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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:lead(II) chloride
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Accession:CHEBI:88212 term browser browse the term
Definition:An inorganic chloride consisting of two chlorine atoms covalently bound to a central lead atom.
Synonyms:exact_synonym: dichloro-lambda(2)-plumbane;   lead(2+) dichloride
 related_synonym: Formula=Cl2Pb;   InChI=1S/2ClH.Pb/h2*1H;/q;;+2/p-2;   InChIKey=HWSZZLVAJGOAAY-UHFFFAOYSA-L;   Lead dichloride;   Lead(2+) chloride;   PbCl2;   Plumbous chloride;   SMILES=[Pb](Cl)Cl;   lead chloride
 xref: CAS:7758-95-4
 xref_mesh: MESH:C029891
 xref: PMID:11345460;   Reaxys:3902843;   Reaxys:8128172;   Wikipedia:Lead(II)_chloride


show annotations for term's descendants           Sort by:
lead(II) chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Yt blood group) multiple interactions ISO [lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased activity of ACHE protein; [zinc chloride co-treated with Sodium Selenite] inhibits the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased activity of ACHE protein] CTD PMID:36646412 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G ACSL4 acyl-CoA synthetase long chain family member 4 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of ACSL4 mRNA CTD PMID:18654764 NCBI chr  X:109,641,335...109,733,257
Ensembl chr  X:109,624,244...109,733,403 		JBrowse link
G ACTB actin beta decreases expression EXP lead chloride results in decreased expression of ACTB protein CTD PMID:24419708 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902 		JBrowse link
G ADK adenosine kinase multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of ADK mRNA CTD PMID:18654764 NCBI chr10:74,151,221...74,709,290
Ensembl chr10:74,151,202...74,709,963 		JBrowse link
G AKR1B10 aldo-keto reductase family 1 member B10 multiple interactions
increases expression		 EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of AKR1B10 mRNA
lead chloride results in increased expression of AKR1B10 mRNA		 CTD PMID:18654764 NCBI chr 7:134,527,567...134,541,412
Ensembl chr 7:134,527,567...134,541,412 		JBrowse link
G AKR1C1 aldo-keto reductase family 1 member C1 multiple interactions
increases expression		 EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of AKR1C1 mRNA
lead chloride results in increased expression of AKR1C1 mRNA		 CTD PMID:18654764 NCBI chr10:4,963,415...4,983,283
Ensembl chr10:4,963,253...4,983,283 		JBrowse link
G AKR1C2 aldo-keto reductase family 1 member C2 multiple interactions
increases expression		 EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of AKR1C2 mRNA
lead chloride results in increased expression of AKR1C2 mRNA		 CTD PMID:18654764 NCBI chr10:4,987,775...5,018,000
Ensembl chr10:4,987,775...5,018,031 		JBrowse link
G ANXA1 annexin A1 increases expression EXP lead chloride results in increased expression of ANXA1 protein CTD PMID:24419708 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393 		JBrowse link
G ATF4 activating transcription factor 4 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] affects the expression of ATF4 mRNA CTD PMID:18654764 NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP lead chloride results in decreased expression of BCL2 protein CTD PMID:24419708 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BHLHE40 basic helix-loop-helix family member e40 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of BHLHE40 mRNA CTD PMID:18654764 NCBI chr 3:4,979,437...4,985,323
Ensembl chr 3:4,979,437...4,985,323 		JBrowse link
G CALD1 caldesmon 1 decreases expression EXP lead chloride results in decreased expression of CALD1 protein CTD PMID:24419708 NCBI chr 7:134,745,467...134,970,729
Ensembl chr 7:134,744,252...134,970,729 		JBrowse link
G CASP3 caspase 3 increases cleavage
multiple interactions		 EXP
ISO		 lead chloride results in increased cleavage of CASP3 protein
[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of CASP3 protein; [zinc chloride co-treated with lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of CASP3 protein
[[lead chloride results in increased abundance of Lead] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of CASP3 protein; [[lead chloride results in increased abundance of Lead] which co-treated with methylmercuric chloride] results in increased expression of CASP3 protein		 CTD PMID:24419708 PMID:32179164 PMID:36646412 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP9 caspase 9 increases cleavage EXP lead chloride results in increased cleavage of CASP9 protein CTD PMID:24419708 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase multiple interactions ISO [[lead chloride results in increased abundance of Lead] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of CAT protein; [[lead chloride results in increased abundance of Lead] which co-treated with methylmercuric chloride] results in increased expression of CAT protein
