Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2-diethylamino-6-methylpyrimidin-4(1H)-one
go back to main search page
Accession:CHEBI:38844 term browser browse the term
Definition:A pyrimidone that has formula C9H15N3O.
Synonyms:related_synonym: 2-(Diethylamino)-6-methyl-1H-pyrimidin-4-one;   Formula=C9H15N3O;   InChI=1S/C9H15N3O/c1-4-12(5-2)9-10-7(3)6-8(13)11-9/h6H,4-5H2,1-3H3,(H,10,11,13);   InChIKey=NQCPECCCWDWTJJ-UHFFFAOYSA-N;   SMILES=CCN(CC)c1nc(=O)cc(C)[nH]1
 xref: Beilstein:642602;   CAS:42487-72-9


show annotations for term's descendants           Sort by:
pirimiphos-methyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO pirimiphos methyl results in decreased activity of ACHE protein CTD PMID:8658539 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Anpep alanyl aminopeptidase, membrane decreases activity EXP pirimiphos methyl results in decreased activity of ANPEP protein CTD PMID:9204212 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789 		JBrowse link
G Ar androgen receptor multiple interactions ISO pirimiphos methyl inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA] CTD PMID:21310686 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Ctsc cathepsin C decreases activity
increases activity		 EXP pirimiphos methyl results in decreased activity of CTSC protein
pirimiphos methyl results in increased activity of CTSC protein		 CTD PMID:9204212 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387 		JBrowse link
G Ctsd cathepsin D decreases activity
increases activity		 EXP pirimiphos methyl results in decreased activity of CTSD protein
pirimiphos methyl results in increased activity of CTSD protein		 CTD PMID:9204212 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Ctsl cathepsin L increases activity EXP pirimiphos methyl results in increased activity of CTSL protein CTD PMID:9204212 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Dpp6 dipeptidyl peptidase like 6 decreases activity EXP pirimiphos methyl results in decreased activity of DPP6 protein CTD PMID:9204212 NCBI chr 4:7,589,386...8,508,666
Ensembl chr 4:7,591,009...8,508,532 		JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO pirimiphos methyl results in increased activity of ESR1 protein CTD PMID:15064155 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO pirimiphos methyl binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases activity ISO pirimiphos methyl results in increased activity of NR4A2 protein CTD PMID:20143881 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Park7 Parkinsonism associated deglycase decreases activity ISO pirimiphos methyl results in decreased activity of PARK7 protein CTD PMID:36842454 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Prep prolyl endopeptidase decreases activity EXP pirimiphos methyl results in decreased activity of PREP protein CTD PMID:9204212 NCBI chr20:48,556,211...48,653,165
Ensembl chr20:48,556,280...48,654,466 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [pirimiphos methyl binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2 CTD PMID:26359731 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rnpep arginyl aminopeptidase decreases activity EXP pirimiphos methyl results in decreased activity of RNPEP protein CTD PMID:9204212 NCBI chr13:46,699,458...46,717,829
Ensembl chr13:46,699,463...46,717,998 		JBrowse link
G Tpp1 tripeptidyl peptidase 1 decreases activity EXP pirimiphos methyl results in decreased activity of TPP1 protein CTD PMID:9204212 NCBI chr 1:160,097,984...160,104,108
Ensembl chr 1:160,096,833...160,104,129 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    role 19839
      application 19703
        NMR chemical shift reference compound 18081
          ammonia 17860
            organic amino compound 17860
              aromatic amine 15475
                aminopyrimidine 2023
                  2-diethylamino-6-methylpyrimidin-4(1H)-one 15
                    pirimiphos-methyl 15
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    main group molecular entity 19806
                      s-block molecular entity 19641
                        hydrogen molecular entity 19622
                          hydrides 19150
                            inorganic hydride 18152
                              pnictogen hydride 18164
                                nitrogen hydride 18055
                                  azane 17882
                                    ammonia 17860
                                      organic amino compound 17860
                                        aromatic amine 15475
                                          aminopyrimidine 2023
                                            2-diethylamino-6-methylpyrimidin-4(1H)-one 15
                                              pirimiphos-methyl 15
paths to the root