Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:cardiac conduction system development
go back to main search page
Accession:GO:0003161 term browser browse the term
Definition:The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat.
Synonyms:exact_synonym: cardiac impulse conducting system development;   heart conduction system development


show annotations for term's descendants           Sort by:
cardiac conduction system development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (MGI:3653945|PMID:16037571) RGD PMID:16037571 MGI:3653945 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Cdc42 cell division cycle 42 acts_upstream_of_or_within ISO MGI:97350 (PMID:21690310) RGD PMID:21690310 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Gja5 gap junction protein, alpha 5 acts_upstream_of_or_within ISO MGI:2445466 (PMID:18599871), (PMID:22203979) RGD PMID:18599871 PMID:22203979 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Mir1 microRNA 1 acts_upstream_of_or_within ISO (PMID:17397913) RGD PMID:17397913 NCBI chr18:1,887,537...1,887,623 JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within		 ISO (PMID:27207958)
MGI:106211 (PMID:21690310)
(PMID:15109497)		 RGD PMID:15109497 PMID:21690310 PMID:27207958 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Nrg1 neuregulin 1 acts_upstream_of_or_within ISO (PMID:12149465) RGD PMID:12149465 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
atrioventricular bundle cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irx3 iroquois homeobox 3 involved_in ISO (MGI:6101691|PMID:26786475) RGD PMID:26786475 MGI:6101691 NCBI chr19:15,211,882...15,215,317
Ensembl chr19:15,211,878...15,215,317 		JBrowse link
G Tbx3 T-box transcription factor 3 acts_upstream_of_or_within ISO MGI:3710254 (PMID:18467625) RGD PMID:18467625 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708 		JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3051695|PMID:15289437)		 Ensembl
RGD		 PMID:15289437 GO_REF:0000107 MGI:3051695 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885 		JBrowse link
atrioventricular node cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (MGI:3822612|PMID:17998461) RGD PMID:17998461 MGI:3822612 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Maml1 mastermind-like transcriptional coactivator 1 involved_in ISO (MGI:5000164|PMID:21266778) RGD PMID:21266778 MGI:5000164 NCBI chr10:34,588,639...34,623,024
Ensembl chr10:34,588,646...34,623,338 		JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3042511 (PMID:19546853)		 Ensembl
RGD		 PMID:19546853 GO_REF:0000107 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3051695|PMID:15289437)		 Ensembl
RGD		 PMID:15289437 GO_REF:0000107 MGI:3051695 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885 		JBrowse link
atrioventricular node cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 acts_upstream_of_or_within ISO MGI:6358100 (PMID:29666184) RGD PMID:29666184 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603 		JBrowse link
atrioventricular node cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3042511 (PMID:15109497)		 Ensembl
RGD		 PMID:15109497 GO_REF:0000107 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Tbx5 T-box transcription factor 5 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3051695|PMID:15289437)		 Ensembl
RGD		 PMID:15289437 GO_REF:0000107 MGI:3051695 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885 		JBrowse link
atrioventricular node development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-5 NK2 homeobox 5 involved_in ISO (MGI:3829107|PMID:18689573) RGD PMID:18689573 MGI:3829107 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:5000164|PMID:21266778) RGD PMID:21266778 MGI:5000164 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
bundle of His development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Id2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO MGI:2384134 (PMID:17604724) RGD PMID:17604724 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:102541 (PMID:17604724)		 Ensembl
RGD		 PMID:17604724 GO_REF:0000107 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
G Tbx5 T-box transcription factor 5 involved_in
acts_upstream_of_or_within		 ISO (MGI:5449667|PMID:22728936)
MGI:97350 (PMID:17604724)		 RGD PMID:17604724 PMID:22728936 MGI:5449667 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885 		JBrowse link