[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in decreased activity of CAT protein; [zinc chloride co-treated with Sodium Selenite] inhibits the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in decreased activity of CAT protein]; Sodium Selenite inhibits the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in decreased activity of CAT protein]		 CTD PMID:32179164 PMID:36646412 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCL3 C-C motif chemokine ligand 3 multiple interactions EXP lead chloride promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL3 protein] CTD PMID:36416909 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 increases secretion EXP lead chloride results in increased secretion of CCL5 protein CTD PMID:16099135 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCNA1 cyclin A1 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in decreased expression of CCNA1 mRNA CTD PMID:18654764 NCBI chr13:36,431,517...36,442,870
Ensembl chr13:36,431,520...36,442,870 		JBrowse link
G CCT2 chaperonin containing TCP1 subunit 2 decreases expression EXP lead chloride results in decreased expression of CCT2 protein CTD PMID:24419708 NCBI chr12:69,585,459...69,601,570
Ensembl chr12:69,585,426...69,601,570 		JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 decreases expression EXP lead chloride results in decreased expression of CCT5 protein CTD PMID:24419708 NCBI chr 5:10,249,921...10,266,412
Ensembl chr 5:10,249,929...10,266,389 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] affects the expression of CREB1 mRNA CTD PMID:18654764 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases secretion
multiple interactions		 EXP lead chloride results in increased secretion of CXCL8 protein
lead chloride promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CXCL8 protein]		 CTD PMID:16099135 PMID:36416909 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases expression ISO lead chloride results in increased expression of CYP1A1 mRNA CTD PMID:23503628 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP2A6 cytochrome P450 family 2 subfamily A member 6 multiple interactions
increases expression		 ISO [lead chloride affects the localization of NFE2L2 protein] promotes the reaction [NFE2L2 protein binds to CYP2A5 promoter]; NFE2L2 protein affects the reaction [lead chloride results in increased expression of CYP2A5 mRNA] CTD PMID:20402460 NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447 		JBrowse link
G DDAH2 DDAH family member 2, ADMA-independent increases expression EXP lead chloride results in increased expression of DDAH2 protein CTD PMID:24419708 NCBI chr 6:31,727,040...31,730,263
Ensembl chr 6:31,727,038...31,730,617 		JBrowse link
G EEA1 early endosome antigen 1 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of EEA1 mRNA CTD PMID:18654764 NCBI chr12:92,770,637...92,929,295
Ensembl chr12:92,770,637...92,929,331 		JBrowse link
G EEF1B2 eukaryotic translation elongation factor 1 beta 2 increases expression EXP lead chloride results in increased expression of EEF1B2 protein CTD PMID:24419708 NCBI chr 2:206,159,609...206,162,928
Ensembl chr 2:206,159,585...206,162,928 		JBrowse link
G EEF1D eukaryotic translation elongation factor 1 delta decreases expression EXP lead chloride results in decreased expression of EEF1D protein CTD PMID:24419708 NCBI chr 8:143,579,728...143,597,415
Ensembl chr 8:143,579,697...143,599,541 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation EXP lead chloride results in increased phosphorylation of EIF2S1 protein CTD PMID:25410796 NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516 		JBrowse link
G ELK1 ETS transcription factor ELK1 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] affects the expression of ELK1 mRNA CTD PMID:18654764 NCBI chr  X:47,635,520...47,650,604
Ensembl chr  X:47,635,521...47,650,604 		JBrowse link
G ENO1 enolase 1 increases expression EXP lead chloride results in increased expression of ENO1 protein CTD PMID:24419708 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190 		JBrowse link
G ERG28 ergosterol biosynthesis 28 homolog multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of ERG28 mRNA CTD PMID:18654764 NCBI chr14:75,649,791...75,660,876
Ensembl chr14:75,649,791...75,660,876 		JBrowse link
G ESR1 estrogen receptor 1 affects response to substance
increases activity
decreases expression
multiple interactions		 EXP ESR1 protein affects the susceptibility to lead chloride
lead chloride results in increased activity of ESR1 protein
lead chloride results in decreased expression of ESR1 mRNA; lead chloride results in decreased expression of ESR1 protein
Estradiol promotes the reaction [lead chloride results in decreased expression of ESR1 mRNA]; Estradiol promotes the reaction [lead chloride results in decreased expression of ESR1 protein]; lead chloride inhibits the reaction [Estradiol binds to ESR1 protein]; lead chloride promotes the reaction [Estradiol results in decreased expression of ESR1 protein]		 CTD PMID:12746304 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G EXOC5 exocyst complex component 5 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of EXOC5 mRNA CTD PMID:18654764 NCBI chr14:57,200,507...57,268,905
