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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:naphthyridine
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Accession:CHEBI:36624 term browser browse the term
Definition:Any one of eight organic heterobicyclic compounds that have a naphthalene skeleton in which two of the carbons are replaced by nitrogens. A 'closed' class.
Synonyms:related_synonym: Formula=C8H6N2
 xref: Wikipedia:Naphthyridine



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6,7-dimethoxy-2-phenylquinoxaline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [PDGFB protein results in increased phosphorylation of AKT1 protein] CTD PMID:25896968 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein] CTD PMID:25896968 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein] CTD PMID:25896968 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions ISO 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [Nicotine results in increased expression of PDGFB mRNA]; 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [Nicotine results in increased secretion of PDGFB protein]; 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [PDGFB protein results in increased phosphorylation of AKT1 protein]; 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]; 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]; 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [PDGFB protein results in increased phosphorylation of PDGFRB protein]; 6,7-dimethoxy-2-phenylquinoxaline results in decreased susceptibility to [PDGFB protein binds to PDGFB protein] CTD PMID:16149045 PMID:23457620 PMID:25896968 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions ISO 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [Nicotine results in increased expression of PDGFRB protein]; 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [PDGFB protein results in increased phosphorylation of PDGFRB protein] CTD PMID:16149045 PMID:25896968 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843
JBrowse link
6-Cyano-7-nitroquinoxaline-2,3-dione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco2 aconitase 2 multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Kainic Acid results in decreased activity of ACO2 protein] CTD PMID:11520895 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Pilocarpine results in increased expression of BDNF mRNA alternative form] CTD PMID:15183516 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Casp3 caspase 3 multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid inhibits the reaction [Phencyclidine results in increased activity of CASP3 protein]] CTD PMID:24995437 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Capsaicin results in increased expression of FOS] CTD PMID:10401552 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein] CTD PMID:21863293 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione results in increased expression of and results in increased localization of GRIA1 protein CTD PMID:19674091 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione results in increased expression of and results in increased localization of GRIA2 protein CTD PMID:19674091 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP
6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein]
6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]
CTD PMID:15385614 PMID:19850060 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO
EXP
6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK3 protein]
6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]
CTD PMID:15385614 PMID:19850060 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nefl neurofilament light chain multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFL protein]; 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [N-Methylaspartate results in decreased expression of NEFL mRNA]; 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Rotenone results in decreased expression of NEFL mRNA] CTD PMID:21863293 PMID:31969611 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
JBrowse link
G Nefm neurofilament medium chain multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFM protein] CTD PMID:21863293 NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755
JBrowse link
G Sct secretin multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [SCT protein results in increased secretion of gamma-Aminobutyric Acid] CTD PMID:15963647 NCBI chr 1:196,382,941...196,383,635
Ensembl chr 1:196,382,856...196,383,658
JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [L 703606 results in increased activity of TAC1 protein] CTD PMID:14985054 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Vim vimentin multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [diphenylditelluride results in decreased phosphorylation of VIM protein] CTD PMID:21863293 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
brimonidine tartrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A multiple interactions ISO
EXP
Brimonidine Tartrate inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; Brimonidine Tartrate promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA2A protein]; Phenylephrine promotes the reaction [Brimonidine Tartrate binds to and results in increased activity of ADRA2A protein]; Prazosin inhibits the reaction [Phenylephrine promotes the reaction [Brimonidine Tartrate binds to and results in increased activity of ADRA2A protein]]; Yohimbine inhibits the reaction [Brimonidine Tartrate promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA2A protein]] CTD PMID:8397342 PMID:10742289 PMID:12208771 PMID:12598592 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
JBrowse link
G Agt angiotensinogen multiple interactions EXP 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; bisindolylmaleimide I inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; bisindolylmaleimide I inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]; Brimonidine Tartrate promotes the reaction [AGT protein results in increased activity of RHOA protein]; diphenyleneiodonium inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; diphenyleneiodonium inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]] CTD PMID:18250367 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO Brimonidine Tartrate inhibits the reaction [CFTR protein affects the transport of Chlorides] CTD PMID:12598592 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation EXP Brimonidine Tartrate results in increased phosphorylation of CREB1 protein CTD PMID:17680988 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Prkca protein kinase C, alpha affects localization
multiple interactions
EXP Brimonidine Tartrate affects the localization of PRKCA protein
Nitric Oxide deficiency promotes the reaction [Brimonidine Tartrate affects the localization of PRKCA protein]
CTD PMID:12388232 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcd protein kinase C, delta affects localization
multiple interactions
EXP Brimonidine Tartrate affects the localization of PRKCD protein
Nitric Oxide deficiency inhibits the reaction [Brimonidine Tartrate affects the localization of PRKCD protein]
CTD PMID:12388232 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Rhoa ras homolog family member A multiple interactions EXP 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; bisindolylmaleimide I inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; Brimonidine Tartrate promotes the reaction [AGT protein results in increased activity of RHOA protein]; diphenyleneiodonium inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]] CTD PMID:18250367 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Brimonidine Tartrate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
Carbadox term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP Carbadox results in increased expression of CDKN1A mRNA; Carbadox results in increased expression of CDKN1A protein CTD PMID:26558467 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP Carbadox results in increased expression of MDM2 mRNA CTD PMID:26558467 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression EXP Carbadox results in decreased expression of MKI67 protein CTD PMID:26558467 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression EXP Carbadox results in decreased expression of TOP2A protein CTD PMID:26558467 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
cyclazosin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1b adrenoceptor alpha 1B multiple interactions EXP cyclazosin binds to and results in decreased activity of ADRA1B protein CTD PMID:15951348 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
JBrowse link
enoxacin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
affects binding
decreases activity
ISO
EXP
Enoxacin inhibits the reaction [CYP1A2 protein affects the metabolism of Fluvoxamine]; Enoxacin inhibits the reaction [CYP1A2 protein results in increased metabolism of Tacrine]; NADP promotes the reaction [Enoxacin inhibits the reaction [CYP1A2 protein results in increased metabolism of Tacrine]]
Enoxacin inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin]
Enoxacin binds to CYP1A2 protein
Enoxacin results in decreased activity of CYP1A2 protein
CTD PMID:7946932 PMID:8905919 PMID:15905806 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Enoxacin inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 affects binding ISO Enoxacin binds to KCNH2 protein CTD PMID:34058295 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions ISO 7-nitroindazole inhibits the reaction [[Enoxacin co-treated with fenbufen] results in increased activity of NOS1 protein]; [Enoxacin co-treated with fenbufen] results in increased activity of NOS1 protein CTD PMID:9623721 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
MK-2206 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions
decreases expression
ISO [gamma-mangostin co-treated with MK 2206] results in decreased expression of ACTA2 protein; MK 2206 inhibits the reaction [Radon results in increased expression of ACTA2 protein]
MK 2206 results in decreased expression of ACTA2 protein
CTD PMID:30502394 PMID:32949624 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Agt angiotensinogen multiple interactions ISO MK 2206 inhibits the reaction [AGT protein modified form results in increased secretion of IL6 protein]; MK 2206 inhibits the reaction [AGT protein modified form results in increased secretion of TNF protein] CTD PMID:30354818 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
increases phosphorylation
multiple interactions
ISO
EXP
MK 2206 results in decreased phosphorylation of AKT1 protein
MK 2206 results in increased phosphorylation of AKT1 protein
[gamma-mangostin co-treated with MK 2206] results in decreased phosphorylation of AKT1 protein; [PD 0325901 co-treated with MK 2206] results in increased phosphorylation of AKT1 protein; MK 2206 inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of AKT1 protein]; MK 2206 inhibits the reaction [PNPLA2 protein results in increased phosphorylation of AKT1 protein]; MK 2206 results in decreased phosphorylation of and results in decreased activity of AKT1 protein; romidepsin inhibits the reaction [[PD 0325901 co-treated with MK 2206] results in increased phosphorylation of AKT1 protein]
MK 2206 inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of and results in increased expression of AKT1 protein]; MK 2206 inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]]
LEPR affects the reaction [MK 2206 results in decreased phosphorylation of AKT1 protein]
CTD PMID:22885370 PMID:22949526 PMID:24685774 PMID:25597859 PMID:27634878 More... NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt1s1 AKT1 substrate 1 decreases phosphorylation
multiple interactions
ISO MK 2206 results in decreased phosphorylation of AKT1S1 protein
[STO 609 co-treated with MK 2206] results in decreased phosphorylation of AKT1S1 protein
CTD PMID:28634229 NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO MK 2206 inhibits the reaction [Cadmium Chloride results in increased expression of ATF4] CTD PMID:24057571 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO MK 2206 inhibits the reaction [Dexamethasone results in increased phosphorylation of BAD protein] CTD PMID:30878453 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions ISO [PD 0325901 co-treated with MK 2206] results in increased expression of BAK1 protein; [romidepsin co-treated with MK 2206] results in increased expression of BAK1 protein; [romidepsin co-treated with PD 0325901 co-treated with MK 2206] results in increased expression of BAK1 protein CTD PMID:27634878 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bcl2l11 BCL2 like 11 multiple interactions ISO [PD 0325901 co-treated with MK 2206] results in increased expression of BCL2L11 protein; [romidepsin co-treated with MK 2206] results in increased expression of BCL2L11 protein; [romidepsin co-treated with PD 0325901 co-treated with MK 2206] results in increased expression of BCL2L11 protein CTD PMID:27634878 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [PD 0325901 co-treated with MK 2206] results in increased expression of BID mRNA; [PD 0325901 co-treated with MK 2206] results in increased expression of BID protein modified form CTD PMID:28691888 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
ISO MK 2206 results in increased cleavage of CASP3 protein
MK 2206 inhibits the reaction [Dexamethasone results in increased cleavage of CASP3 protein]
[MK 2206 co-treated with platycodin D] results in increased activity of CASP3 protein; MK 2206 inhibits the reaction [Soot analog results in increased expression of CASP3 protein]
CTD PMID:22885370 PMID:27897231 PMID:30240709 PMID:30878453 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions ISO [MK 2206 co-treated with platycodin D] results in increased activity of CASP7 protein CTD PMID:27897231 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp9 caspase 9 multiple interactions ISO MK 2206 inhibits the reaction [Soot analog results in increased expression of CASP9 protein] CTD PMID:30240709 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cdh1 cadherin 1 multiple interactions
increases expression
ISO [MK 2206 co-treated with U 0126] results in increased expression of CDH1 mRNA
MK 2206 inhibits the reaction [Particulate Matter results in decreased expression of CDH1 protein]; MK 2206 inhibits the reaction [Radon results in decreased expression of CDH1 protein]
MK 2206 results in increased expression of CDH1 mRNA
CTD PMID:30723155 PMID:32687961 PMID:32949624 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO MK 2206 inhibits the reaction [Radon results in increased expression of CDH2 protein] CTD PMID:32949624 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Egfr epidermal growth factor receptor increases expression
multiple interactions
ISO MK 2206 results in increased expression of EGFR protein
platycodin D inhibits the reaction [MK 2206 results in increased expression of EGFR protein]
CTD PMID:27897231 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 decreases phosphorylation
multiple interactions
ISO MK 2206 results in decreased phosphorylation of EIF4EBP1 protein
[platycodin D co-treated with MK 2206] results in decreased phosphorylation of EIF4EBP1 protein
CTD PMID:22885370 PMID:27897231 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions
increases expression
ISO platycodin D inhibits the reaction [MK 2206 results in increased expression of ERBB2 protein] CTD PMID:27897231 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO MK 2206 promotes the reaction [Cadmium Chloride results in increased expression of ERN1 protein] CTD PMID:29444456 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO MK 2206 results in increased expression of F3 protein CTD PMID:25569083 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fas Fas cell surface death receptor affects response to substance ISO MK 2206 affects the susceptibility to FAS protein CTD PMID:31445927 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP
ISO
MK 2206 inhibits the reaction [Diethylhexyl Phthalate results in increased expression of FN1 protein]
MK 2206 inhibits the reaction [Radon results in increased expression of FN1 protein]
[MK 2206 co-treated with U 0126] results in decreased expression of FN1 mRNA
CTD PMID:29669060 PMID:30723155 PMID:32949624 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP MK 2206 inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of GSK3B protein] CTD PMID:29669060 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions EXP MK 2206 inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]] CTD PMID:25597859 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO MK 2206 inhibits the reaction [Particulate Matter results in increased expression of IL1B mRNA]; MK 2206 inhibits the reaction [Particulate Matter results in increased secretion of IL1B protein] CTD PMID:31018152 PMID:32687961 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO MK 2206 inhibits the reaction [AGT protein modified form results in increased secretion of IL6 protein]; MK 2206 inhibits the reaction [Particulate Matter results in increased expression of IL6 mRNA] CTD PMID:30354818 PMID:32687961 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Lep leptin multiple interactions ISO MK 2206 inhibits the reaction [8-(4-chlorophenylthio)-2'-O-methyladenosine-3',5'-monophosphate acetoxymethyl ester analog results in increased secretion of LEP protein] CTD PMID:27381457 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lepr leptin receptor multiple interactions ISO LEPR affects the reaction [MK 2206 results in decreased phosphorylation of AKT1 protein] CTD PMID:22949526 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions ISO MK 2206 promotes the reaction [Cadmium Chloride results in increased expression of MAP3K5 protein] CTD PMID:29444456 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
ISO U 0126 promotes the reaction [MK 2206 results in decreased phosphorylation of MAPK1 protein]
[MK 2206 co-treated with PD 0325901] results in decreased phosphorylation of MAPK1 protein
CTD PMID:27634878 PMID:30723155 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation
multiple interactions
ISO MK 2206 results in decreased phosphorylation of MAPK3 protein
[MK 2206 co-treated with PD 0325901] results in decreased phosphorylation of MAPK3 protein
U 0126 promotes the reaction [MK 2206 results in decreased phosphorylation of MAPK3 protein]
CTD PMID:27634878 PMID:30723155 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions ISO [PD 0325901 co-treated with MK 2206] results in increased expression of MCL1 protein; [romidepsin co-treated with MK 2206] results in increased expression of MCL1 protein; [romidepsin co-treated with PD 0325901 co-treated with MK 2206] results in increased expression of MCL1 protein CTD PMID:27634878 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO MTOR gene mutant form promotes the reaction [MK 2206 results in decreased expression of RPS6 protein modified form]
MK 2206 inhibits the reaction [Radon results in increased expression of MTOR protein modified form]
