Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:naphthyridine
go back to main search page
Accession:CHEBI:36624 term browser browse the term
Definition:Any one of eight organic heterobicyclic compounds that have a naphthalene skeleton in which two of the carbons are replaced by nitrogens. A 'closed' class.
Synonyms:related_synonym: Formula=C8H6N2
 xref: Wikipedia:Naphthyridine


show annotations for term's descendants           Sort by:
 
6,7-dimethoxy-2-phenylquinoxaline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [PDGFB protein results in increased phosphorylation of AKT1 protein] CTD PMID:25896968 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein] CTD PMID:25896968 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein] CTD PMID:25896968 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions ISO 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [Nicotine results in increased expression of PDGFB mRNA]; 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [Nicotine results in increased secretion of PDGFB protein]; 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [PDGFB protein results in increased phosphorylation of AKT1 protein]; 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]; 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]; 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [PDGFB protein results in increased phosphorylation of PDGFRB protein]; 6,7-dimethoxy-2-phenylquinoxaline results in decreased susceptibility to [PDGFB protein binds to PDGFB protein] CTD PMID:16149045, PMID:23457620, PMID:25896968 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions ISO 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [Nicotine results in increased expression of PDGFRB protein]; 6,7-dimethoxy-2-phenylquinoxaline inhibits the reaction [PDGFB protein results in increased phosphorylation of PDGFRB protein] CTD PMID:16149045, PMID:25896968 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
6-Cyano-7-nitroquinoxaline-2,3-dione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco2 aconitase 2 multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Kainic Acid results in decreased activity of ACO2 protein] CTD PMID:11520895 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Pilocarpine results in increased expression of BDNF mRNA alternative form] CTD PMID:15183516 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Casp3 caspase 3 multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid inhibits the reaction [Phencyclidine results in increased activity of CASP3 protein]] CTD PMID:24995437 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Capsaicin results in increased expression of FOS] CTD PMID:10401552 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein] CTD PMID:21863293 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione results in increased expression of and results in increased localization of GRIA1 protein CTD PMID:19674091 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione results in increased expression of and results in increased localization of GRIA2 protein CTD PMID:19674091 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP
6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein]
6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]
CTD PMID:15385614, PMID:19850060 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO
EXP
6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK3 protein]
6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]
CTD PMID:15385614, PMID:19850060 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nefl neurofilament light multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFL protein] CTD PMID:21863293 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Nefm neurofilament medium multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFM protein] CTD PMID:21863293 NCBI chr15:44,855,307...44,860,604
Ensembl chr15:44,855,310...44,860,604
JBrowse link
G Sct secretin multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [SCT protein results in increased secretion of gamma-Aminobutyric Acid] CTD PMID:15963647 NCBI chr 1:214,264,865...214,277,437
Ensembl chr 1:214,264,754...214,265,668
JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [L 703606 results in increased activity of TAC1 protein] CTD PMID:14985054 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Vim vimentin multiple interactions EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [diphenylditelluride results in decreased phosphorylation of VIM protein] CTD PMID:21863293 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
brimonidine tartrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A multiple interactions ISO
EXP
Brimonidine Tartrate inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; Brimonidine Tartrate promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA2A protein]; Phenylephrine promotes the reaction [Brimonidine Tartrate binds to and results in increased activity of ADRA2A protein]; Prazosin inhibits the reaction [Phenylephrine promotes the reaction [Brimonidine Tartrate binds to and results in increased activity of ADRA2A protein]]; Yohimbine inhibits the reaction [Brimonidine Tartrate promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA2A protein]] CTD PMID:8397342, PMID:10742289, PMID:12208771, PMID:12598592 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Agt angiotensinogen multiple interactions EXP 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; bisindolylmaleimide I inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; bisindolylmaleimide I inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]; Brimonidine Tartrate promotes the reaction [AGT protein results in increased activity of RHOA protein]; diphenyleneiodonium inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; diphenyleneiodonium inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]] CTD PMID:18250367 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO Brimonidine Tartrate inhibits the reaction [CFTR protein affects the transport of Chlorides] CTD PMID:12598592 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation EXP Brimonidine Tartrate results in increased phosphorylation of CREB1 protein CTD PMID:17680988 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Prkca protein kinase C, alpha affects localization
multiple interactions
EXP Brimonidine Tartrate affects the localization of PRKCA protein
Nitric Oxide deficiency promotes the reaction [Brimonidine Tartrate affects the localization of PRKCA protein]
CTD PMID:12388232 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Prkcd protein kinase C, delta affects localization
multiple interactions
EXP Brimonidine Tartrate affects the localization of PRKCD protein
Nitric Oxide deficiency inhibits the reaction [Brimonidine Tartrate affects the localization of PRKCD protein]
CTD PMID:12388232 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Rhoa ras homolog family member A multiple interactions EXP 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; bisindolylmaleimide I inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; Brimonidine Tartrate promotes the reaction [AGT protein results in increased activity of RHOA protein]; diphenyleneiodonium inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]] CTD PMID:18250367 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Brimonidine Tartrate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
cyclazosin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1b adrenoceptor alpha 1B multiple interactions EXP cyclazosin binds to and results in decreased activity of ADRA1B protein CTD PMID:15951348 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644
JBrowse link
enoxacin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
affects binding
decreases activity
ISO
EXP
Enoxacin inhibits the reaction [CYP1A2 protein affects the metabolism of Fluvoxamine]; Enoxacin inhibits the reaction [CYP1A2 protein results in increased metabolism of Tacrine]; NADP promotes the reaction [Enoxacin inhibits the reaction [CYP1A2 protein results in increased metabolism of Tacrine]]
Enoxacin inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin]
Enoxacin binds to CYP1A2 protein
Enoxacin results in decreased activity of CYP1A2 protein
CTD PMID:7946932, PMID:8905919, PMID:15905806 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Enoxacin inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions ISO 7-nitroindazole inhibits the reaction [[Enoxacin co-treated with fenbufen] results in increased activity of NOS1 protein]; [Enoxacin co-treated with fenbufen] results in increased activity of NOS1 protein CTD PMID:9623721 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
MK-2206 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions
decreases expression
ISO [gamma-mangostin co-treated with MK 2206] results in decreased expression of ACTA2 protein
MK 2206 results in decreased expression of ACTA2 protein
CTD PMID:30502394 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Agt angiotensinogen multiple interactions ISO MK 2206 inhibits the reaction [AGT protein modified form results in increased secretion of IL6 protein]; MK 2206 inhibits the reaction [AGT protein modified form results in increased secretion of TNF protein] CTD PMID:30354818 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
increases phosphorylation
multiple interactions
ISO
EXP
MK 2206 results in decreased phosphorylation of AKT1 protein
MK 2206 results in increased phosphorylation of AKT1 protein
[gamma-mangostin co-treated with MK 2206] results in decreased phosphorylation of AKT1 protein; [PD 0325901 co-treated with MK 2206] results in increased phosphorylation of AKT1 protein; MK 2206 inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of AKT1 protein]; MK 2206 inhibits the reaction [PNPLA2 protein results in increased phosphorylation of AKT1 protein]; MK 2206 results in decreased phosphorylation of and results in decreased activity of AKT1 protein; romidepsin inhibits the reaction [[PD 0325901 co-treated with MK 2206] results in increased phosphorylation of AKT1 protein]
MK 2206 inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of and results in increased expression of AKT1 protein]; MK 2206 inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]]
LEPR affects the reaction [MK 2206 results in decreased phosphorylation of AKT1 protein]
CTD PMID:22885370, PMID:22949526, PMID:24685774, PMID:25597859, PMID:27634878, PMID:27897231, PMID:29669060, PMID:30502394, PMID:30723155, PMID:31445927, PMID:31476254 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt1s1 AKT1 substrate 1 decreases phosphorylation
multiple interactions
ISO MK 2206 results in decreased phosphorylation of AKT1S1 protein
[STO 609 co-treated with MK 2206] results in decreased phosphorylation of AKT1S1 protein
CTD PMID:28634229 NCBI chr 1:100,845,443...100,851,961
Ensembl chr 1:100,845,563...100,851,960
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO MK 2206 inhibits the reaction [Cadmium Chloride results in increased expression of ATF4] CTD PMID:24057571 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO MK 2206 inhibits the reaction [Dexamethasone results in increased phosphorylation of BAD protein] CTD PMID:30878453 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions ISO [PD 0325901 co-treated with MK 2206] results in increased expression of BAK1 protein; [romidepsin co-treated with MK 2206] results in increased expression of BAK1 protein; [romidepsin co-treated with PD 0325901 co-treated with MK 2206] results in increased expression of BAK1 protein CTD PMID:27634878 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bcl2l11 BCL2 like 11 multiple interactions ISO [PD 0325901 co-treated with MK 2206] results in increased expression of BCL2L11 protein; [romidepsin co-treated with MK 2206] results in increased expression of BCL2L11 protein; [romidepsin co-treated with PD 0325901 co-treated with MK 2206] results in increased expression of BCL2L11 protein CTD PMID:27634878 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [PD 0325901 co-treated with MK 2206] results in increased expression of BID mRNA; [PD 0325901 co-treated with MK 2206] results in increased expression of BID protein modified form CTD PMID:28691888 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
ISO MK 2206 results in increased cleavage of CASP3 protein
MK 2206 inhibits the reaction [Dexamethasone results in increased cleavage of CASP3 protein]
[MK 2206 co-treated with platycodin D] results in increased activity of CASP3 protein; MK 2206 inhibits the reaction [Soot analog results in increased expression of CASP3 protein]
CTD PMID:22885370, PMID:27897231, PMID:30240709, PMID:30878453 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 multiple interactions ISO [MK 2206 co-treated with platycodin D] results in increased activity of CASP7 protein CTD PMID:27897231 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp9 caspase 9 multiple interactions ISO MK 2206 inhibits the reaction [Soot analog results in increased expression of CASP9 protein] CTD PMID:30240709 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cdh1 cadherin 1 multiple interactions
increases expression
ISO [MK 2206 co-treated with U 0126] results in increased expression of CDH1 mRNA
MK 2206 results in increased expression of CDH1 mRNA
CTD PMID:30723155 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Egfr epidermal growth factor receptor increases expression
multiple interactions
ISO MK 2206 results in increased expression of EGFR protein
platycodin D inhibits the reaction [MK 2206 results in increased expression of EGFR protein]
CTD PMID:27897231 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 decreases phosphorylation
multiple interactions
ISO MK 2206 results in decreased phosphorylation of EIF4EBP1 protein
[platycodin D co-treated with MK 2206] results in decreased phosphorylation of EIF4EBP1 protein
CTD PMID:22885370, PMID:27897231 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions
increases expression
ISO platycodin D inhibits the reaction [MK 2206 results in increased expression of ERBB2 protein] CTD PMID:27897231 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO MK 2206 promotes the reaction [Cadmium Chloride results in increased expression of ERN1 protein] CTD PMID:29444456 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO MK 2206 results in increased expression of F3 protein CTD PMID:25569083 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fas Fas cell surface death receptor affects response to substance ISO MK 2206 affects the susceptibility to FAS protein CTD PMID:31445927 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP
ISO
MK 2206 inhibits the reaction [Diethylhexyl Phthalate results in increased expression of FN1 protein]
[MK 2206 co-treated with U 0126] results in decreased expression of FN1 mRNA
CTD PMID:29669060, PMID:30723155 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP MK 2206 inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of GSK3B protein] CTD PMID:29669060 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions EXP MK 2206 inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]] CTD PMID:25597859 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO MK 2206 inhibits the reaction [Particulate Matter results in increased expression of IL1B mRNA]; MK 2206 inhibits the reaction [Particulate Matter results in increased secretion of IL1B protein] CTD PMID:31018152 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO MK 2206 inhibits the reaction [AGT protein modified form results in increased secretion of IL6 protein] CTD PMID:30354818 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Lep leptin multiple interactions ISO MK 2206 inhibits the reaction [8-(4-chlorophenylthio)-2'-O-methyladenosine-3',5'-monophosphate acetoxymethyl ester analog results in increased secretion of LEP protein] CTD PMID:27381457 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lepr leptin receptor multiple interactions ISO LEPR affects the reaction [MK 2206 results in decreased phosphorylation of AKT1 protein] CTD PMID:22949526 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions ISO MK 2206 promotes the reaction [Cadmium Chloride results in increased expression of MAP3K5 protein] CTD PMID:29444456 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
ISO U 0126 promotes the reaction [MK 2206 results in decreased phosphorylation of MAPK1 protein]
[MK 2206 co-treated with PD 0325901] results in decreased phosphorylation of MAPK1 protein
CTD PMID:27634878, PMID:30723155 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation
multiple interactions
ISO MK 2206 results in decreased phosphorylation of MAPK3 protein
[MK 2206 co-treated with PD 0325901] results in decreased phosphorylation of MAPK3 protein
U 0126 promotes the reaction [MK 2206 results in decreased phosphorylation of MAPK3 protein]
CTD PMID:27634878, PMID:30723155 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions ISO [PD 0325901 co-treated with MK 2206] results in increased expression of MCL1 protein; [romidepsin co-treated with MK 2206] results in increased expression of MCL1 protein; [romidepsin co-treated with PD 0325901 co-treated with MK 2206] results in increased expression of MCL1 protein CTD PMID:27634878 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO MTOR gene mutant form promotes the reaction [MK 2206 results in decreased expression of RPS6 protein modified form] CTD PMID:29384525 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [PD 0325901 co-treated with MK 2206] results in increased cleavage of PARP1 protein; [romidepsin co-treated with MK 2206] results in increased cleavage of PARP1 protein; romidepsin promotes the reaction [[PD 0325901 co-treated with MK 2206] results in increased cleavage of PARP1 protein] CTD PMID:27634878 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 multiple interactions ISO MK 2206 inhibits the reaction [PNPLA2 protein results in increased phosphorylation of AKT1 protein] CTD PMID:31476254 NCBI chr 1:214,434,638...214,439,720
Ensembl chr 1:214,434,626...214,439,720
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO MK 2206 inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 protein]; MK 2206 inhibits the reaction [Taurocholic Acid results in increased expression of PTGS2 protein] CTD PMID:26518876 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation
decreases expression
multiple interactions
ISO MK 2206 results in decreased phosphorylation of RPS6 protein
MK 2206 results in decreased expression of RPS6 protein modified form
MTOR gene mutant form promotes the reaction [MK 2206 results in decreased expression of RPS6 protein modified form]
CTD PMID:22885370, PMID:29384525 NCBI chr 5:105,197,821...105,200,681
Ensembl chr 5:105,197,857...105,200,148
JBrowse link
G Slc12a3 solute carrier family 12 member 3 multiple interactions ISO MK 2206 inhibits the reaction [INS1 protein results in increased phosphorylation of SLC12A3 protein] CTD PMID:22949526 NCBI chr19:11,106,033...11,144,674
Ensembl chr19:11,106,033...11,144,641
