CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: butachlor
Accession: CHEBI:3230
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Definition: An aromatic amide that is 2-choro-N-(2,6-diethylphenyl)acetamide in which the amide nitrogen has been replaced by a butoxymethyl group.
Synonyms: exact_synonym: N-(butoxymethyl)-2-chloro-N-(2,6-diethylphenyl)acetamide
related_synonym: 2',6'-Diethyl-N-butoxymethyl-2-chloroacetanilide; 2',6'-Diethyl-N-butoxymethyl-alpha-chloroacetanilide; 2-Chloro-2',6'-diethyl-N-(butoxymethyl)acetanilide; Formula=C17H26ClNO2; InChI=1S/C17H26ClNO2/c1-4-7-11-21-13-19(16(20)12-18)17-14(5-2)9-8-10-15(17)6-3/h8-10H,4-7,11-13H2,1-3H3; InChIKey=HKPHPIREJKHECO-UHFFFAOYSA-N; N-(Butoxymethyl)-2-chloro-2',6'-diethylacetanilide; N-Butoxymethyl-alpha-chloro-2',6'-diethylacetanilide; SMILES=C1=CC=C(C(=C1CC)N(COCCCC)C(CCl)=O)CC
xref: AGR:IND601190844; CAS:23184-66-9; KEGG:C10931
xref_mesh: MESH:C054409
xref: MetaCyc:CPD-18941; PMID:20183093; PMID:25097380; PMID:25378033; PMID:25528421; PMID:25708297; PMID:25763539; PMID:26027538; PMID:26368393; PMID:26372161; PMID:26461443; PMID:26946506; PMID:26971167; PMID:27071456; PMID:27182978; PMID:27419617; PMID:27480594; PMID:27514993; PMID:27522569; PMID:27579872; PMID:27943158; PMID:27974272; PMID:27987462; PMID:28045224; PMID:28190210; PPDB:101; Reaxys:2873811
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Alb
albumin
increases expression
ISO
butachlor results in increased expression of ALB protein
CTD
PMID:34351278
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Apaf1
apoptotic peptidase activating factor 1
decreases expression
ISO
butachlor results in decreased expression of APAF1 mRNA
CTD
PMID:34351278
NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
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Ar
androgen receptor
increases activity
ISO
butachlor results in increased activity of AR protein
CTD
PMID:20143881
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Atg5
autophagy related 5
decreases expression increases expression
ISO
butachlor results in decreased expression of ATG5 mRNA butachlor results in increased expression of ATG5 protein
CTD
PMID:34351278
NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
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Casp3
caspase 3
decreases expression
ISO
butachlor results in decreased expression of CASP3 mRNA
CTD
PMID:34351278
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp9
caspase 9
decreases expression
ISO
butachlor results in decreased expression of CASP9 mRNA
CTD
PMID:34351278
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Cycs
cytochrome c, somatic
decreases expression
ISO
butachlor results in decreased expression of CYCS mRNA
CTD
PMID:34351278
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
increases metabolic processing
ISO
CYP2B6 protein results in increased metabolism of butachlor
CTD
PMID:11133395
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
increases metabolic processing
ISO
CYP3A4 protein results in increased metabolism of butachlor
CTD
PMID:11133395
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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Dio1
iodothyronine deiodinase 1
decreases activity
ISO
butachlor results in decreased activity of DIO1 protein
CTD
PMID:29228274
NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
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Il10
interleukin 10
decreases expression
ISO
butachlor results in decreased expression of IL10 mRNA
CTD
PMID:34351278
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Map1lc3b
microtubule-associated protein 1 light chain 3 beta
increases expression
ISO
butachlor results in increased expression of MAP1LC3B protein
CTD
PMID:34351278
NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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Mtor
mechanistic target of rapamycin kinase
decreases expression
ISO
butachlor results in decreased expression of MTOR mRNA
CTD
PMID:34351278
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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Nr1h4
nuclear receptor subfamily 1, group H, member 4
increases activity
ISO
butachlor results in increased activity of NR1H4 protein
CTD
PMID:20143881
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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Nr3c1
nuclear receptor subfamily 3, group C, member 1
increases activity
ISO
butachlor results in increased activity of NR3C1 protein
CTD
PMID:20143881
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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Sqstm1
sequestosome 1
decreases expression
ISO
butachlor results in decreased expression of SQSTM1 mRNA; butachlor results in decreased expression of SQSTM1 protein
CTD
PMID:34351278
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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Thrb
thyroid hormone receptor beta
affects binding
ISO
butachlor binds to THRB protein
CTD
PMID:28973306
NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
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Tnf
tumor necrosis factor
decreases expression
ISO
butachlor results in decreased expression of TNF mRNA
CTD
PMID:34351278
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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