CTD PMID:29384525 PMID:32949624 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [PD 0325901 co-treated with MK 2206] results in increased cleavage of PARP1 protein; [romidepsin co-treated with MK 2206] results in increased cleavage of PARP1 protein; romidepsin promotes the reaction [[PD 0325901 co-treated with MK 2206] results in increased cleavage of PARP1 protein] CTD PMID:27634878 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 multiple interactions ISO MK 2206 inhibits the reaction [PNPLA2 protein results in increased phosphorylation of AKT1 protein] CTD PMID:31476254 NCBI chr 1:196,552,723...196,557,805
Ensembl chr 1:196,552,723...196,557,805
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO MK 2206 inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 protein]; MK 2206 inhibits the reaction [Taurocholic Acid results in increased expression of PTGS2 protein] CTD PMID:26518876 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO MK 2206 inhibits the reaction [Particulate Matter results in increased phosphorylation of RELA protein] CTD PMID:32687961 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation
decreases expression
multiple interactions
ISO MK 2206 results in decreased phosphorylation of RPS6 protein
MK 2206 results in decreased expression of RPS6 protein modified form
MTOR gene mutant form promotes the reaction [MK 2206 results in decreased expression of RPS6 protein modified form]
CTD PMID:22885370 PMID:29384525 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Slc12a3 solute carrier family 12 member 3 multiple interactions ISO MK 2206 inhibits the reaction [INS1 protein results in increased phosphorylation of SLC12A3 protein] CTD PMID:22949526 NCBI chr19:10,630,649...10,679,250
Ensembl chr19:10,631,393...10,669,091
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions
decreases expression
ISO [U 0126 co-treated with MK 2206] results in decreased expression of SNAI1 mRNA
MK 2206 inhibits the reaction [Radon results in increased expression of SNAI1 protein]
MK 2206 results in decreased expression of SNAI1 mRNA
CTD PMID:30723155 PMID:32949624 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snai2 snail family transcriptional repressor 2 multiple interactions ISO [U 0126 co-treated with MK 2206] results in decreased expression of SNAI2 mRNA CTD PMID:30723155 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO MK 2206 binds to and results in increased activity of THRB protein CTD PMID:25752796 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO MK 2206 inhibits the reaction [Particulate Matter results in decreased expression of TJP1 protein] CTD PMID:32687961 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases response to substance
ISO MK 2206 inhibits the reaction [1-nitropyrene results in increased expression of TNF mRNA]; MK 2206 inhibits the reaction [3-nitrofluoranthene results in increased expression of TNF mRNA]; MK 2206 inhibits the reaction [AGT protein modified form results in increased secretion of TNF protein]; MK 2206 inhibits the reaction [Particulate Matter results in increased expression of TNF mRNA]
MK 2206 results in increased susceptibility to TNF protein
CTD PMID:28633978 PMID:30354818 PMID:31445927 PMID:32687961 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [PD 0325901 co-treated with MK 2206] results in increased expression of and results in increased phosphorylation of TRP53 protein CTD PMID:28691888 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Vim vimentin multiple interactions EXP
ISO
MK 2206 inhibits the reaction [Diethylhexyl Phthalate results in increased expression of VIM protein]
MK 2206 inhibits the reaction [Radon results in increased expression of VIM protein]
CTD PMID:29669060 PMID:32949624 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO MK 2206 promotes the reaction [Cadmium Chloride results in increased expression of XBP1 protein alternative form] CTD PMID:29444456 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 multiple interactions
increases expression
ISO [U 0126 co-treated with MK 2206] results in increased expression of ZEB1 mRNA
MK 2206 results in increased expression of ZEB1 mRNA
CTD PMID:30723155 NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 multiple interactions
decreases expression
ISO [U 0126 co-treated with MK 2206] results in decreased expression of ZEB2 mRNA
MK 2206 results in decreased expression of ZEB2 mRNA
CTD PMID:30723155 NCBI chr 3:29,219,765...29,342,094
Ensembl chr 3:29,218,301...29,345,157
JBrowse link
nalidixic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta multiple interactions ISO Nalidixic Acid inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA] CTD PMID:16148020 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions
decreases expression
ISO Nalidixic Acid inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]
Nalidixic Acid results in decreased expression of MMP13 mRNA
CTD PMID:16148020 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
quinalphos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity
multiple interactions
EXP
ISO
quinalphos results in decreased activity of ACHE protein
quinalphos metabolite results in decreased activity of ACHE protein; quinalphos results in decreased activity of ACHE protein
Arsenic promotes the reaction [quinalphos results in decreased activity of ACHE protein]; quinalphos promotes the reaction [Arsenic results in decreased activity of ACHE protein]
CTD PMID:32270456 PMID:33844597 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO quinalphos binds to and results in increased activity of AHR protein CTD PMID:18835618 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Alb albumin multiple interactions EXP [Arsenic co-treated with quinalphos] results in decreased expression of ALB protein CTD PMID:32270456 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Ar androgen receptor multiple interactions ISO Dihydrotestosterone inhibits the reaction [quinalphos results in increased activity of AR protein] CTD PMID:15064155 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Bche butyrylcholinesterase decreases activity
multiple interactions
ISO quinalphos results in decreased activity of BCHE protein
pralidoxime inhibits the reaction [quinalphos results in decreased activity of BCHE protein]
CTD PMID:24052565 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Cat catalase multiple interactions
decreases activity
ISO
EXP
Plant Extracts inhibits the reaction [quinalphos results in decreased activity of CAT protein]
[Arsenic co-treated with quinalphos] results in decreased activity of CAT protein
CTD PMID:24581381 PMID:32270456 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression ISO quinalphos results in increased expression of CYP19A1 mRNA CTD PMID:34014595 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases expression
multiple interactions
ISO quinalphos results in decreased expression of CYP26B1 mRNA
Plant Extracts inhibits the reaction [quinalphos results in decreased expression of CYP26B1 mRNA]
CTD PMID:24581381 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO quinalphos results in increased activity of ESR1 protein CTD PMID:15064155 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 increases activity ISO quinalphos results in increased activity of ESR2 protein CTD PMID:15064155 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
affects activity
EXP [Monocrotophos co-treated with quinalphos] affects the activity of G6PD protein
quinalphos affects the activity of G6PD protein
CTD PMID:24248738 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
affects activity
EXP [Arsenic co-treated with quinalphos] results in decreased activity of GSR protein; [Monocrotophos co-treated with quinalphos] affects the activity of GSR protein
quinalphos results in decreased activity of GSR protein
quinalphos affects the activity of GSR protein
CTD PMID:24248738 PMID:32270456 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 multiple interactions
decreases expression
ISO Plant Extracts inhibits the reaction [quinalphos results in decreased expression of HSD3B3 mRNA] CTD PMID:24581381 NCBI chr 2:186,138,044...186,144,024
Ensembl chr 2:186,138,044...186,144,033
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO quinalphos binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
decreases expression
ISO Plant Extracts inhibits the reaction [quinalphos results in decreased expression of STAR mRNA]; Plant Extracts inhibits the reaction [quinalphos results in decreased expression of STAR protein]
quinalphos results in decreased expression of STAR mRNA; quinalphos results in decreased expression of STAR protein
CTD PMID:24581381 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
quinomethionate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btg2 BTG anti-proliferation factor 2 affects expression ISO quinomethionate affects the expression of BTG2 mRNA CTD PMID:15387888 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta affects expression ISO quinomethionate affects the expression of CEBPD mRNA CTD PMID:15387888 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 affects expression ISO quinomethionate affects the expression of CXCL2 mRNA CTD PMID:15387888 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 affects expression
increases expression
ISO quinomethionate affects the expression of CYP2A13 mRNA
quinomethionate results in increased expression of CYP2A13 mRNA
CTD PMID:15387888 PMID:18214805 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
G Etv4 ETS variant transcription factor 4 affects expression ISO quinomethionate affects the expression of ETV4 mRNA CTD PMID:15387888 NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974
JBrowse link
G Ewsr1 EWS RNA-binding protein 1 affects expression ISO quinomethionate affects the expression of EWSR1 mRNA CTD PMID:15387888 NCBI chr14:79,965,365...79,994,108
Ensembl chr14:79,965,368...79,994,544
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 affects expression ISO quinomethionate affects the expression of FKBP5 mRNA CTD PMID:15387888 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit affects expression ISO quinomethionate affects the expression of FOS mRNA CTD PMID:15387888 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha affects expression ISO quinomethionate affects the expression of GADD45A mRNA CTD PMID:15387888 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Hnrnpf heterogeneous nuclear ribonucleoprotein F affects expression ISO quinomethionate affects the expression of HNRNPF mRNA CTD PMID:15387888 NCBI chr 4:151,083,262...151,104,464
Ensembl chr 4:151,083,062...151,109,038
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit affects expression ISO quinomethionate affects the expression of JUNB mRNA CTD PMID:15387888 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit affects expression ISO quinomethionate affects the expression of JUND mRNA CTD PMID:15387888 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Lmnb1 lamin B1 affects expression ISO quinomethionate affects the expression of LMNB1 mRNA CTD PMID:15387888 NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 affects expression ISO quinomethionate affects the expression of MAP2K1 mRNA CTD PMID:15387888 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Mat2a methionine adenosyltransferase 2A affects expression ISO quinomethionate affects the expression of MAT2A mRNA CTD PMID:15387888 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
JBrowse link
G Nfkbia NFKB inhibitor alpha affects expression ISO quinomethionate affects the expression of NFKBIA mRNA CTD PMID:15387888 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Phb prohibitin affects expression ISO quinomethionate affects the expression of PHB mRNA CTD PMID:15387888 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
JBrowse link
G Ppib peptidylprolyl isomerase B affects expression ISO quinomethionate affects the expression of PPIB mRNA CTD PMID:15387888 NCBI chr 8:66,603,877...66,609,734
Ensembl chr 8:66,603,861...66,630,428
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase affects expression ISO quinomethionate affects the expression of RAF1 mRNA CTD PMID:15387888 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rarg retinoic acid receptor, gamma affects expression ISO quinomethionate affects the expression of RARG mRNA CTD PMID:15387888 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177
JBrowse link
G Rbm39 RNA binding motif protein 39 affects expression ISO quinomethionate affects the expression of RBM39 mRNA CTD PMID:15387888 NCBI chr 3:144,662,998...144,696,222
Ensembl chr 3:144,663,001...144,696,213
JBrowse link
G Rnd3 Rho family GTPase 3 affects expression ISO quinomethionate affects the expression of RND3 mRNA CTD PMID:15387888 NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 affects expression ISO quinomethionate affects the expression of SUMO1 mRNA CTD PMID:15387888 NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761
JBrowse link
G Tgfa transforming growth factor alpha affects expression ISO quinomethionate affects the expression of TGFA mRNA CTD PMID:15387888 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 affects expression ISO quinomethionate affects the expression of UQCRC2 mRNA CTD PMID:15387888 NCBI chr 1:175,167,933...175,198,499
Ensembl chr 1:175,167,894...175,199,453
JBrowse link
G Vegfa vascular endothelial growth factor A affects expression ISO quinomethionate affects the expression of VEGFA mRNA CTD PMID:15387888 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
quizalofop-ethyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox1 acyl-CoA oxidase 1 increases activity
increases expression
multiple interactions
EXP quizalofop-ethyl analog results in increased activity of ACOX1 protein
quizalofop-ethyl analog results in increased expression of ACOX1 mRNA
PPARA protein affects the reaction [quizalofop-ethyl analog results in increased activity of ACOX1 protein]; PPARA protein affects the reaction [quizalofop-ethyl analog results in increased expression of ACOX1 mRNA]
CTD PMID:29626562 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Cat catalase increases activity EXP quizalofop-ethyl analog results in increased activity of CAT protein CTD PMID:29626562 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases response to substance
multiple interactions
EXP PPARA protein results in increased susceptibility to quizalofop-ethyl analog
PPARA protein affects the reaction [quizalofop-ethyl analog results in increased activity of ACOX1 protein]; PPARA protein affects the reaction [quizalofop-ethyl analog results in increased expression of ACOX1 mRNA]
CTD PMID:29626562 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases activity ISO quizalofop-ethyl results in increased activity of PPARG protein CTD PMID:31086981 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
trovafloxacin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha decreases expression EXP trovafloxacin results in decreased expression of ACACA mRNA CTD PMID:24136188 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acsf2 acyl-CoA synthetase family member 2 decreases expression EXP trovafloxacin results in decreased expression of ACSF2 mRNA CTD PMID:24136188 NCBI chr10:79,504,510...79,546,714
Ensembl chr10:79,504,511...79,546,673
JBrowse link
G Actb actin, beta decreases expression EXP trovafloxacin results in decreased expression of ACTB mRNA CTD PMID:24136188 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Actg1 actin, gamma 1 decreases expression EXP trovafloxacin results in decreased expression of ACTG1 mRNA CTD PMID:24136188 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
JBrowse link
G Acy1 aminoacylase 1 decreases expression EXP trovafloxacin results in decreased expression of ACY1 mRNA CTD PMID:24136188 NCBI chr 8:107,072,354...107,077,756
Ensembl chr 8:107,072,358...107,077,682
JBrowse link
G Adap2 ArfGAP with dual PH domains 2 increases expression EXP trovafloxacin results in increased expression of ADAP2 mRNA CTD PMID:24136188 NCBI chr10:65,138,006...65,166,147
Ensembl chr10:65,138,020...65,165,604
JBrowse link
G Adipor2 adiponectin receptor 2 decreases expression EXP trovafloxacin results in decreased expression of ADIPOR2 mRNA CTD PMID:24136188 NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ADRB2 mRNA CTD PMID:18930950 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 decreases expression EXP trovafloxacin results in decreased expression of AKR7A3 mRNA CTD PMID:24136188 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions
ISO trovafloxacin results in increased phosphorylation of AKT1 protein
TNF protein promotes the reaction [trovafloxacin results in increased phosphorylation of AKT1 protein]
CTD PMID:33609687 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression EXP trovafloxacin results in decreased expression of ALDH1A1 mRNA CTD PMID:24136188 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 decreases expression EXP trovafloxacin results in decreased expression of ALDH1B1 mRNA CTD PMID:24136188 NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378
JBrowse link
G Amd1 adenosylmethionine decarboxylase 1 decreases expression EXP trovafloxacin results in decreased expression of AMD1 mRNA CTD PMID:24136188 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476
JBrowse link
G Ammecr1l AMMECR1 like increases expression EXP trovafloxacin results in increased expression of AMMECR1L mRNA CTD PMID:24136188 NCBI chr18:23,386,114...23,411,177
Ensembl chr18:23,386,903...23,410,920
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ANGPTL4 mRNA CTD PMID:18930950 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Ap1s1 adaptor related protein complex 1 subunit sigma 1 decreases expression EXP trovafloxacin results in decreased expression of AP1S1 mRNA CTD PMID:24136188 NCBI chr12:19,625,267...19,635,792
Ensembl chr12:19,625,332...19,756,713
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of APEX1 mRNA CTD PMID:18930950 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Apoa5 apolipoprotein A5 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of APOA5 mRNA CTD PMID:18930950 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link
G Arhgap24 Rho GTPase activating protein 24 decreases expression EXP trovafloxacin results in decreased expression of ARHGAP24 mRNA CTD PMID:24136188 NCBI chr14:6,800,631...7,184,001
Ensembl chr14:6,800,631...7,183,823
JBrowse link
G Arid5b AT-rich interaction domain 5B multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ARID5B mRNA CTD PMID:18930950 NCBI chr20:20,307,731...20,490,746
Ensembl chr20:20,307,731...20,487,433
JBrowse link
G Armt1 acidic residue methyltransferase 1 decreases expression EXP trovafloxacin results in decreased expression of ARMT1 mRNA CTD PMID:24136188 NCBI chr 1:40,894,558...40,918,302
Ensembl chr 1:40,894,550...40,918,302
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions
increases phosphorylation