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions
decreases expression
ISO [U 0126 co-treated with MK 2206] results in decreased expression of SNAI1 mRNA
MK 2206 results in decreased expression of SNAI1 mRNA
CTD PMID:30723155 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Snai2 snail family transcriptional repressor 2 multiple interactions ISO [U 0126 co-treated with MK 2206] results in decreased expression of SNAI2 mRNA CTD PMID:30723155 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO MK 2206 binds to and results in increased activity of THRB protein CTD PMID:25752796 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases response to substance
ISO MK 2206 inhibits the reaction [1-nitropyrene results in increased expression of TNF mRNA]; MK 2206 inhibits the reaction [3-nitrofluoranthene results in increased expression of TNF mRNA]; MK 2206 inhibits the reaction [AGT protein modified form results in increased secretion of TNF protein]
MK 2206 results in increased susceptibility to TNF protein
CTD PMID:28633978, PMID:30354818, PMID:31445927 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [PD 0325901 co-treated with MK 2206] results in increased expression of and results in increased phosphorylation of TRP53 protein CTD PMID:28691888 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Vim vimentin multiple interactions EXP MK 2206 inhibits the reaction [Diethylhexyl Phthalate results in increased expression of VIM protein] CTD PMID:29669060 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO MK 2206 promotes the reaction [Cadmium Chloride results in increased expression of XBP1 protein alternative form] CTD PMID:29444456 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 multiple interactions
increases expression
ISO [U 0126 co-treated with MK 2206] results in increased expression of ZEB1 mRNA
MK 2206 results in increased expression of ZEB1 mRNA
CTD PMID:30723155 NCBI chr17:54,656,627...54,714,920
Ensembl chr17:54,658,463...54,714,914
JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 multiple interactions
decreases expression
ISO [U 0126 co-treated with MK 2206] results in decreased expression of ZEB2 mRNA
MK 2206 results in decreased expression of ZEB2 mRNA
CTD PMID:30723155 NCBI chr 3:29,857,289...29,985,932
Ensembl chr 3:29,862,473...29,996,865
JBrowse link
nalidixic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta multiple interactions ISO Nalidixic Acid inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA] CTD PMID:16148020 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions
decreases expression
ISO Nalidixic Acid inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]
Nalidixic Acid results in decreased expression of MMP13 mRNA
CTD PMID:16148020 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
quinalphos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO quinalphos binds to and results in increased activity of AHR protein CTD PMID:18835618 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ar androgen receptor multiple interactions ISO Dihydrotestosterone inhibits the reaction [quinalphos results in increased activity of AR protein] CTD PMID:15064155 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Bche butyrylcholinesterase decreases activity
multiple interactions
ISO quinalphos results in decreased activity of BCHE protein
pralidoxime inhibits the reaction [quinalphos results in decreased activity of BCHE protein]
CTD PMID:24052565 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Cat catalase multiple interactions
decreases activity
ISO Plant Extracts inhibits the reaction [quinalphos results in decreased activity of CAT protein] CTD PMID:24581381 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases expression
multiple interactions
ISO quinalphos results in decreased expression of CYP26B1 mRNA
Plant Extracts inhibits the reaction [quinalphos results in decreased expression of CYP26B1 mRNA]
CTD PMID:24581381 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615
JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO quinalphos results in increased activity of ESR1 protein CTD PMID:15064155 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 increases activity ISO quinalphos results in increased activity of ESR2 protein CTD PMID:15064155 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
affects activity
EXP [Monocrotophos co-treated with quinalphos] affects the activity of G6PD protein
quinalphos affects the activity of G6PD protein
CTD PMID:24248738 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
affects activity
EXP [Monocrotophos co-treated with quinalphos] affects the activity of GSR protein
quinalphos affects the activity of GSR protein
CTD PMID:24248738 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 multiple interactions
decreases expression
ISO Plant Extracts inhibits the reaction [quinalphos results in decreased expression of HSD3B3 mRNA] CTD PMID:24581381 NCBI chr 2:200,756,557...200,762,492
Ensembl chr 2:200,585,748...200,762,492
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO quinalphos binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
decreases expression
ISO Plant Extracts inhibits the reaction [quinalphos results in decreased expression of STAR mRNA]; Plant Extracts inhibits the reaction [quinalphos results in decreased expression of STAR protein]
quinalphos results in decreased expression of STAR mRNA; quinalphos results in decreased expression of STAR protein
CTD PMID:24581381 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
quinomethionate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btg2 BTG anti-proliferation factor 2 affects expression ISO quinomethionate affects the expression of BTG2 mRNA CTD PMID:15387888 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta affects expression ISO quinomethionate affects the expression of CEBPD mRNA CTD PMID:15387888 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 affects expression ISO quinomethionate affects the expression of CXCL2 mRNA CTD PMID:15387888 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Etv4 ETS variant transcription factor 4 affects expression ISO quinomethionate affects the expression of ETV4 mRNA CTD PMID:15387888 NCBI chr10:89,685,058...89,700,300
Ensembl chr10:89,685,058...89,700,283
JBrowse link
G Ewsr1 EWS RNA-binding protein 1 affects expression ISO quinomethionate affects the expression of EWSR1 mRNA CTD PMID:15387888 NCBI chr14:85,322,105...85,350,826
Ensembl chr14:85,322,296...85,350,948
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 affects expression ISO quinomethionate affects the expression of FKBP5 mRNA CTD PMID:15387888 NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit affects expression ISO quinomethionate affects the expression of FOS mRNA CTD PMID:15387888 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha affects expression ISO quinomethionate affects the expression of GADD45A mRNA CTD PMID:15387888 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Hnrnpf heterogeneous nuclear ribonucleoprotein F affects expression ISO quinomethionate affects the expression of HNRNPF mRNA CTD PMID:15387888 NCBI chr 4:149,957,143...149,978,896
Ensembl chr 4:149,957,206...149,978,895
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit affects expression ISO quinomethionate affects the expression of JUNB mRNA CTD PMID:15387888 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit affects expression ISO quinomethionate affects the expression of JUND mRNA CTD PMID:15387888 NCBI chr16:20,485,028...20,486,707
Ensembl chr16:20,485,029...20,486,707
JBrowse link
G Lmnb1 lamin B1 affects expression ISO quinomethionate affects the expression of LMNB1 mRNA CTD PMID:15387888 NCBI chr18:51,785,111...51,822,264
Ensembl chr18:51,785,111...51,822,264
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 affects expression ISO quinomethionate affects the expression of MAP2K1 mRNA CTD PMID:15387888 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Mat2a methionine adenosyltransferase 2A affects expression ISO quinomethionate affects the expression of MAT2A mRNA CTD PMID:15387888 NCBI chr 4:100,297,478...100,303,047
Ensembl chr 4:100,296,075...100,303,080
JBrowse link
G Nfkbia NFKB inhibitor alpha affects expression ISO quinomethionate affects the expression of NFKBIA mRNA CTD PMID:15387888 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Phb prohibitin affects expression ISO quinomethionate affects the expression of PHB mRNA CTD PMID:15387888 NCBI chr10:83,476,107...83,488,878
Ensembl chr10:83,476,107...83,488,878
JBrowse link
G Ppib peptidylprolyl isomerase B affects expression ISO quinomethionate affects the expression of PPIB mRNA CTD PMID:15387888 NCBI chr 8:71,719,681...71,725,538
Ensembl chr 8:71,719,563...71,725,562
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase affects expression ISO quinomethionate affects the expression of RAF1 mRNA CTD PMID:15387888 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Rarg retinoic acid receptor, gamma affects expression ISO quinomethionate affects the expression of RARG mRNA CTD PMID:15387888 NCBI chr 7:143,840,739...143,863,206
Ensembl chr 7:143,839,980...143,863,186
JBrowse link
G Rbm39 RNA binding motif protein 39 affects expression ISO quinomethionate affects the expression of RBM39 mRNA CTD PMID:15387888 NCBI chr 3:151,691,498...151,724,723
Ensembl chr 3:151,691,514...151,724,654
JBrowse link
G Rnd3 Rho family GTPase 3 affects expression ISO quinomethionate affects the expression of RND3 mRNA CTD PMID:15387888 NCBI chr 3:36,643,374...36,660,727
Ensembl chr 3:36,642,587...36,660,758
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 affects expression ISO quinomethionate affects the expression of SUMO1 mRNA CTD PMID:15387888 NCBI chr 9:66,453,428...66,483,614
Ensembl chr 9:66,453,438...66,483,614
JBrowse link
G Tgfa transforming growth factor alpha affects expression ISO quinomethionate affects the expression of TGFA mRNA CTD PMID:15387888 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344
JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 affects expression ISO quinomethionate affects the expression of UQCRC2 mRNA CTD PMID:15387888 NCBI chr 1:190,555,177...190,585,741
Ensembl chr 1:190,555,177...190,585,734
JBrowse link
G Vegfa vascular endothelial growth factor A affects expression ISO quinomethionate affects the expression of VEGFA mRNA CTD PMID:15387888 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
quizalofop-ethyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox1 acyl-CoA oxidase 1 increases activity
increases expression
multiple interactions
EXP quizalofop-ethyl analog results in increased activity of ACOX1 protein
quizalofop-ethyl analog results in increased expression of ACOX1 mRNA
PPARA protein affects the reaction [quizalofop-ethyl analog results in increased activity of ACOX1 protein]; PPARA protein affects the reaction [quizalofop-ethyl analog results in increased expression of ACOX1 mRNA]
CTD PMID:29626562 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Cat catalase increases activity EXP quizalofop-ethyl analog results in increased activity of CAT protein CTD PMID:29626562 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases response to substance
multiple interactions
EXP PPARA protein results in increased susceptibility to quizalofop-ethyl analog
PPARA protein affects the reaction [quizalofop-ethyl analog results in increased activity of ACOX1 protein]; PPARA protein affects the reaction [quizalofop-ethyl analog results in increased expression of ACOX1 mRNA]
CTD PMID:29626562 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases activity ISO quizalofop-ethyl results in increased activity of PPARG protein CTD PMID:31086981 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
trovafloxacin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha decreases expression EXP trovafloxacin results in decreased expression of ACACA mRNA CTD PMID:24136188 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acsf2 acyl-CoA synthetase family member 2 decreases expression EXP trovafloxacin results in decreased expression of ACSF2 mRNA CTD PMID:24136188 NCBI chr10:82,284,719...82,326,771
Ensembl chr10:82,284,720...82,326,771
JBrowse link
G Actb actin, beta decreases expression EXP trovafloxacin results in decreased expression of ACTB mRNA CTD PMID:24136188 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Actg1 actin, gamma 1 decreases expression EXP trovafloxacin results in decreased expression of ACTG1 mRNA CTD PMID:24136188 NCBI chr10:109,518,429...109,521,288
Ensembl chr 3:75,643,054...75,644,954
Ensembl chr10:75,643,054...75,644,954
JBrowse link
G Acy1 aminoacylase 1 decreases expression EXP trovafloxacin results in decreased expression of ACY1 mRNA CTD PMID:24136188 NCBI chr 8:115,134,792...115,140,171
Ensembl chr 8:115,134,765...115,140,080
JBrowse link
G Adap2 ArfGAP with dual PH domains 2 increases expression EXP trovafloxacin results in increased expression of ADAP2 mRNA CTD PMID:24136188 NCBI chr10:67,494,851...67,527,582
Ensembl chr10:67,494,984...67,526,426
JBrowse link
G Adipor2 adiponectin receptor 2 decreases expression EXP trovafloxacin results in decreased expression of ADIPOR2 mRNA CTD PMID:24136188 NCBI chr 4:151,412,135...151,480,108
Ensembl chr 4:151,414,684...151,428,894
JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ADRB2 mRNA CTD PMID:18930950 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 decreases expression EXP trovafloxacin results in decreased expression of AKR7A3 mRNA CTD PMID:24136188 NCBI chr 5:157,801,120...157,813,756
Ensembl chr 5:157,801,163...157,813,756
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression EXP trovafloxacin results in decreased expression of ALDH1A1 mRNA CTD PMID:24136188 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 decreases expression EXP trovafloxacin results in decreased expression of ALDH1B1 mRNA CTD PMID:24136188 NCBI chr 5:61,382,351...61,387,359
Ensembl chr 5:61,382,351...61,387,358
JBrowse link
G Amd1 adenosylmethionine decarboxylase 1 decreases expression EXP trovafloxacin results in decreased expression of AMD1 mRNA CTD PMID:24136188 NCBI chr20:45,384,000...45,399,694
Ensembl chr20:45,384,000...45,399,694
JBrowse link
G Ammecr1l AMMECR1 like increases expression EXP trovafloxacin results in increased expression of AMMECR1L mRNA CTD PMID:24136188 NCBI chr18:24,539,530...24,563,576
Ensembl chr18:24,540,659...24,563,576
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ANGPTL4 mRNA CTD PMID:18930950 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Ankhd1 ankyrin repeat and KH domain containing 1 increases expression EXP trovafloxacin results in increased expression of ANKHD1-EIF4EBP3 mRNA CTD PMID:24136188 NCBI chr18:29,386,906...29,485,611
Ensembl chr18:29,386,809...29,492,718
JBrowse link
G Ap1s1 adaptor related protein complex 1 subunit sigma 1 decreases expression EXP trovafloxacin results in decreased expression of AP1S1 mRNA CTD PMID:24136188 NCBI chr12:22,665,128...22,676,079
Ensembl chr12:22,665,112...22,676,075
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of APEX1 mRNA CTD PMID:18930950 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Apoa5 apolipoprotein A5 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of APOA5 mRNA CTD PMID:18930950 NCBI chr 8:50,559,079...50,561,720
Ensembl chr 8:50,559,126...50,561,736
JBrowse link
G Arhgap24 Rho GTPase activating protein 24 decreases expression EXP trovafloxacin results in decreased expression of ARHGAP24 mRNA CTD PMID:24136188 NCBI chr14:8,383,211...8,600,526
Ensembl chr14:8,383,214...8,600,512
JBrowse link
G Arid5b AT-rich interaction domain 5B multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ARID5B mRNA CTD PMID:18930950 NCBI chr20:21,713,900...21,881,193
Ensembl chr20:21,564,975...21,880,715
JBrowse link
G Armt1 acidic residue methyltransferase 1 decreases expression EXP trovafloxacin results in decreased expression of ARMT1 mRNA CTD PMID:24136188 NCBI chr 1:40,982,761...41,006,371
Ensembl chr 1:40,982,862...41,006,371
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions
increases phosphorylation
ISO pyrazolanthrone inhibits the reaction [trovafloxacin results in increased phosphorylation of ATF2 protein] CTD PMID:24525298 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atp6v0e2 ATPase, H+ transporting V0 subunit e2 decreases expression EXP trovafloxacin results in decreased expression of ATP6V0E2 mRNA CTD PMID:24136188 NCBI chr 4:78,168,117...78,171,265
Ensembl chr 4:78,168,117...78,171,265
JBrowse link
G Atr ATR serine/threonine kinase multiple interactions ISO 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [[trovafloxacin co-treated with TNF protein] results in increased phosphorylation of ATR protein]; 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [trovafloxacin results in increased phosphorylation of ATR protein]; [trovafloxacin co-treated with TNF protein] results in increased phosphorylation of and results in increased activity of ATR protein; trovafloxacin results in increased phosphorylation of and results in increased activity of ATR protein; U 0126 inhibits the reaction [trovafloxacin results in increased activity of ATR protein] CTD PMID:25748550 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947
JBrowse link
G Atrn attractin increases expression EXP trovafloxacin results in increased expression of ATRN mRNA CTD PMID:24136188 NCBI chr 3:123,434,409...123,567,922
Ensembl chr 3:123,434,409...123,567,918
JBrowse link
G B2m beta-2 microglobulin multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of B2M mRNA CTD PMID:18930950 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of BHLHE40 mRNA CTD PMID:18930950 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions
decreases expression
ISO trovafloxacin inhibits the reaction [TNF protein results in increased expression of BIRC2 mRNA]
trovafloxacin results in decreased expression of BIRC2 protein
[trovafloxacin co-treated with TNF protein] results in decreased expression of BIRC2 mRNA
trovafloxacin results in decreased expression of BIRC2 mRNA
CTD PMID:32035082 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions
decreases expression
ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of BIRC3 mRNA
[trovafloxacin co-treated with TNF protein] results in increased expression of BIRC3 mRNA
trovafloxacin results in decreased expression of BIRC3 mRNA
CTD PMID:18930950, PMID:32035082 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Bpnt1 3'(2'), 5'-bisphosphate nucleotidase 1 decreases expression EXP trovafloxacin results in decreased expression of BPNT1 mRNA CTD PMID:24136188 NCBI chr13:103,268,045...103,292,848
Ensembl chr13:103,268,068...103,292,854
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 decreases expression EXP trovafloxacin results in decreased expression of BST2 mRNA CTD PMID:24136188 NCBI chr16:19,938,781...19,942,353
Ensembl chr16:19,938,784...19,942,353
JBrowse link
G Caprin1 cell cycle associated protein 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CAPRIN1 mRNA CTD PMID:18930950 NCBI chr 3:93,701,830...93,789,580