Ensembl chr14:57,200,507...57,268,905 		JBrowse link
G F2R coagulation factor II thrombin receptor multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of F2R mRNA CTD PMID:18654764 NCBI chr 5:76,716,126...76,735,770
Ensembl chr 5:76,716,126...76,735,770 		JBrowse link
G GABRD gamma-aminobutyric acid type A receptor subunit delta increases expression ISO lead chloride results in increased expression of GABRD mRNA CTD PMID:19651682 NCBI chr 1:2,019,345...2,030,758
Ensembl chr 1:2,019,329...2,030,758 		JBrowse link
G GAS1 growth arrest specific 1 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in decreased expression of GAS1 mRNA CTD PMID:18654764 NCBI chr 9:86,944,362...86,947,506
Ensembl chr 9:86,944,362...86,947,506 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit multiple interactions
decreases expression
increases expression		 EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of GCLC mRNA
lead chloride results in decreased expression of GCLC protein
lead chloride results in increased expression of GCLC mRNA		 CTD PMID:18654764 PMID:30359721 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970 		JBrowse link
G GFAP glial fibrillary acidic protein decreases expression ISO lead chloride results in decreased expression of GFAP mRNA CTD PMID:19651682 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937 		JBrowse link
G GM2A ganglioside GM2 activator multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of GM2A mRNA CTD PMID:18654764 NCBI chr 5:151,253,185...151,270,440
Ensembl chr 5:151,212,150...151,270,440 		JBrowse link
G GNA13 G protein subunit alpha 13 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of GNA13 mRNA CTD PMID:18654764 NCBI chr17:65,009,289...65,056,740
Ensembl chr17:65,009,289...65,056,740 		JBrowse link
G GPNMB glycoprotein nmb multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of GPNMB mRNA CTD PMID:18654764 NCBI chr 7:23,246,775...23,275,108
Ensembl chr 7:23,235,967...23,275,108 		JBrowse link
G GPX2 glutathione peroxidase 2 multiple interactions
increases expression		 EXP
ISO		 [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of GPX2 mRNA
lead chloride results in increased expression of GPX2 mRNA		 CTD PMID:18654764 PMID:23503628 NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 increases expression ISO lead chloride results in increased expression of GRIN1 mRNA CTD PMID:19651682 NCBI chr 9:137,139,154...137,168,756
Ensembl chr 9:137,138,346...137,168,756 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 decreases expression EXP lead chloride results in decreased expression of GSTM1 protein CTD PMID:30359721 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G HEG1 heart development protein with EGF like domains 1 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of HEG1 mRNA CTD PMID:18654764 NCBI chr 3:124,965,710...125,055,997
Ensembl chr 3:124,965,710...125,055,997 		JBrowse link
G HIC1 HIC ZBTB transcriptional repressor 1 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] affects the expression of HIC1 mRNA CTD PMID:18654764 NCBI chr17:2,055,103...2,063,241
Ensembl chr17:2,054,154...2,063,241 		JBrowse link
G HMBS hydroxymethylbilane synthase decreases activity EXP
ISO		 lead chloride results in decreased activity of HMBS protein
Lead Chloride decreases activity of purified Hmbs protein		 CTD
RGD		 PMID:10416826 PMID:994723 RGD:25440497 NCBI chr11:119,084,881...119,093,549
Ensembl chr11:119,084,866...119,093,834 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of HMGCR mRNA CTD PMID:18654764 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of HMGCS1 mRNA CTD PMID:18654764 NCBI chr 5:43,287,470...43,313,412
Ensembl chr 5:43,287,470...43,313,512 		JBrowse link
G HMOX1 heme oxygenase 1 decreases expression
multiple interactions
increases expression		 ISO lead chloride results in decreased expression of HMOX1 mRNA
[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in decreased expression of HMOX1 protein; [zinc chloride co-treated with Sodium Selenite] inhibits the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in decreased expression of HMOX1 protein]; Sodium Selenite inhibits the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in decreased expression of HMOX1 protein]
lead chloride results in increased expression of HMOX1 mRNA		 CTD PMID:20402460 PMID:23503628 PMID:23916686 PMID:36646412 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HNRNPD heterogeneous nuclear ribonucleoprotein D multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in decreased expression of HNRNPD mRNA CTD PMID:18654764 NCBI chr 4:82,352,498...82,373,991
Ensembl chr 4:82,352,498...82,374,503 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 affects localization
increases expression