ISO pyrazolanthrone inhibits the reaction [trovafloxacin results in increased phosphorylation of ATF2 protein] CTD PMID:24525298 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Atg10 autophagy related 10 multiple interactions ISO [trovafloxacin co-treated with TNF protein] results in increased expression of ATG10 mRNA CTD PMID:33609687 NCBI chr 2:22,109,304...22,398,313
Ensembl chr 2:22,108,426...22,398,233
JBrowse link
G Atg101 autophagy related 101 increases expression ISO trovafloxacin results in increased expression of ATG101 mRNA CTD PMID:33609687 NCBI chr 7:132,398,477...132,407,643
Ensembl chr 7:132,398,483...132,407,633
JBrowse link
G Atg12 autophagy related 12 increases expression ISO trovafloxacin results in increased expression of ATG12 mRNA CTD PMID:33609687 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
JBrowse link
G Atg14 autophagy related 14 increases expression
multiple interactions
ISO trovafloxacin results in increased expression of ATG14 mRNA
TNF protein inhibits the reaction [trovafloxacin results in increased expression of ATG14 mRNA]
CTD PMID:33609687 NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113
JBrowse link
G Atg16l1 autophagy related 16-like 1 increases expression
multiple interactions
ISO trovafloxacin results in increased expression of ATG16L1 mRNA
[trovafloxacin co-treated with TNF protein] results in increased expression of ATG16L1 mRNA
CTD PMID:33609687 NCBI chr 9:88,420,737...88,457,530
Ensembl chr 9:88,422,038...88,457,529
JBrowse link
G Atg16l2 autophagy related 16-like 2 decreases expression ISO trovafloxacin results in decreased expression of ATG16L2 mRNA CTD PMID:33609687 NCBI chr 1:155,687,386...155,703,419
Ensembl chr 1:155,684,564...155,703,420
JBrowse link
G Atg2a autophagy related 2A multiple interactions ISO [trovafloxacin co-treated with TNF protein] results in increased expression of ATG2A mRNA CTD PMID:33609687 NCBI chr 1:203,542,559...203,562,242
Ensembl chr 1:203,542,559...203,562,242
JBrowse link
G Atg2b autophagy related 2B increases expression ISO trovafloxacin results in increased expression of ATG2B mRNA CTD PMID:33609687 NCBI chr 6:124,522,283...124,592,412
Ensembl chr 6:124,525,523...124,592,015
JBrowse link
G Atg3 autophagy related 3 increases expression
multiple interactions
ISO trovafloxacin results in increased expression of ATG3 mRNA
[trovafloxacin co-treated with TNF protein] results in increased expression of ATG3 mRNA
CTD PMID:33609687 NCBI chr11:55,624,928...55,653,212
Ensembl chr11:55,624,917...55,653,224
JBrowse link
G Atg4a autophagy related 4A, cysteine peptidase increases expression
multiple interactions
ISO trovafloxacin results in increased expression of ATG4A mRNA
[trovafloxacin co-treated with TNF protein] results in increased expression of ATG4A mRNA
CTD PMID:33609687 NCBI chr  X:104,665,345...104,765,271 JBrowse link
G Atg4c autophagy related 4C, cysteine peptidase multiple interactions ISO [trovafloxacin co-treated with TNF protein] results in decreased expression of ATG4C mRNA CTD PMID:33609687 NCBI chr 5:113,867,218...113,935,534
Ensembl chr 5:113,867,092...113,934,830
JBrowse link
G Atg5 autophagy related 5 affects response to substance
increases expression
multiple interactions
ISO ATG5 protein affects the susceptibility to trovafloxacin
trovafloxacin results in increased expression of ATG5 mRNA
ATG5 protein affects the reaction [trovafloxacin results in increased cleavage of CASP3 protein]; ATG5 protein affects the reaction [trovafloxacin results in increased cleavage of PARP1 protein]; ATG5 protein affects the reaction [trovafloxacin results in increased phosphorylation of MAPK1 protein]; ATG5 protein affects the reaction [trovafloxacin results in increased phosphorylation of MAPK3 protein]; ATG5 protein affects the reaction [trovafloxacin results in increased phosphorylation of MAPK8 protein]; TNF protein inhibits the reaction [trovafloxacin results in increased expression of ATG5 mRNA]
CTD PMID:33609687 NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atg9b autophagy related 9B increases expression
multiple interactions
ISO trovafloxacin results in increased expression of ATG9B mRNA
TNF protein promotes the reaction [trovafloxacin results in increased expression of ATG9B mRNA]; trovafloxacin promotes the reaction [TNF protein results in increased expression of ATG9B mRNA]
CTD PMID:33609687 NCBI chr 4:10,784,934...10,793,832
Ensembl chr 4:10,786,114...10,793,651
JBrowse link
G Atp6v0e2 ATPase, H+ transporting V0 subunit e2 decreases expression EXP trovafloxacin results in decreased expression of ATP6V0E2 mRNA CTD PMID:24136188 NCBI chr 4:77,484,868...77,488,016
Ensembl chr 4:77,482,226...77,488,777
JBrowse link
G Atr ATR serine/threonine kinase multiple interactions ISO 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [[trovafloxacin co-treated with TNF protein] results in increased phosphorylation of ATR protein]; 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [trovafloxacin results in increased phosphorylation of ATR protein]; [trovafloxacin co-treated with TNF protein] results in increased phosphorylation of and results in increased activity of ATR protein; trovafloxacin results in increased phosphorylation of and results in increased activity of ATR protein; U 0126 inhibits the reaction [trovafloxacin results in increased activity of ATR protein] CTD PMID:25748550 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
JBrowse link
G Atrn attractin increases expression EXP trovafloxacin results in increased expression of ATRN mRNA CTD PMID:24136188 NCBI chr 3:118,110,320...118,244,326
Ensembl chr 3:118,110,229...118,244,322
JBrowse link
G B2m beta-2 microglobulin multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of B2M mRNA CTD PMID:18930950 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of BHLHE40 mRNA CTD PMID:18930950 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions
decreases expression
ISO trovafloxacin inhibits the reaction [TNF protein results in increased expression of BIRC2 mRNA]
trovafloxacin results in decreased expression of BIRC2 protein
[trovafloxacin co-treated with TNF protein] results in decreased expression of BIRC2 mRNA
trovafloxacin results in decreased expression of BIRC2 mRNA
CTD PMID:32035082 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions
decreases expression
ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of BIRC3 mRNA
[trovafloxacin co-treated with TNF protein] results in increased expression of BIRC3 mRNA
trovafloxacin results in decreased expression of BIRC3 mRNA
CTD PMID:18930950 PMID:32035082 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Bpnt1 3'(2'), 5'-bisphosphate nucleotidase 1 decreases expression EXP trovafloxacin results in decreased expression of BPNT1 mRNA CTD PMID:24136188 NCBI chr13:96,865,634...96,893,506
Ensembl chr13:96,868,580...96,893,503
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 decreases expression EXP trovafloxacin results in decreased expression of BST2 mRNA CTD PMID:24136188 NCBI chr16:18,217,404...18,220,979
Ensembl chr16:18,217,407...18,220,979
JBrowse link
G Caprin1 cell cycle associated protein 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CAPRIN1 mRNA CTD PMID:18930950 NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502
JBrowse link
G Casd1 CAS1 domain containing 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CASD1 mRNA CTD PMID:18930950 NCBI chr 4:32,658,888...32,739,224
Ensembl chr 4:32,658,748...32,739,202
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
increases activity
ISO [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [trovafloxacin results in increased activity of CASP3 protein]; [TNF protein co-treated with trovafloxacin] results in increased activity of CASP3 protein; [trovafloxacin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [trovafloxacin co-treated with IL1B protein] results in increased activity of CASP3 protein; [trovafloxacin co-treated with IL6 protein] results in increased activity of CASP3 protein; [trovafloxacin co-treated with TNF protein] results in increased activity of CASP3 protein; ATG5 protein affects the reaction [trovafloxacin results in increased cleavage of CASP3 protein]; U 0126 inhibits the reaction [[TNF protein co-treated with trovafloxacin] results in increased activity of CASP3 protein]
[TNF protein co-treated with trovafloxacin] results in increased cleavage of CASP3 protein
CTD PMID:19638433 PMID:24097668 PMID:25748550 PMID:30876886 PMID:33609687 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp6 caspase 6 increases expression EXP trovafloxacin results in increased expression of CASP6 mRNA CTD PMID:24136188 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp7 caspase 7 decreases expression EXP trovafloxacin results in decreased expression of CASP7 mRNA CTD PMID:24136188 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [trovafloxacin co-treated with TNF protein] results in increased activity of CASP8 protein CTD PMID:24097668 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions ISO [trovafloxacin co-treated with TNF protein] results in increased activity of CASP9 protein CTD PMID:24097668 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccdc6 coiled-coil domain containing 6 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CCDC6 mRNA CTD PMID:18930950 NCBI chr20:18,432,177...18,528,186
Ensembl chr20:18,433,695...18,528,658
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO trovafloxacin promotes the reaction [TNF protein results in increased expression of CCL2 protein] CTD PMID:19638433 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccnb2 cyclin B2 decreases expression EXP trovafloxacin results in decreased expression of CCNB2 mRNA CTD PMID:24136188 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP trovafloxacin results in decreased expression of CCND1 mRNA CTD PMID:24136188 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cd36 CD36 molecule decreases expression EXP trovafloxacin results in decreased expression of CD36 mRNA CTD PMID:24136188 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cd8b CD8b molecule multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CD8B mRNA CTD PMID:18930950 NCBI chr 4:103,312,596...103,328,523
Ensembl chr 4:103,312,578...103,328,553
JBrowse link
G Cdc20 cell division cycle 20 decreases expression EXP trovafloxacin results in decreased expression of CDC20 mRNA CTD PMID:24136188 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdc42ep4 CDC42 effector protein 4 increases expression EXP trovafloxacin results in increased expression of CDC42EP4 mRNA CTD PMID:24136188 NCBI chr10:98,772,613...98,797,924
Ensembl chr10:98,772,495...98,797,695
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression EXP trovafloxacin results in decreased expression of CDK1 mRNA CTD PMID:24136188 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk16 cyclin-dependent kinase 16 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CDK16 mRNA CTD PMID:18930950 NCBI chr  X:1,492,814...1,504,309
Ensembl chr  X:1,492,814...1,504,148
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CDKN1A mRNA
trovafloxacin results in increased expression of CDKN1A mRNA
CTD PMID:18930950 PMID:25748550 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression EXP trovafloxacin results in decreased expression of CDKN3 mRNA CTD PMID:24136188 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CEBPA mRNA CTD PMID:18930950 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Chfr checkpoint with forkhead and ring finger domains multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CHFR mRNA CTD PMID:18930950 NCBI chr12:46,504,497...46,538,104
Ensembl chr12:46,504,497...46,538,014
JBrowse link
G Chka choline kinase alpha multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CHKA mRNA CTD PMID:18930950 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression EXP trovafloxacin results in decreased expression of CKS2 mRNA CTD PMID:24136188 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Cldn14 claudin 14 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CLDN14 mRNA CTD PMID:18930950 NCBI chr11:33,232,281...33,329,440
Ensembl chr11:33,232,220...33,329,171
JBrowse link
G Clint1 clathrin interactor 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CLINT1 mRNA CTD PMID:18930950 NCBI chr10:30,298,618...30,353,185
Ensembl chr10:30,298,704...30,353,063
JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of COMT mRNA CTD PMID:18930950 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Copg1 COPI coat complex subunit gamma 1 decreases expression EXP trovafloxacin results in decreased expression of COPG1 mRNA CTD PMID:24136188 NCBI chr 4:120,366,540...120,392,502 JBrowse link
G Cpox coproporphyrinogen oxidase decreases expression EXP trovafloxacin results in decreased expression of CPOX mRNA CTD PMID:24136188 NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP trovafloxacin results in increased expression of CPT1A mRNA CTD PMID:24136188 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Crk CRK proto-oncogene, adaptor protein multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CRK mRNA CTD PMID:18930950 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406
JBrowse link
G Cs citrate synthase decreases expression EXP trovafloxacin results in decreased expression of CS mRNA CTD PMID:24136188 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CXCL2 mRNA; trovafloxacin promotes the reaction [TNF protein results in increased expression of CXCL2 protein] CTD PMID:18930950 PMID:19638433 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CXCL3 mRNA; trovafloxacin promotes the reaction [TNF protein results in increased expression of CXCL1 protein] CTD PMID:18930950 PMID:19638433 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO trovafloxacin results in decreased activity of CYP19A1 protein CTD PMID:26141389 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp2b12 cytochrome P450, family 2, subfamily b, polypeptide 12 decreases expression EXP trovafloxacin results in decreased expression of CYP2B12 mRNA CTD PMID:24136188 NCBI chr 1:82,007,609...82,019,409
Ensembl chr 1:82,007,609...82,080,480
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CYP7A1 mRNA CTD PMID:18930950 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 increases expression EXP trovafloxacin results in increased expression of CYP8B1 mRNA CTD PMID:24136188 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
JBrowse link
G Dapk1 death associated protein kinase 1 decreases expression EXP trovafloxacin results in decreased expression of DAPK1 mRNA CTD PMID:24136188 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases expression ISO trovafloxacin results in decreased expression of DDIT3 mRNA CTD PMID:24136188 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddx1 DEAD-box helicase 1 decreases expression EXP trovafloxacin results in decreased expression of DDX1 mRNA CTD PMID:24136188 NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365
JBrowse link
G Ddx17 DEAD-box helicase 17 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of DDX17 mRNA CTD PMID:18930950 NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193
JBrowse link
G Derl2 derlin 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of DERL2 mRNA CTD PMID:18930950 NCBI chr10:55,727,764...55,739,462
Ensembl chr10:55,727,643...55,739,518
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 decreases expression EXP trovafloxacin results in decreased expression of DGAT2 mRNA CTD PMID:24136188 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase decreases expression EXP trovafloxacin results in decreased expression of DLST mRNA CTD PMID:24136188 NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296
JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of DNAJB2 mRNA CTD PMID:18930950 NCBI chr 9:76,731,060...76,739,278
Ensembl chr 9:76,731,065...76,739,277
JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 decreases expression EXP trovafloxacin results in decreased expression of DNPH1 mRNA CTD PMID:24136188 NCBI chr 9:14,481,296...14,484,034
Ensembl chr 9:14,481,066...14,484,022
JBrowse link
G Dtymk deoxythymidylate kinase decreases expression EXP trovafloxacin results in decreased expression of DTYMK mRNA CTD PMID:24136188 NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870
JBrowse link
G Dusp16 dual specificity phosphatase 16 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of DUSP16 mRNA CTD PMID:18930950 NCBI chr 4:167,546,780...167,629,949
Ensembl chr 4:167,548,155...167,629,980
JBrowse link
G Dusp8 dual specificity phosphatase 8 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of DUSP8 mRNA CTD PMID:18930950 NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921
JBrowse link
G Dut deoxyuridine triphosphatase decreases expression EXP trovafloxacin results in decreased expression of DUT mRNA CTD PMID:24136188 NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of EGFR mRNA CTD PMID:18930950 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha decreases expression EXP trovafloxacin results in decreased expression of EIF2S1 mRNA CTD PMID:24136188 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of EIF2S2 mRNA CTD PMID:18930950 NCBI chr 3:143,374,652...143,395,460
Ensembl chr 3:143,373,686...143,395,432
JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of EIF3A mRNA CTD PMID:18930950 NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C decreases expression EXP trovafloxacin results in decreased expression of EIF3C mRNA CTD PMID:24136188 NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493
JBrowse link
G Eif3l eukaryotic translation initiation factor 3, subunit L decreases expression EXP trovafloxacin results in decreased expression of EIF3L mRNA CTD PMID:24136188 NCBI chr 7:110,652,565...110,663,614
Ensembl chr 7:110,627,107...110,663,614
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 increases expression EXP trovafloxacin results in increased expression of EIF4A2 mRNA CTD PMID:24136188 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO [trovafloxacin co-treated with TNF protein] results in increased phosphorylation of EIF4EBP1 protein; Sirolimus inhibits the reaction [[trovafloxacin co-treated with TNF protein] results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:33609687 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Eif6 eukaryotic translation initiation factor 6 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of EIF6 mRNA CTD PMID:18930950 NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 decreases expression EXP trovafloxacin results in decreased expression of ELOVL6 mRNA CTD PMID:24136188 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
JBrowse link
G Emc1 ER membrane protein complex subunit 1 decreases expression EXP trovafloxacin results in decreased expression of EMC1 mRNA CTD PMID:24136188 NCBI chr 5:151,608,557...151,633,888
Ensembl chr 5:151,608,568...151,633,888
JBrowse link
G Ephx1 epoxide hydrolase 1 decreases expression EXP trovafloxacin results in decreased expression of EPHX1 mRNA CTD PMID:24136188 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Ergic1 endoplasmic reticulum-golgi intermediate compartment 1 decreases expression EXP trovafloxacin results in decreased expression of ERGIC1 mRNA CTD PMID:24136188 NCBI chr10:16,531,192...16,627,183