Ensembl chr 3:93,702,487...93,789,617
JBrowse link
G Casd1 CAS1 domain containing 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CASD1 mRNA CTD PMID:18930950 NCBI chr 4:29,638,280...29,693,151
Ensembl chr 4:29,639,154...29,691,928
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [trovafloxacin results in increased activity of CASP3 protein]; [TNF protein co-treated with trovafloxacin] results in increased activity of CASP3 protein; [trovafloxacin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [trovafloxacin co-treated with IL1B protein] results in increased activity of CASP3 protein; [trovafloxacin co-treated with IL6 protein] results in increased activity of CASP3 protein; [trovafloxacin co-treated with TNF protein] results in increased activity of CASP3 protein; U 0126 inhibits the reaction [[TNF protein co-treated with trovafloxacin] results in increased activity of CASP3 protein]
[TNF protein co-treated with trovafloxacin] results in increased cleavage of CASP3 protein
CTD PMID:19638433, PMID:24097668, PMID:25748550, PMID:30876886 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp6 caspase 6 increases expression EXP trovafloxacin results in increased expression of CASP6 mRNA CTD PMID:24136188 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp7 caspase 7 decreases expression EXP trovafloxacin results in decreased expression of CASP7 mRNA CTD PMID:24136188 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [trovafloxacin co-treated with TNF protein] results in increased activity of CASP8 protein CTD PMID:24097668 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions ISO [trovafloxacin co-treated with TNF protein] results in increased activity of CASP9 protein CTD PMID:24097668 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccdc6 coiled-coil domain containing 6 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CCDC6 mRNA CTD PMID:18930950 NCBI chr20:19,729,005...19,825,219
Ensembl chr20:19,732,894...19,825,150
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO trovafloxacin promotes the reaction [TNF protein results in increased expression of CCL2 protein] CTD PMID:19638433 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccnb2 cyclin B2 decreases expression EXP trovafloxacin results in decreased expression of CCNB2 mRNA CTD PMID:24136188 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP trovafloxacin results in decreased expression of CCND1 mRNA CTD PMID:24136188 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cd36 CD36 molecule decreases expression EXP trovafloxacin results in decreased expression of CD36 mRNA CTD PMID:24136188 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd8b CD8b molecule multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CD8B mRNA CTD PMID:18930950 NCBI chr 4:99,185,960...99,201,887
Ensembl chr 4:99,185,885...99,202,023
JBrowse link
G Cdc20 cell division cycle 20 decreases expression EXP trovafloxacin results in decreased expression of CDC20 mRNA CTD PMID:24136188 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdc42ep4 CDC42 effector protein 4 increases expression EXP trovafloxacin results in increased expression of CDC42EP4 mRNA CTD PMID:24136188 NCBI chr10:102,244,680...102,269,272
Ensembl chr10:102,244,681...102,269,272
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression EXP trovafloxacin results in decreased expression of CDK1 mRNA CTD PMID:24136188 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk16 cyclin-dependent kinase 16 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CDK16 mRNA CTD PMID:18930950 NCBI chr  X:1,707,285...1,718,821
Ensembl chr  X:1,707,289...1,718,637
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CDKN1A mRNA
trovafloxacin results in increased expression of CDKN1A mRNA
CTD PMID:18930950, PMID:25748550 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression EXP trovafloxacin results in decreased expression of CDKN3 mRNA CTD PMID:24136188 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CEBPA mRNA CTD PMID:18930950 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Chfr checkpoint with forkhead and ring finger domains multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CHFR mRNA CTD PMID:18930950 NCBI chr12:52,562,594...52,596,162
Ensembl chr12:52,562,597...52,596,076
JBrowse link
G Chka choline kinase alpha multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CHKA mRNA CTD PMID:18930950 NCBI chr 1:219,076,618...219,126,221
Ensembl chr 1:219,077,771...219,126,220
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression EXP trovafloxacin results in decreased expression of CKS2 mRNA CTD PMID:24136188 NCBI chr17:13,587,664...13,593,423
Ensembl chr17:13,587,665...13,593,423
JBrowse link
G Cldn14 claudin 14 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CLDN14 mRNA CTD PMID:18930950 NCBI chr11:34,132,581...34,142,813
Ensembl chr11:34,132,581...34,142,753
JBrowse link
G Clint1 clathrin interactor 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CLINT1 mRNA CTD PMID:18930950 NCBI chr10:30,833,914...31,007,813
Ensembl chr10:30,833,914...31,007,820
JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of COMT mRNA CTD PMID:18930950 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Copg1 COPI coat complex subunit gamma 1 decreases expression EXP trovafloxacin results in decreased expression of COPG1 mRNA CTD PMID:24136188 NCBI chr 4:119,815,041...119,840,997
Ensembl chr 4:119,815,139...119,864,114
JBrowse link
G Cpox coproporphyrinogen oxidase decreases expression EXP trovafloxacin results in decreased expression of CPOX mRNA CTD PMID:24136188 NCBI chr11:44,039,665...44,049,648
Ensembl chr11:44,039,669...44,049,648
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP trovafloxacin results in increased expression of CPT1A mRNA CTD PMID:24136188 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Crk CRK proto-oncogene, adaptor protein multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CRK mRNA CTD PMID:18930950 NCBI chr10:63,829,731...63,855,999
Ensembl chr10:63,829,807...63,852,780
JBrowse link
G Cs citrate synthase decreases expression EXP trovafloxacin results in decreased expression of CS mRNA CTD PMID:24136188 NCBI chr 7:2,752,680...2,778,963
Ensembl chr 7:2,752,680...2,778,963
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CXCL2 mRNA; trovafloxacin promotes the reaction [TNF protein results in increased expression of CXCL2 protein] CTD PMID:18930950, PMID:19638433 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CXCL3 mRNA; trovafloxacin promotes the reaction [TNF protein results in increased expression of CXCL1 protein] CTD PMID:18930950, PMID:19638433 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO trovafloxacin results in decreased activity of CYP19A1 protein CTD PMID:26141389 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp2b12 cytochrome P450, family 2, subfamily b, polypeptide 12 decreases expression EXP trovafloxacin results in decreased expression of CYP2B12 mRNA CTD PMID:24136188 NCBI chr 1:83,511,167...83,522,965
Ensembl chr 1:83,511,167...83,584,589
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CYP7A1 mRNA CTD PMID:18930950 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 increases expression EXP trovafloxacin results in increased expression of CYP8B1 mRNA CTD PMID:24136188 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G Dapk1 death associated protein kinase 1 decreases expression EXP trovafloxacin results in decreased expression of DAPK1 mRNA CTD PMID:24136188 NCBI chr17:4,297,038...4,454,941
Ensembl chr17:4,297,224...4,454,778
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases expression ISO trovafloxacin results in decreased expression of DDIT3 mRNA CTD PMID:24136188 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddx1 DEAD-box helicase 1 decreases expression EXP trovafloxacin results in decreased expression of DDX1 mRNA CTD PMID:24136188 NCBI chr 6:38,422,892...38,453,762
Ensembl chr 6:38,422,888...38,453,797
JBrowse link
G Ddx17 DEAD-box helicase 17 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of DDX17 mRNA CTD PMID:18930950 NCBI chr 7:120,761,843...120,765,012
Ensembl chr 7:120,761,826...120,780,641
JBrowse link
G Derl2 derlin 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of DERL2 mRNA CTD PMID:18930950 NCBI chr10:57,641,682...57,653,554
Ensembl chr10:57,644,207...57,653,359
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 decreases expression EXP trovafloxacin results in decreased expression of DGAT2 mRNA CTD PMID:24136188 NCBI chr 1:164,113,459...164,143,818
Ensembl chr 1:164,113,459...164,143,818
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase decreases expression EXP trovafloxacin results in decreased expression of DLST mRNA CTD PMID:24136188 NCBI chr 6:108,936,534...108,961,322
Ensembl chr 6:108,936,664...108,959,803
JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of DNAJB2 mRNA CTD PMID:18930950 NCBI chr 9:82,436,453...82,444,669
Ensembl chr 9:82,436,458...82,444,668
JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 decreases expression EXP trovafloxacin results in decreased expression of DNPH1 mRNA CTD PMID:24136188 NCBI chr 9:16,845,764...16,848,514
Ensembl chr 9:16,845,525...16,848,503
JBrowse link
G Dtymk deoxythymidylate kinase decreases expression EXP trovafloxacin results in decreased expression of DTYMK mRNA CTD PMID:24136188 NCBI chr 9:100,921,565...100,930,399
Ensembl chr 9:100,921,565...100,930,399
JBrowse link
G Dusp16 dual specificity phosphatase 16 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of DUSP16 mRNA CTD PMID:18930950 NCBI chr 4:168,470,141...168,551,346
Ensembl chr 4:168,472,412...168,517,177
JBrowse link
G Dusp8 dual specificity phosphatase 8 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of DUSP8 mRNA CTD PMID:18930950 NCBI chr 1:215,030,429...215,043,111
Ensembl chr 1:215,030,429...215,033,460
JBrowse link
G Dut deoxyuridine triphosphatase decreases expression EXP trovafloxacin results in decreased expression of DUT mRNA CTD PMID:24136188 NCBI chr 3:117,514,399...117,525,450
Ensembl chr 3:117,514,444...117,525,446
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of EGFR mRNA CTD PMID:18930950 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha decreases expression EXP trovafloxacin results in decreased expression of EIF2S1 mRNA CTD PMID:24136188 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of EIF2S2 mRNA CTD PMID:18930950 NCBI chr 3:150,391,455...150,412,179
Ensembl chr 3:150,391,460...150,412,179
JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of EIF3A mRNA CTD PMID:18930950 NCBI chr 1:282,139,809...282,170,017
Ensembl chr 1:282,139,823...282,170,017
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C decreases expression EXP trovafloxacin results in decreased expression of EIF3C mRNA CTD PMID:24136188 NCBI chr 1:197,964,406...197,982,917
Ensembl chr 1:197,964,407...197,982,601
JBrowse link
G Eif3l eukaryotic translation initiation factor 3, subunit L decreases expression EXP trovafloxacin results in decreased expression of EIF3L mRNA CTD PMID:24136188 NCBI chr 7:120,320,547...120,331,596
Ensembl chr 7:120,320,547...120,331,595
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 increases expression EXP trovafloxacin results in increased expression of EIF4A2 mRNA CTD PMID:24136188 NCBI chr11:81,373,047...81,379,680
Ensembl chr11:81,373,048...81,379,871
JBrowse link
G Eif6 eukaryotic translation initiation factor 6 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of EIF6 mRNA CTD PMID:18930950 NCBI chr 3:151,356,867...151,363,201
Ensembl chr 3:151,356,868...151,363,115
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 decreases expression EXP trovafloxacin results in decreased expression of ELOVL6 mRNA CTD PMID:24136188 NCBI chr 2:234,187,490...234,296,124
Ensembl chr 2:234,189,105...234,296,145
Ensembl chr 2:234,189,105...234,296,145
JBrowse link
G Emc1 ER membrane protein complex subunit 1 decreases expression EXP trovafloxacin results in decreased expression of EMC1 mRNA CTD PMID:24136188 NCBI chr 5:157,820,908...157,846,226
Ensembl chr 5:157,820,908...157,846,226
JBrowse link
G Ephx1 epoxide hydrolase 1 decreases expression EXP trovafloxacin results in decreased expression of EPHX1 mRNA CTD PMID:24136188 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Ergic1 endoplasmic reticulum-golgi intermediate compartment 1 decreases expression EXP trovafloxacin results in decreased expression of ERGIC1 mRNA CTD PMID:24136188 NCBI chr10:16,821,393...16,912,050
Ensembl chr10:16,821,880...16,910,641
JBrowse link
G Erp29 endoplasmic reticulum protein 29 decreases expression EXP trovafloxacin results in decreased expression of ERP29 mRNA CTD PMID:24136188 NCBI chr12:40,619,377...40,625,884
Ensembl chr12:40,619,377...40,625,883
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ERRFI1 mRNA CTD PMID:18930950 NCBI chr 5:167,951,564...167,966,011
Ensembl chr 5:167,952,728...167,966,009
JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ETS2 mRNA CTD PMID:18930950 NCBI chr11:36,075,709...36,092,495
Ensembl chr11:36,075,709...36,092,495
JBrowse link
G F2 coagulation factor II multiple interactions ISO [Lipopolysaccharides co-treated with trovafloxacin] results in increased activity of F2 protein CTD PMID:19367693 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G Fam98a family with sequence similarity 98, member A decreases expression EXP trovafloxacin results in decreased expression of FAM98A mRNA CTD PMID:24136188 NCBI chr 6:21,051,327...21,065,986
Ensembl chr 6:21,051,327...21,065,986
JBrowse link
G Fasn fatty acid synthase multiple interactions
decreases expression
ISO
EXP
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of FASN mRNA
trovafloxacin results in decreased expression of FASN mRNA
CTD PMID:18930950, PMID:24136188 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbxo9 f-box protein 9 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of FBXO9 mRNA CTD PMID:18930950 NCBI chr 8:85,388,331...85,413,896
Ensembl chr 8:85,388,333...85,413,484
JBrowse link
G Fga fibrinogen alpha chain multiple interactions ISO [Lipopolysaccharides co-treated with trovafloxacin] results in increased expression of FGA protein CTD PMID:19367693 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 decreases expression EXP trovafloxacin results in decreased expression of FKBP4 mRNA CTD PMID:24136188 NCBI chr 4:161,748,993...161,757,447
Ensembl chr 4:161,748,993...161,757,447
JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 increases expression EXP trovafloxacin results in increased expression of FMO3 mRNA CTD PMID:24136188 NCBI chr13:80,837,418...80,856,214
Ensembl chr13:80,837,420...80,862,963
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of FOS mRNA CTD PMID:18930950 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fzd7 frizzled class receptor 7 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of FZD7 mRNA CTD PMID:18930950 NCBI chr 9:66,305,731...66,308,550
Ensembl chr 9:66,305,731...66,308,550
JBrowse link
G G6pc glucose-6-phosphatase, catalytic subunit multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of G6PC mRNA CTD PMID:18930950 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases expression EXP trovafloxacin results in decreased expression of G6PD mRNA CTD PMID:24136188 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma decreases expression EXP trovafloxacin results in decreased expression of GADD45G mRNA CTD PMID:24136188 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase decreases expression EXP trovafloxacin results in decreased expression of GAPDH mRNA CTD PMID:24136188 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gcgr glucagon receptor multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of GCGR mRNA CTD PMID:18930950 NCBI chr10:109,707,863...109,716,253
Ensembl chr10:109,707,962...109,716,128
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression
multiple interactions
EXP
ISO
trovafloxacin results in decreased expression of GCLC mRNA
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of GCLC mRNA
CTD PMID:18930950, PMID:24136188 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gfm1 G elongation factor, mitochondrial 1 decreases expression EXP trovafloxacin results in decreased expression of GFM1 mRNA CTD PMID:24136188 NCBI chr 2:164,601,575...164,646,478
Ensembl chr 2:164,601,586...164,646,439
JBrowse link
G Ggcx gamma-glutamyl carboxylase decreases expression EXP trovafloxacin results in decreased expression of GGCX mRNA CTD PMID:24136188 NCBI chr 4:100,277,345...100,293,097
Ensembl chr 4:100,277,391...100,293,250
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GJA1 mRNA CTD PMID:18930950 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Glrx3 glutaredoxin 3 decreases expression EXP trovafloxacin results in decreased expression of GLRX3 mRNA CTD PMID:24136188 NCBI chr 1:209,768,696...209,799,912
Ensembl chr 1:209,768,696...209,799,903
JBrowse link
G Glyat glycine-N-acyltransferase increases expression EXP trovafloxacin results in increased expression of GLYAT mRNA CTD PMID:24136188 NCBI chr 1:229,060,125...229,081,113
Ensembl chr 1:229,063,714...229,080,410
JBrowse link
G Gnl3 G protein nucleolar 3 increases expression EXP trovafloxacin results in increased expression of GNL3 mRNA CTD PMID:24136188 NCBI chr16:7,097,580...7,103,518
Ensembl chr16:7,097,507...7,103,604
JBrowse link
G Gnpnat1 glucosamine-phosphate N-acetyltransferase 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of GNPNAT1 mRNA CTD PMID:18930950 NCBI chr15:19,721,292...19,734,032
Ensembl chr15:19,721,293...19,733,967
JBrowse link
G Golga2 golgin A2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of GOLGA2 mRNA CTD PMID:18930950 NCBI chr 3:11,317,328...11,337,569
Ensembl chr 3:11,317,183...11,336,458
JBrowse link
G Golga4 golgin A4 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of GOLGA4 mRNA CTD PMID:18930950 NCBI chr 8:127,171,221...127,248,938
Ensembl chr 8:127,171,537...127,248,538
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression EXP trovafloxacin results in decreased expression of GPAM mRNA CTD PMID:24136188 NCBI chr 1:275,843,823...275,906,880
Ensembl chr 1:275,846,819...275,906,686
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 increases expression EXP trovafloxacin results in increased expression of GPLD1 mRNA CTD PMID:24136188 NCBI chr17:42,085,027...42,131,344
Ensembl chr17:42,085,028...42,127,678
JBrowse link
G Gsr glutathione-disulfide reductase decreases expression EXP trovafloxacin results in decreased expression of GSR mRNA CTD PMID:24136188 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gss glutathione synthetase decreases expression EXP trovafloxacin results in decreased expression of GSS mRNA CTD PMID:24136188 NCBI chr 3:151,076,254...151,106,557
Ensembl chr 3:151,076,254...151,106,557
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 decreases expression EXP trovafloxacin results in decreased expression of GSTA3 mRNA CTD PMID:24136188 NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases phosphorylation
increases expression
