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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:mismatch repair pathway
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Accession:PW:0000662 term browser browse the term
Definition:The mismatch repair pathway assures the maintenance of normal Watson-Crick base pairing. Bases incorrectly matched during DNA replication are removed and replaced with the correct ones.
Synonyms:related_synonym: MMR pathway;   Mismatch Repair
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mismatch repair pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exo1 exonuclease 1 ISO
IEA 		KEGG
RGD		 PMID:18157157 rno:03430, RGD:2306716 NCBI chr13:90,341,947...90,366,861
Ensembl chr13:90,342,018...90,366,861 		JBrowse link
G Hmgb1 high mobility group box 1 ISO RGD PMID:18157157 RGD:2306716 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327 		JBrowse link
G Lig1 DNA ligase 1 ISO
IEA 		KEGG
RGD		 PMID:18157157 rno:03430, RGD:2306716 NCBI chr 1:83,243,043...83,281,707
Ensembl chr 1:83,219,545...83,281,708 		JBrowse link
G Mlh1 mutL homolog 1 ISO
IEA 		KEGG
RGD		 PMID:18157157 rno:03430, RGD:2306716 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011 		JBrowse link
G Mlh3 mutL homolog 3 ISO
IEA 		KEGG
RGD		 PMID:18157157 rno:03430, RGD:2306716 NCBI chr 6:110,612,535...110,649,408
Ensembl chr 6:110,612,535...110,648,999 		JBrowse link
G Msh2 mutS homolog 2 ISO
IEA 		KEGG
RGD		 PMID:18157157 rno:03430, RGD:2306716 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503 		JBrowse link
G Msh3 mutS homolog 3 ISO
IEA 		KEGG
RGD		 PMID:18157157 rno:03430, RGD:2306716 NCBI chr 2:25,179,400...25,320,857
Ensembl chr 2:25,179,400...25,321,102 		JBrowse link
G Msh6 mutS homolog 6 ISO RGD PMID:18157157 RGD:2306716 NCBI chr 6:12,316,190...12,333,505
Ensembl chr 6:12,316,198...12,333,844 		JBrowse link
G Pcna proliferating cell nuclear antigen ISO
IEA 		KEGG
RGD		 PMID:18157157 rno:03430, RGD:2306716 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Pms1 PMS1 homolog 1, mismatch repair system component ISO RGD PMID:18157157 RGD:2306716 NCBI chr 9:55,721,393...55,832,225
Ensembl chr 9:55,745,374...55,832,221 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component ISO
IEA 		KEGG
RGD		 PMID:18157157 rno:03430, RGD:2306716 NCBI chr12:15,790,478...15,814,790
Ensembl chr12:15,790,478...15,815,248 		JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit ISO
IEA 		KEGG
RGD		 PMID:18157157 rno:03430, RGD:2306716 NCBI chr 1:104,161,984...104,178,074
Ensembl chr 1:104,162,016...104,172,982 		JBrowse link
G Pold2 DNA polymerase delta 2, accessory subunit ISO
IEA 		KEGG
RGD		 PMID:18157157 rno:03430, RGD:2306716 NCBI chr14:84,962,933...84,969,148
Ensembl chr14:84,962,022...84,967,874 		JBrowse link
G Pold3 DNA polymerase delta 3, accessory subunit ISO
IEA 		KEGG
RGD		 PMID:18157157 rno:03430, RGD:2306716 NCBI chr 1:163,830,217...163,870,015
Ensembl chr 1:163,830,437...163,869,202 		JBrowse link
G Pold4 DNA polymerase delta 4, accessory subunit ISO
IEA 		KEGG
RGD		 PMID:18157157 rno:03430, RGD:2306716 NCBI chr 1:210,956,110...210,957,863
Ensembl chr 1:210,956,099...210,957,860 		JBrowse link
G Rfc1 replication factor C subunit 1 ISO
IEA 		KEGG
RGD		 PMID:18157157 rno:03430, RGD:2306716 NCBI chr14:43,319,768...43,395,028
Ensembl chr14:43,319,935...43,395,026 		JBrowse link
G Rfc2 replication factor C subunit 2 ISO
IEA 		KEGG
RGD		 PMID:18157157 rno:03430, RGD:2306716 NCBI chr12:27,756,920...27,770,049
Ensembl chr12:27,756,922...27,770,025 		JBrowse link
G Rfc3 replication factor C subunit 3 ISO
IEA 		KEGG
RGD		 PMID:18157157 rno:03430, RGD:2306716 NCBI chr12:5,836,546...5,847,331
Ensembl chr12:5,836,553...5,847,340 		JBrowse link
G Rfc4 replication factor C subunit 4 ISO
IEA 		KEGG
RGD		 PMID:18157157 rno:03430, RGD:2306716 NCBI chr11:91,254,273...91,268,727
Ensembl chr11:91,254,243...91,268,730 		JBrowse link
G Rfc5 replication factor C subunit 5 ISO
IEA 		KEGG
RGD		 PMID:18157157 rno:03430, RGD:2306716 NCBI chr12:44,868,322...44,877,879
Ensembl chr12:44,862,329...44,878,151 		JBrowse link
G Rpa1 replication protein A1 ISO
IEA 		KEGG
RGD		 PMID:18157157 rno:03430, RGD:2306716 NCBI chr10:60,647,185...60,698,279
Ensembl chr10:60,647,185...60,698,279 		JBrowse link
G Rpa2 replication protein A2 ISO
IEA 		KEGG
RGD		 PMID:18157157 rno:03430, RGD:2306716 NCBI chr 5:150,260,668...150,271,329
Ensembl chr 5:150,260,723...150,271,546 		JBrowse link
G Rpa3 replication protein A3 ISO
IEA 		KEGG
RGD		 PMID:18157157 rno:03430, RGD:2306716 NCBI chr 4:37,270,966...37,273,997
Ensembl chr 4:37,270,966...37,274,183 		JBrowse link
G Ssbp1 single stranded DNA binding protein 1 IEA KEGG rno:03430 NCBI chr 4:70,232,740...70,242,824
Ensembl chr 4:70,232,794...70,243,700 		JBrowse link
altered mismatch repair pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 ISO RGD PMID:11900875 PMID:19078924 RGD:2306714, RGD:4143515 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011 		JBrowse link
G Msh2 mutS homolog 2 ISO RGD PMID:11900875 RGD:2306714 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503 		JBrowse link
G Msh6 mutS homolog 6 ISO RGD PMID:11900875 RGD:2306714 NCBI chr 6:12,316,190...12,333,505
Ensembl chr 6:12,316,198...12,333,844 		JBrowse link
G Pms1 PMS1 homolog 1, mismatch repair system component ISO RGD PMID:11900875 RGD:2306714 NCBI chr 9:55,721,393...55,832,225
Ensembl chr 9:55,745,374...55,832,221 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component ISO RGD PMID:11900875 RGD:2306714 NCBI chr12:15,790,478...15,814,790
Ensembl chr12:15,790,478...15,815,248 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    regulatory pathway 3864
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1738
        DNA repair pathway 384
          single-strand DNA repair pathway 83
            mismatch repair pathway 24
              altered mismatch repair pathway 5
Path 2
Term Annotations click to browse term
  pathway 6091
    regulatory pathway 3864
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1738
        DNA damage response pathway 405
          DNA repair pathway 384
            single-strand DNA repair pathway 83
              mismatch repair pathway 24
                altered mismatch repair pathway 5
paths to the root