Ensembl chr10:16,531,194...16,626,957
JBrowse link
G Erp29 endoplasmic reticulum protein 29 decreases expression EXP trovafloxacin results in decreased expression of ERP29 mRNA CTD PMID:24136188 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ERRFI1 mRNA CTD PMID:18930950 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ETS2 mRNA CTD PMID:18930950 NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319
JBrowse link
G F2 coagulation factor II multiple interactions ISO [Lipopolysaccharides co-treated with trovafloxacin] results in increased activity of F2 protein CTD PMID:19367693 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G Fam98a family with sequence similarity 98, member A decreases expression EXP trovafloxacin results in decreased expression of FAM98A mRNA CTD PMID:24136188 NCBI chr 6:19,874,082...19,888,744
Ensembl chr 6:19,874,071...19,888,742
JBrowse link
G Fasn fatty acid synthase multiple interactions
decreases expression
ISO
EXP
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of FASN mRNA
trovafloxacin results in decreased expression of FASN mRNA
CTD PMID:18930950 PMID:24136188 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbxo9 f-box protein 9 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of FBXO9 mRNA CTD PMID:18930950 NCBI chr 8:78,958,482...78,984,015
Ensembl chr 8:78,958,483...78,983,949
JBrowse link
G Fga fibrinogen alpha chain multiple interactions ISO [Lipopolysaccharides co-treated with trovafloxacin] results in increased expression of FGA protein CTD PMID:19367693 NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 decreases expression EXP trovafloxacin results in decreased expression of FKBP4 mRNA CTD PMID:24136188 NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833
JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 increases expression EXP trovafloxacin results in increased expression of FMO3 mRNA CTD PMID:24136188 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of FOS mRNA CTD PMID:18930950 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fzd7 frizzled class receptor 7 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of FZD7 mRNA CTD PMID:18930950 NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of G6PC mRNA CTD PMID:18930950 NCBI chr10:86,307,400...86,318,766 JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases expression EXP trovafloxacin results in decreased expression of G6PD mRNA CTD PMID:24136188 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 multiple interactions
increases expression
ISO [trovafloxacin co-treated with TNF protein] results in increased expression of GABARAPL1 mRNA
trovafloxacin results in increased expression of GABARAPL1 mRNA
CTD PMID:33609687 NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450
JBrowse link
G Gabarapl2 GABA type A receptor associated protein like 2 multiple interactions
increases expression
ISO TNF protein inhibits the reaction [trovafloxacin results in increased expression of GABARAPL2 mRNA] CTD PMID:33609687 NCBI chr19:39,910,572...39,921,408
Ensembl chr19:39,910,534...39,924,628
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma decreases expression EXP trovafloxacin results in decreased expression of GADD45G mRNA CTD PMID:24136188 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase decreases expression EXP trovafloxacin results in decreased expression of GAPDH mRNA CTD PMID:24136188 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gcgr glucagon receptor multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of GCGR mRNA CTD PMID:18930950 NCBI chr10:105,808,474...105,816,641
Ensembl chr10:105,808,473...105,816,640
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression
multiple interactions
EXP
ISO
trovafloxacin results in decreased expression of GCLC mRNA
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of GCLC mRNA
CTD PMID:18930950 PMID:24136188 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gfm1 G elongation factor, mitochondrial 1 decreases expression EXP trovafloxacin results in decreased expression of GFM1 mRNA CTD PMID:24136188 NCBI chr 2:151,700,573...151,745,477
Ensembl chr 2:151,700,564...151,745,471
JBrowse link
G Ggcx gamma-glutamyl carboxylase decreases expression EXP trovafloxacin results in decreased expression of GGCX mRNA CTD PMID:24136188 NCBI chr 4:104,469,737...104,485,631
Ensembl chr 4:104,469,765...104,487,063
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GJA1 mRNA CTD PMID:18930950 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Glrx3 glutaredoxin 3 decreases expression EXP trovafloxacin results in decreased expression of GLRX3 mRNA CTD PMID:24136188 NCBI chr 1:192,241,707...192,272,012
Ensembl chr 1:192,241,701...192,272,010
JBrowse link
G Glyat glycine-N-acyltransferase increases expression EXP trovafloxacin results in increased expression of GLYAT mRNA CTD PMID:24136188 NCBI chr 1:209,704,178...209,724,949
Ensembl chr 1:209,704,268...209,724,942
JBrowse link
G Gnl3 G protein nucleolar 3 increases expression EXP trovafloxacin results in increased expression of GNL3 mRNA CTD PMID:24136188 NCBI chr16:6,207,402...6,213,491
Ensembl chr16:6,207,402...6,213,392
JBrowse link
G Gnpnat1 glucosamine-phosphate N-acetyltransferase 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of GNPNAT1 mRNA CTD PMID:18930950 NCBI chr15:18,596,180...18,608,854
Ensembl chr15:18,596,442...18,608,739
JBrowse link
G Golga2 golgin A2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of GOLGA2 mRNA CTD PMID:18930950 NCBI chr 3:15,583,862...15,604,279
Ensembl chr 3:15,584,039...15,604,279
JBrowse link
G Golga4 golgin A4 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of GOLGA4 mRNA CTD PMID:18930950 NCBI chr 8:118,208,200...118,285,003 JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression EXP trovafloxacin results in decreased expression of GPAM mRNA CTD PMID:24136188 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 increases expression EXP trovafloxacin results in increased expression of GPLD1 mRNA CTD PMID:24136188 NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
JBrowse link
G Gsr glutathione-disulfide reductase decreases expression EXP trovafloxacin results in decreased expression of GSR mRNA CTD PMID:24136188 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gss glutathione synthetase decreases expression EXP trovafloxacin results in decreased expression of GSS mRNA CTD PMID:24136188 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases expression EXP trovafloxacin results in decreased expression of GSTA3 mRNA CTD PMID:24136188 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases phosphorylation
increases expression
ISO [TNF protein co-treated with trovafloxacin] results in increased expression of H2AX protein modified form; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[TNF protein co-treated with trovafloxacin] results in increased expression of H2AX protein modified form]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [trovafloxacin results in increased expression of H2AX protein modified form]; TNF protein promotes the reaction [trovafloxacin results in increased expression of H2AX protein modified form]
trovafloxacin results in increased phosphorylation of H2AX protein
CTD PMID:24817034 PMID:25748550 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 decreases expression EXP trovafloxacin results in decreased expression of HACD3 mRNA CTD PMID:24136188 NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507
JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 increases expression EXP trovafloxacin results in increased expression of HACL1 mRNA CTD PMID:24136188 NCBI chr16:6,826,881...6,863,027
Ensembl chr16:6,824,906...6,863,027
JBrowse link
G Hao2 hydroxyacid oxidase 2 increases expression EXP trovafloxacin results in increased expression of HAO2 mRNA CTD PMID:24136188 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425
JBrowse link
G Hmgn3 high mobility group nucleosomal binding domain 3 decreases expression EXP trovafloxacin results in decreased expression of HMGN3 mRNA CTD PMID:24136188 NCBI chr 8:84,022,493...84,059,329
Ensembl chr 8:84,022,495...84,062,976
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of HMOX1 mRNA CTD PMID:18930950 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnrnpf heterogeneous nuclear ribonucleoprotein F multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of HNRNPF mRNA CTD PMID:18930950 NCBI chr 4:151,083,262...151,104,464
Ensembl chr 4:151,083,062...151,109,038
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 decreases expression EXP trovafloxacin results in decreased expression of HSPH1 mRNA CTD PMID:24136188 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 decreases expression EXP trovafloxacin results in decreased expression of HTATIP2 mRNA CTD PMID:24136188 NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
decreases expression
ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ICAM1 mRNA; trovafloxacin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]
[trovafloxacin co-treated with TNF protein] results in increased expression of ICAM1 mRNA
trovafloxacin results in decreased expression of ICAM1 mRNA
CTD PMID:18930950 PMID:32035082 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id2 inhibitor of DNA binding 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of ID2 mRNA CTD PMID:18930950 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Ide insulin degrading enzyme decreases expression EXP trovafloxacin results in decreased expression of IDE mRNA CTD PMID:24136188 NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 decreases expression EXP trovafloxacin results in decreased expression of IDH2 mRNA CTD PMID:24136188 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Ifng interferon gamma multiple interactions ISO
EXP
IFNG protein promotes the reaction [[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF protein]; IFNG protein results in increased susceptibility to [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5]; trovafloxacin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IFNG protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of IFNG protein]
[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to trovafloxacin
CTD PMID:18930950 PMID:19362101 PMID:19638433 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression
multiple interactions
EXP
ISO
trovafloxacin results in increased expression of IFRD1 mRNA
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IFRD1 mRNA
CTD PMID:18930950 PMID:24136188 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IGFBP1 mRNA CTD PMID:18930950 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Il17ra interleukin 17 receptor A multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL17RA mRNA CTD PMID:18930950 NCBI chr 4:153,667,534...153,690,174
Ensembl chr 4:153,667,534...153,690,174
JBrowse link
G Il18 interleukin 18 multiple interactions ISO IL18 protein results in increased susceptibility to [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5]; trovafloxacin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL18 protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of IL18 protein] CTD PMID:18930950 PMID:19638433 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO
EXP
[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to trovafloxacin; [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to trovafloxacin CTD PMID:19362101 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [trovafloxacin results in increased activity of CASP3 protein]; [trovafloxacin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [trovafloxacin co-treated with IL1B protein] affects the localization of SELE protein; [trovafloxacin co-treated with IL1B protein] results in increased activity of CASP3 protein; [trovafloxacin co-treated with IL1B protein] results in increased expression of SELE mRNA; trovafloxacin promotes the reaction [IL1B protein results in increased secretion of SELE protein]
trovafloxacin promotes the reaction [TNF protein results in increased expression of IL1B protein]
CTD PMID:10822086 PMID:19638433 PMID:30876886 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to trovafloxacin; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [trovafloxacin results in increased activity of CASP3 protein]; [trovafloxacin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [trovafloxacin co-treated with IL6 protein] results in increased activity of CASP3 protein
trovafloxacin promotes the reaction [TNF protein results in increased expression of IL6 protein]
CTD PMID:19362101 PMID:19638433 PMID:30876886 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 increases expression EXP trovafloxacin results in increased expression of IP6K2 mRNA CTD PMID:24136188 NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166
JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions
decreases expression
ISO
EXP
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IRF1 mRNA
trovafloxacin results in decreased expression of IRF1 mRNA
CTD PMID:18930950 PMID:24136188 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ISG20 mRNA CTD PMID:18930950 NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027
JBrowse link
G Ist1 IST1 factor associated with ESCRT-III increases expression EXP trovafloxacin results in increased expression of IST1 mRNA CTD PMID:24136188 NCBI chr19:37,648,840...37,671,019
Ensembl chr19:37,648,095...37,670,956
JBrowse link
G Ivns1abp influenza virus NS1A binding protein multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IVNS1ABP mRNA CTD PMID:18930950 NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of JUNB mRNA CTD PMID:18930950 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Klf9 Kruppel-like factor 9 increases expression EXP trovafloxacin results in increased expression of KLF9 mRNA CTD PMID:24136188 NCBI chr 1:220,700,108...220,725,029
Ensembl chr 1:220,700,108...220,725,037
JBrowse link
G Klhl24 kelch-like family member 24 increases expression EXP trovafloxacin results in increased expression of KLHL24 mRNA CTD PMID:24136188 NCBI chr11:80,843,621...80,877,693
Ensembl chr11:80,846,755...80,877,636
JBrowse link
G Kpna2 karyopherin subunit alpha 2 decreases expression EXP trovafloxacin results in decreased expression of KPNA2 mRNA CTD PMID:24136188 NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150
JBrowse link
G Kpnb1 karyopherin subunit beta 1 decreases expression EXP trovafloxacin results in decreased expression of KPNB1 mRNA CTD PMID:24136188 NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
JBrowse link
G Krt18 keratin 18 decreases expression EXP trovafloxacin results in decreased expression of KRT18 mRNA CTD PMID:24136188 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
JBrowse link
G Laptm4b lysosomal protein transmembrane 4 beta decreases expression EXP trovafloxacin results in decreased expression of LAPTM4B mRNA CTD PMID:24136188 NCBI chr 7:65,434,525...65,477,386
Ensembl chr 7:65,434,394...65,477,383
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of LDLR mRNA CTD PMID:18930950 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Letm1 leucine zipper and EF-hand containing transmembrane protein 1 decreases expression EXP trovafloxacin results in decreased expression of LETM1 mRNA CTD PMID:24136188 NCBI chr14:76,942,647...76,982,220
Ensembl chr14:76,942,729...76,984,904
JBrowse link
G Lgalsl galectin-like decreases expression EXP trovafloxacin results in decreased expression of LGALSL mRNA CTD PMID:24136188 NCBI chr14:94,996,991...95,004,499
Ensembl chr14:94,996,990...95,004,980
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of LITAF mRNA CTD PMID:18930950 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763
JBrowse link
G Lmna lamin A/C decreases expression EXP trovafloxacin results in decreased expression of LMNA mRNA CTD PMID:24136188 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G Lpin1 lipin 1 increases expression EXP trovafloxacin results in increased expression of LPIN1 mRNA CTD PMID:24136188 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Lrp6 LDL receptor related protein 6 increases expression EXP trovafloxacin results in increased expression of LRP6 mRNA CTD PMID:24136188 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Lsm4 LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression EXP trovafloxacin results in decreased expression of LSM4 mRNA CTD PMID:24136188 NCBI chr16:18,755,481...18,761,106
Ensembl chr16:18,755,484...18,760,926
JBrowse link
G Lta4h leukotriene A4 hydrolase decreases expression EXP trovafloxacin results in decreased expression of LTA4H mRNA CTD PMID:24136188 NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600
JBrowse link
G Lyz2 lysozyme 2 decreases expression EXP trovafloxacin results in decreased expression of LYZ2 mRNA CTD PMID:24136188 NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106
JBrowse link
G Mal2 mal, T-cell differentiation protein 2 decreases expression EXP trovafloxacin results in decreased expression of MAL2 mRNA CTD PMID:24136188 NCBI chr 7:85,900,453...85,933,433
Ensembl chr 7:85,900,453...85,933,429
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of MANF mRNA CTD PMID:18930950 NCBI chr 8:107,500,856...107,551,595
Ensembl chr 8:107,548,352...107,551,438
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha multiple interactions
increases expression
ISO TNF protein inhibits the reaction [trovafloxacin results in increased expression of MAP1LC3A mRNA] CTD PMID:33609687 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases expression
ISO [trovafloxacin co-treated with TNF protein] results in increased expression of MAP1LC3B mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [trovafloxacin results in increased expression of and results in increased lipidation of MAP1LC3B protein]; TNF protein inhibits the reaction [trovafloxacin results in increased expression of and results in increased lipidation of MAP1LC3B protein]; trovafloxacin results in increased expression of and results in increased lipidation of MAP1LC3B protein
trovafloxacin results in increased expression of MAP1LC3B mRNA
CTD PMID:33609687 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of MAP2K7 mRNA CTD PMID:18930950 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MAP3K8 mRNA CTD PMID:18930950 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases activity
increases phosphorylation
multiple interactions
ISO trovafloxacin results in increased activity of MAPK1 protein
trovafloxacin results in increased phosphorylation of MAPK1 protein
[trovafloxacin co-treated with TNF protein] results in increased phosphorylation of MAPK1 protein; ATG5 protein affects the reaction [trovafloxacin results in increased phosphorylation of MAPK1 protein]
U 0126 inhibits the reaction [trovafloxacin results in increased activity of MAPK1 protein]
CTD PMID:24525298 PMID:32035082 PMID:33609687 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases activity
increases phosphorylation
multiple interactions
ISO trovafloxacin results in increased activity of MAPK3 protein
trovafloxacin results in increased phosphorylation of MAPK3 protein