ISO [TNF protein co-treated with trovafloxacin] results in increased expression of H2AX protein modified form; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[TNF protein co-treated with trovafloxacin] results in increased expression of H2AX protein modified form]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [trovafloxacin results in increased expression of H2AX protein modified form]; TNF protein promotes the reaction [trovafloxacin results in increased expression of H2AX protein modified form]
trovafloxacin results in increased phosphorylation of H2AX protein
CTD PMID:24817034, PMID:25748550 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 decreases expression EXP trovafloxacin results in decreased expression of HACD3 mRNA CTD PMID:24136188 NCBI chr 8:70,471,572...70,509,874
Ensembl chr 8:70,471,572...70,509,874
JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 increases expression EXP trovafloxacin results in increased expression of HACL1 mRNA CTD PMID:24136188 NCBI chr16:7,720,047...7,758,119
Ensembl chr16:7,714,465...7,758,189
JBrowse link
G Hao2 hydroxyacid oxidase 2 increases expression EXP trovafloxacin results in increased expression of HAO2 mRNA CTD PMID:24136188 NCBI chr 2:200,785,492...200,808,868
Ensembl chr 2:200,778,122...200,808,857
JBrowse link
G Hmgn3 high mobility group nucleosomal binding domain 3 decreases expression EXP trovafloxacin results in decreased expression of HMGN3 mRNA CTD PMID:24136188 NCBI chr 8:90,628,203...90,665,055
Ensembl chr 8:90,628,209...90,664,554
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of HMOX1 mRNA CTD PMID:18930950 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnrnpf heterogeneous nuclear ribonucleoprotein F multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of HNRNPF mRNA CTD PMID:18930950 NCBI chr 4:149,957,143...149,978,896
Ensembl chr 4:149,957,206...149,978,895
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 decreases expression EXP trovafloxacin results in decreased expression of HSPH1 mRNA CTD PMID:24136188 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 decreases expression EXP trovafloxacin results in decreased expression of HTATIP2 mRNA CTD PMID:24136188 NCBI chr 1:105,094,272...105,109,459
Ensembl chr 1:105,094,411...105,109,461
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
decreases expression
ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ICAM1 mRNA; trovafloxacin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]
[trovafloxacin co-treated with TNF protein] results in increased expression of ICAM1 mRNA
trovafloxacin results in decreased expression of ICAM1 mRNA
CTD PMID:18930950, PMID:32035082 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Id2 inhibitor of DNA binding 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of ID2 mRNA CTD PMID:18930950 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
JBrowse link
G Ide insulin degrading enzyme decreases expression EXP trovafloxacin results in decreased expression of IDE mRNA CTD PMID:24136188 NCBI chr 1:255,914,465...256,014,168
Ensembl chr 1:255,914,447...256,013,495
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 decreases expression EXP trovafloxacin results in decreased expression of IDH2 mRNA CTD PMID:24136188 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Ifng interferon gamma multiple interactions ISO
EXP
IFNG protein promotes the reaction [[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF protein]; IFNG protein results in increased susceptibility to [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5]; trovafloxacin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IFNG protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of IFNG protein]
[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to trovafloxacin
CTD PMID:18930950, PMID:19362101, PMID:19638433 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression
multiple interactions
EXP
ISO
trovafloxacin results in increased expression of IFRD1 mRNA
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IFRD1 mRNA
CTD PMID:18930950, PMID:24136188 NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IGFBP1 mRNA CTD PMID:18930950 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Il17ra interleukin 17 receptor A multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL17RA mRNA CTD PMID:18930950 NCBI chr 4:152,995,865...153,018,394
Ensembl chr 4:152,995,865...153,018,394
JBrowse link
G Il18 interleukin 18 multiple interactions ISO IL18 protein results in increased susceptibility to [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5]; trovafloxacin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL18 protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of IL18 protein] CTD PMID:18930950, PMID:19638433 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO
EXP
[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to trovafloxacin; [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to trovafloxacin CTD PMID:19362101 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [trovafloxacin results in increased activity of CASP3 protein]; [trovafloxacin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [trovafloxacin co-treated with IL1B protein] affects the localization of SELE protein; [trovafloxacin co-treated with IL1B protein] results in increased activity of CASP3 protein; [trovafloxacin co-treated with IL1B protein] results in increased expression of SELE mRNA; trovafloxacin promotes the reaction [IL1B protein results in increased secretion of SELE protein]
trovafloxacin promotes the reaction [TNF protein results in increased expression of IL1B protein]
CTD PMID:10822086, PMID:19638433, PMID:30876886 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to trovafloxacin; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [trovafloxacin results in increased activity of CASP3 protein]; [trovafloxacin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [trovafloxacin co-treated with IL6 protein] results in increased activity of CASP3 protein
trovafloxacin promotes the reaction [TNF protein results in increased expression of IL6 protein]
CTD PMID:19362101, PMID:19638433, PMID:30876886 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 increases expression EXP trovafloxacin results in increased expression of IP6K2 mRNA CTD PMID:24136188 NCBI chr 8:117,574,136...117,599,849
Ensembl chr 8:117,574,161...117,599,848
JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions
decreases expression
ISO
EXP
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IRF1 mRNA
trovafloxacin results in decreased expression of IRF1 mRNA
CTD PMID:18930950, PMID:24136188 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ISG20 mRNA CTD PMID:18930950 NCBI chr 1:140,602,553...140,608,892
Ensembl chr 1:140,601,791...140,608,946
JBrowse link
G Ist1 IST1 factor associated with ESCRT-III increases expression EXP trovafloxacin results in increased expression of IST1 mRNA CTD PMID:24136188 NCBI chr19:41,968,692...41,990,843
Ensembl chr19:41,968,705...41,990,843
JBrowse link
G Ivns1abp influenza virus NS1A binding protein multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IVNS1ABP mRNA CTD PMID:18930950 NCBI chr13:68,702,970...68,722,472
Ensembl chr13:68,702,820...68,722,472
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of JUNB mRNA CTD PMID:18930950 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Klf9 Kruppel-like factor 9 increases expression EXP trovafloxacin results in increased expression of KLF9 mRNA CTD PMID:24136188 NCBI chr 1:240,908,483...240,933,198
Ensembl chr 1:240,908,483...240,933,198
JBrowse link
G Klhl24 kelch-like family member 24 increases expression EXP trovafloxacin results in increased expression of KLHL24 mRNA CTD PMID:24136188 NCBI chr11:84,613,101...84,643,674
Ensembl chr11:84,615,760...84,633,504
JBrowse link
G Kpna2 karyopherin subunit alpha 2 decreases expression EXP trovafloxacin results in decreased expression of KPNA2 mRNA CTD PMID:24136188 NCBI chr10:95,200,029...95,212,111
Ensembl chr10:95,200,030...95,212,111
JBrowse link
G Kpnb1 karyopherin subunit beta 1 decreases expression EXP trovafloxacin results in decreased expression of KPNB1 mRNA CTD PMID:24136188 NCBI chr10:85,096,517...85,124,641
Ensembl chr10:85,093,841...85,124,644
JBrowse link
G Krt18 keratin 18 decreases expression EXP trovafloxacin results in decreased expression of KRT18 mRNA CTD PMID:24136188 NCBI chr 7:143,629,455...143,633,131
Ensembl chr 7:143,629,455...143,633,131
JBrowse link
G Laptm4b lysosomal protein transmembrane 4 beta decreases expression EXP trovafloxacin results in decreased expression of LAPTM4B mRNA CTD PMID:24136188 NCBI chr 7:72,924,911...72,968,099
Ensembl chr 7:72,924,799...72,968,101
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of LDLR mRNA CTD PMID:18930950 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Letm1 leucine zipper and EF-hand containing transmembrane protein 1 decreases expression EXP trovafloxacin results in decreased expression of LETM1 mRNA CTD PMID:24136188 NCBI chr14:82,227,790...82,267,298
Ensembl chr14:82,227,708...82,267,350
JBrowse link
G Lgalsl galectin-like decreases expression EXP trovafloxacin results in decreased expression of LGALSL mRNA CTD PMID:24136188 NCBI chr14:105,047,915...105,055,421
Ensembl chr14:105,047,919...105,055,421
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of LITAF mRNA CTD PMID:18930950 NCBI chr10:4,753,546...4,763,272
Ensembl chr10:4,719,713...4,763,510
JBrowse link
G Lmna lamin A/C decreases expression EXP trovafloxacin results in decreased expression of LMNA mRNA CTD PMID:24136188 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G LOC100364500 RT1 class I, locus CE11-like multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of HLA-A mRNA CTD PMID:18930950 NCBI chr20:2,704,153...2,707,111
Ensembl chr20:2,704,148...2,707,120
JBrowse link
G Lpin1 lipin 1 increases expression EXP trovafloxacin results in increased expression of LPIN1 mRNA CTD PMID:24136188 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
G Lrp6 LDL receptor related protein 6 increases expression EXP trovafloxacin results in increased expression of LRP6 mRNA CTD PMID:24136188 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
G Lsm4 LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression EXP trovafloxacin results in decreased expression of LSM4 mRNA CTD PMID:24136188 NCBI chr16:20,506,399...20,511,818
Ensembl chr16:20,506,399...20,511,818
JBrowse link
G Lta4h leukotriene A4 hydrolase decreases expression EXP trovafloxacin results in decreased expression of LTA4H mRNA CTD PMID:24136188 NCBI chr 7:34,288,333...34,320,243
Ensembl chr 7:34,288,365...34,320,235
JBrowse link
G Lyz2 lysozyme 2 decreases expression EXP trovafloxacin results in decreased expression of LYZ2 mRNA CTD PMID:24136188 NCBI chr 7:60,335,968...60,341,264
Ensembl chr 7:60,335,969...60,341,264
JBrowse link
G Mal2 mal, T-cell differentiation protein 2 decreases expression EXP trovafloxacin results in decreased expression of MAL2 mRNA CTD PMID:24136188 NCBI chr 7:94,130,852...94,163,649
Ensembl chr 7:94,130,852...94,163,645
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of MANF mRNA CTD PMID:18930950 NCBI chr 8:115,623,175...115,626,408
Ensembl chr 8:115,623,178...115,626,380
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of MAP2K7 mRNA CTD PMID:18930950 NCBI chr12:2,546,278...2,555,310
Ensembl chr12:2,548,218...2,555,164
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MAP3K8 mRNA CTD PMID:18930950 NCBI chr17:56,109,403...56,129,925
Ensembl chr17:56,109,549...56,129,919
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases activity
multiple interactions
ISO trovafloxacin results in increased activity of MAPK1 protein
[trovafloxacin co-treated with TNF protein] results in increased phosphorylation of MAPK1 protein
U 0126 inhibits the reaction [trovafloxacin results in increased activity of MAPK1 protein]
CTD PMID:24525298, PMID:32035082 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases activity
multiple interactions
ISO trovafloxacin results in increased activity of MAPK3 protein
[trovafloxacin co-treated with TNF protein] results in increased phosphorylation of MAPK3 protein
U 0126 inhibits the reaction [trovafloxacin results in increased activity of MAPK3 protein]
CTD PMID:24525298, PMID:32035082 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 multiple interactions
increases phosphorylation
ISO SB 203580 inhibits the reaction [trovafloxacin results in increased phosphorylation of MAPKAPK2 protein] CTD PMID:24525298 NCBI chr13:47,785,157...47,871,684
Ensembl chr13:47,785,161...47,831,110
JBrowse link
G Mavs mitochondrial antiviral signaling protein multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of MAVS mRNA CTD PMID:18930950 NCBI chr 3:123,776,147...123,790,572
Ensembl chr 3:123,776,181...123,790,567
JBrowse link
G Mdh2 malate dehydrogenase 2 decreases expression EXP trovafloxacin results in decreased expression of MDH2 mRNA CTD PMID:24136188 NCBI chr12:23,941,451...23,954,406
Ensembl chr12:23,941,448...23,954,431
JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MDM2 mRNA CTD PMID:18930950 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Me1 malic enzyme 1 decreases expression EXP trovafloxacin results in decreased expression of ME1 mRNA CTD PMID:24136188 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Med20 mediator complex subunit 20 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of MED20 mRNA CTD PMID:18930950 NCBI chr 9:15,379,379...15,393,131
Ensembl chr 9:15,379,385...15,393,131
JBrowse link
G Memo1 mediator of cell motility 1 decreases expression EXP trovafloxacin results in decreased expression of MEMO1 mRNA CTD PMID:24136188 NCBI chr 6:22,362,483...22,409,583
Ensembl chr 6:22,362,484...22,409,579
JBrowse link
G Mgll monoglyceride lipase decreases expression EXP trovafloxacin results in decreased expression of MGLL mRNA CTD PMID:24136188 NCBI chr 4:120,671,436...120,773,458
Ensembl chr 4:120,671,489...120,771,088
JBrowse link
G Mir877 microRNA 877 increases expression ISO trovafloxacin results in increased expression of MIR877 mRNA CTD PMID:27713024 NCBI chr20:3,318,872...3,318,956
Ensembl chr20:3,318,872...3,318,956
JBrowse link
G Mlxipl MLX interacting protein-like multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of MLXIPL mRNA CTD PMID:18930950 NCBI chr12:24,590,645...24,619,639 JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MMP13 mRNA CTD PMID:18930950 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mogs mannosyl-oligosaccharide glucosidase multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of MOGS mRNA CTD PMID:18930950 NCBI chr 4:113,948,328...113,951,731
Ensembl chr 4:113,948,514...113,951,847
JBrowse link
G Mphosph8 M-phase phosphoprotein 8 increases expression EXP trovafloxacin results in increased expression of MPHOSPH8 mRNA CTD PMID:24136188 NCBI chr15:36,918,843...36,946,712
Ensembl chr15:36,918,843...36,946,708
JBrowse link
G Mrpl12 mitochondrial ribosomal protein L12 decreases expression EXP trovafloxacin results in decreased expression of MRPL12 mRNA CTD PMID:24136188 NCBI chr10:109,658,032...109,662,535
Ensembl chr10:109,658,032...109,662,535
JBrowse link
G Mrps18b mitochondrial ribosomal protein S18B decreases expression EXP trovafloxacin results in decreased expression of MRPS18B mRNA CTD PMID:24136188 NCBI chr20:3,344,870...3,350,929
Ensembl chr20:3,344,870...3,350,927
JBrowse link
G Mt1 metallothionein 1 increases expression
multiple interactions
EXP
ISO
trovafloxacin results in increased expression of MT1A mRNA
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MT1E mRNA
CTD PMID:18930950, PMID:24136188 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mttp microsomal triglyceride transfer protein decreases expression EXP trovafloxacin results in decreased expression of MTTP mRNA CTD PMID:24136188 NCBI chr 2:243,366,181...243,407,608
Ensembl chr 2:243,366,181...243,407,608
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MYD88 mRNA CTD PMID:18930950 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Naa15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit decreases expression EXP trovafloxacin results in decreased expression of NAA15 mRNA CTD PMID:24136188 NCBI chr 2:140,471,437...140,534,259
Ensembl chr 2:140,471,690...140,534,259
JBrowse link
G Ndufaf4 NADH:ubiquinone oxidoreductase complex assembly factor 4 decreases expression EXP trovafloxacin results in decreased expression of NDUFAF4 mRNA CTD PMID:24136188 NCBI chr 5:39,251,370...39,256,542
Ensembl chr 5:39,251,337...39,257,512
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NEDD4L mRNA CTD PMID:18930950 NCBI chr18:60,392,376...60,719,720
Ensembl chr18:60,392,376...60,719,720
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NEDD9 mRNA CTD PMID:18930950 NCBI chr17:22,984,792...23,179,701
Ensembl chr17:22,984,844...23,179,701
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases expression
ISO [Lipopolysaccharides co-treated with trovafloxacin] results in increased expression of NFKBIA mRNA; [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NFKBIA mRNA; [trovafloxacin co-treated with TNF protein] results in decreased expression of NFKBIA protein; trovafloxacin promotes the reaction [TNF protein results in increased expression of NFKBIA mRNA]
[trovafloxacin co-treated with TNF protein] results in increased expression of NFKBIA mRNA
trovafloxacin results in increased expression of NFKBIA mRNA; trovafloxacin results in increased expression of NFKBIA protein
CTD PMID:18930950, PMID:32035082 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfkbiz NFKB inhibitor zeta multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NFKBIZ mRNA CTD PMID:18930950 NCBI chr11:47,243,342...47,271,487
Ensembl chr11:47,243,342...47,271,487
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 decreases expression EXP trovafloxacin results in decreased expression of NME1 mRNA CTD PMID:24136188 NCBI chr10:81,657,152...81,666,542
Ensembl chr10:81,657,153...81,666,523
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 decreases expression EXP trovafloxacin results in decreased expression of NME2 mRNA CTD PMID:24136188 NCBI chr10:81,648,216...81,653,717
Ensembl chr10:81,648,216...81,653,717
JBrowse link
G Noct nocturnin multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NOCT mRNA CTD PMID:18930950 NCBI chr 2:140,286,661...140,306,869
Ensembl chr 2:140,286,661...140,306,869
JBrowse link
G Notch2 notch receptor 2 decreases expression EXP trovafloxacin results in decreased expression of NOTCH2 mRNA CTD PMID:24136188 NCBI chr 2:200,187,184...200,320,403
Ensembl chr 2:200,187,179...200,320,215
JBrowse link
G Nr2f6 nuclear receptor subfamily 2, group F, member 6 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of NR2F6 mRNA CTD PMID:18930950 NCBI chr16:19,769,968...19,777,414
Ensembl chr16:19,769,968...19,777,414
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases expression EXP trovafloxacin results in increased expression of NR3C1 mRNA CTD PMID:24136188 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nudt7 nudix hydrolase 7 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of NUDT7 mRNA CTD PMID:18930950 NCBI chr19:46,455,745...46,470,070
