Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Trafd1 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Trafd1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TRAFD1 mRNA | CTD | PMID:36331819 | Trafd1 | Rat | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of TRAFD1 mRNA | CTD | PMID:25380136 | Trafd1 | Rat | 17beta-estradiol | decreases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of TRAFD1 mRNA | CTD | PMID:31614463 | Trafd1 | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Trafd1 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | Trafd1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Trafd1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TRAFD1 mRNA | CTD | PMID:21570461 | Trafd1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TRAFD1 mRNA | CTD | PMID:33387578 | Trafd1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of TRAFD1 mRNA | CTD | PMID:34747641 | Trafd1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TRAFD1 mRNA | CTD | PMID:22903824 | Trafd1 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of TRAFD1 mRNA | CTD | PMID:30851411 | Trafd1 | Rat | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of TRAFD1 mRNA | CTD | PMID:25380136 | Trafd1 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of TRAFD1 mRNA | CTD | PMID:36041667 | Trafd1 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of TRAFD1 mRNA | CTD | PMID:24780913 | Trafd1 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of TRAFD1 mRNA | CTD | PMID:31881176 | Trafd1 | Rat | adefovir pivoxil | decreases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | adefovir dipivoxil results in decreased expression of TRAFD1 mRNA | CTD | PMID:25596134 | Trafd1 | Rat | aflatoxin B1 | decreases methylation | ISO | TRAFD1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of TRAFD1 3' UTR | CTD | PMID:30157460 | Trafd1 | Rat | all-trans-retinoic acid | increases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of TRAFD1 mRNA | CTD | PMID:33167477 | Trafd1 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of TRAFD1 mRNA | CTD | PMID:16483693 | Trafd1 | Rat | antirheumatic drug | decreases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of TRAFD1 mRNA | CTD | PMID:24449571 | Trafd1 | Rat | aristolochic acid A | increases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of TRAFD1 mRNA | CTD | PMID:33212167 | Trafd1 | Rat | azoxystrobin | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TRAFD1 mRNA | CTD | PMID:33854195 | Trafd1 | Rat | benzo[a]pyrene | increases expression | ISO | Trafd1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of TRAFD1 mRNA | CTD | PMID:22228805 | Trafd1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TRAFD1 mRNA | CTD | PMID:25181051 | Trafd1 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of TRAFD1 mRNA | CTD | PMID:36041667 | Trafd1 | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of TRAFD1 mRNA | CTD | PMID:36041667 | Trafd1 | Rat | bortezomib | increases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Bortezomib results in increased expression of TRAFD1 mRNA | CTD | PMID:20977926 | Trafd1 | Rat | C60 fullerene | increases expression | EXP | | 6480464 | fullerene C60 results in increased expression of TRAFD1 mRNA | CTD | PMID:19167457 | Trafd1 | Rat | cadmium dichloride | decreases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of TRAFD1 mRNA | CTD | PMID:25596134 and PMID:38568856 | Trafd1 | Rat | caffeine | affects phosphorylation | ISO | TRAFD1 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of TRAFD1 protein | CTD | PMID:35688186 | Trafd1 | Rat | capsaicin | increases expression | EXP | | 6480464 | Capsaicin results in increased expression of TRAFD1 mRNA | CTD | PMID:16278290 | Trafd1 | Rat | carbon nanotube | increases expression | ISO | Trafd1 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of TRAFD1 mRNA | CTD | PMID:25554681 | Trafd1 | Rat | chlordecone | decreases expression | ISO | Trafd1 (Mus musculus) | 6480464 | Chlordecone results in decreased expression of TRAFD1 mRNA | CTD | PMID:29980752 | Trafd1 | Rat | chlorpromazine | decreases expression | EXP | | 6480464 | Chlorpromazine results in decreased expression of TRAFD1 mRNA | CTD | PMID:25596134 | Trafd1 | Rat | chlorpyrifos | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TRAFD1 mRNA | CTD | PMID:33854195 | Trafd1 | Rat | chromium(6+) | affects expression | ISO | Trafd1 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of TRAFD1 mRNA | CTD | PMID:28472532 | Trafd1 | Rat | cidofovir anhydrous | increases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Cidofovir results in increased expression of TRAFD1 mRNA | CTD | PMID:25596134 | Trafd1 | Rat | cisplatin | increases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of TRAFD1 mRNA | CTD | PMID:25596134 | Trafd1 | Rat | clodronic acid | affects expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Clodronic Acid affects the expression of TRAFD1 mRNA | CTD | PMID:25596134 | Trafd1 | Rat | clofibrate | decreases expression | ISO | Trafd1 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of TRAFD1 mRNA | CTD | PMID:23811191 | Trafd1 | Rat | copper(II) chloride | decreases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | cupric chloride results in decreased expression of TRAFD1 mRNA | CTD | PMID:38568856 | Trafd1 | Rat | coumarin | decreases phosphorylation | ISO | TRAFD1 (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of TRAFD1 protein | CTD | PMID:35688186 | Trafd1 | Rat | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of TRAFD1 mRNA | CTD | PMID:25596134 | Trafd1 | Rat | DDE | decreases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in decreased expression of TRAFD1 mRNA | CTD | PMID:38568856 | Trafd1 | Rat | diethylstilbestrol | decreases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Diethylstilbestrol results in decreased expression of TRAFD1 mRNA | CTD | PMID:36621641 | Trafd1 | Rat | dioxygen | decreases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Oxygen deficiency results in decreased expression of TRAFD1 mRNA | CTD | PMID:25596134 | Trafd1 | Rat | doxorubicin | decreases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of TRAFD1 mRNA | CTD | PMID:29803840 | Trafd1 | Rat | elemental selenium | increases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Selenium results in increased expression of TRAFD1 mRNA | CTD | PMID:19244175 | Trafd1 | Rat | enzyme inhibitor | multiple interactions | ISO | TRAFD1 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of TRAFD1 protein | CTD | PMID:23301498 | Trafd1 | Rat | ethyl methanesulfonate | increases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of TRAFD1 mRNA | CTD | PMID:23649840 | Trafd1 | Rat | fenofibrate | decreases expression | EXP | | 6480464 | Fenofibrate results in decreased expression of TRAFD1 mRNA | CTD | PMID:25596134 | Trafd1 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of TRAFD1 mRNA | CTD | PMID:24136188 | Trafd1 | Rat | formaldehyde | increases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of TRAFD1 mRNA | CTD | PMID:23649840 | Trafd1 | Rat | FR900359 | affects phosphorylation | ISO | TRAFD1 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of TRAFD1 protein | CTD | PMID:37730182 | Trafd1 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of TRAFD1 mRNA | CTD | PMID:33387578 | Trafd1 | Rat | glyphosate | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TRAFD1 mRNA | CTD | PMID:33854195 | Trafd1 | Rat | ifosfamide | increases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Ifosfamide results in increased expression of TRAFD1 mRNA | CTD | PMID:25596134 | Trafd1 | Rat | imidacloprid | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TRAFD1 mRNA | CTD | PMID:33854195 | Trafd1 | Rat | ivermectin | decreases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of TRAFD1 protein | CTD | PMID:32959892 | Trafd1 | Rat | metformin | decreases expression | EXP | | 6480464 | Metformin results in decreased expression of TRAFD1 mRNA | CTD | PMID:25596134 | Trafd1 | Rat | methyl methanesulfonate | increases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of TRAFD1 mRNA | CTD | PMID:23649840 | Trafd1 | Rat | nickel atom | increases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Nickel results in increased expression of TRAFD1 mRNA | CTD | PMID:25583101 | Trafd1 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of TRAFD1 mRNA | CTD | PMID:25729387 | Trafd1 | Rat | paracetamol | affects expression | ISO | Trafd1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of TRAFD1 mRNA | CTD | PMID:17562736 | Trafd1 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of TRAFD1 mRNA | CTD | PMID:33387578 | Trafd1 | Rat | paracetamol | decreases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of TRAFD1 mRNA | CTD | PMID:21420995 | Trafd1 | Rat | pentachlorophenol | increases expression | ISO | Trafd1 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of TRAFD1 mRNA | CTD | PMID:23892564 | Trafd1 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Trafd1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TRAFD1 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of TRAFD1 mRNA | CTD | PMID:36331819 | Trafd1 | Rat | propiconazole | decreases expression | ISO | Trafd1 (Mus musculus) | 6480464 | propiconazole results in decreased expression of TRAFD1 mRNA | CTD | PMID:21278054 | Trafd1 | Rat | rac-lactic acid | decreases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of TRAFD1 mRNA | CTD | PMID:30851411 | Trafd1 | Rat | selenium atom | increases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Selenium results in increased expression of TRAFD1 mRNA | CTD | PMID:19244175 | Trafd1 | Rat | silver atom | decreases expression | ISO | Trafd1 (Mus musculus) | 6480464 | Silver results in decreased expression of TRAFD1 mRNA | CTD | PMID:27131904 | Trafd1 | Rat | silver(0) | decreases expression | ISO | Trafd1 (Mus musculus) | 6480464 | Silver results in decreased expression of TRAFD1 mRNA | CTD | PMID:27131904 | Trafd1 | Rat | sulforaphane | decreases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | sulforaphane results in decreased expression of TRAFD1 mRNA | CTD | PMID:31838189 | Trafd1 | Rat | sunitinib | decreases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of TRAFD1 mRNA | CTD | PMID:31533062 | Trafd1 | Rat | temozolomide | increases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of TRAFD1 mRNA | CTD | PMID:31758290 | Trafd1 | Rat | thiabendazole | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TRAFD1 mRNA | CTD | PMID:33854195 | Trafd1 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of TRAFD1 mRNA | CTD | PMID:34492290 | Trafd1 | Rat | thiram | decreases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Thiram results in decreased expression of TRAFD1 mRNA | CTD | PMID:38568856 | Trafd1 | Rat | titanium dioxide | decreases methylation | ISO | Trafd1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of TRAFD1 gene | CTD | PMID:35295148 | Trafd1 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of TRAFD1 mRNA | CTD | PMID:25729387 | Trafd1 | Rat | triphenyl phosphate | affects expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of TRAFD1 mRNA | CTD | PMID:37042841 | Trafd1 | Rat | trovafloxacin | increases expression | ISO | Trafd1 (Mus musculus) | 6480464 | trovafloxacin results in increased expression of TRAFD1 mRNA | CTD | PMID:35537566 | Trafd1 | Rat | urethane | increases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Urethane results in increased expression of TRAFD1 mRNA | CTD | PMID:28818685 | Trafd1 | Rat | valproic acid | increases expression | ISO | Trafd1 (Mus musculus) | 6480464 | Valproic Acid results in increased expression of TRAFD1 mRNA | CTD | PMID:20546886 and PMID:21427059 | Trafd1 | Rat | vitamin E | increases expression | ISO | TRAFD1 (Homo sapiens) | 6480464 | Vitamin E results in increased expression of TRAFD1 mRNA | CTD | PMID:19244175 | |