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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:monochloropyridine
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Accession:CHEBI:39172 term browser browse the term
Definition:A chloropyridine in which only one chlorine is attached to the pyridine ring.
Synonyms:exact_synonym: chloropyridine
 related_synonym: Formula=C5H4ClN


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acetamiprid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actrt2 actin-related protein T2 decreases expression EXP acetamiprid results in decreased expression of ACTRT2 mRNA CTD PMID:27782041 NCBI chr 5:172,077,290...172,078,690
Ensembl chr 5:172,077,282...172,078,760
JBrowse link
G Asap2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 increases expression EXP acetamiprid results in increased expression of ASAP2 mRNA CTD PMID:27782041 NCBI chr 6:43,231,178...43,348,606
Ensembl chr 6:43,234,526...43,343,551
JBrowse link
G B3gnt9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 increases expression EXP acetamiprid results in increased expression of B3GNT9 mRNA CTD PMID:27782041 NCBI chr19:37,208,061...37,212,400
Ensembl chr19:37,208,825...37,210,412
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H increases expression EXP acetamiprid results in increased expression of CACNA1H mRNA CTD PMID:27782041 NCBI chr10:14,730,932...14,789,201
Ensembl chr10:14,730,941...14,788,617
JBrowse link
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 decreases expression EXP acetamiprid results in decreased expression of CACNG1 mRNA CTD PMID:27782041 NCBI chr10:95,921,479...95,934,170
Ensembl chr10:95,921,174...95,934,345
JBrowse link
G Card11 caspase recruitment domain family, member 11 increases expression EXP acetamiprid results in increased expression of CARD11 mRNA CTD PMID:27782041 NCBI chr12:15,700,600...15,844,512
Ensembl chr12:15,700,825...15,844,512
JBrowse link
G Cat catalase decreases activity ISO acetamiprid results in decreased activity of CAT protein CTD PMID:31935421 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit decreases expression ISO acetamiprid results in decreased expression of CHRNA4 mRNA CTD PMID:30103633 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit decreases expression ISO acetamiprid results in decreased expression of CHRNA7 mRNA CTD PMID:30103633 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit decreases expression
multiple interactions
ISO
EXP
acetamiprid results in decreased expression of CHRNB2
acetamiprid results in increased activity of [NACHRA1 protein co-treated with CHRNB2 protein]; acetamiprid results in increased activity of [NACHRA8 protein co-treated with CHRNB2 protein]
CTD PMID:16981889 PMID:25459289 PMID:27669271 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression
EXP
ISO
Vitamin E inhibits the reaction [acetamiprid results in decreased expression of CYP11A mRNA]; Vitamin E inhibits the reaction [acetamiprid results in decreased expression of CYP11A protein]
acetamiprid results in decreased expression of CYP11A1 mRNA
acetamiprid results in decreased expression of CYP11A1 mRNA; acetamiprid results in decreased expression of CYP11A1 protein
CTD PMID:28395332 PMID:30103633 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO acetamiprid results in decreased expression of CYP17A1 mRNA CTD PMID:30103633 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Dcdc2 doublecortin domain containing 2 increases expression
decreases expression
EXP acetamiprid results in increased expression of DCDC2 mRNA
acetamiprid results in decreased expression of DCDC2 mRNA
CTD PMID:27782041 NCBI chr17:41,838,201...42,031,265
Ensembl chr17:41,838,201...42,031,265
JBrowse link
G Des desmin decreases expression EXP acetamiprid results in decreased expression of DES mRNA CTD PMID:27782041 NCBI chr 9:82,556,574...82,564,288
Ensembl chr 9:82,556,573...82,564,294
JBrowse link
G F2rl2 coagulation factor II (thrombin) receptor-like 2 increases expression EXP acetamiprid results in increased expression of F2RL2 mRNA CTD PMID:27782041 NCBI chr 2:26,240,385...26,245,533
Ensembl chr 2:26,240,385...26,245,533
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 decreases expression ISO acetamiprid results in decreased expression of HSD17B1 mRNA CTD PMID:30103633 NCBI chr10:88,987,558...88,989,758
Ensembl chr10:88,987,558...88,989,757
JBrowse link
G Hspb7 heat shock protein family B (small) member 7 decreases expression EXP acetamiprid results in decreased expression of HSPB7 mRNA CTD PMID:27782041 NCBI chr 5:159,968,077...159,971,563
Ensembl chr 5:159,967,839...159,971,562
JBrowse link
G Iqcf1 IQ motif containing F1 decreases expression EXP acetamiprid results in decreased expression of IQCF1 mRNA CTD PMID:27782041 NCBI chr 8:115,191,919...115,195,599
Ensembl chr 8:115,193,146...115,195,668
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions
increases expression
EXP Vitamin E inhibits the reaction [acetamiprid results in increased expression of LHB protein] CTD PMID:28395332 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor decreases expression ISO acetamiprid results in decreased expression of LHR mRNA CTD PMID:30103633 NCBI chr 6:12,493,182...12,554,482
Ensembl chr 6:12,493,943...12,554,439
JBrowse link
G Lmod2 leiomodin 2 decreases expression EXP acetamiprid results in decreased expression of LMOD2 mRNA CTD PMID:27782041 NCBI chr 4:51,553,439...51,561,135
Ensembl chr 4:51,553,454...51,561,174
JBrowse link
G Mb myoglobin decreases expression EXP acetamiprid results in decreased expression of MB mRNA CTD PMID:27782041 NCBI chr 7:118,101,633...118,108,864
Ensembl chr 7:118,101,634...118,108,864
JBrowse link