Ensembl chr19:46,455,761...46,482,050
JBrowse link
G Nup98 nucleoporin 98 and 96 precursor increases expression EXP trovafloxacin results in increased expression of NUP98 mRNA CTD PMID:24136188 NCBI chr 1:167,213,866...167,308,851
Ensembl chr 1:167,213,866...167,308,851
JBrowse link
G Obp3 alpha-2u globulin PGCL4 increases expression EXP trovafloxacin results in increased expression of OBP3 mRNA CTD PMID:24136188 NCBI chr 5:77,313,357...77,316,875 JBrowse link
G P2ry2 purinergic receptor P2Y2 decreases expression EXP trovafloxacin results in decreased expression of P2RY2 mRNA CTD PMID:24136188 NCBI chr 1:166,031,228...166,045,423
Ensembl chr 1:166,031,272...166,037,424
JBrowse link
G Pacsin2 protein kinase C and casein kinase substrate in neurons 2 decreases expression EXP trovafloxacin results in decreased expression of PACSIN2 mRNA CTD PMID:24136188 NCBI chr 7:124,224,210...124,317,407
Ensembl chr 7:124,223,633...124,317,379
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 increases expression EXP trovafloxacin results in increased expression of PBLD1 mRNA CTD PMID:24136188 NCBI chr20:27,103,300...27,118,650
Ensembl chr20:27,103,317...27,117,663
JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 decreases expression EXP trovafloxacin results in decreased expression of PCSK6 mRNA CTD PMID:24136188 NCBI chr 1:126,749,508...126,947,392
Ensembl chr 1:126,749,508...126,947,392
JBrowse link
G Pctp phosphatidylcholine transfer protein decreases expression EXP trovafloxacin results in decreased expression of PCTP mRNA CTD PMID:24136188 NCBI chr10:77,491,445...77,537,268
Ensembl chr10:77,491,454...77,512,032
JBrowse link
G Pde4b phosphodiesterase 4B decreases expression
multiple interactions
EXP
ISO
trovafloxacin results in decreased expression of PDE4B mRNA
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PDE4B mRNA
CTD PMID:18930950, PMID:24136188 NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814
JBrowse link
G Pdhx pyruvate dehydrogenase complex, component X decreases expression EXP trovafloxacin results in decreased expression of PDHX mRNA CTD PMID:24136188 NCBI chr 3:92,910,300...92,933,725
Ensembl chr 3:92,909,725...92,969,050
JBrowse link
G Pdlim1 PDZ and LIM domain 1 decreases expression EXP trovafloxacin results in decreased expression of PDLIM1 mRNA CTD PMID:24136188 NCBI chr 1:259,308,326...259,357,006
Ensembl chr 1:259,308,296...259,357,056
JBrowse link
G Perp p53 apoptosis effector related to PMP22 decreases expression EXP trovafloxacin results in decreased expression of PERP mRNA CTD PMID:24136188 NCBI chr 1:14,224,392...14,236,838
Ensembl chr 1:14,224,393...14,236,846
JBrowse link
G Pex2 peroxisomal biogenesis factor 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of PEX2 mRNA CTD PMID:18930950 NCBI chr 2:98,251,756...98,269,185
Ensembl chr 2:98,252,925...98,269,184
JBrowse link
G Pgk1 phosphoglycerate kinase 1 decreases expression EXP trovafloxacin results in decreased expression of PGK1 mRNA CTD PMID:24136188 NCBI chr  X:77,263,399...77,279,373
Ensembl chr  X:77,263,359...77,279,367
JBrowse link
G Pgm1 phosphoglucomutase 1 decreases expression EXP trovafloxacin results in decreased expression of PGM1 mRNA CTD PMID:24136188 NCBI chr 5:118,743,632...118,803,055
Ensembl chr 5:118,743,632...118,803,055
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PHLDA1 mRNA CTD PMID:18930950 NCBI chr 7:54,247,460...54,249,664
Ensembl chr 7:54,247,460...54,249,664
JBrowse link
G Pink1 PTEN induced kinase 1 increases expression EXP trovafloxacin results in increased expression of PINK1 mRNA CTD PMID:24136188 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PIP5K1A mRNA CTD PMID:18930950 NCBI chr 2:196,227,669...196,270,949
Ensembl chr 2:196,227,670...196,270,826
JBrowse link
G Pisd phosphatidylserine decarboxylase multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of PISD mRNA CTD PMID:18930950 NCBI chr14:83,298,630...83,347,697
Ensembl chr14:83,298,674...83,346,738
JBrowse link
G Plbd1 phospholipase B domain containing 1 decreases expression EXP trovafloxacin results in decreased expression of PLBD1 mRNA CTD PMID:24136188 NCBI chr 4:170,564,387...170,620,681
Ensembl chr 4:170,564,367...170,620,703
JBrowse link
G Plin2 perilipin 2 decreases expression EXP trovafloxacin results in decreased expression of PLIN2 mRNA CTD PMID:24136188 NCBI chr 5:104,984,413...105,010,863
Ensembl chr 5:104,984,414...105,010,857
JBrowse link
G Plin3 perilipin 3 decreases expression EXP trovafloxacin results in decreased expression of PLIN3 mRNA CTD PMID:24136188 NCBI chr 9:10,769,739...10,781,659
Ensembl chr 9:10,773,901...10,781,109
JBrowse link
G Plk3 polo-like kinase 3 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PLK3 mRNA CTD PMID:18930950 NCBI chr 5:135,997,725...136,002,900
Ensembl chr 5:135,997,725...136,002,900
JBrowse link
G Plpp3 phospholipid phosphatase 3 increases expression EXP trovafloxacin results in increased expression of PLPP3 mRNA CTD PMID:24136188 NCBI chr 5:124,690,214...124,765,499
Ensembl chr 5:124,690,214...124,765,498
JBrowse link
G Pnp purine nucleoside phosphorylase multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PNP2 mRNA CTD PMID:18930950 NCBI chr15:27,875,883...27,883,566
Ensembl chr15:27,875,911...27,883,350
JBrowse link
G Polrmt RNA polymerase mitochondrial multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of POLRMT mRNA CTD PMID:18930950 NCBI chr 7:12,840,907...12,851,153
Ensembl chr 7:12,840,938...12,851,153
JBrowse link
G Ppa1 inorganic pyrophosphatase 1 decreases expression EXP trovafloxacin results in decreased expression of PPA1 mRNA CTD PMID:24136188 NCBI chr20:31,265,519...31,292,451
Ensembl chr20:31,265,483...31,310,674
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO trovafloxacin results in decreased expression of PPARA mRNA CTD PMID:25689681 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppox protoporphyrinogen oxidase decreases expression EXP trovafloxacin results in decreased expression of PPOX mRNA CTD PMID:24136188 NCBI chr13:89,650,094...89,654,998
Ensembl chr13:89,650,094...89,654,244
JBrowse link
G Ppp1r14a protein phosphatase 1, regulatory (inhibitor) subunit 14A decreases expression EXP trovafloxacin results in decreased expression of PPP1R14A mRNA CTD PMID:24136188 NCBI chr 1:87,224,683...87,232,842
Ensembl chr 1:87,224,677...87,232,848
JBrowse link
G Ppp1r14b protein phosphatase 1, regulatory (inhibitor) subunit 14B decreases expression EXP trovafloxacin results in decreased expression of PPP1R14B mRNA CTD PMID:24136188 NCBI chr 1:222,229,835...222,231,945
Ensembl chr 1:222,229,835...222,231,944
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PPP1R15A mRNA CTD PMID:18930950 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Preb prolactin regulatory element binding multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of PREB mRNA CTD PMID:18930950 NCBI chr 6:26,784,088...26,787,875
Ensembl chr 6:26,784,088...26,787,874
JBrowse link
G Proser2 proline and serine rich 2 increases expression EXP trovafloxacin results in increased expression of PROSER2 mRNA CTD PMID:24136188 NCBI chr17:76,079,641...76,140,428
Ensembl chr17:76,079,720...76,137,697
JBrowse link
G Prss23 serine protease 23 decreases expression EXP trovafloxacin results in decreased expression of PRSS23 mRNA CTD PMID:24136188 NCBI chr 1:153,732,528...153,742,111
Ensembl chr 1:153,732,532...153,752,541
JBrowse link
G Psma5 proteasome 20S subunit alpha 5 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PSMA5 mRNA CTD PMID:18930950 NCBI chr 2:211,050,344...211,073,706
Ensembl chr 2:211,050,360...211,073,714
JBrowse link
G Psmb10 proteasome 20S subunit beta 10 decreases expression EXP trovafloxacin results in decreased expression of PSMB10 mRNA CTD PMID:24136188 NCBI chr19:37,909,543...37,912,027
Ensembl chr19:37,909,546...37,912,027
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of PTEN mRNA CTD PMID:18930950 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptgr2 prostaglandin reductase 2 decreases expression EXP trovafloxacin results in decreased expression of PTGR2 mRNA CTD PMID:24136188 NCBI chr 6:107,999,832...108,031,645
Ensembl chr 6:107,999,846...108,031,643
JBrowse link
G Ptma prothymosin alpha decreases expression EXP trovafloxacin results in decreased expression of PTMA mRNA CTD PMID:24136188 NCBI chr 9:93,545,396...93,549,436
Ensembl chr 9:93,545,396...93,549,436
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 increases expression
multiple interactions
EXP
ISO
trovafloxacin results in increased expression of PTP4A1 mRNA
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PTP4A1 mRNA
CTD PMID:18930950, PMID:24136188 NCBI chr 9:37,223,363...37,254,222
Ensembl chr 9:37,223,729...37,231,291
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PTPN2 mRNA CTD PMID:18930950 NCBI chr18:63,415,298...63,489,240
Ensembl chr18:63,415,306...63,488,027
JBrowse link
G Ptpn21 protein tyrosine phosphatase, non-receptor type 21 decreases expression EXP trovafloxacin results in decreased expression of PTPN21 mRNA CTD PMID:24136188 NCBI chr 6:122,656,500...122,721,496
Ensembl chr 6:122,656,500...122,721,496
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin decreases expression EXP trovafloxacin results in decreased expression of PTTG1 mRNA CTD PMID:24136188 NCBI chr10:29,014,332...29,026,088
Ensembl chr10:29,020,049...29,026,002
JBrowse link
G Ran RAN, member RAS oncogene family decreases expression EXP trovafloxacin results in decreased expression of RAN mRNA CTD PMID:24136188 NCBI chr12:31,319,556...31,324,105
Ensembl chr12:31,320,624...31,323,810
JBrowse link
G Rangap1 RAN GTPase activating protein 1 decreases expression EXP trovafloxacin results in decreased expression of RANGAP1 mRNA CTD PMID:24136188 NCBI chr 7:122,939,266...122,967,178
Ensembl chr 7:122,940,376...122,967,178
JBrowse link
G Rarb retinoic acid receptor, beta decreases expression EXP trovafloxacin results in decreased expression of RARB mRNA CTD PMID:24136188 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression EXP trovafloxacin results in decreased expression of RB1 mRNA CTD PMID:24136188 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rcan1 regulator of calcineurin 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of RCAN1 mRNA CTD PMID:18930950 NCBI chr11:32,539,689...32,620,274
Ensembl chr11:32,539,683...32,550,539
JBrowse link
G Rdx radixin multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of RDX mRNA CTD PMID:18930950 NCBI chr 8:56,570,728...56,612,851
Ensembl chr 8:56,585,396...56,610,612
JBrowse link
G Reep6 receptor accessory protein 6 decreases expression EXP trovafloxacin results in decreased expression of REEP6 mRNA CTD PMID:24136188 NCBI chr 7:12,240,059...12,246,814
Ensembl chr 7:12,240,060...12,246,729
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of REL mRNA CTD PMID:18930950 NCBI chr14:108,490,794...108,517,582
Ensembl chr14:108,491,069...108,509,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
affects localization
ISO trovafloxacin affects the reaction [TNF protein affects the localization of RELA protein modified form]; trovafloxacin affects the reaction [TNF protein results in increased phosphorylation of RELA protein]
trovafloxacin affects the localization of RELA protein
trovafloxacin affects the reaction [Lipopolysaccharides affects the localization of RELA protein]
CTD PMID:32035082 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G RGD1308742 similar to Complement C5 precursor increases expression EXP trovafloxacin results in increased expression of RGD1308742 mRNA CTD PMID:24136188 NCBI chr 3:14,273,552...14,291,401
Ensembl chr 3:14,276,280...14,291,343
JBrowse link
G RGD1309534 similar to RIKEN cDNA 4931406C07 decreases expression EXP trovafloxacin results in decreased expression of RGD1309534 mRNA CTD PMID:24136188 NCBI chr 8:13,838,549...13,861,120
Ensembl chr 8:13,838,572...13,861,212
JBrowse link
G RGD1564804 similar to chromosome 1 open reading frame 50 increases expression EXP trovafloxacin results in increased expression of RGD1564804 mRNA CTD PMID:24136188 NCBI chr 5:138,274,907...138,279,285
Ensembl chr 5:138,274,907...138,279,285
JBrowse link
G Rmdn2 regulator of microtubule dynamics 2 decreases expression EXP trovafloxacin results in decreased expression of RMDN2 mRNA CTD PMID:24136188 NCBI chr 6:2,215,062...2,292,288
Ensembl chr 6:2,216,623...2,280,777
JBrowse link
G Rnd3 Rho family GTPase 3 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of RND3 mRNA CTD PMID:18930950 NCBI chr 3:36,643,374...36,660,727
Ensembl chr 3:36,642,587...36,660,758
JBrowse link
G Rnf26 ring finger protein 26 decreases expression EXP trovafloxacin results in decreased expression of RNF26 mRNA CTD PMID:24136188 NCBI chr 8:48,447,113...48,449,311
Ensembl chr 8:48,447,113...48,449,311
JBrowse link
G Rnf39 ring finger protein 39 increases expression EXP trovafloxacin results in increased expression of RNF39 mRNA CTD PMID:24136188 NCBI chr20:2,098,375...2,103,864
Ensembl chr20:2,098,375...2,103,864
JBrowse link
G Rnf6 ring finger protein 6 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of RNF6 mRNA CTD PMID:18930950 NCBI chr12:10,574,168...10,583,196
Ensembl chr12:10,574,168...10,583,208
JBrowse link
G Rpa1 replication protein A1 decreases expression EXP trovafloxacin results in decreased expression of RPA1 mRNA CTD PMID:24136188 NCBI chr10:62,140,419...62,191,518
Ensembl chr10:62,140,419...62,191,512
JBrowse link
G Rpl7l1 ribosomal protein L7-like 1 decreases expression EXP trovafloxacin results in decreased expression of RPL7L1 mRNA CTD PMID:24136188 NCBI chr 9:16,508,477...16,516,502
Ensembl chr 9:16,508,799...16,513,120
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 decreases expression EXP trovafloxacin results in decreased expression of RRM2 mRNA CTD PMID:24136188 NCBI chr 6:43,884,627...43,890,818
Ensembl chr 6:43,884,678...43,889,515
JBrowse link
G Rsrp1 arginine and serine rich protein 1 increases expression EXP trovafloxacin results in increased expression of RSRP1 mRNA CTD PMID:24136188 NCBI chr 5:153,260,930...153,264,669
Ensembl chr 5:153,260,930...153,264,669
JBrowse link
G S100a11 S100 calcium binding protein A11 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of S100A11 mRNA CTD PMID:18930950 NCBI chr 2:193,863,185...193,868,646
Ensembl chr 2:193,866,951...193,868,502
JBrowse link
G Sae1 SUMO1 activating enzyme subunit 1 decreases expression EXP trovafloxacin results in decreased expression of SAE1 mRNA CTD PMID:24136188 NCBI chr 1:78,277,524...78,333,281
Ensembl chr 1:78,277,515...78,333,321
JBrowse link
G Sarnp SAP domain containing ribonucleoprotein decreases expression EXP trovafloxacin results in decreased expression of SARNP mRNA CTD PMID:24136188 NCBI chr 7:3,246,220...3,300,467
Ensembl chr 7:3,246,220...3,300,455
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression EXP trovafloxacin results in increased expression of SAT1 mRNA CTD PMID:24136188 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP trovafloxacin results in decreased expression of SCD1 mRNA CTD PMID:24136188 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Sds serine dehydratase increases expression EXP trovafloxacin results in increased expression of SDS mRNA CTD PMID:24136188 NCBI chr12:41,620,429...41,627,741
Ensembl chr12:41,620,393...41,627,741
JBrowse link
G Sec24d SEC24 homolog D, COPII coat complex component decreases expression EXP trovafloxacin results in decreased expression of SEC24D mRNA CTD PMID:24136188 NCBI chr 2:227,455,704...227,562,801
Ensembl chr 2:227,455,722...227,562,319
JBrowse link
G Sele selectin E multiple interactions ISO [trovafloxacin co-treated with IL1B protein] affects the localization of SELE protein; [trovafloxacin co-treated with IL1B protein] results in increased expression of SELE mRNA; trovafloxacin promotes the reaction [IL1B protein results in increased secretion of SELE protein]
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SELE mRNA
CTD PMID:10822086, PMID:18930950 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Senp2 SUMO specific peptidase 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of SENP2 mRNA CTD PMID:18930950 NCBI chr11:82,627,973...82,664,702
Ensembl chr11:82,630,436...82,664,630
JBrowse link
G Serpina3m serpin family A member 3M multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SERPINA3 mRNA CTD PMID:18930950 NCBI chr 6:127,808,785...127,816,067
Ensembl chr 6:127,808,785...127,816,055
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SERPINE1 mRNA; SERPINE1 protein results in increased susceptibility to [trovafloxacin co-treated with Lipopolysaccharides]; trovafloxacin promotes the reaction [Lipopolysaccharides results in increased expression of SERPINE1 protein] CTD PMID:18930950, PMID:19367693 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sf3a3 splicing factor 3a, subunit 3 decreases expression EXP trovafloxacin results in decreased expression of SF3A3 mRNA CTD PMID:24136188 NCBI chr 5:142,702,721...142,722,350
Ensembl chr 5:142,702,685...142,722,341
JBrowse link
G Sfpq splicing factor proline and glutamine rich decreases expression EXP trovafloxacin results in decreased expression of SFPQ mRNA CTD PMID:24136188 NCBI chr 5:145,079,803...145,088,517
Ensembl chr 5:145,079,803...145,088,498
JBrowse link
G Sh3bp5 SH3-domain binding protein 5 increases expression EXP trovafloxacin results in increased expression of SH3BP5 mRNA CTD PMID:24136188 NCBI chr16:7,473,367...7,559,976
Ensembl chr16:7,473,370...7,538,201
JBrowse link
G Skil SKI-like proto-oncogene multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SKIL mRNA CTD PMID:18930950 NCBI chr 2:115,862,932...115,891,304
Ensembl chr 2:115,866,701...115,891,097
JBrowse link
G Slc11a2 solute carrier family 11 member 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SLC11A2 mRNA CTD PMID:18930950 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212
JBrowse link
G Slc17a2 solute carrier family 17, member 2 increases expression EXP trovafloxacin results in increased expression of SLC17A2 mRNA CTD PMID:24136188 NCBI chr17:43,567,528...43,584,228
Ensembl chr17:43,567,528...43,584,152
JBrowse link
G Slc17a3 solute carrier family 17 member 3 decreases expression
multiple interactions
EXP
ISO
trovafloxacin results in decreased expression of SLC17A3 mRNA
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of SLC17A3 mRNA
CTD PMID:18930950, PMID:24136188 NCBI chr17:43,518,760...43,545,160
Ensembl chr17:43,518,655...43,543,185
JBrowse link
G Slc22a1 solute carrier family 22 member 1 decreases expression EXP trovafloxacin results in decreased expression of SLC22A1 mRNA CTD PMID:24136188 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc34a2 solute carrier family 34 member 2 decreases expression EXP trovafloxacin results in decreased expression of SLC34A2 mRNA CTD PMID:24136188 NCBI chr14:60,257,211...60,276,516
Ensembl chr14:60,256,712...60,276,794
JBrowse link
G Slc35e3 solute carrier family 35, member E3 decreases expression EXP trovafloxacin results in decreased expression of SLC35E3 mRNA CTD PMID:24136188 NCBI chr 7:60,765,077...60,778,136
