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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:quinalphos
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Accession:CHEBI:8712 term browser browse the term
Definition:An organothiophosphate insecticide that has formula C12H15N2O3PS.
Synonyms:exact_synonym: O,O-diethyl O-quinoxalin-2-yl phosphorothioate
 related_synonym: Bayrusil;   Diethyl O-(2-quinoxalyl) phosphorothioate;   Diethyl O-(quinoxalin-2-yl) thiophosphate;   Formula=C12H15N2O3PS;   InChI=1S/C12H15N2O3PS/c1-3-15-18(19,16-4-2)17-12-9-13-10-7-5-6-8-11(10)14-12/h5-9H,3-4H2,1-2H3;   InChIKey=JYQUHIFYBATCCY-UHFFFAOYSA-N;   O,O-diethyl O-quinoxalin-2-yl thiophosphate;   Phosphorothioic acid, O,O-diethyl O-(2-quinoxalinyl) ester;   SMILES=CCOP(=S)(OCC)Oc1cnc2ccccc2n1
 xref: CAS:13593-03-8;   KEGG:C11030
 xref_mesh: MESH:C009145
 xref: PPDB:576


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quinalphos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO quinalphos binds to and results in increased activity of AHR protein CTD PMID:18835618 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ar androgen receptor multiple interactions ISO Dihydrotestosterone inhibits the reaction [quinalphos results in increased activity of AR protein] CTD PMID:15064155 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Bche butyrylcholinesterase decreases activity
multiple interactions
ISO quinalphos results in decreased activity of BCHE protein
pralidoxime inhibits the reaction [quinalphos results in decreased activity of BCHE protein]
CTD PMID:24052565 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Cat catalase multiple interactions
decreases activity
ISO Plant Extracts inhibits the reaction [quinalphos results in decreased activity of CAT protein] CTD PMID:24581381 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases expression
multiple interactions
ISO quinalphos results in decreased expression of CYP26B1 mRNA
Plant Extracts inhibits the reaction [quinalphos results in decreased expression of CYP26B1 mRNA]
CTD PMID:24581381 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615
JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO quinalphos results in increased activity of ESR1 protein CTD PMID:15064155 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 increases activity ISO quinalphos results in increased activity of ESR2 protein CTD PMID:15064155 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
affects activity
EXP [Monocrotophos co-treated with quinalphos] affects the activity of G6PD protein
quinalphos affects the activity of G6PD protein
CTD PMID:24248738 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
affects activity
EXP [Monocrotophos co-treated with quinalphos] affects the activity of GSR protein
quinalphos affects the activity of GSR protein
CTD PMID:24248738 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 multiple interactions
decreases expression
ISO Plant Extracts inhibits the reaction [quinalphos results in decreased expression of HSD3B3 mRNA] CTD PMID:24581381 NCBI chr 2:200,756,557...200,762,492
Ensembl chr 2:200,585,748...200,762,492
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO quinalphos binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
decreases expression
ISO Plant Extracts inhibits the reaction [quinalphos results in decreased expression of STAR mRNA]; Plant Extracts inhibits the reaction [quinalphos results in decreased expression of STAR protein]
quinalphos results in decreased expression of STAR mRNA; quinalphos results in decreased expression of STAR protein
CTD PMID:24581381 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      application 19393
        agrochemical 14436
          quinalphos 12
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic molecule 19488
                              organic cyclic compound 19285
                                organic heterocyclic compound 18410
                                  organic heteropolycyclic compound 17824
                                    organic heterobicyclic compound 16744
                                      mancude organic heterobicyclic parent 5190
                                        naphthyridine 765
                                          quinoxaline 373
                                            quinoxaline derivative 373
                                              hydroxyquinoxaline 12
                                                quinoxalin-2-ol 12
                                                  quinalphos 12
paths to the root

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