[trovafloxacin co-treated with TNF protein] results in increased phosphorylation of MAPK3 protein; ATG5 protein affects the reaction [trovafloxacin results in increased phosphorylation of MAPK3 protein]
U 0126 inhibits the reaction [trovafloxacin results in increased activity of MAPK3 protein]
CTD PMID:24525298 PMID:32035082 PMID:33609687 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions
ISO trovafloxacin results in increased phosphorylation of MAPK8 protein
ATG5 protein affects the reaction [trovafloxacin results in increased phosphorylation of MAPK8 protein]
CTD PMID:33609687 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 multiple interactions
increases phosphorylation
ISO SB 203580 inhibits the reaction [trovafloxacin results in increased phosphorylation of MAPKAPK2 protein] CTD PMID:24525298 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457
JBrowse link
G Mavs mitochondrial antiviral signaling protein multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of MAVS mRNA CTD PMID:18930950 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094
JBrowse link
G Mdh2 malate dehydrogenase 2 decreases expression EXP trovafloxacin results in decreased expression of MDH2 mRNA CTD PMID:24136188 NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271
JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MDM2 mRNA CTD PMID:18930950 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Me1 malic enzyme 1 decreases expression EXP trovafloxacin results in decreased expression of ME1 mRNA CTD PMID:24136188 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Med20 mediator complex subunit 20 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of MED20 mRNA CTD PMID:18930950 NCBI chr 9:13,370,146...13,382,756
Ensembl chr 9:13,370,146...13,382,476
JBrowse link
G Memo1 mediator of cell motility 1 decreases expression EXP trovafloxacin results in decreased expression of MEMO1 mRNA CTD PMID:24136188 NCBI chr 6:21,144,525...21,234,363
Ensembl chr 6:21,125,639...21,234,561
JBrowse link
G Mgll monoglyceride lipase decreases expression EXP trovafloxacin results in decreased expression of MGLL mRNA CTD PMID:24136188 NCBI chr 4:121,192,187...121,294,187
Ensembl chr 4:121,192,195...121,294,179
JBrowse link
G Mir877 microRNA 877 increases expression ISO trovafloxacin results in increased expression of MIR877 mRNA CTD PMID:27713024 NCBI chr20:2,811,476...2,811,560
Ensembl chr20:2,811,476...2,811,560
JBrowse link
G Mlxipl MLX interacting protein-like multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of MLXIPL mRNA CTD PMID:18930950 NCBI chr12:21,542,964...21,577,120
Ensembl chr12:21,543,576...21,577,112
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MMP13 mRNA CTD PMID:18930950 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Mogs mannosyl-oligosaccharide glucosidase multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of MOGS mRNA CTD PMID:18930950 NCBI chr 4:115,621,623...115,625,026
Ensembl chr 4:115,621,623...115,625,032
JBrowse link
G Mphosph8 M-phase phosphoprotein 8 increases expression EXP trovafloxacin results in increased expression of MPHOSPH8 mRNA CTD PMID:24136188 NCBI chr15:30,800,546...30,828,415 JBrowse link
G Mrpl12 mitochondrial ribosomal protein L12 decreases expression EXP trovafloxacin results in decreased expression of MRPL12 mRNA CTD PMID:24136188 NCBI chr10:105,758,410...105,762,913
Ensembl chr10:105,758,410...105,762,913
JBrowse link
G Mrps18b mitochondrial ribosomal protein S18B decreases expression EXP trovafloxacin results in decreased expression of MRPS18B mRNA CTD PMID:24136188 NCBI chr20:2,838,174...2,844,260
Ensembl chr20:2,838,030...2,844,260
JBrowse link
G Mt1 metallothionein 1 increases expression EXP trovafloxacin results in increased expression of MT1A mRNA CTD PMID:24136188 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Mt2A metallothionein 2A multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MT1E mRNA CTD PMID:18930950 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mttp microsomal triglyceride transfer protein decreases expression EXP trovafloxacin results in decreased expression of MTTP mRNA CTD PMID:24136188 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MYD88 mRNA CTD PMID:18930950 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Naa15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit decreases expression EXP trovafloxacin results in decreased expression of NAA15 mRNA CTD PMID:24136188 NCBI chr 2:135,458,018...135,520,756
Ensembl chr 2:135,457,948...135,520,756
JBrowse link
G Ndufaf4 NADH:ubiquinone oxidoreductase complex assembly factor 4 decreases expression EXP trovafloxacin results in decreased expression of NDUFAF4 mRNA CTD PMID:24136188 NCBI chr 5:38,605,169...38,610,341
Ensembl chr 5:38,605,153...38,610,336
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NEDD4L mRNA CTD PMID:18930950 NCBI chr18:58,393,759...58,726,709
Ensembl chr18:58,393,509...58,723,137
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NEDD9 mRNA CTD PMID:18930950 NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases expression
ISO [Lipopolysaccharides co-treated with trovafloxacin] results in increased expression of NFKBIA mRNA; [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NFKBIA mRNA; [trovafloxacin co-treated with TNF protein] results in decreased expression of NFKBIA protein; trovafloxacin promotes the reaction [TNF protein results in increased expression of NFKBIA mRNA]
[trovafloxacin co-treated with TNF protein] results in increased expression of NFKBIA mRNA
trovafloxacin results in increased expression of NFKBIA mRNA; trovafloxacin results in increased expression of NFKBIA protein
CTD PMID:18930950 PMID:32035082 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbiz NFKB inhibitor zeta multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NFKBIZ mRNA CTD PMID:18930950 NCBI chr11:44,782,676...44,810,723
Ensembl chr11:44,782,676...44,810,723
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 decreases expression EXP trovafloxacin results in decreased expression of NME1 mRNA CTD PMID:24136188 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 decreases expression EXP trovafloxacin results in decreased expression of NME2 mRNA CTD PMID:24136188 NCBI chr10:78,898,097...78,903,600
Ensembl chr10:78,897,770...78,903,538
JBrowse link
G Noct nocturnin multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NOCT mRNA CTD PMID:18930950 NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400
JBrowse link
G Notch2 notch receptor 2 decreases expression EXP trovafloxacin results in decreased expression of NOTCH2 mRNA CTD PMID:24136188 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088
JBrowse link
G Nr2f6 nuclear receptor subfamily 2, group F, member 6 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of NR2F6 mRNA CTD PMID:18930950 NCBI chr16:18,046,012...18,053,914
Ensembl chr16:18,046,013...18,053,459
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases expression EXP trovafloxacin results in increased expression of NR3C1 mRNA CTD PMID:24136188 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nudt7 nudix hydrolase 7 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of NUDT7 mRNA CTD PMID:18930950 NCBI chr19:42,125,679...42,151,198
Ensembl chr19:42,125,711...42,151,081
JBrowse link
G Nup98 nucleoporin 98 and 96 precursor increases expression EXP trovafloxacin results in increased expression of NUP98 mRNA CTD PMID:24136188 NCBI chr 1:156,494,423...156,591,415
Ensembl chr 1:156,494,423...156,591,415
JBrowse link
G Obp3 alpha-2u globulin PGCL4 increases expression EXP trovafloxacin results in increased expression of OBP3 mRNA CTD PMID:24136188 NCBI chr 5:74,842,316...74,845,858
Ensembl chr 5:74,842,316...74,845,757
JBrowse link
G P2ry2 purinergic receptor P2Y2 decreases expression EXP trovafloxacin results in decreased expression of P2RY2 mRNA CTD PMID:24136188 NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632
JBrowse link
G Pacsin2 protein kinase C and casein kinase substrate in neurons 2 decreases expression EXP trovafloxacin results in decreased expression of PACSIN2 mRNA CTD PMID:24136188 NCBI chr 7:114,505,525...114,599,087
Ensembl chr 7:114,505,152...114,598,546
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO trovafloxacin results in increased cleavage of PARP1 protein
ATG5 protein affects the reaction [trovafloxacin results in increased cleavage of PARP1 protein]
CTD PMID:33609687 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 increases expression EXP trovafloxacin results in increased expression of PBLD1 mRNA CTD PMID:24136188 NCBI chr20:25,551,274...25,566,543
Ensembl chr20:25,551,275...25,565,614
JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 decreases expression EXP trovafloxacin results in decreased expression of PCSK6 mRNA CTD PMID:24136188 NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:119,429,265...119,627,596
JBrowse link
G Pctp phosphatidylcholine transfer protein decreases expression EXP trovafloxacin results in decreased expression of PCTP mRNA CTD PMID:24136188 NCBI chr10:74,808,887...74,856,260
Ensembl chr10:74,808,887...74,849,867
JBrowse link
G Pde4b phosphodiesterase 4B decreases expression
multiple interactions
EXP
ISO
trovafloxacin results in decreased expression of PDE4B mRNA
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PDE4B mRNA
CTD PMID:18930950 PMID:24136188 NCBI chr 5:116,799,827...117,367,707
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pdhx pyruvate dehydrogenase complex, component X decreases expression EXP trovafloxacin results in decreased expression of PDHX mRNA CTD PMID:24136188 NCBI chr 3:89,372,472...89,396,759
Ensembl chr 3:89,371,497...89,431,773
JBrowse link
G Pdlim1 PDZ and LIM domain 1 decreases expression EXP trovafloxacin results in decreased expression of PDLIM1 mRNA CTD PMID:24136188 NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076
JBrowse link
G Perp p53 apoptosis effector related to PMP22 decreases expression EXP trovafloxacin results in decreased expression of PERP mRNA CTD PMID:24136188 NCBI chr 1:13,542,067...13,554,514
Ensembl chr 1:13,542,067...13,554,511
JBrowse link
G Pex2 peroxisomal biogenesis factor 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of PEX2 mRNA CTD PMID:18930950 NCBI chr 2:96,050,380...96,072,928
Ensembl chr 2:96,045,958...96,073,404
JBrowse link
G Pgk1 phosphoglycerate kinase 1 decreases expression EXP trovafloxacin results in decreased expression of PGK1 mRNA CTD PMID:24136188 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Pgm1 phosphoglucomutase 1 decreases expression EXP trovafloxacin results in decreased expression of PGM1 mRNA CTD PMID:24136188 NCBI chr 5:114,595,298...114,654,728
Ensembl chr 5:114,595,293...114,654,728
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PHLDA1 mRNA CTD PMID:18930950 NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861
JBrowse link
G Pink1 PTEN induced kinase 1 increases expression EXP trovafloxacin results in increased expression of PINK1 mRNA CTD PMID:24136188 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PIP5K1A mRNA CTD PMID:18930950 NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598
JBrowse link
G Pisd phosphatidylserine decarboxylase multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of PISD mRNA CTD PMID:18930950 NCBI chr14:77,941,927...77,991,021
Ensembl chr14:77,941,948...77,991,003
JBrowse link
G Plbd1 phospholipase B domain containing 1 decreases expression EXP trovafloxacin results in decreased expression of PLBD1 mRNA CTD PMID:24136188 NCBI chr 4:169,472,983...169,529,277
Ensembl chr 4:169,472,983...169,529,277
JBrowse link
G Plin2 perilipin 2 decreases expression EXP trovafloxacin results in decreased expression of PLIN2 mRNA CTD PMID:24136188 NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Plin3 perilipin 3 decreases expression EXP trovafloxacin results in decreased expression of PLIN3 mRNA CTD PMID:24136188 NCBI chr 9:1,111,178...1,123,117 JBrowse link
G Plk3 polo-like kinase 3 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PLK3 mRNA CTD PMID:18930950 NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317
JBrowse link
G Plpp3 phospholipid phosphatase 3 increases expression EXP trovafloxacin results in increased expression of PLPP3 mRNA CTD PMID:24136188 NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205
JBrowse link
G Pnp purine nucleoside phosphorylase multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PNP2 mRNA CTD PMID:18930950 NCBI chr15:24,170,456...24,178,274
Ensembl chr15:24,170,602...24,203,986
JBrowse link
G Polrmt RNA polymerase mitochondrial multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of POLRMT mRNA CTD PMID:18930950 NCBI chr 7:9,959,532...9,969,791
Ensembl chr 7:9,959,576...9,969,791
JBrowse link
G Ppa1 inorganic pyrophosphatase 1 decreases expression EXP trovafloxacin results in decreased expression of PPA1 mRNA CTD PMID:24136188 NCBI chr20:29,590,733...29,617,711
Ensembl chr20:29,590,707...29,619,215
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO trovafloxacin results in decreased expression of PPARA mRNA CTD PMID:25689681 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppox protoporphyrinogen oxidase decreases expression EXP trovafloxacin results in decreased expression of PPOX mRNA CTD PMID:24136188 NCBI chr13:83,697,661...83,701,998
Ensembl chr13:83,664,891...83,701,805
JBrowse link
G Ppp1r14a protein phosphatase 1, regulatory (inhibitor) subunit 14A decreases expression EXP trovafloxacin results in decreased expression of PPP1R14A mRNA CTD PMID:24136188 NCBI chr 1:84,583,127...84,590,743
Ensembl chr 1:84,586,627...84,590,671
JBrowse link
G Ppp1r14b protein phosphatase 1, regulatory (inhibitor) subunit 14B decreases expression EXP trovafloxacin results in decreased expression of PPP1R14B mRNA CTD PMID:24136188 NCBI chr 1:204,165,210...204,167,320
Ensembl chr 1:204,163,299...204,167,319
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PPP1R15A mRNA CTD PMID:18930950 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Preb prolactin regulatory element binding multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of PREB mRNA CTD PMID:18930950 NCBI chr 6:25,418,805...25,422,594
Ensembl chr 6:25,418,776...25,422,590
JBrowse link
G Proser2 proline and serine rich 2 increases expression EXP trovafloxacin results in increased expression of PROSER2 mRNA CTD PMID:24136188 NCBI chr17:72,151,961...72,187,524
Ensembl chr17:72,151,872...72,185,825
JBrowse link
G Prss23 serine protease 23 decreases expression EXP trovafloxacin results in decreased expression of PRSS23 mRNA CTD PMID:24136188 NCBI chr 1:143,402,725...143,422,182
Ensembl chr 1:143,401,396...143,422,091
JBrowse link
G Psma5 proteasome 20S subunit alpha 5 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PSMA5 mRNA CTD PMID:18930950 NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731
JBrowse link
G Psmb10 proteasome 20S subunit beta 10 decreases expression EXP trovafloxacin results in decreased expression of PSMB10 mRNA CTD PMID:24136188 NCBI chr19:33,830,958...33,833,442 JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of PTEN mRNA CTD PMID:18930950 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptgr2 prostaglandin reductase 2 decreases expression EXP trovafloxacin results in decreased expression of PTGR2 mRNA CTD PMID:24136188 NCBI chr 6:103,931,367...103,963,113
Ensembl chr 6:103,931,409...103,963,111
JBrowse link
G Ptma prothymosin alpha decreases expression EXP trovafloxacin results in decreased expression of PTMA mRNA CTD PMID:24136188 NCBI chr 9:87,176,251...87,180,333
Ensembl chr 9:87,176,230...87,180,333
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 increases expression
multiple interactions
EXP
ISO
trovafloxacin results in increased expression of PTP4A1 mRNA
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PTP4A1 mRNA
CTD PMID:18930950 PMID:24136188 NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PTPN2 mRNA CTD PMID:18930950 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627
JBrowse link
G Ptpn21 protein tyrosine phosphatase, non-receptor type 21 decreases expression EXP trovafloxacin results in decreased expression of PTPN21 mRNA CTD PMID:24136188 NCBI chr 6:117,933,066...117,998,095
Ensembl chr 6:117,933,066...117,998,095
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin decreases expression EXP trovafloxacin results in decreased expression of PTTG1 mRNA CTD PMID:24136188 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
JBrowse link
G Ran RAN, member RAS oncogene family decreases expression EXP trovafloxacin results in decreased expression of RAN mRNA CTD PMID:24136188 NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276
JBrowse link
G Rangap1 RAN GTPase activating protein 1 decreases expression EXP trovafloxacin results in decreased expression of RANGAP1 mRNA CTD PMID:24136188 NCBI chr 7:113,224,695...113,250,441
Ensembl chr 7:113,224,703...113,250,438
JBrowse link
G Rarb retinoic acid receptor, beta decreases expression EXP trovafloxacin results in decreased expression of RARB mRNA CTD PMID:24136188 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression EXP trovafloxacin results in decreased expression of RB1 mRNA CTD PMID:24136188 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 multiple interactions
increases expression
ISO TNF protein inhibits the reaction [trovafloxacin results in increased expression of RB1CC1 mRNA] CTD PMID:33609687 NCBI chr 5:13,161,648...13,225,560
Ensembl chr 5:13,161,648...13,225,560
JBrowse link
G Rcan1 regulator of calcineurin 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of RCAN1 mRNA CTD PMID:18930950 NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045
JBrowse link
G Rdx radixin multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of RDX mRNA CTD PMID:18930950 NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678
JBrowse link
G Reep6 receptor accessory protein 6 decreases expression EXP trovafloxacin results in decreased expression of REEP6 mRNA CTD PMID:24136188 NCBI chr 7:9,373,927...9,380,845
Ensembl chr 7:9,373,927...9,380,597
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of REL mRNA CTD PMID:18930950 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
affects localization
ISO trovafloxacin affects the reaction [TNF protein affects the localization of RELA protein modified form]; trovafloxacin affects the reaction [TNF protein results in increased phosphorylation of RELA protein]
trovafloxacin affects the localization of RELA protein
trovafloxacin affects the reaction [Lipopolysaccharides affects the localization of RELA protein]
CTD PMID:32035082 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G RGD1308742 similar to Complement C5 precursor increases expression EXP trovafloxacin results in increased expression of RGD1308742 mRNA CTD PMID:24136188 NCBI chr 3:18,401,716...18,420,064
Ensembl chr 3:18,404,899...18,420,054
JBrowse link
G RGD1309534 similar to RIKEN cDNA 4931406C07 decreases expression EXP trovafloxacin results in decreased expression of RGD1309534 mRNA CTD PMID:24136188 NCBI chr 8:12,123,839...12,146,412
Ensembl chr 8:12,123,823...12,146,473
JBrowse link