His-Purkinje system cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irx3 iroquois homeobox 3 involved_in ISO (MGI:6101691|PMID:26786475) RGD PMID:26786475 MGI:6101691 NCBI chr19:15,211,882...15,215,317
Ensembl chr19:15,211,878...15,215,317 		JBrowse link
Purkinje myocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dsg2 desmoglein 2 involved_in ISO (PMID:16505173) RGD PMID:16505173 NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156 		JBrowse link
G Irx3 iroquois homeobox 3 involved_in ISO (MGI:6101691|PMID:26786475) RGD PMID:26786475 MGI:6101691 NCBI chr19:15,211,882...15,215,317
Ensembl chr19:15,211,878...15,215,317 		JBrowse link
Purkinje myocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkx2-5 NK2 homeobox 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857618 (PMID:17250822)		 Ensembl
RGD		 PMID:17250822 GO_REF:0000107 NCBI chr10:16,340,428...16,347,004
Ensembl chr10:16,344,159...16,346,934 		JBrowse link
sinoatrial node cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bves blood vessel epicardial substance acts_upstream_of_or_within ISO MGI:2385915 (PMID:22354168) RGD PMID:22354168 NCBI chr20:48,819,241...48,860,282
Ensembl chr20:48,822,308...48,857,472 		JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in ISO
IEA		 (MGI:5688210|PMID:26193633)
GO_REF:0000107		 RGD
Ensembl		 PMID:26193633 GO_REF:0000107 MGI:5688210 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Popdc2 popeye domain containing 2 acts_upstream_of_or_within ISO MGI:3773727 (PMID:22354168) RGD PMID:22354168 NCBI chr11:62,351,843...62,398,688
Ensembl chr11:62,374,759...62,390,756 		JBrowse link
G Shox2 SHOX homeobox 2 involved_in ISO
IEA		 (MGI:5285465|PMID:21640717)
GO_REF:0000107		 RGD
Ensembl		 PMID:21640717 GO_REF:0000107 MGI:5285465 NCBI chr 2:151,217,049...151,227,180
Ensembl chr 2:151,217,552...151,227,143 		JBrowse link
G Tbx18 T-box transcription factor 18 involved_in ISO (PMID:23242162) RGD PMID:23242162 NCBI chr 8:88,652,054...88,680,081
Ensembl chr 8:88,652,054...88,680,058 		JBrowse link
G Tbx3 T-box transcription factor 3 involved_in
acts_upstream_of_or_within		 ISO (PMID:22130515)
MGI:3710254 (PMID:19096026)		 RGD PMID:19096026 PMID:22130515 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708 		JBrowse link
sinoatrial node cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (PMID:18297060) RGD PMID:18297060 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875 		JBrowse link
sinoatrial node cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbx18 T-box transcription factor 18 involved_in ISO (PMID:23242162) RGD PMID:23242162 NCBI chr 8:88,652,054...88,680,081
Ensembl chr 8:88,652,054...88,680,058 		JBrowse link
sinoatrial node development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata6 GATA binding protein 6 involved_in IEA
ISO		 GO_REF:0000107
MGI:2177784 (PMID:33443158)		 Ensembl
RGD		 PMID:33443158 GO_REF:0000107 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Shox2 SHOX homeobox 2 involved_in ISO (MGI:3836832|PMID:19166829) RGD PMID:19166829 MGI:3836832 NCBI chr 2:151,217,049...151,227,180
Ensembl chr 2:151,217,552...151,227,143 		JBrowse link
G Tbx18 T-box transcription factor 18 acts_upstream_of_or_within ISO MGI:3714982 (PMID:19096026) RGD PMID:19096026 NCBI chr 8:88,652,054...88,680,081
Ensembl chr 8:88,652,054...88,680,058 		JBrowse link
G Tbx5 T-box transcription factor 5 involved_in ISO
IEA		 (MGI:2150876|PMID:11572777)
GO_REF:0000107		 RGD
Ensembl		 PMID:11572777 GO_REF:0000107 MGI:2150876 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    developmental process 7008
      anatomical structure development 6530
        animal organ development 3676
          heart development 744
            cardiac muscle tissue development 293
              cardiac conduction system development 21
                His-Purkinje system development + 6
                atrioventricular node development + 6
                sinoatrial node development + 9
Path 2
Term Annotations click to browse term
  biological_process 20115
    developmental process 7008
      anatomical structure development 6530
        multicellular organism development 5268
          system development 4550
            circulatory system development 1373
              heart development 744
                cardiac muscle tissue development 293
                  cardiac conduction system development 21
                    His-Purkinje system development + 6
                    atrioventricular node development + 6
                    sinoatrial node development + 9
paths to the root