G Mcmdc2 minichromosome maintenance domain containing 2 increases expression EXP acetamiprid results in increased expression of MCMDC2 mRNA CTD PMID:27782041 NCBI chr 5:8,973,861...9,039,616
Ensembl chr 5:8,978,010...9,038,594
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO acetamiprid results in decreased expression of MKI67 mRNA CTD PMID:30103633 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Myog myogenin decreases expression EXP acetamiprid results in decreased expression of MYOG mRNA CTD PMID:27782041 NCBI chr13:51,126,459...51,129,048
Ensembl chr13:51,126,459...51,129,048
JBrowse link
G Nags N-acetylglutamate synthase decreases expression EXP acetamiprid results in decreased expression of NAGS mRNA CTD PMID:27782041 NCBI chr10:90,084,607...90,089,693
Ensembl chr10:90,085,559...90,089,693
JBrowse link
G Napb NSF attachment protein beta increases expression EXP acetamiprid results in increased expression of NAPB mRNA CTD PMID:27782041 NCBI chr 3:143,017,571...143,063,904
Ensembl chr 3:143,020,454...143,063,983
JBrowse link
G Ndufaf2 NADH:ubiquinone oxidoreductase complex assembly factor 2 decreases expression EXP acetamiprid results in decreased expression of NDUFAF2 mRNA CTD PMID:27782041 NCBI chr 2:39,322,145...39,434,535
Ensembl chr 2:39,321,741...39,434,560
JBrowse link
G Olr825 olfactory receptor 825 decreases expression EXP acetamiprid results in decreased expression of OLR825 mRNA CTD PMID:27782041 NCBI chr 4:148,544,958...148,545,941
Ensembl chr 4:148,544,958...148,545,941
JBrowse link
G Olr94 olfactory receptor 94 decreases expression EXP acetamiprid results in decreased expression of OLR94 mRNA CTD PMID:27782041 NCBI chr 1:168,470,190...168,471,161
Ensembl chr 1:168,470,190...168,471,161
JBrowse link
G Phf21b PHD finger protein 21B increases expression EXP acetamiprid results in increased expression of PHF21B mRNA CTD PMID:27782041 NCBI chr 7:125,649,688...125,720,694
Ensembl chr 7:125,649,688...125,718,986
JBrowse link
G Plac8 placenta associated 8 increases expression EXP acetamiprid results in increased expression of PLAC8 mRNA CTD PMID:27782041 NCBI chr14:10,692,799...10,714,556
Ensembl chr14:10,692,764...10,714,524
JBrowse link
G Slc22a1 solute carrier family 22 member 1 increases activity ISO acetamiprid results in increased activity of SLC22A1 protein CTD PMID:31364238 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases activity ISO acetamiprid results in decreased activity of SLC22A2 protein CTD PMID:31364238 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc22a8 solute carrier family 22 member 8 decreases activity ISO acetamiprid results in decreased activity of SLC22A8 protein CTD PMID:31364238 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
G Slc45a3 solute carrier family 45, member 3 increases expression EXP acetamiprid results in increased expression of SLC45A3 mRNA CTD PMID:27782041 NCBI chr13:48,745,855...48,766,283
Ensembl chr13:48,745,860...48,766,283
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 decreases expression EXP acetamiprid results in decreased expression of SLCO1B2 mRNA CTD PMID:27782041 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression
multiple interactions
EXP
ISO
acetamiprid results in decreased expression of STAR mRNA; acetamiprid results in decreased expression of STAR protein
Vitamin E inhibits the reaction [acetamiprid results in decreased expression of STAR mRNA]; Vitamin E inhibits the reaction [acetamiprid results in decreased expression of STAR protein]
CTD PMID:28395332 PMID:30103633 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Tada2b transcriptional adaptor 2B increases expression EXP acetamiprid results in increased expression of TADA2B mRNA CTD PMID:27782041 NCBI chr14:79,446,057...79,457,341
Ensembl chr14:79,446,057...79,457,333
JBrowse link
G Tnni2 troponin I2, fast skeletal type decreases expression EXP acetamiprid results in decreased expression of TNNI2 mRNA CTD PMID:27782041 NCBI chr 1:215,609,110...215,611,652
Ensembl chr 1:215,609,036...215,611,658
JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression ISO acetamiprid results in decreased expression of TOP2A mRNA CTD PMID:30103633 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Unc45b unc-45 myosin chaperone B decreases expression EXP acetamiprid results in decreased expression of UNC45B mRNA CTD PMID:27782041 NCBI chr10:70,262,340...70,290,445
Ensembl chr10:70,262,361...70,290,445
JBrowse link
imidacloprid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases activity EXP imidacloprid results in increased activity of ACHE protein CTD PMID:18080902 PMID:26024013 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Alb albumin multiple interactions EXP [imidacloprid co-treated with sodium arsenate] results in decreased expression of ALB protein CTD PMID:30033815 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Ampd1 adenosine monophosphate deaminase 1 decreases expression EXP imidacloprid results in decreased expression of AMPD1 mRNA CTD PMID:27782041 NCBI chr 2:205,568,934...205,589,961
Ensembl chr 2:205,568,935...205,590,021
JBrowse link
G Ar androgen receptor decreases expression ISO imidacloprid results in decreased expression of AR mRNA; imidacloprid results in decreased expression of AR protein CTD PMID:31780179 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP imidacloprid results in increased expression of BAX protein CTD PMID:27914857 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bche butyrylcholinesterase increases activity EXP imidacloprid results in increased activity of BCHE protein CTD PMID:18080902 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H increases expression EXP imidacloprid results in increased expression of CACNA1H mRNA CTD PMID:27782041 NCBI chr10:14,730,932...14,789,201