G RGD1564804 similar to chromosome 1 open reading frame 50 increases expression EXP trovafloxacin results in increased expression of RGD1564804 mRNA CTD PMID:24136188 NCBI chr 5:132,837,135...132,841,744
Ensembl chr 5:132,836,506...132,841,762
JBrowse link
G Rmdn2 regulator of microtubule dynamics 2 decreases expression EXP trovafloxacin results in decreased expression of RMDN2 mRNA CTD PMID:24136188 NCBI chr 6:15,372,569...15,443,000
Ensembl chr 6:15,375,496...15,441,480
JBrowse link
G Rnd3 Rho family GTPase 3 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of RND3 mRNA CTD PMID:18930950 NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327
JBrowse link
G Rnf26 ring finger protein 26 decreases expression EXP trovafloxacin results in decreased expression of RNF26 mRNA CTD PMID:24136188 NCBI chr 8:44,454,551...44,456,745
Ensembl chr 8:44,454,292...44,457,331
JBrowse link
G Rnf39 ring finger protein 39 increases expression EXP trovafloxacin results in increased expression of RNF39 mRNA CTD PMID:24136188 NCBI chr20:1,604,794...1,610,283
Ensembl chr20:1,604,794...1,610,283
JBrowse link
G Rnf6 ring finger protein 6 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of RNF6 mRNA CTD PMID:18930950 NCBI chr12:8,816,777...8,826,870
Ensembl chr12:8,816,833...8,826,847
JBrowse link
G Rpa1 replication protein A1 decreases expression EXP trovafloxacin results in decreased expression of RPA1 mRNA CTD PMID:24136188 NCBI chr10:60,148,869...60,199,999
Ensembl chr10:60,148,793...60,199,949
JBrowse link
G Rpl7l1 ribosomal protein L7-like 1 decreases expression EXP trovafloxacin results in decreased expression of RPL7L1 mRNA CTD PMID:24136188 NCBI chr 9:14,198,101...14,206,119
Ensembl chr 9:14,198,092...14,206,110
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions ISO [trovafloxacin co-treated with TNF protein] results in increased phosphorylation of RPS6KB1 protein CTD PMID:33609687 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 decreases expression EXP trovafloxacin results in decreased expression of RRM2 mRNA CTD PMID:24136188 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G Rsrp1 arginine and serine rich protein 1 increases expression EXP trovafloxacin results in increased expression of RSRP1 mRNA CTD PMID:24136188 NCBI chr 5:147,147,774...147,151,523
Ensembl chr 5:147,147,784...147,151,523
JBrowse link
G S100a11 S100 calcium binding protein A11 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of S100A11 mRNA CTD PMID:18930950 NCBI chr 2:179,191,504...179,197,098
Ensembl chr 2:179,191,715...179,197,044
JBrowse link
G Sae1 SUMO1 activating enzyme subunit 1 decreases expression EXP trovafloxacin results in decreased expression of SAE1 mRNA CTD PMID:24136188 NCBI chr 1:77,030,961...77,086,937
Ensembl chr 1:77,030,965...77,086,986
JBrowse link
G Sarnp SAP domain containing ribonucleoprotein decreases expression EXP trovafloxacin results in decreased expression of SARNP mRNA CTD PMID:24136188 NCBI chr 7:1,251,096...1,305,335
Ensembl chr 7:1,251,098...1,305,332
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression EXP trovafloxacin results in increased expression of SAT1 mRNA CTD PMID:24136188 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP trovafloxacin results in decreased expression of SCD1 mRNA CTD PMID:24136188 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Sds serine dehydratase increases expression EXP trovafloxacin results in increased expression of SDS mRNA CTD PMID:24136188 NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
JBrowse link
G Sec24d SEC24 homolog D, COPII coat complex component decreases expression EXP trovafloxacin results in decreased expression of SEC24D mRNA CTD PMID:24136188 NCBI chr 2:211,418,557...211,526,588
Ensembl chr 2:211,418,623...211,526,587
JBrowse link
G Sele selectin E multiple interactions ISO [trovafloxacin co-treated with IL1B protein] affects the localization of SELE protein; [trovafloxacin co-treated with IL1B protein] results in increased expression of SELE mRNA; trovafloxacin promotes the reaction [IL1B protein results in increased secretion of SELE protein]
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SELE mRNA
CTD PMID:10822086 PMID:18930950 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Senp2 SUMO specific peptidase 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of SENP2 mRNA CTD PMID:18930950 NCBI chr11:78,981,429...79,018,274
Ensembl chr11:78,981,432...79,018,238
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SERPINE1 mRNA; SERPINE1 protein results in increased susceptibility to [trovafloxacin co-treated with Lipopolysaccharides]; trovafloxacin promotes the reaction [Lipopolysaccharides results in increased expression of SERPINE1 protein] CTD PMID:18930950 PMID:19367693 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sf3a3 splicing factor 3a, subunit 3 decreases expression EXP trovafloxacin results in decreased expression of SF3A3 mRNA CTD PMID:24136188 NCBI chr 5:136,967,713...136,987,345
Ensembl chr 5:136,967,691...136,987,361
JBrowse link
G Sfpq splicing factor proline and glutamine rich decreases expression EXP trovafloxacin results in decreased expression of SFPQ mRNA CTD PMID:24136188 NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472
JBrowse link
G Sh3bp5 SH3-domain binding protein 5 increases expression EXP trovafloxacin results in increased expression of SH3BP5 mRNA CTD PMID:24136188 NCBI chr16:6,583,462...6,678,344
Ensembl chr16:6,583,465...6,698,975
JBrowse link
G Skil SKI-like proto-oncogene multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SKIL mRNA CTD PMID:18930950 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080
JBrowse link
G Slc11a2 solute carrier family 11 member 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SLC11A2 mRNA CTD PMID:18930950 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
JBrowse link
G Slc17a2 solute carrier family 17, member 2 increases expression EXP trovafloxacin results in increased expression of SLC17A2 mRNA CTD PMID:24136188 NCBI chr17:41,318,312...41,339,012
Ensembl chr17:41,319,701...41,336,325
JBrowse link
G Slc17a3 solute carrier family 17 member 3 decreases expression
multiple interactions
EXP
ISO
trovafloxacin results in decreased expression of SLC17A3 mRNA
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of SLC17A3 mRNA
CTD PMID:18930950 PMID:24136188 NCBI chr17:41,270,804...41,300,132
Ensembl chr17:41,270,812...41,295,256
JBrowse link
G Slc22a1 solute carrier family 22 member 1 decreases expression EXP trovafloxacin results in decreased expression of SLC22A1 mRNA CTD PMID:24136188 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc34a2 solute carrier family 34 member 2 decreases expression EXP trovafloxacin results in decreased expression of SLC34A2 mRNA CTD PMID:24136188 NCBI chr14:57,910,931...57,930,236
Ensembl chr14:57,910,480...57,930,436
JBrowse link
G Slc35e3 solute carrier family 35, member E3 decreases expression EXP trovafloxacin results in decreased expression of SLC35E3 mRNA CTD PMID:24136188 NCBI chr 7:53,337,091...53,350,152
Ensembl chr 7:53,337,095...53,350,165
JBrowse link
G Slc39a14 solute carrier family 39 member 14 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SLC39A14 mRNA CTD PMID:18930950 NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524
JBrowse link
G Slc41a2 solute carrier family 41 member 2 decreases expression EXP trovafloxacin results in decreased expression of SLC41A2 mRNA CTD PMID:24136188 NCBI chr 7:20,383,714...20,491,178
Ensembl chr 7:20,383,757...20,491,166
JBrowse link
G Slc46a1 solute carrier family 46 member 1 increases expression EXP trovafloxacin results in increased expression of SLC46A1 mRNA CTD PMID:24136188 NCBI chr10:63,361,504...63,367,940
Ensembl chr10:63,361,486...63,368,848
JBrowse link
G Slc7a2 solute carrier family 7 member 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SLC7A2 mRNA CTD PMID:18930950 NCBI chr16:51,417,478...51,470,784
Ensembl chr16:51,417,493...51,470,784
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SLC9A3R1 mRNA CTD PMID:18930950 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 increases expression EXP trovafloxacin results in increased expression of SLCO1A2 mRNA CTD PMID:24136188 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of SLCO1B3 mRNA CTD PMID:18930950 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981
JBrowse link
G Smarcd2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of SMARCD2 mRNA CTD PMID:18930950 NCBI chr10:91,193,752...91,202,817
Ensembl chr10:91,193,752...91,204,341
JBrowse link
G Smndc1 survival motor neuron domain containing 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SMNDC1 mRNA CTD PMID:18930950 NCBI chr 1:252,389,675...252,400,749
Ensembl chr 1:252,389,673...252,401,616
JBrowse link
G Snd1 staphylococcal nuclease and tudor domain containing 1 decreases expression EXP trovafloxacin results in decreased expression of SND1 mRNA CTD PMID:24136188 NCBI chr 4:57,095,205...57,494,501
Ensembl chr 4:57,095,208...57,530,843
JBrowse link
G Snx4 sorting nexin 4 multiple interactions ISO [trovafloxacin co-treated with TNF protein] results in decreased expression of SNX4 mRNA CTD PMID:33609687 NCBI chr11:67,460,872...67,518,143
Ensembl chr11:67,460,870...67,518,174
JBrowse link
G Socs2 suppressor of cytokine signaling 2 increases expression
multiple interactions
EXP
ISO
trovafloxacin results in increased expression of SOCS2 mRNA
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SOCS2 mRNA
CTD PMID:18930950 PMID:24136188 NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SOCS3 mRNA CTD PMID:18930950 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SOD2 mRNA CTD PMID:18930950 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Spart spartin decreases expression EXP trovafloxacin results in decreased expression of SPG20 mRNA CTD PMID:24136188 NCBI chr 2:139,292,630...139,319,248
Ensembl chr 2:139,292,355...139,319,248
JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SPRED2 mRNA CTD PMID:18930950 NCBI chr14:94,226,312...94,248,162
Ensembl chr14:94,148,837...94,249,162
JBrowse link
G Sptssa serine palmitoyltransferase, small subunit A increases expression EXP trovafloxacin results in increased expression of SPTSSA mRNA CTD PMID:24136188 NCBI chr 6:72,144,714...72,156,130
Ensembl chr 6:72,144,714...72,156,214
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression EXP trovafloxacin results in decreased expression of SREBF1 mRNA CTD PMID:24136188 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srm spermidine synthase decreases expression EXP trovafloxacin results in decreased expression of SRM mRNA CTD PMID:24136188 NCBI chr 5:159,025,919...159,029,076
Ensembl chr 5:159,025,873...159,029,405
JBrowse link
G Srp72 signal recognition particle 72 decreases expression EXP trovafloxacin results in decreased expression of SRP72 mRNA CTD PMID:24136188 NCBI chr14:31,168,175...31,195,717 JBrowse link
G Srrm2 serine/arginine repetitive matrix 2 increases expression EXP trovafloxacin results in increased expression of SRRM2 mRNA CTD PMID:24136188 NCBI chr10:12,815,471...12,848,750
Ensembl chr10:12,815,471...12,848,751
JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of SRSF1 mRNA CTD PMID:18930950 NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336
JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 decreases expression
multiple interactions
EXP
ISO
trovafloxacin results in decreased expression of SRSF2 mRNA
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SRSF2 mRNA
CTD PMID:18930950 PMID:24136188 NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338
JBrowse link
G Srsf3 serine and arginine rich splicing factor 3 decreases expression EXP trovafloxacin results in decreased expression of SRSF3 mRNA CTD PMID:24136188 NCBI chr20:7,091,928...7,101,860
Ensembl chr20:7,091,910...7,101,078
JBrowse link
G Srsf4 serine and arginine rich splicing factor 4 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SRSF4 mRNA CTD PMID:18930950 NCBI chr 5:144,060,981...144,090,798
Ensembl chr 5:144,061,463...144,089,229
JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of SRSF5 mRNA CTD PMID:18930950 NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177
JBrowse link
G Ssx2ip SSX family member 2 interacting protein decreases expression EXP trovafloxacin results in decreased expression of SSX2IP mRNA CTD PMID:24136188 NCBI chr 2:235,298,012...235,330,750
Ensembl chr 2:235,298,088...235,330,745
JBrowse link
G Stag2 stromal antigen 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of STAG2 mRNA CTD PMID:18930950 NCBI chr  X:120,974,687...121,105,677
Ensembl chr  X:120,974,857...121,105,677
JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 increases expression EXP trovafloxacin results in increased expression of STARD4 mRNA CTD PMID:24136188 NCBI chr18:24,814,683...24,830,024
Ensembl chr18:24,817,107...24,830,024
JBrowse link
G Stard5 StAR-related lipid transfer domain containing 5 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of STARD5 mRNA CTD PMID:18930950 NCBI chr 1:137,606,151...137,616,017
Ensembl chr 1:137,606,177...137,616,469
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of STAT3 mRNA CTD PMID:18930950 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stbd1 starch binding domain 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of STBD1 mRNA CTD PMID:18930950 NCBI chr14:15,470,452...15,473,857
Ensembl chr14:15,469,582...15,477,443
JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression EXP trovafloxacin results in decreased expression of STIP1 mRNA CTD PMID:24136188 NCBI chr 1:204,209,434...204,228,452
Ensembl chr 1:204,178,932...204,228,476
JBrowse link
G Stmn1 stathmin 1 decreases expression EXP trovafloxacin results in decreased expression of STMN1 mRNA CTD PMID:24136188 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Sts steroid sulfatase increases expression EXP trovafloxacin results in increased expression of STS mRNA CTD PMID:24136188 NCBI chr  X:42,225,131...42,233,403
Ensembl chr  X:42,225,372...42,233,402
JBrowse link
G Sumo2 small ubiquitin-like modifier 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of SUMO2 mRNA CTD PMID:18930950 NCBI chr10:100,771,941...100,784,503 JBrowse link
G Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SYNCRIP mRNA CTD PMID:18930950 NCBI chr 8:89,402,487...89,435,517
Ensembl chr 8:89,402,866...89,435,515
JBrowse link
G Synrg synergin, gamma increases expression EXP trovafloxacin results in increased expression of SYNRG mRNA CTD PMID:24136188 NCBI chr10:68,848,828...68,931,252 JBrowse link
G Tat tyrosine aminotransferase multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TAT mRNA CTD PMID:18930950 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
JBrowse link
G Tbc1d14 TBC1 domain family, member 14 increases expression EXP trovafloxacin results in increased expression of TBC1D14 mRNA CTD PMID:24136188 NCBI chr14:74,172,652...74,272,182
Ensembl chr14:74,172,664...74,272,183
JBrowse link
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 decreases expression EXP trovafloxacin results in decreased expression of TCIRG1 mRNA CTD PMID:24136188 NCBI chr 1:201,127,034...201,138,787
Ensembl chr 1:201,127,034...201,138,742
JBrowse link
G Tent2 terminal nucleotidyltransferase 2 decreases expression EXP trovafloxacin results in decreased expression of TENT2 mRNA CTD PMID:24136188 NCBI chr 2:24,380,135...24,432,099
Ensembl chr 2:24,380,225...24,432,099
JBrowse link
G Tfdp1 transcription factor Dp-1 decreases expression EXP trovafloxacin results in decreased expression of TFDP1 mRNA CTD PMID:24136188 NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817
JBrowse link
G Tfg trafficking from ER to golgi regulator multiple interactions
decreases expression
ISO
EXP
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of TFG mRNA
trovafloxacin results in decreased expression of TFG mRNA
CTD PMID:18930950 PMID:24136188 NCBI chr11:43,885,542...43,911,976
Ensembl chr11:43,885,661...43,911,976
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TGIF1 mRNA CTD PMID:18930950 NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802
JBrowse link
G Tgm2 transglutaminase 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TGM2 mRNA CTD PMID:18930950 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
JBrowse link
G Thbs1 thrombospondin 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of THBS1 mRNA CTD PMID:18930950 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Thrap3 thyroid hormone receptor associated protein 3 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of THRAP3 mRNA CTD PMID:18930950 NCBI chr 5:138,445,284...138,487,544
Ensembl chr 5:138,445,295...138,487,477
JBrowse link
G Thrsp thyroid hormone responsive decreases expression EXP trovafloxacin results in decreased expression of THRSP mRNA CTD PMID:24136188 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
JBrowse link
G Tkfc triokinase and FMN cyclase decreases expression EXP trovafloxacin results in decreased expression of TKFC mRNA CTD PMID:24136188 NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737
JBrowse link
G Tkt transketolase decreases expression EXP trovafloxacin results in decreased expression of TKT mRNA CTD PMID:24136188 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
JBrowse link
G Tle1 TLE family member 1, transcriptional corepressor increases expression EXP trovafloxacin results in increased expression of TLE1 mRNA CTD PMID:24136188 NCBI chr 5:85,851,827...85,934,806
Ensembl chr 5:85,851,827...85,934,774
JBrowse link
G Tmem106b transmembrane protein 106B increases expression EXP trovafloxacin results in increased expression of TMEM106B mRNA CTD PMID:24136188 NCBI chr 4:41,328,125...41,347,315
Ensembl chr 4:41,327,994...41,345,619
JBrowse link
G Tmem41a transmembrane protein 41a decreases expression EXP trovafloxacin results in decreased expression of TMEM41A mRNA CTD PMID:24136188 NCBI chr11:79,084,005...79,090,613
Ensembl chr11:79,084,001...79,090,613
JBrowse link
G Tmpo thymopoietin decreases expression EXP trovafloxacin results in decreased expression of TMPO mRNA CTD PMID:24136188 NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727
JBrowse link
G Tmx2 thioredoxin-related transmembrane protein 2 decreases expression EXP trovafloxacin results in decreased expression of TMX2 mRNA CTD PMID:24136188 NCBI chr 3:69,754,937...69,762,587
Ensembl chr 3:69,754,939...69,762,587
JBrowse link
G Tmx4 thioredoxin-related transmembrane protein 4 increases expression EXP trovafloxacin results in increased expression of TMX4 mRNA CTD PMID:24136188 NCBI chr 3:121,856,237...121,899,680
Ensembl chr 3:121,856,261...121,899,641
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases uptake
decreases expression
increases expression
increases response to substance
increases secretion
ISO
EXP