Ensembl chr 7:60,765,079...60,778,136
JBrowse link
G Slc39a14 solute carrier family 39 member 14 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SLC39A14 mRNA CTD PMID:18930950 NCBI chr15:51,982,872...52,029,841
Ensembl chr15:51,982,982...52,029,816
JBrowse link
G Slc41a2 solute carrier family 41 member 2 decreases expression EXP trovafloxacin results in decreased expression of SLC41A2 mRNA CTD PMID:24136188 NCBI chr 7:26,522,314...26,607,861
Ensembl chr 7:26,522,314...26,607,861
JBrowse link
G Slc46a1 solute carrier family 46 member 1 increases expression EXP trovafloxacin results in increased expression of SLC46A1 mRNA CTD PMID:24136188 NCBI chr10:65,728,508...65,741,708
Ensembl chr10:65,733,991...65,740,828
JBrowse link
G Slc7a2 solute carrier family 7 member 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SLC7A2 mRNA CTD PMID:18930950 NCBI chr16:54,459,409...54,513,349
Ensembl chr16:54,460,067...54,513,349
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SLC9A3R1 mRNA CTD PMID:18930950 NCBI chr10:103,713,045...103,730,145
Ensembl chr10:103,713,045...103,730,145
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 increases expression EXP trovafloxacin results in increased expression of SLCO1A2 mRNA CTD PMID:24136188 NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of SLCO1B3 mRNA CTD PMID:18930950 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
G Smarcd2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of SMARCD2 mRNA CTD PMID:18930950 NCBI chr10:94,451,866...94,460,732
Ensembl chr10:94,451,866...94,460,732
JBrowse link
G Smndc1 survival motor neuron domain containing 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SMNDC1 mRNA CTD PMID:18930950 NCBI chr 1:274,096,068...274,107,138
Ensembl chr 1:274,096,068...274,107,138
JBrowse link
G Snd1 staphylococcal nuclease and tudor domain containing 1 decreases expression EXP trovafloxacin results in decreased expression of SND1 mRNA CTD PMID:24136188 NCBI chr 4:55,772,377...56,171,669
Ensembl chr 4:55,772,377...56,171,668
JBrowse link
G Socs2 suppressor of cytokine signaling 2 increases expression
multiple interactions
EXP
ISO
trovafloxacin results in increased expression of SOCS2 mRNA
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SOCS2 mRNA
CTD PMID:18930950, PMID:24136188 NCBI chr 7:36,495,496...36,500,878
Ensembl chr 7:36,495,480...36,499,784
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SOCS3 mRNA CTD PMID:18930950 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SOD2 mRNA CTD PMID:18930950 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Spart spartin decreases expression EXP trovafloxacin results in decreased expression of SPG20 mRNA CTD PMID:24136188 NCBI chr 2:144,522,382...144,548,968
Ensembl chr 2:144,522,072...144,548,917
JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SPRED2 mRNA CTD PMID:18930950 NCBI chr14:104,268,362...104,290,206
Ensembl chr14:104,191,517...104,290,456
JBrowse link
G Sptssa serine palmitoyltransferase, small subunit A increases expression EXP trovafloxacin results in increased expression of SPTSSA mRNA CTD PMID:24136188 NCBI chr 6:75,540,132...75,551,545
Ensembl chr 6:75,540,174...75,551,625
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression EXP trovafloxacin results in decreased expression of SREBF1 mRNA CTD PMID:24136188 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Srm spermidine synthase decreases expression EXP trovafloxacin results in decreased expression of SRM mRNA CTD PMID:24136188 NCBI chr 5:165,405,168...165,408,325
Ensembl chr 5:165,405,168...165,408,320
JBrowse link
G Srp72 signal recognition particle 72 decreases expression EXP trovafloxacin results in decreased expression of SRP72 mRNA CTD PMID:24136188 NCBI chr14:33,447,583...33,453,788 JBrowse link
G Srrm2 serine/arginine repetitive matrix 2 increases expression EXP trovafloxacin results in increased expression of SRRM2 mRNA CTD PMID:24136188 NCBI chr10:13,128,820...13,162,956
Ensembl chr10:13,145,099...13,162,343
JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of SRSF1 mRNA CTD PMID:18930950 NCBI chr10:75,334,200...75,341,197
Ensembl chr10:75,335,146...75,341,197
JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 decreases expression
multiple interactions
EXP
ISO
trovafloxacin results in decreased expression of SRSF2 mRNA
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SRSF2 mRNA
CTD PMID:18930950, PMID:24136188 NCBI chr10:105,792,779...105,795,986
Ensembl chr10:105,792,779...105,795,958
JBrowse link
G Srsf3 serine and arginine rich splicing factor 3 decreases expression EXP trovafloxacin results in decreased expression of SRSF3 mRNA CTD PMID:24136188 NCBI chr20:6,288,285...6,298,218
Ensembl chr20:6,288,267...6,298,213
JBrowse link
G Srsf4 serine and arginine rich splicing factor 4 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SRSF4 mRNA CTD PMID:18930950 NCBI chr 5:150,032,999...150,060,769
Ensembl chr 5:150,032,999...150,060,765
JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of SRSF5 mRNA CTD PMID:18930950 NCBI chr 6:104,611,026...104,640,033
Ensembl chr 6:104,611,026...104,615,302
JBrowse link
G Ssx2ip SSX family member 2 interacting protein decreases expression EXP trovafloxacin results in decreased expression of SSX2IP mRNA CTD PMID:24136188 NCBI chr 2:252,263,323...252,296,049
Ensembl chr 2:252,263,386...252,296,051
JBrowse link
G Stag2 stromal antigen 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of STAG2 mRNA CTD PMID:18930950 NCBI chr  X:128,493,603...128,624,418
Ensembl chr  X:128,493,614...128,624,418
JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 increases expression EXP trovafloxacin results in increased expression of STARD4 mRNA CTD PMID:24136188 NCBI chr18:25,982,210...25,997,555
Ensembl chr18:25,984,638...25,997,555
JBrowse link
G Stard5 StAR-related lipid transfer domain containing 5 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of STARD5 mRNA CTD PMID:18930950 NCBI chr 1:145,770,135...145,780,001
Ensembl chr 1:145,770,135...145,780,001
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of STAT3 mRNA CTD PMID:18930950 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Stbd1 starch binding domain 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of STBD1 mRNA CTD PMID:18930950 NCBI chr14:16,976,355...16,979,760
Ensembl chr14:16,976,356...16,979,760
JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression EXP trovafloxacin results in decreased expression of STIP1 mRNA CTD PMID:24136188 NCBI chr 1:222,274,133...222,293,139
Ensembl chr 1:222,274,133...222,293,148
JBrowse link
G Stmn1 stathmin 1 decreases expression EXP trovafloxacin results in decreased expression of STMN1 mRNA CTD PMID:24136188 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806
JBrowse link
G Sts steroid sulfatase increases expression EXP trovafloxacin results in increased expression of STS mRNA CTD PMID:24136188 NCBI chr  X:45,420,418...45,428,748
Ensembl chr  X:45,420,596...45,428,750
JBrowse link
G Sumo2 small ubiquitin-like modifier 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of SUMO2 mRNA CTD PMID:18930950 NCBI chr10:104,085,401...104,097,983
Ensembl chr10:104,086,002...104,097,812
JBrowse link
G Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SYNCRIP mRNA CTD PMID:18930950 NCBI chr 8:96,100,692...96,266,342
Ensembl chr 8:96,105,025...96,266,342
JBrowse link
G Synrg synergin, gamma increases expression EXP trovafloxacin results in increased expression of SYNRG mRNA CTD PMID:24136188 NCBI chr10:71,278,698...71,357,791 JBrowse link
G Tat tyrosine aminotransferase multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TAT mRNA CTD PMID:18930950 NCBI chr19:41,675,639...41,686,195
Ensembl chr19:41,675,355...41,686,229
JBrowse link
G Tbc1d14 TBC1 domain family, member 14 increases expression EXP trovafloxacin results in increased expression of TBC1D14 mRNA CTD PMID:24136188 NCBI chr14:79,172,272...79,438,765
Ensembl chr14:79,205,466...79,438,764
JBrowse link
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 decreases expression EXP trovafloxacin results in decreased expression of TCIRG1 mRNA CTD PMID:24136188 NCBI chr 1:219,126,687...219,139,466
Ensembl chr 1:219,127,602...219,139,464
JBrowse link
G Tent2 terminal nucleotidyltransferase 2 decreases expression EXP trovafloxacin results in decreased expression of TENT2 mRNA CTD PMID:24136188 NCBI chr 2:22,746,290...22,798,252
Ensembl chr 2:22,747,547...22,798,214
JBrowse link
G Tfdp1 transcription factor Dp-1 decreases expression EXP trovafloxacin results in decreased expression of TFDP1 mRNA CTD PMID:24136188 NCBI chr16:81,088,642...81,127,244
Ensembl chr16:81,089,292...81,127,257
JBrowse link
G Tfg trafficking from ER to golgi regulator multiple interactions
decreases expression
ISO
EXP
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of TFG mRNA
trovafloxacin results in decreased expression of TFG mRNA
CTD PMID:18930950, PMID:24136188 NCBI chr11:46,180,189...46,206,723
Ensembl chr11:46,179,940...46,206,721
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TGIF1 mRNA CTD PMID:18930950 NCBI chr 9:119,181,079...119,190,698
Ensembl chr 9:119,181,083...119,190,698
JBrowse link
G Tgm2 transglutaminase 2 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TGM2 mRNA CTD PMID:18930950 NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257
JBrowse link
G Thbs1 thrombospondin 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of THBS1 mRNA CTD PMID:18930950 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Thrap3 thyroid hormone receptor associated protein 3 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of THRAP3 mRNA CTD PMID:18930950 NCBI chr 5:144,178,248...144,221,318
Ensembl chr 5:144,179,023...144,221,263
JBrowse link
G Thrsp thyroid hormone responsive decreases expression EXP trovafloxacin results in decreased expression of THRSP mRNA CTD PMID:24136188 NCBI chr 1:162,381,251...162,385,575
Ensembl chr 1:162,381,253...162,385,575
JBrowse link
G Tkfc triokinase and FMN cyclase decreases expression EXP trovafloxacin results in decreased expression of TKFC mRNA CTD PMID:24136188 NCBI chr 1:226,642,901...226,657,698
Ensembl chr 1:226,644,200...226,657,408
JBrowse link
G Tkt transketolase decreases expression EXP trovafloxacin results in decreased expression of TKT mRNA CTD PMID:24136188 NCBI chr16:6,609,670...6,634,608
Ensembl chr16:6,609,668...6,634,595
JBrowse link
G Tle1 TLE family member 1, transcriptional corepressor increases expression EXP trovafloxacin results in increased expression of TLE1 mRNA CTD PMID:24136188 NCBI chr 5:88,546,607...88,630,277
Ensembl chr 5:88,546,568...88,629,491
JBrowse link
G Tmem106b transmembrane protein 106B increases expression EXP trovafloxacin results in increased expression of TMEM106B mRNA CTD PMID:24136188 NCBI chr 4:39,517,679...39,534,491
Ensembl chr 4:39,517,548...39,535,169
JBrowse link
G Tmem41a transmembrane protein 41a decreases expression EXP trovafloxacin results in decreased expression of TMEM41A mRNA CTD PMID:24136188 NCBI chr11:82,734,525...82,741,177
Ensembl chr11:82,734,613...82,741,428
JBrowse link
G Tmpo thymopoietin decreases expression EXP trovafloxacin results in decreased expression of TMPO mRNA CTD PMID:24136188 NCBI chr 7:31,847,412...31,872,416
Ensembl chr 7:31,847,410...31,872,423
JBrowse link
G Tmx2 thioredoxin-related transmembrane protein 2 decreases expression EXP trovafloxacin results in decreased expression of TMX2 mRNA CTD PMID:24136188 NCBI chr 3:72,073,429...72,081,079
Ensembl chr 3:72,073,431...72,081,079
JBrowse link
G Tmx4 thioredoxin-related transmembrane protein 4 increases expression EXP trovafloxacin results in increased expression of TMX4 mRNA CTD PMID:24136188 NCBI chr 3:127,528,427...127,569,093
Ensembl chr 3:127,528,434...127,569,093
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases uptake
decreases expression
increases expression
increases response to substance
increases secretion
ISO
EXP
4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [[trovafloxacin co-treated with TNF protein] results in increased phosphorylation of ATR protein]; [IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to trovafloxacin; [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to trovafloxacin; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [trovafloxacin results in increased activity of CASP3 protein]; [TNF protein co-treated with trovafloxacin] results in increased activity of CASP3 protein; [TNF protein co-treated with trovafloxacin] results in increased expression of H2AX protein modified form; [trovafloxacin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [trovafloxacin co-treated with TNF protein] results in decreased expression of BIRC2 mRNA; [trovafloxacin co-treated with TNF protein] results in decreased expression of XIAP mRNA; [trovafloxacin co-treated with TNF protein] results in increased activity of CASP3 protein; [trovafloxacin co-treated with TNF protein] results in increased activity of CASP8 protein; [trovafloxacin co-treated with TNF protein] results in increased activity of CASP9 protein; [trovafloxacin co-treated with TNF protein] results in increased expression of BIRC3 mRNA; [trovafloxacin co-treated with TNF protein] results in increased expression of ICAM1 mRNA; [trovafloxacin co-treated with TNF protein] results in increased expression of NFKBIA mRNA; [trovafloxacin co-treated with TNF protein] results in increased expression of TNFAIP3 mRNA; [trovafloxacin co-treated with TNF protein] results in increased expression of TNFAIP3 protein; [trovafloxacin co-treated with TNF protein] results in increased phosphorylation of and results in increased activity of ATR protein; [trovafloxacin co-treated with TNF protein] results in increased phosphorylation of MAPK1 protein; [trovafloxacin co-treated with TNF protein] results in increased phosphorylation of MAPK3 protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[TNF protein co-treated with trovafloxacin] results in increased expression of H2AX protein modified form]; TNF protein promotes the reaction [trovafloxacin results in increased expression of H2AX protein modified form]; trovafloxacin affects the reaction [TNF protein affects the localization of RELA protein modified form]; trovafloxacin affects the reaction [TNF protein results in increased phosphorylation of RELA protein]; U 0126 inhibits the reaction [[TNF protein co-treated with trovafloxacin] results in increased activity of CASP3 protein]
trovafloxacin results in decreased uptake of TNF protein
trovafloxacin results in decreased expression of TNF
trovafloxacin results in increased expression of TNF mRNA; trovafloxacin results in increased expression of TNF protein
trovafloxacin results in increased susceptibility to TNF protein
trovafloxacin results in increased secretion of TNF protein
4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [trovafloxacin promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [trovafloxacin results in increased expression of and results in increased stability of TNF mRNA]; 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [trovafloxacin results in increased expression of TNF protein]; [Lipopolysaccharides co-treated with trovafloxacin] results in increased expression of TNF mRNA; [Pentoxifylline results in decreased expression of TNF mRNA] results in decreased susceptibility to [lipopolysaccharide, E coli O55-B5 co-treated with trovafloxacin]; [TNF protein co-treated with trovafloxacin] results in increased cleavage of CASP3 protein; [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF protein; [trovafloxacin co-treated with TNF protein] results in decreased expression of NFKBIA protein; IFNG protein promotes the reaction [[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF protein]; pyrazolanthrone inhibits the reaction [trovafloxacin promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; pyrazolanthrone inhibits the reaction [trovafloxacin results in increased expression of TNF mRNA]; TNF protein affects the susceptibility to [lipopolysaccharide, E coli O55-B5 co-treated with trovafloxacin]; TNF protein results in increased susceptibility to [Lipopolysaccharides co-treated with trovafloxacin]; trovafloxacin inhibits the reaction [TNF protein results in increased expression of BIRC2 mRNA]; trovafloxacin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; trovafloxacin promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]; trovafloxacin promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of CCL2 protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of CXCL1 protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of CXCL2 protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of IFNG protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of IL18 protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of IL1B protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of IL6 protein]; trovafloxacin promotes the reaction [TNF protein results in increased expression of NFKBIA mRNA]; trovafloxacin promotes the reaction [TNF protein results in increased expression of TNFAIP3 mRNA]; trovafloxacin results in increased expression of and results in increased stability of TNF mRNA; U 0126 inhibits the reaction [trovafloxacin promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; U 0126 inhibits the reaction [trovafloxacin results in increased expression of TNF mRNA]
TNF protein results in increased susceptibility to trovafloxacin
CTD PMID:17709330, PMID:18930950, PMID:19362101, PMID:19638433, PMID:24097668, PMID:24136188, PMID:24525298, PMID:24817034, PMID:25748550, PMID:30876886, PMID:32035082 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 multiple interactions
increases expression
ISO [Lipopolysaccharides co-treated with trovafloxacin] results in increased expression of TNFAIP3 mRNA; [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNFAIP3 mRNA; trovafloxacin promotes the reaction [TNF protein results in increased expression of TNFAIP3 mRNA]
[trovafloxacin co-treated with TNF protein] results in increased expression of TNFAIP3 mRNA; [trovafloxacin co-treated with TNF protein] results in increased expression of TNFAIP3 protein
trovafloxacin results in increased expression of TNFAIP3 mRNA
trovafloxacin results in increased expression of TNFAIP3 mRNA; trovafloxacin results in increased expression of TNFAIP3 protein
CTD PMID:18930950, PMID:32035082 NCBI chr 1:14,401,103...14,416,369
Ensembl chr 1:14,402,913...14,412,807
JBrowse link
G Tob2 transducer of ERBB2, 2 increases expression EXP trovafloxacin results in increased expression of TOB2 mRNA CTD PMID:24136188 NCBI chr 7:123,079,520...123,088,240
Ensembl chr 7:123,079,537...123,088,279
JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 decreases expression EXP trovafloxacin results in decreased expression of TOMM70A mRNA CTD PMID:24136188 NCBI chr11:45,477,053...45,511,409
Ensembl chr11:45,480,250...45,510,961
JBrowse link