Ensembl chr10:14,730,941...14,788,617
JBrowse link
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 decreases expression EXP imidacloprid results in decreased expression of CACNG1 mRNA CTD PMID:27782041 NCBI chr10:95,921,479...95,934,170
Ensembl chr10:95,921,174...95,934,345
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 decreases expression
multiple interactions
ISO imidacloprid results in decreased expression of CAMKK2 protein
Dietary Fats promotes the reaction [imidacloprid results in decreased expression of CAMKK2 protein]
CTD PMID:27960282 NCBI chr12:39,253,409...39,302,601
Ensembl chr12:39,253,409...39,302,601
JBrowse link
G Cat catalase decreases activity
multiple interactions
EXP imidacloprid results in decreased activity of CAT protein
imidacloprid promotes the reaction [sodium arsenate results in decreased activity of CAT protein]; sodium arsenate promotes the reaction [imidacloprid results in decreased activity of CAT protein]
CTD PMID:20686345 PMID:30033815 PMID:30456172 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccdc81 coiled-coil domain containing 81 increases expression EXP imidacloprid results in increased expression of CCDC81 mRNA CTD PMID:27782041 NCBI chr 1:154,064,132...154,111,999
Ensembl chr 1:154,064,256...154,111,725
JBrowse link
G Cd36 CD36 molecule increases expression ISO imidacloprid results in increased expression of CD36 mRNA CTD PMID:27960282 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Celf6 CUGBP, Elav-like family member 6 increases expression EXP imidacloprid results in increased expression of CELF6 mRNA CTD PMID:27782041 NCBI chr 8:64,364,491...64,428,452
Ensembl chr 8:64,364,741...64,428,386
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 increases expression EXP imidacloprid results in increased expression of CHRM1 mRNA CTD PMID:26568164 NCBI chr 1:224,869,087...224,885,101
Ensembl chr 1:224,882,439...224,884,205
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 increases expression EXP imidacloprid results in increased expression of CHRM2 protein CTD PMID:18080902 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit multiple interactions EXP imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]; LYNX1 protein promotes the reaction [imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]]; LYPD1 protein promotes the reaction [imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]] CTD PMID:19619141 NCBI chr 3:60,445,657...60,460,724
Ensembl chr 3:60,445,666...60,460,724
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP
ISO
imidacloprid analog inhibits the reaction [Nicotine analog binds to [CHRNA4 protein co-treated with CHRNB2 protein]]; imidacloprid binds to [CHRNA4 protein co-treated with CHRNB2 protein]
imidacloprid inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]
CTD PMID:10377228 PMID:10728888 PMID:21538459 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP
ISO
[NACHRA8 protein co-treated with CHRNB2 protein] affects the susceptibility to imidacloprid; imidacloprid analog inhibits the reaction [Nicotine analog binds to [CHRNA4 protein co-treated with CHRNB2 protein]]; imidacloprid binds to [CHRNA4 protein co-treated with CHRNB2 protein]; imidacloprid binds to [NACHRA1 protein co-treated with CHRNB2 protein]; imidacloprid binds to [NACHRA2 protein co-treated with CHRNB2 protein]; imidacloprid binds to [NACHRALPHA1 protein co-treated with CHRNB2 protein]; imidacloprid binds to [NACHRALPHA2 protein co-treated with CHRNB2 protein]; imidacloprid binds to [NACHRALPHA3 protein co-treated with CHRNB2 protein]; imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]; imidacloprid results in increased activity of [NACHRA1 protein co-treated with CHRNB2 protein]; imidacloprid results in increased activity of [NACHRA1 protein co-treated with NACHRA2 protein co-treated with CHRNB2 protein]; imidacloprid results in increased activity of [NACHRA2 protein co-treated with CHRNB2 protein]; imidacloprid results in increased activity of [NACHRA8 protein co-treated with CHRNB2 protein]; LYNX1 protein promotes the reaction [imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]]; LYPD1 protein promotes the reaction [imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]]
imidacloprid inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]
CTD PMID:10377228 PMID:10728888 PMID:16291090 PMID:16981889 PMID:18824080 PMID:19046356 PMID:19619141 PMID:19849723 PMID:21538459 PMID:25459289 PMID:25613467 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Cldn1 claudin 1 decreases expression EXP imidacloprid results in decreased expression of CLDN1 mRNA CTD PMID:27792329 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Crb3 crumbs cell polarity complex component 3 increases expression EXP imidacloprid results in increased expression of CRB3 mRNA CTD PMID:27782041 NCBI chr 9:9,982,529...9,986,896
Ensembl chr 9:9,980,720...9,985,630
JBrowse link
G Ctnnd1 catenin delta 1 increases expression EXP imidacloprid results in increased expression of CTNND1 mRNA CTD PMID:27792329 NCBI chr 3:72,001,904...72,053,047
Ensembl chr 3:72,002,152...72,053,049
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression ISO imidacloprid results in decreased expression of CYP11A1 mRNA CTD PMID:31780179 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP
ISO
imidacloprid results in decreased expression of CYP17A1 mRNA CTD PMID:27782041 PMID:31780179 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity
affects expression
multiple interactions
ISO imidacloprid results in increased activity of CYP19A1 protein
