Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:quinalphos
go back to main search page
Accession:CHEBI:8712 term browser browse the term
Definition:An organothiophosphate insecticide that has formula C12H15N2O3PS.
Synonyms:exact_synonym: O,O-diethyl O-quinoxalin-2-yl phosphorothioate
 related_synonym: Bayrusil;   Diethyl O-(2-quinoxalyl) phosphorothioate;   Diethyl O-(quinoxalin-2-yl) thiophosphate;   Formula=C12H15N2O3PS;   InChI=1S/C12H15N2O3PS/c1-3-15-18(19,16-4-2)17-12-9-13-10-7-5-6-8-11(10)14-12/h5-9H,3-4H2,1-2H3;   InChIKey=JYQUHIFYBATCCY-UHFFFAOYSA-N;   O,O-diethyl O-quinoxalin-2-yl thiophosphate;   Phosphorothioic acid, O,O-diethyl O-(2-quinoxalinyl) ester;   SMILES=CCOP(=S)(OCC)Oc1cnc2ccccc2n1
 xref: CAS:13593-03-8;   KEGG:C11030
 xref_mesh: MESH:C009145
 xref: PPDB:576



show annotations for term's descendants           Sort by:
 
quinalphos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity
multiple interactions
EXP quinalphos results in decreased activity of ACHE protein
Arsenic promotes the reaction [quinalphos results in decreased activity of ACHE protein]; quinalphos promotes the reaction [Arsenic results in decreased activity of ACHE protein]
CTD PMID:32270456 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO quinalphos binds to and results in increased activity of AHR protein CTD PMID:18835618 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Alb albumin multiple interactions EXP [Arsenic co-treated with quinalphos] results in decreased expression of ALB protein CTD PMID:32270456 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Ar androgen receptor multiple interactions ISO Dihydrotestosterone inhibits the reaction [quinalphos results in increased activity of AR protein] CTD PMID:15064155 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Bche butyrylcholinesterase decreases activity
multiple interactions
ISO quinalphos results in decreased activity of BCHE protein
pralidoxime inhibits the reaction [quinalphos results in decreased activity of BCHE protein]
CTD PMID:24052565 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Cat catalase multiple interactions
decreases activity
ISO
EXP
Plant Extracts inhibits the reaction [quinalphos results in decreased activity of CAT protein]
[Arsenic co-treated with quinalphos] results in decreased activity of CAT protein
CTD PMID:24581381 PMID:32270456 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression ISO quinalphos results in increased expression of CYP19A1 mRNA CTD PMID:34014595 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases expression
multiple interactions
ISO quinalphos results in decreased expression of CYP26B1 mRNA
Plant Extracts inhibits the reaction [quinalphos results in decreased expression of CYP26B1 mRNA]
CTD PMID:24581381 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO quinalphos results in increased activity of ESR1 protein CTD PMID:15064155 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 increases activity ISO quinalphos results in increased activity of ESR2 protein CTD PMID:15064155 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
affects activity
EXP [Monocrotophos co-treated with quinalphos] affects the activity of G6PD protein
quinalphos affects the activity of G6PD protein
CTD PMID:24248738 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
affects activity
EXP [Arsenic co-treated with quinalphos] results in decreased activity of GSR protein; [Monocrotophos co-treated with quinalphos] affects the activity of GSR protein
quinalphos results in decreased activity of GSR protein
quinalphos affects the activity of GSR protein
CTD PMID:24248738 PMID:32270456 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 multiple interactions
decreases expression
ISO Plant Extracts inhibits the reaction [quinalphos results in decreased expression of HSD3B3 mRNA] CTD PMID:24581381 NCBI chr 2:186,138,044...186,144,024
Ensembl chr 2:186,138,044...186,144,033
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO quinalphos binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
decreases expression
ISO Plant Extracts inhibits the reaction [quinalphos results in decreased expression of STAR mRNA]; Plant Extracts inhibits the reaction [quinalphos results in decreased expression of STAR protein]
quinalphos results in decreased expression of STAR mRNA; quinalphos results in decreased expression of STAR protein
CTD PMID:24581381 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19757
      application 19467
        agrochemical 15039
          quinalphos 15
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19807
      composite particle 19807
        hadron 19807
          baryon 19807
            nucleon 19807
              atomic nucleus 19807
                atom 19807
                  main group element atom 19704
                    p-block element atom 19704
                      carbon group element atom 19626
                        carbon atom 19616
                          organic molecular entity 19616
                            organic molecule 19556
                              organic cyclic compound 19347
                                organic heterocyclic compound 18580
                                  organic heteropolycyclic compound 18057
                                    organic heterobicyclic compound 16867
                                      mancude organic heterobicyclic parent 5408
                                        naphthyridine 797
                                          quinoxaline 385
                                            quinoxaline derivative 385
                                              hydroxyquinoxaline 15
                                                quinoxalin-2-ol 15
                                                  quinalphos 15
paths to the root