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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:picloram
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Accession:CHEBI:34922 term browser browse the term
Definition:A pyridinemonocarboxylic acid that is pyridine-2-carboxylic acid which is substituted by a chloro group at positions 3,5 and 6, and by an amino group at position 4. It is a systemic herbicide used to control deeply rooted herbaceous weeds and woody plants in rights-of-way, forestry, range lands, pastures, and small grain crops.
Synonyms:related_synonym: 3,5,6-trichloro-4-aminopicolinic acid;   4-Amino-3,5,6-trichloropyridine-2-carboxylic acid;   4-amino-3,5,6-trichloro-2-picolinic acid;   4-amino-3,5,6-trichloro-2-pyridinecarboxylic acid;   4-amino-3,5,6-trichloropicolinic acid;   Access;   Amdon;   Borolin;   Formula=C6H3Cl3N2O2;   Grazon;   InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13);   InChIKey=NQQVFXUMIDALNH-UHFFFAOYSA-N;   K-Pin;   Pathway;   SMILES=C1(=C(C(C(=O)O)=NC(=C1Cl)Cl)Cl)N;   Tordon;   picloram acid;   piclorame
 xref: AGR:IND606190450;   Beilstein:0479075;   CAS:1918-02-1;   KEGG:C14310
 xref_mesh: MESH:D010846
 xref: PMID:11319026;   PMID:11368227;   PMID:12128102;   PMID:16920877;   PMID:24737019;   PMID:28281061;   PMID:28819832;   PMID:29948674;   PMID:31055199;   PMID:31254607;   PMID:31382345;   PMID:31414816;   PMID:3567404;   PMID:5153743;   PPDB:525;   Pesticides:picloram;   Wikipedia:Picloram


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picloram term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cux1 cut-like homeobox 1 multiple interactions ISO [Herbicides results in increased abundance of Picloram] which affects the methylation of CUX1 gene CTD PMID:34516295 NCBI chr12:20,107,062...20,425,868
Ensembl chr12:20,107,311...20,425,866 		JBrowse link
G Foxo1 forkhead box O1 decreases expression
multiple interactions		 ISO Picloram results in decreased expression of FOXO1 mRNA
arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of FOXO1 mRNA]		 CTD PMID:21318024 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 decreases expression
multiple interactions		 ISO Picloram results in decreased expression of GRIN1 mRNA
arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of GRIN1 mRNA]		 CTD PMID:21318024 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions ISO [Herbicides results in increased abundance of Picloram] which affects the methylation of HTR2A gene CTD PMID:34516295 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Mettl15 methyltransferase 15, mitochondrial 12S rRNA N4-cytidine multiple interactions ISO [Herbicides results in increased abundance of Picloram] which affects the methylation of METTL15 gene CTD PMID:34516295 NCBI chr 3:95,586,855...95,764,392
Ensembl chr 3:95,586,850...95,764,397 		JBrowse link
G Msra methionine sulfoxide reductase A multiple interactions ISO [Herbicides results in increased abundance of Picloram] which affects the methylation of MSRA gene CTD PMID:34516295 NCBI chr15:38,363,459...38,677,406
Ensembl chr15:38,351,445...38,676,585 		JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 multiple interactions
decreases expression		 ISO arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of ATP6 mRNA] CTD PMID:21318024 NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599 		JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I decreases expression
multiple interactions		 ISO Picloram results in decreased expression of COX1 mRNA
arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of COX1 mRNA]		 CTD PMID:21318024 NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867 		JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b multiple interactions
decreases expression		 ISO arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of CYTB mRNA] CTD PMID:21318024 NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278 		JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 multiple interactions
decreases expression		 ISO arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of ND1 mRNA] CTD PMID:21318024 NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Picloram results in increased expression of PPARGC1A mRNA CTD PMID:21318024 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions
decreases expression		 ISO arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX1 mRNA] CTD PMID:21318024 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Prdx2 peroxiredoxin 2 multiple interactions
decreases expression		 ISO arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX2 mRNA] CTD PMID:21318024 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Prdx3 peroxiredoxin 3 multiple interactions
decreases expression		 ISO arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX3 mRNA] CTD PMID:21318024 NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111 		JBrowse link
G Prdx4 peroxiredoxin 4 multiple interactions
decreases expression		 ISO arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX4 mRNA] CTD PMID:21318024 NCBI chr  X:40,026,762...40,044,066
Ensembl chr  X:40,026,651...40,044,066 		JBrowse link
G Prdx5 peroxiredoxin 5 decreases expression
multiple interactions		 ISO Picloram results in decreased expression of PRDX5 mRNA
arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX5 mRNA]		 CTD PMID:21318024 NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268 		JBrowse link
G Prdx6 peroxiredoxin 6 multiple interactions
decreases expression		 ISO arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX6 mRNA] CTD PMID:21318024 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355 		JBrowse link
G Tbc1d32 TBC1 domain family, member 32 multiple interactions ISO [Herbicides results in increased abundance of Picloram] which affects the methylation of TBC1D32 gene CTD PMID:34516295 NCBI chr20:35,359,865...35,590,992
Ensembl chr20:35,359,863...35,590,415 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    role 19839
      application 19703
        pesticide 18059
          herbicide 16022
            picloram 18
              picloram-methyl 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    p-block element atom 19806
                      carbon group element atom 19746
                        carbon atom 19743
                          organic molecular entity 19743
                            heteroorganic entity 19502
                              organochalcogen compound 19264
                                organooxygen compound 19180
                                  carbon oxoacid 18666
                                    carboxylic acid 18663
                                      monocarboxylic acid 18013
                                        pyridinemonocarboxylic acid 424
                                          picolinic acid 40
                                            picloram 18
                                              picloram-methyl 0
paths to the root