4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [[trovafloxacin co-treated with TNF protein] results in increased phosphorylation of ATR protein]; [IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to trovafloxacin; [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to trovafloxacin; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [trovafloxacin results in increased activity of CASP3 protein]; [TNF protein co-treated with trovafloxacin] results in increased activity of CASP3 protein; [TNF protein co-treated with trovafloxacin] results in increased expression of H2AX protein modified form; [trovafloxacin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [trovafloxacin co-treated with TNF protein] results in decreased expression of ATG4C mRNA; [trovafloxacin co-treated with TNF protein] results in decreased expression of BIRC2 mRNA; [trovafloxacin co-treated with TNF protein] results in decreased expression of SNX4 mRNA; [trovafloxacin co-treated with TNF protein] results in decreased expression of XIAP mRNA; [trovafloxacin co-treated with TNF protein] results in increased activity of CASP3 protein; [trovafloxacin co-treated with TNF protein] results in increased activity of CASP8 protein; [trovafloxacin co-treated with TNF protein] results in increased activity of CASP9 protein; [trovafloxacin co-treated with TNF protein] results in increased expression of ATG10 mRNA; [trovafloxacin co-treated with TNF protein] results in increased expression of ATG16L1 mRNA; [trovafloxacin co-treated with TNF protein] results in increased expression of ATG2A mRNA; [trovafloxacin co-treated with TNF protein] results in increased expression of ATG3 mRNA; [trovafloxacin co-treated with TNF protein] results in increased expression of ATG4A mRNA; [trovafloxacin co-treated with TNF protein] results in increased expression of BIRC3 mRNA; [trovafloxacin co-treated with TNF protein] results in increased expression of GABARAPL1 mRNA; [trovafloxacin co-treated with TNF protein] results in increased expression of ICAM1 mRNA; [trovafloxacin co-treated with TNF protein] results in increased expression of MAP1LC3B mRNA; [trovafloxacin co-treated with TNF protein] results in increased expression of NFKBIA mRNA; [trovafloxacin co-treated with TNF protein] results in increased expression of TNFAIP3 mRNA; [trovafloxacin co-treated with TNF protein] results in increased expression of TNFAIP3 protein; [trovafloxacin co-treated with TNF protein] results in increased expression of ULK2 mRNA; [trovafloxacin co-treated with TNF protein] results in increased phosphorylation of and results in increased activity of ATR protein; [trovafloxacin co-treated with TNF protein] results in increased phosphorylation of EIF4EBP1 protein; [trovafloxacin co-treated with TNF protein] results in increased phosphorylation of MAPK1 protein; [trovafloxacin co-treated with TNF protein] results in increased phosphorylation of MAPK3 protein; [trovafloxacin co-treated with TNF protein] results in increased phosphorylation of RPS6KB1 protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[TNF protein co-treated with trovafloxacin] results in increased expression of H2AX protein modified form]; Sirolimus inhibits the reaction [[trovafloxacin co-treated with TNF protein] results in increased phosphorylation of EIF4EBP1 protein]; TNF protein inhibits the reaction [trovafloxacin results in increased expression of and results in increased lipidation of MAP1LC3B protein]; TNF protein inhibits the reaction [trovafloxacin results in increased expression of ATG14 mRNA]; TNF protein inhibits the reaction [trovafloxacin results in increased expression of ATG5 mRNA]; TNF protein inhibits the reaction [trovafloxacin results in increased expression of GABARAPL2 mRNA]; TNF protein inhibits the reaction [trovafloxacin results in increased expression of MAP1LC3A mRNA]; TNF protein inhibits the reaction [trovafloxacin results in increased expression of MAP1LC3B2 mRNA]; TNF protein inhibits the reaction [trovafloxacin results in increased expression of MAP1LC3C mRNA]; TNF protein inhibits the reaction [trovafloxacin results in increased expression of RB1CC1 mRNA]; TNF protein promotes the reaction [trovafloxacin results in increased expression of ATG9B mRNA]; TNF protein promotes the reaction [trovafloxacin results in increased expression of H2AX protein modified form]; TNF protein promotes the reaction [trovafloxacin results in increased phosphorylation of AKT1 protein]; trovafloxacin affects the reaction [TNF protein affects the localization of RELA protein modified form]; trovafloxacin affects the reaction [TNF protein results in increased phosphorylation of RELA protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of ATG9B mRNA]; U 0126 inhibits the reaction [[TNF protein co-treated with trovafloxacin] results in increased activity of CASP3 protein]
trovafloxacin results in decreased uptake of TNF protein
trovafloxacin results in decreased expression of TNF
trovafloxacin results in increased expression of TNF mRNA; trovafloxacin results in increased expression of TNF protein
trovafloxacin results in increased susceptibility to TNF protein
trovafloxacin results in increased secretion of TNF protein
4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [trovafloxacin promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [trovafloxacin results in increased expression of and results in increased stability of TNF mRNA]; 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [trovafloxacin results in increased expression of TNF protein]; [Lipopolysaccharides co-treated with trovafloxacin] results in increased expression of TNF mRNA; [Pentoxifylline results in decreased expression of TNF mRNA] results in decreased susceptibility to [lipopolysaccharide, E coli O55-B5 co-treated with trovafloxacin]; [TNF protein co-treated with trovafloxacin] results in increased cleavage of CASP3 protein; [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF protein; [trovafloxacin co-treated with TNF protein] results in decreased expression of NFKBIA protein; IFNG protein promotes the reaction [[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF protein]; pyrazolanthrone inhibits the reaction [trovafloxacin promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; pyrazolanthrone inhibits the reaction [trovafloxacin results in increased expression of TNF mRNA]; TNF protein affects the susceptibility to [lipopolysaccharide, E coli O55-B5 co-treated with trovafloxacin]; TNF protein results in increased susceptibility to [Lipopolysaccharides co-treated with trovafloxacin]; trovafloxacin inhibits the reaction [TNF protein results in increased expression of BIRC2 mRNA]; trovafloxacin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; trovafloxacin promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]; trovafloxacin promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of CCL2 protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of CXCL1 protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of CXCL2 protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of IFNG protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of IL18 protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of IL1B protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of IL6 protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of NFKBIA mRNA]; trovafloxacin promotes the reaction [TNF protein results in increased expression of TNFAIP3 mRNA]; trovafloxacin results in increased expression of and results in increased stability of TNF mRNA; U 0126 inhibits the reaction [trovafloxacin promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; U 0126 inhibits the reaction [trovafloxacin results in increased expression of TNF mRNA]
TNF protein results in increased susceptibility to trovafloxacin
CTD PMID:17709330 PMID:18930950 PMID:19362101 PMID:19638433 PMID:24097668 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 multiple interactions
increases expression
ISO [Lipopolysaccharides co-treated with trovafloxacin] results in increased expression of TNFAIP3 mRNA; [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNFAIP3 mRNA; trovafloxacin promotes the reaction [TNF protein results in increased expression of TNFAIP3 mRNA]
[trovafloxacin co-treated with TNF protein] results in increased expression of TNFAIP3 mRNA; [trovafloxacin co-treated with TNF protein] results in increased expression of TNFAIP3 protein
trovafloxacin results in increased expression of TNFAIP3 mRNA
trovafloxacin results in increased expression of TNFAIP3 mRNA; trovafloxacin results in increased expression of TNFAIP3 protein
CTD PMID:18930950 PMID:32035082 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tob2 transducer of ERBB2, 2 increases expression EXP trovafloxacin results in increased expression of TOB2 mRNA CTD PMID:24136188 NCBI chr 7:113,362,703...113,371,423
Ensembl chr 7:113,361,148...113,372,688
JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 decreases expression EXP trovafloxacin results in decreased expression of TOMM70A mRNA CTD PMID:24136188 NCBI chr11:43,378,719...43,417,166
Ensembl chr11:43,377,216...43,417,202
JBrowse link
G Top2a DNA topoisomerase II alpha decreases activity ISO trovafloxacin results in decreased activity of TOP2A protein CTD PMID:24817034 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Tpi1 triosephosphate isomerase 1 decreases expression EXP trovafloxacin results in decreased expression of TPI1 mRNA CTD PMID:24136188 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
G Tpm3 tropomyosin 3 decreases expression EXP trovafloxacin results in decreased expression of TPM3 mRNA CTD PMID:24136188 NCBI chr 2:175,517,198...175,545,014
Ensembl chr 2:175,517,226...175,545,013
JBrowse link
G Tpst1 tyrosylprotein sulfotransferase 1 increases expression EXP trovafloxacin results in increased expression of TPST1 mRNA CTD PMID:24136188 NCBI chr12:26,544,536...26,605,706
Ensembl chr12:26,544,536...26,605,704
JBrowse link
G Trak1 trafficking kinesin protein 1 increases expression EXP trovafloxacin results in increased expression of TRAK1 mRNA CTD PMID:24136188 NCBI chr 8:120,984,445...121,139,357
Ensembl chr 8:120,984,431...121,139,367
JBrowse link
G Ttc7a tetratricopeptide repeat domain 7A decreases expression EXP trovafloxacin results in decreased expression of TTC7A mRNA CTD PMID:24136188 NCBI chr 6:7,159,285...7,261,826
Ensembl chr 6:7,159,061...7,261,892
JBrowse link
G Tuba1c tubulin, alpha 1C decreases expression EXP trovafloxacin results in decreased expression of TUBA1C mRNA CTD PMID:24136188 NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr  X:130,192,016...130,199,647
JBrowse link
G Tuba4a tubulin, alpha 4A decreases expression EXP trovafloxacin results in decreased expression of TUBA4A mRNA CTD PMID:24136188 NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918
JBrowse link
G Tubb2a tubulin, beta 2A class IIa decreases expression EXP trovafloxacin results in decreased expression of TUBB2A mRNA CTD PMID:24136188 NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
JBrowse link
G Tubb4b tubulin, beta 4B class IVb multiple interactions
decreases expression
ISO
EXP
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of TUBB4B mRNA
trovafloxacin results in decreased expression of TUBB4B mRNA
CTD PMID:18930950 PMID:24136188 NCBI chr 3:8,037,844...8,040,294
Ensembl chr 3:8,037,799...8,040,296
JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression EXP trovafloxacin results in decreased expression of TUBB5 mRNA CTD PMID:24136188 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Txlng taxilin gamma multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of TXLNG mRNA CTD PMID:18930950 NCBI chr  X:31,864,066...31,912,931
Ensembl chr  X:31,864,111...31,912,926
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C decreases expression EXP trovafloxacin results in decreased expression of UBE2C mRNA CTD PMID:24136188 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of UBE2I mRNA CTD PMID:18930950 NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443
Ensembl chr10:69,701,618...69,702,443
JBrowse link
G Ubqln1 ubiquilin 1 decreases expression EXP trovafloxacin results in decreased expression of UBQLN1 mRNA CTD PMID:24136188 NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 decreases expression EXP trovafloxacin results in decreased expression of UGT2B17 mRNA CTD PMID:24136188 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 increases expression EXP trovafloxacin results in increased expression of ULK1 mRNA CTD PMID:24136188 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966
JBrowse link
G Ulk2 unc-51 like autophagy activating kinase 2 increases expression
multiple interactions
ISO trovafloxacin results in increased expression of ULK2 mRNA
[trovafloxacin co-treated with TNF protein] results in increased expression of ULK2 mRNA
CTD PMID:33609687 NCBI chr10:46,451,578...46,530,462
Ensembl chr10:46,454,030...46,530,407
JBrowse link
G Umps uridine monophosphate synthetase decreases expression EXP trovafloxacin results in decreased expression of UMPS mRNA CTD PMID:24136188 NCBI chr11:66,806,107...66,816,520
Ensembl chr11:66,806,045...66,821,903
JBrowse link
G Upp1 uridine phosphorylase 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of UPP1 mRNA CTD PMID:18930950 NCBI chr14:83,809,495...83,829,299
Ensembl chr14:83,809,960...83,829,462
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of VEGFA mRNA CTD PMID:18930950 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Wbp1l WW domain binding protein 1-like increases expression EXP trovafloxacin results in increased expression of WBP1L mRNA CTD PMID:24136188 NCBI chr 1:245,472,292...245,528,627
Ensembl chr 1:245,472,296...245,528,627
JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 decreases expression ISO trovafloxacin results in decreased expression of WIPI1 mRNA CTD PMID:33609687 NCBI chr10:94,542,946...94,580,174
Ensembl chr10:94,542,946...94,579,846
JBrowse link
G Xbp1 X-box binding protein 1 increases expression EXP trovafloxacin results in increased expression of XBP1 mRNA CTD PMID:24136188 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of XDH mRNA CTD PMID:18930950 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
G Xiap X-linked inhibitor of apoptosis multiple interactions
decreases expression
ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of XIAP mRNA
[trovafloxacin co-treated with TNF protein] results in decreased expression of XIAP mRNA
trovafloxacin results in decreased expression of XIAP mRNA
CTD PMID:18930950 PMID:32035082 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
G Xpnpep2 X-prolyl aminopeptidase 2 decreases expression EXP trovafloxacin results in decreased expression of XPNPEP2 mRNA CTD PMID:24136188 NCBI chr  X:127,287,765...127,317,036
Ensembl chr  X:127,287,979...127,317,223
JBrowse link
G Xpo1 exportin 1 decreases expression EXP trovafloxacin results in decreased expression of XPO1 mRNA CTD PMID:24136188 NCBI chr14:97,233,263...97,275,536
Ensembl chr14:97,233,270...97,275,498
JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 decreases expression EXP trovafloxacin results in decreased expression of YARS1 mRNA CTD PMID:24136188 NCBI chr 5:141,535,815...141,564,029
Ensembl chr 5:141,535,759...141,563,833
JBrowse link
G Ypel3 yippee-like 3 increases expression EXP trovafloxacin results in increased expression of YPEL3 mRNA CTD PMID:24136188 NCBI chr 1:181,384,385...181,387,706
Ensembl chr 1:181,384,357...181,387,705
JBrowse link
G Ypel5 yippee-like 5 increases expression EXP trovafloxacin results in increased expression of YPEL5 mRNA CTD PMID:24136188 NCBI chr 6:22,656,284...22,671,741
Ensembl chr 6:22,656,285...22,671,691
JBrowse link
G Zfand5 zinc finger AN1-type containing 5 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ZFAND5 mRNA CTD PMID:18930950 NCBI chr 1:218,765,735...218,776,118
Ensembl chr 1:218,766,614...218,775,843
JBrowse link
XL147 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of A2M mRNA CTD PMID:27935865 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
JBrowse link
G Abca8 ATP binding cassette subfamily A member 8 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ABCA8B mRNA CTD PMID:27935865 NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988
JBrowse link
G Abhd14b abhydrolase domain containing 14b multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of ABHD14B mRNA] CTD PMID:29891994 NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119
JBrowse link
G Acod1 aconitate decarboxylase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of ACOD1 mRNA CTD PMID:27935865 NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of ACTA2 mRNA] CTD PMID:29891994 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actg2 actin gamma 2, smooth muscle multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ACTG2 mRNA CTD PMID:27935865 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of ADAM8 mRNA CTD PMID:27935865 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
JBrowse link
G Adcy5 adenylate cyclase 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ADCY5 mRNA CTD PMID:27935865 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974
JBrowse link
G Adcyap1r1 ADCYAP receptor type I multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ADCYAP1R1 mRNA CTD PMID:27935865 NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:84,593,892...84,642,700
JBrowse link
G Adgra2 adhesion G protein-coupled receptor A2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ADGRA2 mRNA CTD PMID:27935865 NCBI chr16:64,932,964...64,971,433
Ensembl chr16:64,933,315...64,971,483
JBrowse link
G Adgrg3 adhesion G protein-coupled receptor G3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of ADGRG3 mRNA CTD PMID:27935865 NCBI chr19:9,972,425...10,001,118
Ensembl chr19:9,972,430...10,001,123
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ADIPOQ mRNA CTD PMID:27935865 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adora1 adenosine A1 receptor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ADORA1 mRNA CTD PMID:27935865 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
JBrowse link
G Agbl1 AGBL carboxypeptidase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of AGBL1 mRNA CTD PMID:27935865 NCBI chr 1:130,043,914...130,950,739
Ensembl chr 1:130,043,970...130,951,638
JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of AGTR2 mRNA CTD PMID:27935865 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of AKR1D1 mRNA CTD PMID:27935865 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372
JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of AMBP mRNA CTD PMID:27935865 NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331
JBrowse link
G Anos1 anosmin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of WFDC17 mRNA CTD PMID:27935865 NCBI chr10:68,561,954...68,562,801
Ensembl chr10:68,561,954...68,562,801
JBrowse link
G Aoc3 amine oxidase, copper containing 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of AOC3 mRNA CTD PMID:27935865 NCBI chr10:86,272,757...86,280,702 JBrowse link
G Apoc2 apolipoprotein C2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of APOC2 mRNA CTD PMID:27935865 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476
JBrowse link
G Apol9a apolipoprotein L 9a multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of APOL6 mRNA CTD PMID:27935865 NCBI chr 7:109,140,871...109,149,799
Ensembl chr 7:109,140,871...109,147,649
JBrowse link