imidacloprid affects the expression of CYP19A1 mRNA
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione affects the reaction [imidacloprid affects the expression of CYP19A1 mRNA]
CTD PMID:28750898 PMID:29701941 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 multiple interactions ISO [NADP co-treated with CYP3A4 protein] results in increased activity of imidacloprid analog CTD PMID:16153789 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G F2rl2 coagulation factor II (thrombin) receptor-like 2 increases expression EXP imidacloprid results in increased expression of F2RL2 mRNA CTD PMID:27782041 NCBI chr 2:26,240,385...26,245,533
Ensembl chr 2:26,240,385...26,245,533
JBrowse link
G Galnt7 polypeptide N-acetylgalactosaminyltransferase 7 increases expression EXP imidacloprid results in increased expression of GALNT7 mRNA CTD PMID:27782041 NCBI chr16:35,935,059...36,062,734
Ensembl chr16:35,934,970...36,062,719
JBrowse link
G Gfap glial fibrillary acidic protein increases expression EXP imidacloprid results in increased expression of GFAP protein CTD PMID:18080902 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP imidacloprid results in decreased expression of GJA1 mRNA CTD PMID:27792329 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity
multiple interactions
EXP imidacloprid results in increased activity of GPT protein
[imidacloprid co-treated with sodium arsenate] results in increased activity of GPT protein
CTD PMID:30033815 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
EXP imidacloprid promotes the reaction [sodium arsenate results in decreased activity of GSR protein]; sodium arsenate promotes the reaction [imidacloprid results in decreased activity of GSR protein] CTD PMID:30033815 PMID:30456172 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hao1 hydroxyacid oxidase 1 decreases expression EXP imidacloprid results in decreased expression of HAO1 mRNA CTD PMID:27782041 NCBI chr 3:127,444,900...127,500,709
Ensembl chr 3:127,444,902...127,500,709
JBrowse link
G Hjv hemojuvelin BMP co-receptor decreases expression EXP imidacloprid results in decreased expression of HJV mRNA CTD PMID:27782041 NCBI chr 2:198,655,437...198,659,318
Ensembl chr 2:198,655,437...198,659,317
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO imidacloprid results in decreased expression of HMGCR mRNA CTD PMID:31780179 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 decreases expression EXP imidacloprid results in decreased expression of HSD3B2 mRNA CTD PMID:27914857 NCBI chr 2:200,712,895...200,722,429
Ensembl chr 2:202,341,422...202,350,929
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 decreases expression ISO imidacloprid results in decreased expression of HSP90B1 protein CTD PMID:16884889 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO imidacloprid results in decreased expression of HSPA5 protein CTD PMID:16884889 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression ISO imidacloprid results in decreased expression of HSPB1 protein CTD PMID:16884889 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hspb7 heat shock protein family B (small) member 7 decreases expression EXP imidacloprid results in decreased expression of HSPB7 mRNA CTD PMID:27782041 NCBI chr 5:159,968,077...159,971,563
Ensembl chr 5:159,967,839...159,971,562
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C increases expression EXP imidacloprid results in increased expression of HTR2C mRNA CTD PMID:27782041 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Itpripl1 ITPRIP like 1 decreases expression EXP imidacloprid results in decreased expression of ITPRIPL1 mRNA CTD PMID:27782041 NCBI chr 3:119,616,473...119,619,865
Ensembl chr 3:119,616,945...119,619,865
JBrowse link
G Klk1 kallikrein 1 decreases expression EXP imidacloprid results in decreased expression of KLK1 mRNA CTD PMID:27782041 NCBI chr 1:100,131,562...100,135,556
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
JBrowse link
G Krt5 keratin 5 decreases expression EXP imidacloprid results in decreased expression of KRT5 mRNA CTD PMID:27782041 NCBI chr 7:143,320,142...143,324,536
Ensembl chr 7:143,316,920...143,453,546
JBrowse link
G Lep leptin multiple interactions
increases secretion
ISO Dietary Fats promotes the reaction [imidacloprid results in increased secretion of LEP protein]; imidacloprid promotes the reaction [Dietary Fats results in increased secretion of LEP protein] CTD PMID:27960282 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lynx1 Ly6/neurotoxin 1 multiple interactions EXP LYNX1 protein promotes the reaction [imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]] CTD PMID:19619141 NCBI chr 7:115,982,877...115,988,121
Ensembl chr 7:115,982,876...115,988,090
JBrowse link
G Lypd1 Ly6/Plaur domain containing 1 multiple interactions EXP LYPD1 protein promotes the reaction [imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]] CTD PMID:19619141 NCBI chr13:42,219,884...42,263,024
Ensembl chr13:42,219,887...42,263,024
JBrowse link
G Magel2 MAGE family member L2 increases expression EXP imidacloprid results in increased expression of MAGEL2 mRNA CTD PMID:27782041 NCBI chr 1:123,015,404...123,019,945
Ensembl chr 1:123,015,746...123,019,522
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO imidacloprid results in increased phosphorylation of MAPK1 protein CTD PMID:12460746 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO imidacloprid results in increased phosphorylation of MAPK3 protein CTD PMID:12460746 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mb myoglobin decreases expression EXP imidacloprid results in decreased expression of MB mRNA CTD PMID:27782041 NCBI chr 7:118,101,633...118,108,864
