HNRNPD (heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa))

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Keyword

Gene: HNRNPD (heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)) Homo sapiens

Symbol:

HNRNPD

Name:

heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)

Description:

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

ARE-binding protein AUFI, type A; AU-rich element RNA-binding protein 1; AUF1; AUF1A; heterogeneous nuclear ribonucleoprotein D0; hnRNP D0; hnRNPD0; HNRPD; OTTHUMP00000160798; OTTHUMP00000160799; OTTHUMP00000160800; OTTHUMP00000219401; OTTHUMP00000219403; OTTHUMP00000219469; P37; rna binding protein p45auf1

Orthologs:

Mus musculus : Hnrnpd (heterogeneous nuclear ribonucleoprotein D) MGI
Rattus norvegicus : Hnrpd (heterogeneous nuclear ribonucleoprotein D)

Related Pseudogenes:

HNRNPDP

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	4	83,090,112 - 83,110,809	-	NCBI
Human Genome Assembly HuRef	4	79,014,546 - 79,035,236	-	NCBI
Human Genome Assembly GRCh37	4	83,274,467 - 83,295,149	-	NCBI
Human Genome Assembly Build 36	4	83,493,491 - 83,514,173	-	NCBI
Human Cytogenetic Map	4	q21		NCBI
Human Genome Assembly	4	83,631,645 - 83,652,328		NCBI