G Top2a DNA topoisomerase II alpha decreases activity ISO trovafloxacin results in decreased activity of TOP2A protein CTD PMID:24817034 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Tpi1 triosephosphate isomerase 1 decreases expression EXP trovafloxacin results in decreased expression of TPI1 mRNA CTD PMID:24136188 NCBI chr 4:157,328,375...157,331,905
Ensembl chr 4:157,328,379...157,331,905
JBrowse link
G Tpm3 tropomyosin 3 decreases expression EXP trovafloxacin results in decreased expression of TPM3 mRNA CTD PMID:24136188 NCBI chr 2:189,423,534...189,451,340
Ensembl chr 2:189,423,559...189,451,029
JBrowse link
G Tpst1 tyrosylprotein sulfotransferase 1 increases expression EXP trovafloxacin results in increased expression of TPST1 mRNA CTD PMID:24136188 NCBI chr12:30,045,753...30,112,377
Ensembl chr12:30,045,751...30,106,893
JBrowse link
G Trak1 trafficking kinesin protein 1 increases expression EXP trovafloxacin results in increased expression of TRAK1 mRNA CTD PMID:24136188 NCBI chr 8:129,946,596...130,106,382
Ensembl chr 8:130,009,573...130,106,382
JBrowse link
G Ttc7a tetratricopeptide repeat domain 7A decreases expression EXP trovafloxacin results in decreased expression of TTC7A mRNA CTD PMID:24136188 NCBI chr 6:10,912,383...11,014,279
Ensembl chr 6:10,912,383...11,014,278
JBrowse link
G Tuba1c tubulin, alpha 1C decreases expression EXP trovafloxacin results in decreased expression of TUBA1C mRNA CTD PMID:24136188 NCBI chr 7:140,716,113...140,723,717
Ensembl chr 7:140,716,113...140,723,714
JBrowse link
G Tuba4a tubulin, alpha 4A decreases expression EXP trovafloxacin results in decreased expression of TUBA4A mRNA CTD PMID:24136188 NCBI chr 9:82,415,599...82,419,918
Ensembl chr 9:82,415,605...82,419,288
JBrowse link
G Tubb2a tubulin, beta 2A class IIa decreases expression EXP trovafloxacin results in decreased expression of TUBB2A mRNA CTD PMID:24136188 NCBI chr17:31,493,145...31,496,827
Ensembl chr17:31,493,107...31,498,651
JBrowse link
G Tubb4b tubulin, beta 4B class IVb multiple interactions
decreases expression
ISO
EXP
[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of TUBB4B mRNA
trovafloxacin results in decreased expression of TUBB4B mRNA
CTD PMID:18930950, PMID:24136188 NCBI chr 3:2,441,585...2,444,369
Ensembl chr 3:2,441,733...2,444,281
JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression EXP trovafloxacin results in decreased expression of TUBB5 mRNA CTD PMID:24136188 NCBI chr20:3,422,448...3,426,420
Ensembl chr20:3,422,461...3,426,371
JBrowse link
G Txlng taxilin gamma multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of TXLNG mRNA CTD PMID:18930950 NCBI chr  X:33,599,643...33,648,525
Ensembl chr  X:33,599,671...33,646,444
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C decreases expression EXP trovafloxacin results in decreased expression of UBE2C mRNA CTD PMID:24136188 NCBI chr 3:161,236,971...161,239,371
Ensembl chr 3:161,236,898...161,241,159
JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of UBE2I mRNA CTD PMID:18930950 NCBI chr10:14,618,615...14,639,274
Ensembl chr10:14,620,531...14,630,151
JBrowse link
G Ubqln1 ubiquilin 1 decreases expression EXP trovafloxacin results in decreased expression of UBQLN1 mRNA CTD PMID:24136188 NCBI chr17:6,840,441...6,878,842
Ensembl chr17:6,840,463...6,878,844
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 decreases expression EXP trovafloxacin results in decreased expression of UGT2B17 mRNA CTD PMID:24136188 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 increases expression EXP trovafloxacin results in increased expression of ULK1 mRNA CTD PMID:24136188 NCBI chr12:51,908,105...51,934,704
Ensembl chr12:51,908,448...51,934,702
JBrowse link
G Umps uridine monophosphate synthetase decreases expression EXP trovafloxacin results in decreased expression of UMPS mRNA CTD PMID:24136188 NCBI chr11:70,034,181...70,044,590
Ensembl chr11:70,034,139...70,044,628
JBrowse link
G Upp1 uridine phosphorylase 1 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of UPP1 mRNA CTD PMID:18930950 NCBI chr14:89,314,234...89,334,060
Ensembl chr14:89,314,176...89,334,276
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of VEGFA mRNA CTD PMID:18930950 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Wbp1l WW domain binding protein 1-like increases expression EXP trovafloxacin results in increased expression of WBP1L mRNA CTD PMID:24136188 NCBI chr 1:266,358,728...266,415,296
Ensembl chr 1:266,358,728...266,415,296
JBrowse link
G Xbp1 X-box binding protein 1 increases expression EXP trovafloxacin results in increased expression of XBP1 mRNA CTD PMID:24136188 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of XDH mRNA CTD PMID:18930950 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
G Xiap X-linked inhibitor of apoptosis multiple interactions
decreases expression
ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of XIAP mRNA
[trovafloxacin co-treated with TNF protein] results in decreased expression of XIAP mRNA
trovafloxacin results in decreased expression of XIAP mRNA
CTD PMID:18930950, PMID:32035082 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link
G Xpnpep2 X-prolyl aminopeptidase 2 decreases expression EXP trovafloxacin results in decreased expression of XPNPEP2 mRNA CTD PMID:24136188 NCBI chr  X:134,940,656...134,969,874
Ensembl chr  X:134,940,615...134,969,996
JBrowse link
G Xpo1 exportin 1 decreases expression EXP trovafloxacin results in decreased expression of XPO1 mRNA CTD PMID:24136188 NCBI chr14:108,007,421...108,049,088
Ensembl chr14:108,007,724...108,049,660
JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 decreases expression EXP trovafloxacin results in decreased expression of YARS1 mRNA CTD PMID:24136188 NCBI chr 5:147,375,350...147,403,578
Ensembl chr 5:147,375,350...147,403,571
JBrowse link
G Ypel3 yippee-like 3 increases expression EXP trovafloxacin results in increased expression of YPEL3 mRNA CTD PMID:24136188 NCBI chr 1:198,210,525...198,213,821
Ensembl chr 1:198,210,525...198,213,816
JBrowse link
G Ypel5 yippee-like 5 increases expression EXP trovafloxacin results in increased expression of YPEL5 mRNA CTD PMID:24136188 NCBI chr 6:24,069,351...24,084,758
Ensembl chr 6:24,064,738...24,084,757
JBrowse link
G Zfand5 zinc finger AN1-type containing 5 multiple interactions ISO [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of ZFAND5 mRNA CTD PMID:18930950 NCBI chr 1:238,842,506...238,854,030
Ensembl chr 1:238,843,338...238,852,566
JBrowse link
XL147 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of A2M mRNA CTD PMID:27935865 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Abca8 ATP binding cassette subfamily A member 8 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ABCA8B mRNA CTD PMID:27935865 NCBI chr10:98,236,919...98,308,288
Ensembl chr10:98,237,141...98,294,522
JBrowse link
G Abhd14b abhydrolase domain containing 14b multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of ABHD14B mRNA] CTD PMID:29891994 NCBI chr 8:115,149,638...115,154,556
Ensembl chr 8:115,150,514...115,154,550
JBrowse link
G Acod1 aconitate decarboxylase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of ACOD1 mRNA CTD PMID:27935865 NCBI chr15:93,612,968...93,622,322
Ensembl chr15:93,612,971...93,622,358
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of ACTA2 mRNA] CTD PMID:29891994 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Actg2 actin gamma 2, smooth muscle multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ACTG2 mRNA CTD PMID:27935865 NCBI chr 4:115,215,160...115,239,746
Ensembl chr 4:115,215,060...115,239,723
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of ADAM8 mRNA CTD PMID:27935865 NCBI chr 1:212,317,510...212,332,895
Ensembl chr 1:212,317,848...212,330,349
JBrowse link
G Adcy5 adenylate cyclase 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ADCY5 mRNA CTD PMID:27935865 NCBI chr11:68,695,839...68,842,452
Ensembl chr11:68,695,839...68,842,320
JBrowse link
G Adcyap1r1 ADCYAP receptor type I multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ADCYAP1R1 mRNA CTD PMID:27935865 NCBI chr 4:85,662,809...85,711,696
Ensembl chr 4:85,662,892...85,711,696
JBrowse link
G Adgra2 adhesion G protein-coupled receptor A2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ADGRA2 mRNA CTD PMID:27935865 NCBI chr16:69,094,587...69,133,015
Ensembl chr16:69,095,936...69,132,584
JBrowse link
G Adgrg3 adhesion G protein-coupled receptor G3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of ADGRG3 mRNA CTD PMID:27935865 NCBI chr19:10,392,001...10,422,606
Ensembl chr19:10,392,004...10,421,010
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ADIPOQ mRNA CTD PMID:27935865 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adora1 adenosine A1 receptor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ADORA1 mRNA CTD PMID:27935865 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Agbl1 ATP/GTP binding protein-like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of AGBL1 mRNA CTD PMID:27935865 NCBI chr 1:137,798,862...138,711,126
Ensembl chr 1:137,799,185...138,711,126
JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of AGTR2 mRNA CTD PMID:27935865 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of AKR1D1 mRNA CTD PMID:27935865 NCBI chr 4:65,110,706...65,143,930
Ensembl chr 4:65,110,746...65,143,941
JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of AMBP mRNA CTD PMID:27935865 NCBI chr 5:78,975,690...78,986,021
Ensembl chr 5:78,975,678...78,985,990
JBrowse link
G Anos1 anosmin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of WFDC17 mRNA CTD PMID:27935865 Ensembl chr10:70,999,780...71,000,627 JBrowse link
G Aoc3 amine oxidase, copper containing 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of AOC3 mRNA CTD PMID:27935865 NCBI chr10:89,251,370...89,259,313
Ensembl chr10:89,251,370...89,259,313
JBrowse link
G Apoc2 apolipoprotein C2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of APOC2 mRNA CTD PMID:27935865 NCBI chr 1:80,589,023...80,593,991
Ensembl chr 1:80,589,023...80,594,136
JBrowse link
G Apol9a apolipoprotein L 9a multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of APOL6 mRNA CTD PMID:27935865 NCBI chr 7:118,927,013...118,933,778
Ensembl chr 7:118,927,008...118,933,812
JBrowse link
G Arhgap36 Rho GTPase activating protein 36 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ARHGAP36 mRNA CTD PMID:27935865 NCBI chr  X:136,460,227...136,495,646
Ensembl chr  X:136,460,215...136,495,646
JBrowse link
G Arhgef19 Rho guanine nucleotide exchange factor 19 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of ARHGEF19 mRNA] CTD PMID:29891994 NCBI chr 5:159,754,954...159,773,699
Ensembl chr 5:159,755,535...159,773,699
JBrowse link
G Armcx6 armadillo repeat containing, X-linked 6 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of ARMCX6 mRNA] CTD PMID:29891994 NCBI chr  X:105,565,733...105,573,387
Ensembl chr  X:105,565,747...105,568,343
JBrowse link
G Asb10 ankyrin repeat and SOCS box-containing 10 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ASB10 mRNA CTD PMID:27935865 NCBI chr 4:7,158,293...7,167,505
Ensembl chr 4:7,158,448...7,167,509
JBrowse link
G Asb13 ankyrin repeat and SOCS box-containing 13 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of ASB13 mRNA] CTD PMID:29891994 NCBI chr17:70,215,401...70,234,103
Ensembl chr17:70,215,401...70,234,103
JBrowse link
G Asb16 ankyrin repeat and SOCS box-containing 16 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ASB16 mRNA CTD PMID:27935865 NCBI chr10:90,217,979...90,224,984
Ensembl chr10:90,217,924...90,226,537
JBrowse link
G Ascl2 achaete-scute family bHLH transcription factor 2 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of ASCL2 mRNA] CTD PMID:29891994 NCBI chr 1:216,154,002...216,156,409
Ensembl chr 1:216,154,002...216,156,409
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of ATP1A2 mRNA CTD PMID:27935865 NCBI chr13:90,651,682...90,676,629
Ensembl chr13:90,651,686...90,676,629
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of ATP1A3 mRNA CTD PMID:27935865 NCBI chr 1:81,852,423...81,881,565
Ensembl chr 1:81,852,429...81,881,549
JBrowse link
G Avpr1a arginine vasopressin receptor 1A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of AVPR1A mRNA CTD PMID:27935865 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G B4galnt2 beta-1,4-N-acetyl-galactosaminyl transferase 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of B4GALNT2 mRNA CTD PMID:27935865 NCBI chr10:83,677,768...83,701,487 JBrowse link
G Bend4 BEN domain containing 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of BEND4 mRNA CTD PMID:27935865 NCBI chr14:42,399,359...42,401,643
NCBI chr14:42,401,665...42,437,957
Ensembl chr14:42,401,706...42,431,480
JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of BHLHA15 mRNA CTD PMID:27935865 NCBI chr12:12,403,385...12,409,103
Ensembl chr12:12,403,385...12,407,561
JBrowse link
G Bpifa5 BPI fold containing family A, member 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of BPIFA5 mRNA CTD PMID:27935865 NCBI chr 3:149,643,481...149,649,398
Ensembl chr 3:149,643,481...149,649,398
JBrowse link
G Bpifb1 BPI fold containing family B, member 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of BPIFB1 mRNA CTD PMID:27935865 NCBI chr 3:149,668,099...149,702,399
Ensembl chr 3:149,668,102...149,702,399
JBrowse link
G Bricd5 BRICHOS domain containing 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of BRICD5 mRNA CTD PMID:27935865 NCBI chr10:13,839,599...13,841,132
Ensembl chr10:13,839,956...13,841,018
JBrowse link
G Btn1a1 butyrophilin, subfamily 1, member A1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of BTN1A1 mRNA CTD PMID:27935865 NCBI chr17:43,899,155...43,909,042
Ensembl chr17:43,900,450...43,909,627
JBrowse link
G C1qtnf2 C1q and TNF related 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of C1QTNF2 mRNA CTD PMID:27935865 NCBI chr10:29,067,102...29,084,035
Ensembl chr10:29,067,102...29,084,035
JBrowse link
G C1qtnf7 C1q and TNF related 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of C1QTNF7 mRNA CTD PMID:27935865 NCBI chr14:72,011,518...72,122,257
Ensembl chr14:72,011,461...72,122,158
JBrowse link
G C5ar1 complement C5a receptor 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of C5AR1 mRNA CTD PMID:27935865 NCBI chr 1:78,186,777...78,195,132
Ensembl chr 1:78,186,776...78,195,328
JBrowse link
G C5ar2 complement component 5a receptor 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of C5AR2 mRNA CTD PMID:27935865 NCBI chr 1:78,165,155...78,183,426
Ensembl chr 1:78,166,810...78,180,216
JBrowse link
G Ca3 carbonic anhydrase 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CAR3 mRNA CTD PMID:27935865 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of CAMK2N1 mRNA] CTD PMID:29891994 NCBI chr 5:156,876,706...156,878,486
Ensembl chr 5:156,876,706...156,878,486
JBrowse link
G Card10 caspase recruitment domain family, member 10 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of CARD10 mRNA] CTD PMID:29891994 NCBI chr 7:119,998,639...120,028,632
Ensembl chr 7:119,999,472...120,027,026
JBrowse link
G Cbx4 chromobox 4 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of CBX4 mRNA] CTD PMID:29891994 NCBI chr10:108,190,947...108,196,455
Ensembl chr10:108,190,995...108,196,217
JBrowse link
G Ccdc42 coiled-coil domain containing 42 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CCDC42 mRNA CTD PMID:27935865 NCBI chr10:55,169,312...55,179,489
Ensembl chr10:55,169,282...55,181,416
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CCL2 mRNA CTD PMID:27935865 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CCL3 mRNA CTD PMID:27935865 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CCL7 mRNA CTD PMID:27935865 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccna1 cyclin A1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CCNA1 mRNA; XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of CCNA1 mRNA] CTD PMID:27935865, PMID:29891994 NCBI chr 2:144,456,689...144,503,570
Ensembl chr 2:144,458,153...144,467,912
JBrowse link
G Ccno cyclin O multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CCNO mRNA CTD PMID:27935865 NCBI chr 2:44,857,043...44,860,317
Ensembl chr 2:44,857,213...44,860,315
JBrowse link
G Cd177 CD177 molecule multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CD177 mRNA CTD PMID:27935865 NCBI chr 1:82,964,683...82,987,306
Ensembl chr 1:82,964,683...82,987,253
JBrowse link
G Cd5l Cd5 molecule-like multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CD5L mRNA CTD PMID:27935865 NCBI chr 2:186,685,104...186,696,117
Ensembl chr 2:186,685,104...186,696,117
JBrowse link
G Cdc20b cell division cycle 20B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CDC20B mRNA CTD PMID:27935865 NCBI chr 2:44,916,806...44,947,860 JBrowse link
G Cdh26 cadherin 26 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CDH26 mRNA CTD PMID:27935865 NCBI chr 3:173,969,004...174,020,867
Ensembl chr 3:173,969,273...174,019,766
JBrowse link
G Cdhr1 cadherin-related family member 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CDHR1 mRNA CTD PMID:27935865 NCBI chr16:14,328,161...14,348,049
Ensembl chr16:14,328,160...14,348,046
JBrowse link
G Celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CELSR3 mRNA CTD PMID:27935865 NCBI chr 8:117,620,293...117,648,034
Ensembl chr 8:117,620,317...117,648,028
JBrowse link
G Cfd complement factor D multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CFD mRNA CTD PMID:27935865 NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943
JBrowse link
G Chi3l1 chitinase 3 like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CHIL1 mRNA CTD PMID:27935865 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802
JBrowse link
G Chodl chondrolectin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CHODL mRNA CTD PMID:27935865 NCBI chr11:17,537,980...17,560,305
Ensembl chr11:17,538,063...17,560,296
JBrowse link
G Chrdl1 chordin-like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CHRDL1 mRNA CTD PMID:27935865 NCBI chr  X:114,554,359...114,658,975
Ensembl chr  X:114,554,359...114,658,931
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CHRM2 mRNA CTD PMID:27935865 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Chst5 carbohydrate sulfotransferase 5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CHST5 mRNA CTD PMID:27935865 NCBI chr19:44,115,065...44,136,092
Ensembl chr19:44,115,120...44,135,387
JBrowse link
G Cidec cell death-inducing DFFA-like effector c multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CIDEC mRNA CTD PMID:27935865 NCBI chr 4:145,377,482...145,390,497
Ensembl chr 4:145,377,431...145,390,497
JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CKMT2 mRNA CTD PMID:27935865 NCBI chr 2:21,422,680...21,452,797
Ensembl chr 2:21,422,818...21,437,193
JBrowse link
G Clec4d C-type lectin domain family 4, member D multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CLEC4D mRNA CTD PMID:27935865 NCBI chr 4:156,253,084...156,264,766
Ensembl chr 4:156,253,079...156,264,769
JBrowse link
G Clec4e C-type lectin domain family 4, member E multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CLEC4E mRNA CTD PMID:27935865 NCBI chr 4:156,271,087...156,276,243
Ensembl chr 4:156,270,920...156,276,304
JBrowse link