G Arhgap36 Rho GTPase activating protein 36 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ARHGAP36 mRNA CTD PMID:27935865 NCBI chr  X:128,780,148...128,787,169
Ensembl chr  X:128,751,900...128,787,161
JBrowse link
G Arhgef19 Rho guanine nucleotide exchange factor 19 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of ARHGEF19 mRNA] CTD PMID:29891994 NCBI chr 5:153,536,038...153,554,203
Ensembl chr 5:153,536,013...153,554,203
JBrowse link
G Armcx6 armadillo repeat containing, X-linked 6 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of ARMCX6 mRNA] CTD PMID:29891994 NCBI chr  X:97,929,032...97,932,032
Ensembl chr  X:97,929,041...97,931,977
JBrowse link
G Asb10 ankyrin repeat and SOCS box-containing 10 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ASB10 mRNA CTD PMID:27935865 NCBI chr 4:10,630,318...10,644,270
Ensembl chr 4:10,630,448...10,639,060
JBrowse link
G Asb13 ankyrin repeat and SOCS box-containing 13 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of ASB13 mRNA] CTD PMID:29891994 NCBI chr17:66,564,653...66,583,365
Ensembl chr17:66,562,434...66,583,337
JBrowse link
G Asb16 ankyrin repeat and SOCS box-containing 16 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ASB16 mRNA CTD PMID:27935865 NCBI chr10:87,225,976...87,233,078
Ensembl chr10:87,225,912...87,233,078
JBrowse link
G Ascl2 achaete-scute family bHLH transcription factor 2 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of ASCL2 mRNA] CTD PMID:29891994 NCBI chr 1:198,148,999...198,151,406
Ensembl chr 1:198,148,999...198,151,406
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ATP1A2 mRNA CTD PMID:27935865 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of ATP1A3 mRNA CTD PMID:27935865 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
JBrowse link
G Avpr1a arginine vasopressin receptor 1A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of AVPR1A mRNA CTD PMID:27935865 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215
JBrowse link
G B4galnt2 beta-1,4-N-acetyl-galactosaminyl transferase 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of B4GALNT2 mRNA CTD PMID:27935865 NCBI chr10:80,801,594...80,828,005 JBrowse link
G Bend4 BEN domain containing 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of BEND4 mRNA CTD PMID:27935865 NCBI chr14:40,753,048...40,788,686
Ensembl chr14:40,753,077...40,783,504
JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of BHLHA15 mRNA CTD PMID:27935865 NCBI chr12:10,420,465...10,424,641
Ensembl chr12:10,420,467...10,424,713
JBrowse link
G Bpifa5 BPI fold containing family A, member 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of BPIFA5 mRNA CTD PMID:27935865 NCBI chr 3:142,646,103...142,652,884
Ensembl chr 3:142,646,103...142,652,883
JBrowse link
G Bpifb1 BPI fold containing family B, member 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of BPIFB1 mRNA CTD PMID:27935865 NCBI chr 3:142,672,995...142,706,258
Ensembl chr 3:142,672,995...142,706,256
JBrowse link
G Bricd5 BRICHOS domain containing 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of BRICD5 mRNA CTD PMID:27935865 NCBI chr10:13,498,726...13,500,259
Ensembl chr10:13,498,381...13,500,259
JBrowse link
G Btn1a1 butyrophilin, subfamily 1, member A1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of BTN1A1 mRNA CTD PMID:27935865 NCBI chr17:41,654,237...41,663,427
Ensembl chr17:41,654,249...41,664,272
JBrowse link
G C1qtnf2 C1q and TNF related 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of C1QTNF2 mRNA CTD PMID:27935865 NCBI chr10:27,941,948...27,958,926
Ensembl chr10:27,941,948...27,959,185
JBrowse link
G C1qtnf7 C1q and TNF related 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of C1QTNF7 mRNA CTD PMID:27935865 NCBI chr14:67,467,888...67,580,477
Ensembl chr14:67,468,014...67,580,410
JBrowse link
G C5ar1 complement C5a receptor 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of C5AR1 mRNA CTD PMID:27935865 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G C5ar2 complement C5a receptor 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of C5AR2 mRNA CTD PMID:27935865 NCBI chr 1:76,930,381...76,945,432
Ensembl chr 1:76,930,383...76,959,517
JBrowse link
G Ca3 carbonic anhydrase 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CAR3 mRNA CTD PMID:27935865 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
JBrowse link
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of CAMK2N1 mRNA] CTD PMID:29891994 NCBI chr 5:150,674,819...150,676,600
Ensembl chr 5:150,673,507...150,676,600
JBrowse link
G Card10 caspase recruitment domain family, member 10 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of CARD10 mRNA] CTD PMID:29891994 NCBI chr 7:110,330,460...110,371,551
Ensembl chr 7:110,330,408...110,359,224
JBrowse link
G Cbx4 chromobox 4 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of CBX4 mRNA] CTD PMID:29891994 NCBI chr10:104,337,140...104,343,210 JBrowse link
G Ccdc42 coiled-coil domain containing 42 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CCDC42 mRNA CTD PMID:27935865 NCBI chr10:53,289,956...53,300,135
Ensembl chr10:53,289,956...53,300,135
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CCL2 mRNA CTD PMID:27935865 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CCL3 mRNA CTD PMID:27935865 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CCL7 mRNA CTD PMID:27935865 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccna1 cyclin A1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CCNA1 mRNA; XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of CCNA1 mRNA] CTD PMID:27935865 PMID:29891994 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
JBrowse link
G Ccno cyclin O multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CCNO mRNA CTD PMID:27935865 NCBI chr 2:44,630,640...44,633,914
Ensembl chr 2:44,626,369...44,633,914
JBrowse link
G Cd177 CD177 molecule multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CD177 mRNA CTD PMID:27935865 NCBI chr 1:80,340,034...80,360,599
Ensembl chr 1:80,340,034...80,360,621
JBrowse link
G Cd5l Cd5 molecule-like multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CD5L mRNA CTD PMID:27935865 NCBI chr 2:172,791,007...172,802,018 JBrowse link
G Cdc20b cell division cycle 20B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CDC20B mRNA CTD PMID:27935865 NCBI chr 2:44,688,349...44,738,056 JBrowse link
G Cdh26 cadherin 26 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CDH26 mRNA CTD PMID:27935865 NCBI chr 3:165,520,523...165,573,191
Ensembl chr 3:165,520,439...165,572,149
JBrowse link
G Cdhr1 cadherin-related family member 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CDHR1 mRNA CTD PMID:27935865 NCBI chr16:12,843,436...12,863,321
Ensembl chr16:12,843,437...12,863,396
JBrowse link
G Celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CELSR3 mRNA CTD PMID:27935865 NCBI chr 8:109,530,597...109,558,360
Ensembl chr 8:109,530,641...109,558,354
JBrowse link
G Cfd complement factor D multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CFD mRNA CTD PMID:27935865 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
JBrowse link
G Chi3l1 chitinase 3 like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CHIL1 mRNA CTD PMID:27935865 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
JBrowse link
G Chodl chondrolectin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CHODL mRNA CTD PMID:27935865 NCBI chr11:17,654,137...17,676,450
Ensembl chr11:17,654,206...17,676,441
JBrowse link
G Chrdl1 chordin-like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CHRDL1 mRNA CTD PMID:27935865 NCBI chr  X:106,889,125...106,992,937
Ensembl chr  X:106,889,125...106,992,921
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CHRM2 mRNA CTD PMID:27935865 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
JBrowse link
G Cidec cell death-inducing DFFA-like effector c multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CIDEC mRNA CTD PMID:27935865 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CKMT2 mRNA CTD PMID:27935865 NCBI chr 2:23,079,920...23,110,518
Ensembl chr 2:23,079,918...23,110,430
JBrowse link
G Clec4d C-type lectin domain family 4, member D multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CLEC4D mRNA CTD PMID:27935865 NCBI chr 4:156,589,591...156,598,969
Ensembl chr 4:156,589,792...156,598,848
JBrowse link
G Clec4e C-type lectin domain family 4, member E multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CLEC4E mRNA CTD PMID:27935865 NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767
JBrowse link
G Cnn1 calponin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CNN1 mRNA CTD PMID:27935865 NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098
JBrowse link
G Cntfr ciliary neurotrophic factor receptor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CNTFR mRNA CTD PMID:27935865 NCBI chr 5:56,823,448...56,861,075
Ensembl chr 5:56,823,965...56,841,392
JBrowse link
G Colq collagen like tail subunit of asymmetric acetylcholinesterase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of COLQ mRNA CTD PMID:27935865 NCBI chr16:6,731,850...6,824,973
Ensembl chr16:6,731,858...6,787,107
JBrowse link
G Cox7a1 cytochrome c oxidase subunit 7A1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of COX7A1 mRNA CTD PMID:27935865 NCBI chr 1:85,422,162...85,447,530
Ensembl chr 1:85,441,871...85,445,151
JBrowse link
G Cplx1 complexin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CPLX1 mRNA CTD PMID:27935865 NCBI chr14:1,184,638...1,216,392 JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of CREB1 mRNA] CTD PMID:29891994 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CREB3L3 mRNA CTD PMID:27935865 NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048
JBrowse link
G Crispld1 cysteine-rich secretory protein LCCL domain containing 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CRISPLD1 mRNA CTD PMID:27935865 NCBI chr 5:1,267,347...1,314,926
Ensembl chr 5:1,274,647...1,314,926
JBrowse link
G Cryl1 crystallin, lambda 1 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of CRYL1 mRNA] CTD PMID:29891994 NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997
JBrowse link
G Csf3 colony stimulating factor 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CSF3 mRNA CTD PMID:27935865 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Csf3r colony stimulating factor 3 receptor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CSF3R mRNA CTD PMID:27935865 NCBI chr 5:138,298,605...138,318,224
Ensembl chr 5:138,301,506...138,317,881
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of CSRP1 mRNA] CTD PMID:29891994 NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
JBrowse link
G Ctsc cathepsin C multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of CTSC mRNA] CTD PMID:29891994 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CXCL12 mRNA CTD PMID:27935865 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CXCL2 mRNA CTD PMID:27935865 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CXCL3 mRNA CTD PMID:27935865 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CXCR2 mRNA CTD PMID:27935865 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
JBrowse link
G Cxx1a CAAX box 1A multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of RTL8A mRNA] CTD PMID:29891994
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CYP2E1 mRNA CTD PMID:27935865 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CYP4F18 mRNA CTD PMID:27935865 NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940
JBrowse link
G Cys1 cystin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CYS1 mRNA CTD PMID:27935865 NCBI chr 6:41,300,836...41,318,071
Ensembl chr 6:41,300,836...41,318,071
JBrowse link
G Dcaf12l1 DDB1 and CUL4 associated factor 12-like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of DCAF12L1 mRNA CTD PMID:27935865 NCBI chr  X:123,695,286...123,698,905
Ensembl chr  X:123,695,286...123,698,905
JBrowse link
G Dchs1 dachsous cadherin-related 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of DCHS1 mRNA CTD PMID:27935865 NCBI chr 1:160,104,931...160,138,958
Ensembl chr 1:160,104,931...160,124,808
JBrowse link
G Degs2 delta(4)-desaturase, sphingolipid 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of DEGS2 mRNA CTD PMID:27935865 NCBI chr 6:127,596,063...127,613,293
Ensembl chr 6:127,596,071...127,613,293
JBrowse link
G Derl3 derlin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of DERL3 mRNA CTD PMID:27935865 NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027
JBrowse link
G Dhdh dihydrodiol dehydrogenase multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of DHDH mRNA] CTD PMID:29891994 NCBI chr 1:95,954,361...95,965,262
Ensembl chr 1:95,953,092...95,965,197
JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of DMBT1 mRNA; XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of DMBT1 mRNA] CTD PMID:27935865 PMID:29891994 NCBI chr 1:185,617,469...185,696,476 JBrowse link
G Dmrta1 DMRT-like family A1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of DMRTA1 mRNA CTD PMID:27935865 NCBI chr 5:104,415,893...104,422,433
Ensembl chr 5:104,415,893...104,422,433
JBrowse link
G Dpt dermatopontin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of DPT mRNA CTD PMID:27935865 NCBI chr13:77,122,926...77,151,646
Ensembl chr13:77,123,115...77,151,639
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of DRD1 mRNA CTD PMID:27935865 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Edn3 endothelin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of EDN3 mRNA CTD PMID:27935865 NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093
JBrowse link
G Eef1a2 eukaryotic translation elongation factor 1 alpha 2 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of EEF1A2 mRNA] CTD PMID:29891994 NCBI chr 3:168,265,893...168,275,071 JBrowse link
G Egf epidermal growth factor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of EGF mRNA CTD PMID:27935865 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Epha3 Eph receptor A3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of EPHA3 mRNA CTD PMID:27935865 NCBI chr11:1,138,485...1,474,102
Ensembl chr11:1,140,985...1,473,900
JBrowse link
G Epha5 EPH receptor A5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of EPHA5 mRNA CTD PMID:27935865 NCBI chr14:23,653,393...24,020,135
Ensembl chr14:23,653,393...24,017,317
JBrowse link
G Epyc epiphycan multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of EPYC mRNA CTD PMID:27935865 NCBI chr 7:32,436,620...32,474,326
Ensembl chr 7:32,436,620...32,474,135
JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of F2RL1 mRNA] CTD PMID:29891994 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of F2RL3 mRNA CTD PMID:27935865 NCBI chr16:17,117,441...17,119,434
Ensembl chr16:17,117,441...17,119,472
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of F3 mRNA] CTD PMID:29891994 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fam13c family with sequence similarity 13, member C multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of FAM13C mRNA CTD PMID:27935865 NCBI chr20:18,065,625...18,187,653
Ensembl chr20:18,065,628...18,187,592
JBrowse link
G Fam240b family with sequence similarity 240 member B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of FAM240B mRNA CTD PMID:27935865 NCBI chr17:657,248...663,209
Ensembl chr17:657,303...663,206
JBrowse link
G Fat2 FAT atypical cadherin 2 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of FAT2 mRNA] CTD PMID:29891994 NCBI chr10:39,364,072...39,456,324
Ensembl chr10:39,364,073...39,456,216
JBrowse link
G Fbln7 fibulin 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of FBLN7 mRNA CTD PMID:27935865 NCBI chr 3:116,111,581...116,145,839
Ensembl chr 3:116,111,677...116,147,983
JBrowse link
G Fbxo40 F-box protein 40 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of FBXO40 mRNA CTD PMID:27935865 NCBI chr11:63,794,452...63,812,697
Ensembl chr11:63,794,624...63,812,697
JBrowse link
G Fcrl2 Fc receptor-like 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of FCRLS mRNA CTD PMID:27935865 NCBI chr 2:172,694,308...172,707,261
Ensembl chr 2:172,694,308...172,707,051
JBrowse link
G Fhod3 formin homology 2 domain containing 3 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of FHOD3 mRNA] CTD PMID:29891994 NCBI chr18:15,993,079...16,425,796
Ensembl chr18:15,993,324...16,425,796
JBrowse link
G Foxn4 forkhead box N4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of FOXN4 mRNA CTD PMID:27935865 NCBI chr12:42,336,706...42,359,932
Ensembl chr12:42,340,323...42,359,921
JBrowse link
G Fpr2 formyl peptide receptor 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of FPR2 mRNA CTD PMID:27935865 NCBI chr 1:58,776,592...58,785,227
Ensembl chr 1:58,776,752...58,786,019
JBrowse link
G Frem1 Fras1 related extracellular matrix 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of FREM1 mRNA CTD PMID:27935865 NCBI chr 5:97,321,275...97,469,523
Ensembl chr 5:97,322,538...97,469,543
JBrowse link
G Frmpd4 FERM and PDZ domain containing 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of FRMPD4 mRNA CTD PMID:27935865 NCBI chr  X:25,853,849...26,814,642
Ensembl chr  X:25,853,934...26,814,637
JBrowse link
G Frzb frizzled-related protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of FRZB mRNA CTD PMID:27935865 NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208
JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of GABRA4 mRNA CTD PMID:27935865 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844
JBrowse link
G Gal3st2 galactose-3-O-sulfotransferase 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of GAL3ST2 mRNA CTD PMID:27935865 NCBI chr 9:94,382,456...94,387,990 JBrowse link
G Gask1a golgi associated kinase 1A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of GASK1A mRNA CTD PMID:27935865 NCBI chr 8:121,610,779...121,643,742
Ensembl chr 8:121,610,787...121,642,942
JBrowse link
G Gcnt4 glucosaminyl (N-acetyl) transferase 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of GCNT4 mRNA CTD PMID:27935865 NCBI chr 2:28,253,311...28,329,381 JBrowse link
G Gdf10 growth differentiation factor 10 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of GDF10 mRNA CTD PMID:27935865 NCBI chr16:9,237,182...9,250,537
Ensembl chr16:9,237,261...9,249,343
JBrowse link
G Gfra3 GDNF family receptor alpha 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of GFRA3 mRNA CTD PMID:27935865 NCBI chr18:26,297,828...26,326,105
Ensembl chr18:26,297,829...26,326,105
JBrowse link
G Gja3 gap junction protein, alpha 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of GJA3 mRNA CTD PMID:27935865 NCBI chr15:31,181,360...31,206,808
Ensembl chr15:31,181,369...31,206,810
JBrowse link
G Gprasp2 G protein-coupled receptor associated sorting protein 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of GPRASP2 mRNA CTD PMID:27935865 NCBI chr  X:98,817,669...98,823,814
Ensembl chr  X:98,817,593...98,824,402
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of GSTK1 mRNA] CTD PMID:29891994 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of GSTZ1 mRNA] CTD PMID:29891994 NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284
JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of HES1 mRNA] CTD PMID:29891994 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192