decreases expression		 ISO
EXP		 lead chloride affects the localization of HSPA5 protein
lead chloride results in increased expression of HSPA5 protein
lead chloride results in decreased expression of HSPA5 protein		 CTD PMID:19720107 PMID:21073006 PMID:24419708 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 decreases expression EXP lead chloride results in decreased expression of HSPA9 protein CTD PMID:24419708 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,675 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 increases expression EXP lead chloride results in increased expression of HSPB1 protein CTD PMID:24419708 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 decreases expression EXP lead chloride results in decreased expression of HSPD1 protein CTD PMID:24419708 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G IFNG interferon gamma decreases expression
multiple interactions		 EXP
ISO		 lead chloride results in decreased expression of IFNG protein
lead chloride results in decreased expression of IFNG mRNA
[lead chloride results in increased abundance of Lead] which results in increased expression of IFNG protein; decabromobiphenyl ether promotes the reaction [[lead chloride results in increased abundance of Lead] which results in increased expression of IFNG protein]; lead chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]]; lead chloride inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased chemical synthesis of Nitric Oxide]		 CTD PMID:8975779 PMID:15843504 PMID:23503628 PMID:30836164 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL10 interleukin 10 multiple interactions ISO [lead chloride results in increased abundance of Lead] promotes the reaction [decabromobiphenyl ether results in increased expression of IL10 protein]; [lead chloride results in increased abundance of Lead] which results in increased expression of IL10 protein; decabromobiphenyl ether promotes the reaction [[lead chloride results in increased abundance of Lead] which results in increased expression of IL10 protein] CTD PMID:30836164 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL12B interleukin 12B multiple interactions EXP lead chloride inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein] CTD PMID:36416909 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863 		JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in decreased expression of IL13RA2 mRNA CTD PMID:18654764 NCBI chr  X:115,003,982...115,017,616
Ensembl chr  X:115,003,975...115,019,977 		JBrowse link
G IL17A interleukin 17A multiple interactions ISO [lead chloride results in increased abundance of Lead] promotes the reaction [decabromobiphenyl ether results in increased expression of IL17A protein]; [lead chloride results in increased abundance of Lead] which results in increased expression of IL17A protein; decabromobiphenyl ether promotes the reaction [[lead chloride results in increased abundance of Lead] which results in increased expression of IL17A protein] CTD PMID:30836164 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL1B interleukin 1 beta decreases expression EXP
ISO		 lead chloride results in decreased expression of IL1B protein
lead chloride results in decreased expression of IL1B mRNA		 CTD PMID:15843504 PMID:23503628 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL2 interleukin 2 decreases expression EXP lead chloride results in decreased expression of IL2 protein CTD PMID:15183152 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IL4 interleukin 4 multiple interactions ISO [lead chloride results in increased abundance of Lead] which results in increased expression of IL4 protein; decabromobiphenyl ether promotes the reaction [[lead chloride results in increased abundance of Lead] which results in increased expression of IL4 protein] CTD PMID:30836164 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO [lead chloride results in increased abundance of Lead] which results in increased expression of IL6 protein; decabromobiphenyl ether promotes the reaction [[lead chloride results in increased abundance of Lead] which results in increased expression of IL6 protein]
[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of IL6 protein; Sodium Selenite promotes the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of IL6 protein]; zinc chloride inhibits the reaction [Sodium Selenite promotes the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of IL6 protein]]		 CTD PMID:30836164 PMID:36646412 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INSIG1 insulin induced gene 1 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of INSIG1 mRNA CTD PMID:18654764 NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235 		JBrowse link
G KCNS3 potassium voltage-gated channel modifier subfamily S member 3 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of KCNS3 mRNA CTD PMID:18654764 NCBI chr 2:17,877,847...17,932,958
Ensembl chr 2:17,877,847...18,361,616 		JBrowse link
