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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621747
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gsr
Name: glutathione-disulfide reductase
Acc ID: CHEBI:8712
Term: quinalphos
Definition: An organothiophosphate insecticide that has formula C12H15N2O3PS.
Chemical ID: MESH:C009145
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gsraffects activityEXP 6480464CTDquinalphos affects the activity of GSR proteinPMID:24248738
Gsrdecreases activityEXP 6480464CTDquinalphos results in decreased activity of GSR proteinPMID:32270456
Gsrmultiple interactionsEXP 6480464CTD[Arsenic co-treated with quinalphos] results in decreased activity of GSR protein; [Monocrotophos co-treated with quinalphos] affects the activity of GSR proteinPMID:24248738 PMID:32270456
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