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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71007
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prdx5
Name: peroxiredoxin 5
Acc ID: CHEBI:34922
Term: picloram
Definition: A pyridinemonocarboxylic acid that is pyridine-2-carboxylic acid which is substituted by a chloro group at positions 3,5 and 6, and by an amino group at position 4. It is a systemic herbicide used to control deeply rooted herbaceous weeds and woody plants in rights-of-way, forestry, range lands, pastures, and small grain crops.
Chemical ID: MESH:D010846
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prdx5decreases expressionISOPrdx5 (Mus musculus)6480464CTDPicloram results in decreased expression of PRDX5 mRNAPMID:21318024
Prdx5multiple interactionsISOPrdx5 (Mus musculus)6480464CTDarginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX5 mRNA]PMID:21318024
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