Ensembl chr 7:118,101,634...118,108,864
JBrowse link
G Mybpc2 myosin binding protein C2 increases expression EXP imidacloprid results in increased expression of MYBPC2 mRNA CTD PMID:27782041 NCBI chr 1:100,506,704...100,530,201
Ensembl chr 1:100,506,704...100,530,183
JBrowse link
G Mypn myopalladin decreases expression EXP imidacloprid results in decreased expression of MYPN mRNA CTD PMID:27782041 NCBI chr20:26,988,820...27,074,106
Ensembl chr20:26,988,774...27,074,138
JBrowse link
G Ndufaf2 NADH:ubiquinone oxidoreductase complex assembly factor 2 decreases expression EXP imidacloprid results in decreased expression of NDUFAF2 mRNA CTD PMID:27782041 NCBI chr 2:39,322,145...39,434,535
Ensembl chr 2:39,321,741...39,434,560
JBrowse link
G Neurog3 neurogenin 3 decreases expression EXP imidacloprid results in decreased expression of NEUROG3 mRNA CTD PMID:27782041 NCBI chr20:31,761,419...31,762,893
Ensembl chr20:31,761,405...31,762,893
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 decreases expression EXP imidacloprid results in decreased expression of NR5A1 mRNA CTD PMID:27914857 NCBI chr 3:22,998,900...23,020,441
Ensembl chr 3:22,999,616...23,020,441
JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like increases expression EXP imidacloprid results in increased expression of OASL mRNA CTD PMID:27782041 NCBI chr12:47,444,138...47,456,680
Ensembl chr12:47,444,104...47,456,894
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase increases expression EXP imidacloprid results in increased expression of OGG1 mRNA CTD PMID:27914857 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression
multiple interactions
ISO imidacloprid results in increased expression of PCK2 mRNA
Dietary Fats promotes the reaction [imidacloprid results in increased expression of PCK2 mRNA]; imidacloprid promotes the reaction [Dietary Fats results in increased expression of PCK2 mRNA]
CTD PMID:27960282 NCBI chr15:34,216,735...34,224,357
Ensembl chr15:34,216,833...34,224,193
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO imidacloprid results in increased expression of PDK4 mRNA CTD PMID:27960282 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase multiple interactions
increases expression
EXP imidacloprid promotes the reaction [Nicotine results in increased expression of PNMT protein]
imidacloprid results in increased expression of PNMT protein
CTD PMID:29246838 NCBI chr10:86,340,893...86,342,501
Ensembl chr10:86,340,940...86,342,858
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO imidacloprid results in decreased expression of PPARA mRNA CTD PMID:27960282 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression ISO imidacloprid results in decreased expression of PPARGC1A protein CTD PMID:27960282 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Prl prolactin multiple interactions ISO [mancozeb co-treated with imidacloprid] results in increased expression of PRL protein CTD PMID:24530807 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Rbfox2 RNA binding fox-1 homolog 2 increases expression EXP imidacloprid results in increased expression of RBFOX2 mRNA CTD PMID:27782041 NCBI chr 7:118,157,093...118,396,733
Ensembl chr 7:118,156,946...118,396,728
JBrowse link
G Sirt1 sirtuin 1 decreases expression ISO imidacloprid results in decreased expression of SIRT1 protein CTD PMID:27960282 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc22a1 solute carrier family 22 member 1 increases activity ISO imidacloprid results in increased activity of SLC22A1 protein CTD PMID:31364238 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases activity ISO imidacloprid results in decreased activity of SLC22A2 protein CTD PMID:31364238 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc22a8 solute carrier family 22 member 8 decreases activity ISO imidacloprid results in decreased activity of SLC22A8 protein CTD PMID:31364238 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
G Slc2a2 solute carrier family 2 member 2 increases expression EXP imidacloprid results in increased expression of SLC2A2 mRNA CTD PMID:28850943 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Slc2a3 solute carrier family 2 member 3 increases expression EXP imidacloprid results in increased expression of SLC2A3 mRNA CTD PMID:27782041 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856
Ensembl chr 4:155,408,233...155,631,856
JBrowse link
G Slc2a4 solute carrier family 2 member 4 decreases expression ISO
EXP
imidacloprid results in decreased expression of SLC2A4 mRNA
imidacloprid results in decreased expression of SLC2A4 mRNA; imidacloprid results in decreased expression of SLC2A4 protein
CTD PMID:27960282 PMID:28850943 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO imidacloprid results in increased expression of SREBF1 mRNA CTD PMID:27960282 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression ISO imidacloprid results in decreased expression of STAR mRNA CTD PMID:31780179 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Tacr3 tachykinin receptor 3 increases expression EXP imidacloprid results in increased expression of TACR3 mRNA CTD PMID:27782041 NCBI chr 2:240,021,152...240,118,971
Ensembl chr 2:240,021,152...240,118,971
JBrowse link
G Tada2b transcriptional adaptor 2B increases expression EXP imidacloprid results in increased expression of TADA2B mRNA CTD PMID:27782041 NCBI chr14:79,446,057...79,457,341
Ensembl chr14:79,446,057...79,457,333
JBrowse link
G Th tyrosine hydroxylase multiple interactions
increases expression