G KLHL24 kelch like family member 24 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of KLHL24 mRNA CTD PMID:18654764 NCBI chr 3:183,635,623...183,684,519
Ensembl chr 3:183,635,610...183,684,519 		JBrowse link
G KLHL7 kelch like family member 7 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of KLHL7 mRNA CTD PMID:18654764 NCBI chr 7:23,105,785...23,177,914
Ensembl chr 7:23,105,758...23,177,914 		JBrowse link
G LAMP3 lysosomal associated membrane protein 3 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in decreased expression of LAMP3 mRNA CTD PMID:18654764 NCBI chr 3:183,122,215...183,163,813
Ensembl chr 3:183,122,215...183,163,839 		JBrowse link
G LYZ lysozyme decreases expression EXP lead chloride results in decreased expression of LYZ protein CTD PMID:24419708 NCBI chr12:69,348,381...69,354,234
Ensembl chr12:69,348,381...69,354,234 		JBrowse link
G MALAT1 metastasis associated lung adenocarcinoma transcript 1 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of MALAT1 mRNA CTD PMID:18654764 NCBI chr11:65,497,738...65,506,516
Ensembl chr11:65,497,640...65,508,073 		JBrowse link
G MAOA monoamine oxidase A multiple interactions ISO [[lead chloride results in increased abundance of Lead] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of MAOA protein CTD PMID:32179164 NCBI chr  X:43,655,006...43,746,817
Ensembl chr  X:43,654,907...43,746,817 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 increases expression EXP lead chloride results in increased expression of MAPK8 protein modified form CTD PMID:24419708 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 increases expression EXP lead chloride results in increased expression of MAPK9 protein modified form CTD PMID:24419708 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099 		JBrowse link
G MCU mitochondrial calcium uniporter decreases expression ISO lead chloride results in decreased expression of MCU protein CTD PMID:24881885 NCBI chr10:72,692,143...72,887,694
Ensembl chr10:72,692,143...72,887,694 		JBrowse link
G MT1A metallothionein 1A increases expression ISO lead chloride results in increased expression of MT1A mRNA CTD PMID:19720107 NCBI chr16:56,638,666...56,640,087
Ensembl chr16:56,638,666...56,640,087 		JBrowse link
G MT1X metallothionein 1X increases expression
multiple interactions		 ISO lead chloride results in increased expression of MT1 mRNA
[[lead chloride results in increased abundance of Lead] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of MT1 protein; [[lead chloride results in increased abundance of Lead] which co-treated with methylmercuric chloride] results in increased expression of MT1 protein		 CTD PMID:23503628 PMID:32179164 NCBI chr16:56,682,470...56,684,196
Ensembl chr16:56,682,470...56,684,196 		JBrowse link
G MT2A metallothionein 2A increases expression ISO lead chloride results in increased expression of MT2 mRNA CTD PMID:23503628 NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497 		JBrowse link
G MYL6 myosin light chain 6 increases expression EXP lead chloride results in increased expression of MYL6 protein CTD PMID:24419708 NCBI chr12:56,158,359...56,161,579
Ensembl chr12:56,158,346...56,163,496 		JBrowse link
G NCAM1 neural cell adhesion molecule 1 decreases expression ISO lead chloride results in decreased expression of NCAM1 mRNA; lead chloride results in decreased expression of NCAM1 protein; lead chloride results in decreased expression of NCAM1 protein modified form CTD PMID:18499259 NCBI chr11:112,961,420...113,278,436
Ensembl chr11:112,961,275...113,278,436 		JBrowse link
G NEDD4 NEDD4 E3 ubiquitin protein ligase multiple interactions ISO [[lead chloride results in increased abundance of Lead] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased expression of NEDD4 protein; [[lead chloride results in increased abundance of Lead] which co-treated with methylmercuric chloride] results in decreased expression of NEDD4 protein CTD PMID:32179164 NCBI chr15:55,826,917...55,993,612
Ensembl chr15:55,826,922...55,993,660 		JBrowse link
G NEFH neurofilament heavy chain increases expression ISO lead chloride results in increased expression of NEFH mRNA CTD PMID:19651682 NCBI chr22:29,480,218...29,491,390
Ensembl chr22:29,480,218...29,491,390 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions
decreases expression
affects localization		 ISO
EXP		 [lead chloride affects the localization of NFE2L2 protein] promotes the reaction [NFE2L2 protein binds to CYP2A5 promoter]; NFE2L2 protein affects the reaction [lead chloride results in increased expression of CYP2A5 mRNA]
[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of NFE2L2 protein; [Sodium Selenite co-treated with zinc chloride] inhibits the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of NFE2L2 protein]
lead chloride results in decreased expression of NFE2L2 protein		 CTD PMID:20402460 PMID:30359721 PMID:36646412 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NOS1 nitric oxide synthase 1 increases expression
