27,885,071...27,905,509
Ensembl chr18:27,884,556...27,905,513 		JBrowse link
G Rad51 RAD51 recombinase involved_in ISO (PMID:7988572) RGD PMID:7988572 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035 		JBrowse link
G Recql RecQ like helicase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:175,308,337...175,332,965
Ensembl chr 4:175,304,117...175,332,945 		JBrowse link
G Recql4 RecQ like helicase 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619 		JBrowse link
G Recql5 RecQ like helicase 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:101,126,544...101,165,739
Ensembl chr10:101,126,547...101,165,652 		JBrowse link
G Ssbp1 single stranded DNA binding protein 1 involved_in ISO
IEA		 (PMID:26446790)
GO_REF:0000107		 RGD
Ensembl		 PMID:26446790 GO_REF:0000107 NCBI chr 4:69,266,024...69,276,135
Ensembl chr 4:69,266,102...69,276,135 		JBrowse link
G Twnk twinkle mtDNA helicase involved_in
acts_upstream_of_or_within		 ISO (PMID:15167897)
(PMID:11431692)		 RGD PMID:11431692 PMID:15167897 NCBI chr 1:243,867,568...243,874,802
Ensembl chr 1:243,868,330...243,874,802 		JBrowse link
G Wrn WRN RecQ like helicase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:58,763,517...58,898,604
Ensembl chr16:58,763,504...58,895,450 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    metabolic process 12288
      macromolecule metabolic process 10146
        nucleic acid metabolic process 5148
          DNA metabolic process 960
            DNA replication 272
              DNA-templated DNA replication 161
                DNA unwinding involved in DNA replication 20
                  cell cycle DNA replication DNA unwinding + 0
Path 2
Term Annotations click to browse term
  biological_process 20115
    cellular process 18525
      cellular component organization or biogenesis 7044
        cellular component organization 6793
          organelle organization 3691
            chromosome organization 583
              DNA conformation change 94
                DNA geometric change 84
                  DNA duplex unwinding 77
                    DNA unwinding involved in DNA replication 20
                      cell cycle DNA replication DNA unwinding + 0
paths to the root