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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:nitenpyram
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Accession:CHEBI:39171 term browser browse the term
Definition:A C-nitro compound consisting of 2-nitroethene-1,1-diamine where one of the nitrogens bears ethyl and (6-chloro-3-pyridinyl)methyl while the other nitrogen carries a methyl group.
Synonyms:exact_synonym: N-[(6-chloropyridin-3-yl)methyl]-N-ethyl-N'-methyl-2-nitroethene-1,1-diamine
 related_synonym: Formula=C11H15ClN4O2;   InChI=1S/C11H15ClN4O2/c1-3-15(11(13-2)8-16(17)18)7-9-4-5-10(12)14-6-9/h4-6,8,13H,3,7H2,1-2H3;   InChIKey=CFRPSFYHXJZSBI-UHFFFAOYSA-N;   SMILES=[H]C(=C(NC)N(CC)Cc1ccc(Cl)nc1)[N+]([O-])=O
 xref: Beilstein:8553513
 xref_mesh: MESH:C464843
 xref: PMID:10789501;   PMID:21714058;   Reaxys:8553513


show annotations for term's descendants           Sort by:
nitenpyram term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt2 AKT serine/threonine kinase 2 decreases expression ISO nitenpyram results in decreased expression of AKT2 mRNA CTD PMID:35568224 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Akt3 AKT serine/threonine kinase 3 decreases expression ISO nitenpyram results in decreased expression of AKT3 mRNA CTD PMID:35568224 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708 		JBrowse link
G Atm ATM serine/threonine kinase increases expression ISO nitenpyram results in increased expression of ATM mRNA CTD PMID:35568224 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atr ATR serine/threonine kinase decreases expression ISO nitenpyram results in decreased expression of ATR mRNA CTD PMID:35568224 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO nitenpyram results in increased expression of BAX mRNA CTD PMID:35568224 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Cd36 CD36 molecule increases expression ISO nitenpyram results in increased expression of CD36 mRNA CTD PMID:35568224 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO nitenpyram results in increased expression of CDKN1A mRNA CTD PMID:35568224 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP nitenpyram results in increased activity of [NACHRALPHA1 protein co-treated with CHRNB2 protein] CTD PMID:16981889 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Egf epidermal growth factor decreases expression ISO nitenpyram results in decreased expression of EGF mRNA CTD PMID:35568224 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression ISO nitenpyram results in decreased expression of GADD45A mRNA CTD PMID:35568224 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G H2ax H2A.X variant histone increases expression ISO nitenpyram results in increased expression of H2AX mRNA CTD PMID:35568224 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO nitenpyram results in increased expression of MDM2 mRNA CTD PMID:35568224 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 increases activity ISO nitenpyram results in increased activity of SLC22A1 protein CTD PMID:31364238 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases activity ISO nitenpyram results in decreased activity of SLC22A2 protein CTD PMID:31364238 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 increases activity ISO nitenpyram results in increased activity of SLCO2B1 protein CTD PMID:31364238 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO nitenpyram results in increased expression of TP53 mRNA CTD PMID:35568224 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      application 19661
        pesticide 17927
          insecticide 16518
            neonicotinoid insectide 880
              nitenpyram 16
                (E)-nitenpyram 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            organic molecule 19686
                              organic cyclic compound 19498
                                organic heterocyclic compound 18876
                                  organic heteromonocyclic compound 17804
                                    pyridines 11520
                                      chloropyridine 5754
                                        monochloropyridine 488
                                          2-chloropyridine 486
                                            nitenpyram 16
                                              (E)-nitenpyram 0
paths to the root