decreases expression		 ISO
EXP		 lead chloride results in increased expression of NOS1 protein
lead chloride results in decreased expression of NOS1 mRNA; lead chloride results in decreased expression of NOS1 protein		 CTD PMID:24881885 PMID:25410796 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170 		JBrowse link
G NOS2 nitric oxide synthase 2 decreases expression
increases expression
multiple interactions		 ISO
EXP		 lead chloride results in decreased expression of NOS2 mRNA
lead chloride results in decreased expression of NOS2 mRNA; lead chloride results in decreased expression of NOS2 protein
lead chloride results in increased expression of NOS2 mRNA
lead chloride inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] promotes the reaction [NOS2 protein results in increased chemical synthesis of Nitric Oxide]]		 CTD PMID:8975779 PMID:23503628 PMID:23916686 PMID:25410796 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 decreases expression EXP lead chloride results in decreased expression of NOS3 mRNA; lead chloride results in decreased expression of NOS3 protein CTD PMID:25410796 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NOX4 NADPH oxidase 4 increases expression EXP lead chloride results in increased expression of NOX4 protein CTD PMID:30359721 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187 		JBrowse link
G PDE7A phosphodiesterase 7A multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of PDE7A mRNA CTD PMID:18654764 NCBI chr 8:65,714,334...65,842,064
Ensembl chr 8:65,714,334...65,842,322 		JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 decreases expression EXP lead chloride results in decreased expression of PDIA3 protein CTD PMID:24419708 NCBI chr15:43,746,438...43,773,278
Ensembl chr15:43,746,394...43,773,279 		JBrowse link
G PGR progesterone receptor multiple interactions
increases expression		 EXP Estradiol promotes the reaction [lead chloride results in increased expression of PGR mRNA]; Estradiol promotes the reaction [lead chloride results in increased expression of PGR protein]; fulvestrant inhibits the reaction [lead chloride results in increased expression of PGR mRNA]; fulvestrant inhibits the reaction [lead chloride results in increased expression of PGR protein]; lead chloride promotes the reaction [Estradiol results in increased expression of PGR mRNA]; lead chloride promotes the reaction [Estradiol results in increased expression of PGR protein]
lead chloride results in increased expression of PGR mRNA; lead chloride results in increased expression of PGR protein		 CTD PMID:12746304 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G PLA2G4A phospholipase A2 group IVA multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of PLA2G4A mRNA CTD PMID:18654764 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981 		JBrowse link
G PLIN3 perilipin 3 decreases expression EXP lead chloride results in decreased expression of PLIN3 protein CTD PMID:24419708 NCBI chr19:4,838,341...4,867,667
Ensembl chr19:4,838,341...4,867,694 		JBrowse link
G POU2F1 POU class 2 homeobox 1 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] affects the expression of POU2F1 mRNA CTD PMID:18654764 NCBI chr 1:167,220,885...167,427,345
Ensembl chr 1:167,220,876...167,427,345 		JBrowse link
G PTGR1 prostaglandin reductase 1 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of PTGR1 mRNA CTD PMID:18654764 NCBI chr 9:111,549,722...111,599,647
Ensembl chr 9:111,549,722...111,599,893 		JBrowse link
G RGCC regulator of cell cycle multiple interactions
increases expression		 EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of RGCC mRNA
lead chloride results in increased expression of RGCC mRNA		 CTD PMID:18654764 NCBI chr13:41,457,550...41,470,871
Ensembl chr13:41,457,550...41,470,871 		JBrowse link
G RNASE4 ribonuclease A family member 4 multiple interactions
increases expression		 EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of RNASE4 mRNA
lead chloride results in increased expression of RNASE4 mRNA		 CTD PMID:18654764 NCBI chr14:20,684,560...20,701,216
Ensembl chr14:20,684,560...20,701,216 		JBrowse link
G RUSC1-AS1 RUSC1 antisense RNA 1 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of RUSC1-AS1 mRNA CTD PMID:18654764 NCBI chr 1:155,316,854...155,324,176
Ensembl chr 1:155,316,863...155,324,176 		JBrowse link
G S100A11 S100 calcium binding protein A11 increases expression EXP lead chloride results in increased expression of S100A11 protein CTD PMID:24419708 NCBI chr 1:152,032,506...152,037,004
Ensembl chr 1:152,032,506...152,047,907 		JBrowse link
G SCAMP1 secretory carrier membrane protein 1 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of SCAMP1 mRNA CTD PMID:18654764 NCBI chr 5:78,360,617...78,480,739
Ensembl chr 5:78,360,611...78,480,739 		JBrowse link
G SEPTIN5 septin 5 multiple interactions ISO [[lead chloride results in increased abundance of Lead] which co-treated with methylmercuric chloride] results in decreased expression of SEPTIN5 protein CTD PMID:32179164 NCBI chr22:19,714,503...19,723,319