EXP [conotoxin AuIB co-treated with triethyl-(beta-4-stilbenoxyethyl)ammonium co-treated with ZM 241385] inhibits the reaction [imidacloprid promotes the reaction [Nicotine results in increased expression of TH mRNA]]; [conotoxin AuIB co-treated with triethyl-(beta-4-stilbenoxyethyl)ammonium co-treated with ZM 241385] inhibits the reaction [imidacloprid results in increased expression of TH mRNA]; [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with exoenzyme C3, Clostridium botulinum] inhibits the reaction [imidacloprid results in increased expression of TH mRNA]; conotoxin AuIB inhibits the reaction [imidacloprid promotes the reaction [Acetylcholine results in increased expression of TH mRNA]]; conotoxin AuIB inhibits the reaction [imidacloprid promotes the reaction [Nicotine results in increased expression of TH mRNA]]; conotoxin AuIB inhibits the reaction [imidacloprid results in increased expression of TH mRNA]; exoenzyme C3, Clostridium botulinum inhibits the reaction [imidacloprid results in increased expression of TH mRNA]; imidacloprid promotes the reaction [Acetylcholine results in increased expression of TH mRNA]; imidacloprid promotes the reaction [Nicotine results in increased expression of TH mRNA]; imidacloprid promotes the reaction [Nicotine results in increased expression of TH protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [imidacloprid results in increased expression of TH mRNA]; triethyl-(beta-4-stilbenoxyethyl)ammonium inhibits the reaction [imidacloprid promotes the reaction [Acetylcholine results in increased expression of TH mRNA]]; triethyl-(beta-4-stilbenoxyethyl)ammonium inhibits the reaction [imidacloprid promotes the reaction [Nicotine results in increased expression of TH mRNA]]; triethyl-(beta-4-stilbenoxyethyl)ammonium inhibits the reaction [imidacloprid results in increased expression of TH mRNA]; ZM 241385 inhibits the reaction [imidacloprid promotes the reaction [Nicotine results in increased expression of TH mRNA]]; ZM 241385 inhibits the reaction [imidacloprid results in increased expression of TH mRNA]
imidacloprid results in increased expression of TH mRNA; imidacloprid results in increased expression of TH protein
CTD PMID:29246838 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Thrb thyroid hormone receptor beta affects binding ISO imidacloprid binds to THRB protein CTD PMID:28973306 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
G Tjp1 tight junction protein 1 decreases expression EXP imidacloprid results in decreased expression of TJP1 mRNA CTD PMID:27792329 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO Dietary Fats promotes the reaction [imidacloprid results in increased expression of TNF mRNA]; imidacloprid promotes the reaction [Dietary Fats results in increased expression of TNF mRNA] CTD PMID:27960282 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnni2 troponin I2, fast skeletal type decreases expression EXP imidacloprid results in decreased expression of TNNI2 mRNA CTD PMID:27782041 NCBI chr 1:215,609,110...215,611,652
Ensembl chr 1:215,609,036...215,611,658
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO [mancozeb co-treated with imidacloprid] results in increased expression of TSHB protein CTD PMID:24530807 NCBI chr 2:205,207,799...205,215,199
Ensembl chr 2:205,207,799...205,212,681
JBrowse link
G Tspo translocator protein decreases expression ISO imidacloprid results in decreased expression of TSPO mRNA CTD PMID:31780179 NCBI chr 7:124,460,358...124,470,610
Ensembl chr 7:124,460,358...124,470,609
JBrowse link
G Txk TXK tyrosine kinase increases expression EXP imidacloprid results in increased expression of TXK mRNA CTD PMID:27782041 NCBI chr14:38,029,809...38,085,822
Ensembl chr14:38,030,189...38,085,919
JBrowse link
G Unc45b unc-45 myosin chaperone B decreases expression EXP imidacloprid results in decreased expression of UNC45B mRNA CTD PMID:27782041 NCBI chr10:70,262,340...70,290,445
Ensembl chr10:70,262,361...70,290,445
JBrowse link
G Vcl vinculin decreases expression EXP imidacloprid results in decreased expression of VCL mRNA CTD PMID:27792329 NCBI chr15:3,455,211...3,544,738
Ensembl chr15:3,455,211...3,544,702
JBrowse link
nitenpyram term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP nitenpyram results in increased activity of [NACHRA1 protein co-treated with CHRNB2 protein] CTD PMID:16981889 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Slc22a1 solute carrier family 22 member 1 increases activity ISO nitenpyram results in increased activity of SLC22A1 protein CTD PMID:31364238 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases activity ISO nitenpyram results in decreased activity of SLC22A2 protein CTD PMID:31364238 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 increases activity ISO nitenpyram results in increased activity of SLCO2B1 protein CTD PMID:31364238 NCBI chr 1:164,623,313...164,671,612
Ensembl chr 1:164,623,599...164,671,577
JBrowse link
thiacloprid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC2 mRNA CTD PMID:32745781 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC3 mRNA CTD PMID:32745781 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Ache acetylcholinesterase decreases activity EXP
ISO
thiacloprid results in decreased activity of ACHE protein CTD PMID:21251949 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of ACOX1 mRNA CTD PMID:32736067 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression
multiple interactions
ISO thiacloprid results in increased expression of ALDH1A1 mRNA
[thiacloprid co-treated with enilconazole] results in decreased expression of ALDH1A1 mRNA
CTD PMID:32201337 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Cat catalase decreases activity
multiple interactions
decreases expression
EXP thiacloprid results in decreased activity of CAT protein