G Cnn1 calponin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CNN1 mRNA CTD PMID:27935865 NCBI chr 8:23,113,083...23,121,748
Ensembl chr 8:23,113,048...23,121,761
JBrowse link
G Cntfr ciliary neurotrophic factor receptor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CNTFR mRNA CTD PMID:27935865 NCBI chr 5:58,041,114...58,078,687
Ensembl chr 5:58,041,146...58,078,545
JBrowse link
G Colq collagen like tail subunit of asymmetric acetylcholinesterase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of COLQ mRNA CTD PMID:27935865 NCBI chr16:7,626,380...7,681,621
Ensembl chr16:7,627,603...7,681,576
JBrowse link
G Cox7a1 cytochrome c oxidase subunit 7A1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of COX7A1 mRNA CTD PMID:27935865 NCBI chr 1:88,619,619...88,650,672
Ensembl chr 1:91,071,493...91,074,294
Ensembl chr 1:91,071,493...91,074,294
JBrowse link
G Cplx1 complexin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CPLX1 mRNA CTD PMID:27935865 NCBI chr14:2,194,895...2,226,610
Ensembl chr14:2,194,933...2,226,598
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of CREB1 mRNA] CTD PMID:29891994 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CREB3L3 mRNA CTD PMID:27935865 NCBI chr 7:11,490,852...11,499,287
Ensembl chr 7:11,490,852...11,499,282
JBrowse link
G Crisp3 cysteine-rich secretory protein 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CRISP3 mRNA CTD PMID:27935865 NCBI chr 9:24,047,405...24,088,066
Ensembl chr 9:24,066,303...24,088,064
JBrowse link
G Crispld1 cysteine-rich secretory protein LCCL domain containing 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CRISPLD1 mRNA CTD PMID:27935865 NCBI chr 5:663,750...711,033
Ensembl chr 5:670,754...711,033
JBrowse link
G Cryl1 crystallin, lambda 1 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of CRYL1 mRNA] CTD PMID:29891994 NCBI chr15:37,543,727...37,663,586
Ensembl chr15:37,543,727...37,663,584
JBrowse link
G Csf3 colony stimulating factor 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CSF3 mRNA CTD PMID:27935865 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Csf3r colony stimulating factor 3 receptor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CSF3R mRNA CTD PMID:27935865 NCBI chr 5:144,031,353...144,051,966
Ensembl chr 5:144,031,402...144,051,600
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of CSRP1 mRNA] CTD PMID:29891994 NCBI chr13:52,553,843...52,575,054
Ensembl chr13:52,553,775...52,575,051
JBrowse link
G Ctsc cathepsin C multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of CTSC mRNA] CTD PMID:29891994 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CXCL12 mRNA CTD PMID:27935865 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CXCL2 mRNA CTD PMID:27935865 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CXCL3 mRNA CTD PMID:27935865 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CXCL5 mRNA CTD PMID:27935865 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CXCR2 mRNA CTD PMID:27935865 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CYP2E1 mRNA CTD PMID:27935865 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CYP4F18 mRNA CTD PMID:27935865 NCBI chr16:19,501,680...19,528,935
Ensembl chr16:19,410,810...19,528,999
JBrowse link
G Cys1 cystin 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CYS1 mRNA CTD PMID:27935865 NCBI chr 6:43,844,937...43,862,131
Ensembl chr 6:43,844,937...43,862,131
JBrowse link
G Dcaf12l1 DDB1 and CUL4 associated factor 12-like 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of DCAF12L1 mRNA CTD PMID:27935865 NCBI chr  X:131,340,045...131,344,038
Ensembl chr  X:131,340,045...131,343,853
JBrowse link
G Dchs1 dachsous cadherin-related 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of DCHS1 mRNA CTD PMID:27935865 NCBI chr 1:170,594,981...170,629,062
Ensembl chr 1:170,594,822...170,628,915
JBrowse link
G Degs2 delta(4)-desaturase, sphingolipid 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of DEGS2 mRNA CTD PMID:27935865 NCBI chr 6:132,591,968...132,608,600
Ensembl chr 6:132,591,969...132,608,600
JBrowse link
G Derl3 derlin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of DERL3 mRNA CTD PMID:27935865 NCBI chr20:13,692,102...13,707,645
Ensembl chr20:13,704,314...13,706,205
JBrowse link
G Dhdh dihydrodiol dehydrogenase multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of DHDH mRNA] CTD PMID:29891994 NCBI chr 1:101,465,937...101,476,867
Ensembl chr 1:101,466,677...101,476,867
JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of DMBT1 mRNA; XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of DMBT1 mRNA] CTD PMID:27935865, PMID:29891994 NCBI chr 1:201,620,642...201,689,905
NCBI chr 1:203,149,414...203,228,705
JBrowse link
G Dmrta1 DMRT-like family A1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of DMRTA1 mRNA CTD PMID:27935865 NCBI chr 5:108,278,217...108,284,757
Ensembl chr 5:108,278,217...108,284,757
JBrowse link
G Dpt dermatopontin multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of DPT mRNA CTD PMID:27935865 NCBI chr13:83,073,307...83,102,404
Ensembl chr13:83,073,544...83,102,401
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of DRD1 mRNA CTD PMID:27935865 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Edn3 endothelin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of EDN3 mRNA CTD PMID:27935865 NCBI chr 3:172,856,730...172,879,276
Ensembl chr 3:172,856,733...172,880,450
JBrowse link
G Eef1a2 eukaryotic translation elongation factor 1 alpha 2 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of EEF1A2 mRNA] CTD PMID:29891994 NCBI chr 3:176,657,104...176,666,282
Ensembl chr 3:176,657,107...176,666,282
JBrowse link
G Egf epidermal growth factor multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of EGF mRNA CTD PMID:27935865 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Epha3 Eph receptor A3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of EPHA3 mRNA CTD PMID:27935865 NCBI chr11:421,253...783,037
Ensembl chr11:421,135...782,954
JBrowse link
G Epha5 EPH receptor A5 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of EPHA5 mRNA CTD PMID:27935865 NCBI chr14:25,589,312...25,958,258
Ensembl chr14:25,589,762...25,958,227
JBrowse link
G Epyc epiphycan multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of EPYC mRNA CTD PMID:27935865 NCBI chr 7:38,897,278...38,934,989
Ensembl chr 7:38,897,278...38,934,985
JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of F2RL1 mRNA] CTD PMID:29891994 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of F2RL3 mRNA CTD PMID:27935865 NCBI chr16:18,817,797...18,819,790
Ensembl chr16:18,814,622...18,819,833
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of F3 mRNA] CTD PMID:29891994 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fam13c family with sequence similarity 13, member C multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of FAM13C mRNA CTD PMID:27935865 NCBI chr20:19,358,869...19,470,212
Ensembl chr20:19,360,230...19,479,325
JBrowse link
G Fat2 FAT atypical cadherin 2 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of FAT2 mRNA] CTD PMID:29891994 NCBI chr10:40,583,025...40,682,598
Ensembl chr10:40,584,403...40,657,861
JBrowse link
G Fbln7 fibulin 7 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of FBLN7 mRNA CTD PMID:27935865 NCBI chr 3:121,407,981...121,441,660
Ensembl chr 3:121,408,146...121,440,787
JBrowse link
G Fbxo40 F-box protein 40 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of FBXO40 mRNA CTD PMID:27935865 NCBI chr11:66,713,913...66,731,195
Ensembl chr11:66,713,888...66,731,198
JBrowse link
G Fcrl2 Fc receptor-like 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of FCRLS mRNA CTD PMID:27935865 NCBI chr 2:186,594,442...186,605,115
Ensembl chr 2:186,595,051...186,606,172
JBrowse link
G Fhod3 formin homology 2 domain containing 3 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of FHOD3 mRNA] CTD PMID:29891994 NCBI chr18:16,650,786...17,332,209
Ensembl chr18:16,650,806...17,332,210
JBrowse link
G Foxn4 forkhead box N4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of FOXN4 mRNA CTD PMID:27935865 NCBI chr12:48,101,012...48,121,281
Ensembl chr12:48,101,673...48,121,270
JBrowse link
G Fpr2 formyl peptide receptor 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of FPR2 mRNA CTD PMID:27935865 NCBI chr 1:59,800,558...59,809,507
Ensembl chr 1:59,800,984...59,802,401
JBrowse link
G Frem1 Fras1 related extracellular matrix 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of FREM1 mRNA CTD PMID:27935865 NCBI chr 5:101,018,009...101,166,794
Ensembl chr 5:101,020,448...101,166,651
JBrowse link
G Frmpd4 FERM and PDZ domain containing 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of FRMPD4 mRNA CTD PMID:27935865 NCBI chr  X:27,231,648...28,206,890
Ensembl chr  X:28,072,826...28,204,260
JBrowse link
G Frzb frizzled-related protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of FRZB mRNA CTD PMID:27935865 NCBI chr 3:67,635,604...67,668,772
Ensembl chr 3:67,635,607...67,668,772
JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of GABRA4 mRNA CTD PMID:27935865 NCBI chr14:39,154,072...39,230,994
Ensembl chr14:39,154,529...39,231,695
JBrowse link
G Gal3st2 galactose-3-O-sulfotransferase 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of GAL3ST2 mRNA CTD PMID:27935865 NCBI chr 9:100,982,996...100,994,226
Ensembl chr 9:100,990,523...100,993,206
JBrowse link
G Gask1a golgi associated kinase 1A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of GASK1A mRNA CTD PMID:27935865 NCBI chr 8:130,581,072...130,614,118
Ensembl chr 8:130,581,062...130,612,510
JBrowse link
G Gcnt4 glucosaminyl (N-acetyl) transferase 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of GCNT4 mRNA CTD PMID:27935865 Ensembl chr 2:27,713,880...27,780,119 JBrowse link
G Gdf10 growth differentiation factor 10 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of GDF10 mRNA CTD PMID:27935865 NCBI chr16:10,250,508...10,262,383
Ensembl chr16:10,250,404...10,263,150
JBrowse link
G Gfra3 GDNF family receptor alpha 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of GFRA3 mRNA CTD PMID:27935865 NCBI chr18:27,491,860...27,520,133
Ensembl chr18:27,491,845...27,520,295
JBrowse link
G Gja3 gap junction protein, alpha 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of GJA3 mRNA CTD PMID:27935865 NCBI chr15:37,298,607...37,325,370
Ensembl chr15:37,299,738...37,325,178
JBrowse link
G Gprasp2 G protein-coupled receptor associated sorting protein 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of GPRASP2 mRNA CTD PMID:27935865 NCBI chr  X:106,357,240...106,363,455
Ensembl chr  X:106,360,393...106,363,300
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of GSTK1 mRNA] CTD PMID:29891994 NCBI chr 4:71,621,777...71,626,096
Ensembl chr 4:71,621,729...71,626,107
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of GSTZ1 mRNA] CTD PMID:29891994 NCBI chr 6:111,176,798...111,187,246
Ensembl chr 6:111,176,798...111,187,244
JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of HES1 mRNA] CTD PMID:29891994 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hhip Hedgehog-interacting protein multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of HHIP mRNA CTD PMID:27935865 NCBI chr19:31,525,134...31,614,487
Ensembl chr19:31,524,671...31,614,246
JBrowse link
G Hsd17b8 hydroxysteroid (17-beta) dehydrogenase 8 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of HSD17B8 mRNA] CTD PMID:29891994 NCBI chr20:3,817,212...3,819,316
Ensembl chr20:3,817,179...3,819,235
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of HTR2B mRNA CTD PMID:27935865 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of IDH2 mRNA] CTD PMID:29891994 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of IDO1 mRNA CTD PMID:27935865 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Ifi27l2b interferon, alpha-inducible protein 27 like 2B multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of IFI27L2 mRNA] CTD PMID:29891994 NCBI chr 6:127,336,305...127,337,791
Ensembl chr 6:127,336,305...127,337,791
JBrowse link
G Igll1 immunoglobulin lambda-like polypeptide 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of IGLL1 mRNA CTD PMID:27935865 NCBI chr11:88,388,378...88,391,524
Ensembl chr11:88,388,378...88,391,370
JBrowse link
G Il19 interleukin 19 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of IL19 mRNA CTD PMID:27935865 NCBI chr13:47,663,592...47,677,869
Ensembl chr13:47,664,080...47,670,407
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of IL1B mRNA CTD PMID:27935865 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Inmt indolethylamine N-methyltransferase multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of INMT mRNA CTD PMID:27935865 NCBI chr 4:85,381,907...85,386,203
Ensembl chr 4:85,381,889...85,386,231
JBrowse link
G Irf7 interferon regulatory factor 7 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of IRF7 mRNA] CTD PMID:29891994 NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of IRS2 mRNA] CTD PMID:29891994 NCBI chr16:83,824,515...83,848,569
Ensembl chr16:83,824,430...83,848,684
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of ISG15 mRNA] CTD PMID:29891994 NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of ITPR1 mRNA] CTD PMID:29891994 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
JBrowse link
G Itpr3 inositol 1,4,5-trisphosphate receptor, type 3 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of ITPR3 mRNA] CTD PMID:29891994 NCBI chr20:5,645,894...5,711,702
Ensembl chr20:5,646,097...5,711,702
JBrowse link
G Jchain joining chain of multimeric IgA and IgM multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of JCHAIN mRNA CTD PMID:27935865 NCBI chr14:21,176,841...21,183,731
Ensembl chr14:21,177,237...21,183,542
JBrowse link
G Kank4 KN motif and ankyrin repeat domains 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of KANK4 mRNA CTD PMID:27935865 NCBI chr 5:117,376,425...117,440,643
Ensembl chr 5:117,376,423...117,440,254
JBrowse link
G Kbtbd12 kelch repeat and BTB domain containing 12 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of KBTBD12 mRNA CTD PMID:27935865 NCBI chr 4:120,492,541...120,567,755
Ensembl chr 4:120,551,599...120,559,078
JBrowse link
G Kcna1 potassium voltage-gated channel subfamily A member 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of KCNA1 mRNA CTD PMID:27935865 NCBI chr 4:159,190,781...159,192,526
Ensembl chr 4:159,190,804...159,192,526
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of KCNMA1 mRNA CTD PMID:27935865 NCBI chr15:344,204...1,048,849
Ensembl chr15:344,360...1,047,956
JBrowse link
G Klhl13 kelch-like family member 13 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of KLHL13 mRNA CTD PMID:27935865 NCBI chr  X:121,578,965...121,735,014
Ensembl chr  X:121,578,940...121,731,543
JBrowse link
G Klhl33 kelch-like family member 33 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of KLHL33 mRNA CTD PMID:27935865 NCBI chr15:27,811,226...27,819,808
Ensembl chr15:27,813,393...27,815,261
JBrowse link
G Klhl4 kelch-like family member 4 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of KLHL4 mRNA CTD PMID:27935865 NCBI chr  X:86,125,929...86,229,565
Ensembl chr  X:86,126,157...86,229,563
JBrowse link
G Klk6 kallikrein related-peptidase 6 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of KLK6 mRNA CTD PMID:27935865 NCBI chr 1:99,762,195...99,769,486
Ensembl chr 1:99,762,253...99,769,488
JBrowse link
G Kng2 kininogen 2 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of KNG2 mRNA CTD PMID:27935865 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Krt16 keratin 16 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of KRT16 mRNA CTD PMID:27935865 NCBI chr10:88,149,210...88,152,167
Ensembl chr10:88,149,345...88,152,064
JBrowse link
G Krt84 keratin 84 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of KRT84 mRNA CTD PMID:27935865 NCBI chr 7:143,180,212...143,187,684
Ensembl chr 7:143,179,835...143,187,648
JBrowse link
G Letmd1 LETM1 domain containing 1 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of LETMD1 mRNA] CTD PMID:29891994 NCBI chr 7:142,106,364...142,119,900
Ensembl chr 7:142,106,465...142,119,899
JBrowse link
G Lin28a lin-28 homolog A multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of LIN28A mRNA CTD PMID:27935865 NCBI chr 5:152,230,343...152,247,873
Ensembl chr 5:152,230,343...152,247,332
JBrowse link
G Lipf lipase F, gastric type multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of LIPF mRNA CTD PMID:27935865 NCBI chr 1:252,284,464...252,302,811
Ensembl chr 1:252,284,464...252,302,811
JBrowse link
G Lipn lipase, family member N multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of LIPN mRNA CTD PMID:27935865 NCBI chr 1:252,375,941...252,394,226
Ensembl chr 1:252,375,933...252,396,460
JBrowse link
G Lman1l lectin, mannose-binding, 1 like multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of LMAN1L mRNA CTD PMID:27935865 NCBI chr 8:62,386,806...62,400,370
Ensembl chr 8:62,386,806...62,399,648
JBrowse link
G Lmo4 LIM domain only 4 multiple interactions ISO XL147 inhibits the reaction [N-nitroso-tris-chloroethylurea results in increased expression of LMO4 mRNA] CTD PMID:29891994 NCBI chr 2:250,218,635...250,235,435
Ensembl chr 2:250,218,641...250,241,673
JBrowse link
G Lmod3 leiomodin 3 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of LMOD3 mRNA CTD PMID:27935865 NCBI chr 4:129,604,378...129,619,136
Ensembl chr 4:129,604,267...129,619,142
JBrowse link
G LOC100912509 intermediate filament tail domain-containing protein 1-like multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of LMNTD1 mRNA CTD PMID:27935865 NCBI chr 4:180,141,742...180,153,948
Ensembl chr 4:180,141,986...180,153,906
JBrowse link
G LOC102550598 small proline-rich protein 2I-like multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of SPRR2G mRNA CTD PMID:27935865 NCBI chr 2:192,520,019...192,521,188
Ensembl chr 2:192,520,733...192,520,960
JBrowse link
G LOC690948 similar to paired-Ig-like receptor A11 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of LILRA6 mRNA CTD PMID:27935865 NCBI chr 1:63,963,855...63,971,869
Ensembl chr 1:63,964,155...63,967,366
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of LRG1 mRNA CTD PMID:27935865 NCBI chr 9:10,952,424...10,954,664
Ensembl chr 9:10,952,374...10,954,681
JBrowse link
G Lrrc3b leucine rich repeat containing 3B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of LRRC3B mRNA CTD PMID:27935865 NCBI chr15:11,221,161...11,299,563
Ensembl chr15:11,298,478...11,299,257
JBrowse link
G Lrrc4b leucine rich repeat containing 4B multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of LRRC4B mRNA CTD PMID:27935865 NCBI chr 1:100,434,418...100,468,914
Ensembl chr 1:100,447,998...100,468,868
JBrowse link
G Mamstr MEF2 activating motif and SAP domain containing transcriptional regulator multiple interactions ISO [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of MAMSTR mRNA CTD PMID:27935865 NCBI chr 1:101,621,733...101,628,379
Ensembl chr 1:101,623,308...101,627,609
JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha multiple interactions ISO XL147 inhibits the reaction