Ensembl chr22:19,714,503...19,724,224 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 increases expression ISO lead chloride results in increased expression of SLC11A2 mRNA CTD PMID:23503628 NCBI chr12:50,952,263...51,028,886
Ensembl chr12:50,979,401...51,028,566 		JBrowse link
G SLC22A8 solute carrier family 22 member 8 increases activity
multiple interactions		 EXP lead chloride results in increased activity of SLC22A8 protein
lead chloride promotes the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]		 CTD PMID:28629854 NCBI chr11:62,992,824...63,015,841
Ensembl chr11:62,989,154...63,015,841 		JBrowse link
G SLC6A6 solute carrier family 6 member 6 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of SLC6A6 mRNA CTD PMID:18654764 NCBI chr 3:14,402,576...14,489,349
Ensembl chr 3:14,402,576...14,489,349 		JBrowse link
G SNHG12 small nucleolar RNA host gene 12 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in decreased expression of SNHG12 mRNA CTD PMID:18654764 NCBI chr 1:28,578,538...28,582,983
Ensembl chr 1:28,578,538...28,583,132 		JBrowse link
G SNRNP70 small nuclear ribonucleoprotein U1 subunit 70 multiple interactions ISO [[lead chloride results in increased abundance of Lead] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of SNRNP70 protein; [[lead chloride results in increased abundance of Lead] which co-treated with methylmercuric chloride] results in increased expression of SNRNP70 protein CTD PMID:32179164 NCBI chr19:49,085,451...49,108,604
Ensembl chr19:49,085,419...49,108,605 		JBrowse link
G SOD1 superoxide dismutase 1 decreases expression
increases expression		 ISO lead chloride results in decreased expression of SOD1 mRNA
lead chloride results in increased expression of SOD1 mRNA		 CTD PMID:23503628 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SP1 Sp1 transcription factor multiple interactions ISO [[lead chloride results in increased abundance of Lead] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of SP1 protein; [[lead chloride results in increased abundance of Lead] which co-treated with methylmercuric chloride] results in increased expression of SP1 protein CTD PMID:32179164 NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446 		JBrowse link
G SQLE squalene epoxidase multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of SQLE mRNA CTD PMID:18654764 NCBI chr 8:124,998,505...125,022,283
Ensembl chr 8:124,998,497...125,022,283 		JBrowse link
G SRF serum response factor multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] affects the expression of SRF mRNA CTD PMID:18654764 NCBI chr 6:43,171,269...43,181,506
Ensembl chr 6:43,171,269...43,181,506 		JBrowse link
G SRY sex determining region Y multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] affects the expression of SRY mRNA CTD PMID:18654764 NCBI chr  Y:2,786,855...2,787,682
Ensembl chr  Y:2,786,855...2,787,682 		JBrowse link
G ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 decreases expression ISO lead chloride results in decreased expression of ST8SIA2 mRNA CTD PMID:18499259 NCBI chr15:92,393,881...92,468,728
Ensembl chr15:92,393,881...92,468,728 		JBrowse link
G ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 decreases expression ISO lead chloride results in decreased expression of ST8SIA4 mRNA CTD PMID:18499259 NCBI chr 5:100,806,933...100,903,282
Ensembl chr 5:100,806,933...100,903,282 		JBrowse link
G STK26 serine/threonine kinase 26 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of STK26 mRNA CTD PMID:18654764 NCBI chr  X:132,023,302...132,075,943
Ensembl chr  X:132,023,302...132,075,943 		JBrowse link
G TGFB1 transforming growth factor beta 1 decreases expression ISO lead chloride results in decreased expression of TGFB1 mRNA CTD PMID:23503628 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TKT transketolase increases expression EXP lead chloride results in increased expression of TKT mRNA CTD PMID:18654764 NCBI chr 3:53,224,712...53,256,022
Ensembl chr 3:53,224,712...53,256,052 		JBrowse link
G TMEM97 transmembrane protein 97 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of TMEM97 mRNA CTD PMID:18654764 NCBI chr17:28,319,200...28,328,685
Ensembl chr17:28,319,200...28,328,685 		JBrowse link
G TNF tumor necrosis factor decreases expression
multiple interactions		 EXP
ISO		 lead chloride results in decreased expression of TNF protein
[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of TNF protein; [Sodium Selenite co-treated with zinc chloride] affects the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of TNF protein]; Sodium Selenite affects the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of TNF protein]; zinc chloride inhibits the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of TNF protein]
lead chloride promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]
lead chloride results in decreased expression of TNF mRNA