Polysaccharides inhibits the reaction [thiacloprid results in decreased activity of CAT protein]; Polysaccharides inhibits the reaction [thiacloprid results in decreased expression of CAT mRNA]
CTD PMID:28692354 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cd36 CD36 molecule multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CD36 mRNA CTD PMID:32736067 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Ces2h carboxylesterase 2H multiple interactions ISO [clothianidin co-treated with thiacloprid] results in increased expression of CES2 protein; [enilconazole co-treated with thiacloprid] results in increased expression of CES2 protein CTD PMID:32201337 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP thiacloprid results in increased activity of [NACHRA1 protein co-treated with CHRNB2 protein]; thiacloprid results in increased activity of [NACHRA8 protein co-treated with CHRNB2 protein] CTD PMID:16981889 PMID:25459289 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CPT1A mRNA CTD PMID:32736067 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cybb cytochrome b-245 beta chain increases expression ISO thiacloprid results in increased expression of CYBB mRNA CTD PMID:32201337 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity
affects expression
multiple interactions
increases expression
ISO thiacloprid results in increased activity of CYP19A1 protein
thiacloprid affects the expression of CYP19A1 mRNA
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione affects the reaction [thiacloprid affects the expression of CYP19A1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [thiacloprid affects the expression of CYP19A1 mRNA]
thiacloprid results in increased expression of CYP19A1 mRNA
CTD PMID:26464060 PMID:28750898 PMID:29701941 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO thiacloprid results in increased expression of CYP1A1 mRNA; thiacloprid results in increased expression of CYP1A1 protein CTD PMID:21784029 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
multiple interactions
ISO thiacloprid results in increased expression of CYP1A2 mRNA; thiacloprid results in increased expression of CYP1A2 protein
[enilconazole co-treated with thiacloprid co-treated with clothianidin] results in increased expression of CYP1A2 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of CYP1A2 mRNA
CTD PMID:21784029 PMID:32201337 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of CYP2B10 mRNA; [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CYP2B10 mRNA CTD PMID:32736067 PMID:32745781 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
increases expression
ISO [clothianidin co-treated with thiacloprid] results in increased expression of CYP2B6 protein; [enilconazole co-treated with thiacloprid] results in increased expression of CYP2B6 protein; [enilconazole co-treated with thiacloprid] results in increased expression of CYP2B9 protein; [thiacloprid co-treated with enilconazole] results in increased expression of CYP2B6 mRNA
[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of CYP2B9 mRNA
thiacloprid results in increased expression of CYP2B6 mRNA
CTD PMID:32201337 PMID:32745781 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CYP2C55 mRNA CTD PMID:32736067 NCBI chr 1:258,074,797...258,139,176
Ensembl chr 1:258,074,860...258,139,176
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases expression
decreases expression
ISO thiacloprid results in increased expression of CYP2C19 mRNA
thiacloprid results in decreased expression of CYP2C19 protein
CTD PMID:32194361 PMID:32201337 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of CYP2C29 mRNA CTD PMID:32745781 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression
multiple interactions
ISO thiacloprid results in decreased expression of CYP2E1 mRNA
[clothianidin co-treated with thiacloprid] results in increased expression of CYP2E1 protein; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in decreased expression of CYP2E1 mRNA; [thiacloprid co-treated with clothianidin] results in decreased expression of CYP2E1 mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of CYP2E1 mRNA
CTD PMID:32201337 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 increases expression
multiple interactions
ISO thiacloprid results in increased expression of CYP3A4 mRNA; thiacloprid results in increased expression of CYP3A4 protein
[clothianidin co-treated with thiacloprid] results in increased expression of CYP3A4 protein; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in increased expression of CYP3A4 mRNA; [enilconazole co-treated with thiacloprid] results in increased expression of CYP3A4 protein; [thiacloprid co-treated with enilconazole] results in increased expression of CYP3A4 mRNA
CTD PMID:32201337 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression
multiple interactions
ISO thiacloprid results in increased expression of CYP3A5 mRNA
[enilconazole co-treated with thiacloprid] results in increased expression of CYP3A5 protein; [thiacloprid co-treated with clothianidin] results in increased expression of CYP3A5 mRNA
CTD PMID:32201337 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO thiacloprid results in decreased expression of CYP7A1 protein CTD PMID:32194361 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Dio1 iodothyronine deiodinase 1 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of DIO1 mRNA CTD PMID:32745781 NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of ECI1 mRNA CTD PMID:32736067 NCBI chr10:13,797,573...13,810,918
Ensembl chr10:13,797,562...13,810,913
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of GFAP protein CTD PMID:32736067 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression
multiple interactions
EXP thiacloprid results in increased expression of GPT protein
Polysaccharides inhibits the reaction [thiacloprid results in increased expression of GPT protein]
CTD PMID:31328355 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
decreases expression
EXP Polysaccharides inhibits the reaction [thiacloprid results in decreased expression of GPX1 mRNA] CTD PMID:28692354 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of HMGCS2 mRNA CTD PMID:32745781 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO NR1I3 protein affects the susceptibility to [2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with Thiophanate co-treated with thiacloprid co-treated with Ziram] CTD PMID:29950287 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of PDGFRB protein CTD PMID:32736067 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression ISO thiacloprid results in increased expression of POR mRNA CTD PMID:32201337 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SERPINE1 mRNA CTD PMID:32745781 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Slc16a2 solute carrier family 16 member 2 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SLC16A2 mRNA CTD PMID:32745781 NCBI chr  X:74,578,600...74,706,068
Ensembl chr  X:74,577,131...74,706,214
JBrowse link
G Slc22a1 solute carrier family 22 member 1 increases activity ISO thiacloprid metabolite results in increased activity of SLC22A1 protein; thiacloprid results in increased activity of SLC22A1 protein CTD PMID:31364238 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases activity ISO thiacloprid metabolite results in decreased activity of SLC22A2 protein; thiacloprid results in decreased activity of SLC22A2 protein CTD PMID:31364238 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc22a8 solute carrier family 22 member 8 decreases activity ISO thiacloprid metabolite results in decreased activity of SLC22A8 protein; thiacloprid results in decreased activity of SLC22A8 protein CTD PMID:31364238 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
decreases expression
EXP Polysaccharides inhibits the reaction [thiacloprid results in decreased expression of SOD1 mRNA] CTD PMID:28692354 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SULT1B1 mRNA CTD PMID:32745781 NCBI chr14:22,142,412...22,155,246
Ensembl chr14:22,142,364...22,155,231
JBrowse link
G Thrsp thyroid hormone responsive multiple interactions ISO [2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of THRSP mRNA; [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in decreased expression of THRSP mRNA; Dietary Fats inhibits the reaction [[2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of THRSP mRNA] CTD PMID:32745781 NCBI chr 1:162,381,251...162,385,575
Ensembl chr 1:162,381,253...162,385,575
JBrowse link
zopiclone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases metabolic processing ISO CYP2C8 protein results in increased metabolism of zopiclone CTD PMID:12464242 NCBI chr 1:147,236,480...147,307,988 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19771
    chemical entity 19771
      molecular entity 19770
        polyatomic entity 19688
          heteroatomic molecular entity 19619
            halide 18075
              organohalogen compound 17843
                organochlorine compound 17641
                  chloropyridine 1023
                    monochloropyridine 139
                      2-chloropyridine + 139
                      6-chloro-3-hydroxypyridine-2,5-dione 0
                      acetamiprid + 42
                      betrixaban 0
                      fluopicolide 0
                      fluopimomide 0
                      flupyradifurone 0
                      imidacloprid + 85
                      imidacloprid-urea 0
                      nitenpyram + 4
                      thiacloprid + 40
                      thiacloprid-amide 0
                      zopiclone + 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19771
    subatomic particle 19770
      composite particle 19770
        hadron 19770
          baryon 19770
            nucleon 19770
              atomic nucleus 19770
                atom 19770
                  main group element atom 19658
                    p-block element atom 19658
                      carbon group element atom 19574
                        carbon atom 19564
                          organic molecular entity 19564
                            organic molecule 19497
                              organic cyclic compound 19321
                                organic heterocyclic compound 18512
                                  organic heteromonocyclic compound 16988
                                    pyridines 8438
                                      chloropyridine 1023
                                        monochloropyridine 139
                                          2-chloropyridine + 139
                                          6-chloro-3-hydroxypyridine-2,5-dione 0
                                          acetamiprid + 42
                                          betrixaban 0
                                          fluopicolide 0
                                          fluopimomide 0
                                          flupyradifurone 0
                                          imidacloprid + 85
                                          imidacloprid-urea 0
                                          nitenpyram + 4
                                          thiacloprid + 40
                                          thiacloprid-amide 0
                                          zopiclone + 1
paths to the root