[lead chloride results in increased abundance of Lead] promotes the reaction [decabromobiphenyl ether results in increased expression of TNF protein]; [lead chloride results in increased abundance of Lead] which results in increased expression of TNF protein; decabromobiphenyl ether promotes the reaction [[lead chloride results in increased abundance of Lead] which results in increased expression of TNF protein]; lead chloride inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased chemical synthesis of Nitric Oxide]		 CTD PMID:8975779 PMID:15843504 PMID:23503628 PMID:30836164 PMID:36416909 More... NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TSHB thyroid stimulating hormone subunit beta multiple interactions ISO [Hydrocarbons, Chlorinated co-treated with Cadmium Chloride co-treated with lead chloride] results in increased expression of TSHB protein CTD PMID:12011480 NCBI chr 1:115,029,826...115,034,309
Ensembl chr 1:115,029,826...115,034,302 		JBrowse link
G TSPAN7 tetraspanin 7 increases expression
multiple interactions		 EXP lead chloride results in increased expression of TSPAN7 mRNA
[cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of TSPAN7 mRNA		 CTD PMID:18654764 NCBI chr  X:38,561,542...38,688,918
Ensembl chr  X:38,561,542...38,688,920 		JBrowse link
G TUBB tubulin beta class I increases expression EXP lead chloride results in increased expression of TUBB protein CTD PMID:24419708 NCBI chr 6:30,720,352...30,725,422
Ensembl chr 6:30,717,435...30,725,538 		JBrowse link
G TUBB4B tubulin beta 4B class IVb increases expression EXP lead chloride results in increased expression of TUBB4B protein CTD PMID:24419708 NCBI chr 9:137,241,287...137,243,707
Ensembl chr 9:137,241,287...137,243,707 		JBrowse link
G TYMS thymidylate synthetase multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of TYMS mRNA CTD PMID:18654764 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578 		JBrowse link
G UBA1 ubiquitin like modifier activating enzyme 1 multiple interactions ISO [[lead chloride results in increased abundance of Lead] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of UBA1 protein; [[lead chloride results in increased abundance of Lead] which co-treated with methylmercuric chloride] results in increased expression of UBA1 protein CTD PMID:32179164 NCBI chr  X:47,190,847...47,215,128
Ensembl chr  X:47,190,861...47,215,128 		JBrowse link
G UCHL3 ubiquitin C-terminal hydrolase L3 multiple interactions ISO [[lead chloride results in increased abundance of Lead] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of UCHL3 protein; [[lead chloride results in increased abundance of Lead] which co-treated with methylmercuric chloride] results in increased expression of UCHL3 protein CTD PMID:32179164 NCBI chr13:75,549,502...75,606,020
Ensembl chr13:75,549,483...75,606,020 		JBrowse link
G UGDH UDP-glucose 6-dehydrogenase multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of UGDH mRNA CTD PMID:18654764 NCBI chr 4:39,498,755...39,527,439
Ensembl chr 4:39,498,755...39,528,311 		JBrowse link
G VCP valosin containing protein decreases expression EXP lead chloride results in decreased expression of VCP protein CTD PMID:24419708 NCBI chr 9:35,056,064...35,072,625
Ensembl chr 9:35,053,928...35,072,668 		JBrowse link
G VIM vimentin decreases expression EXP lead chloride results in decreased expression of VIM protein CTD PMID:24419708 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
G WNT4 Wnt family member 4 multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in decreased expression of WNT4 mRNA CTD PMID:18654764 NCBI chr 1:22,117,313...22,143,097
Ensembl chr 1:22,117,313...22,143,969 		JBrowse link
G YY1 YY1 transcription factor multiple interactions EXP [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] affects the expression of YY1 mRNA CTD PMID:18654764 NCBI chr14:100,239,144...100,282,788
Ensembl chr14:100,238,298...100,282,788 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26040
    chemical entity 26019
      molecular entity 25997
        inorganic molecular entity 25320
          inorganic salt 16307
            inorganic chloride 8161
              lead(II) chloride 130
Path 2
Term Annotations click to browse term
  CHEBI ontology 26040
    subatomic particle 26015
      composite particle 26015
        hadron 26015
          baryon 26015
            nucleon 26015
              atomic nucleus 26015
                atom 26015
                  main group element atom 25840
                    p-block element atom 25840
                      halogen 21140
                        chlorine atom 20247
                          chlorine molecular entity 20247
                            elemental chlorine 8463
                              monoatomic chlorine 8446
                                chloride 8446
                                  chloride salt 8446
                                    inorganic chloride 8161
                                      lead(II) chloride 130
paths to the root