Ppih (peptidylprolyl isomerase H)

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Gene: Ppih (peptidylprolyl isomerase H) Rattus norvegicus

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Symbol:

Ppih

Name:

peptidylprolyl isomerase H

RGD ID:

1564921

Description:

Predicted to enable cyclosporin A binding activity; peptidyl-prolyl cis-trans isomerase activity; and ribonucleoprotein complex binding activity. Predicted to be involved in positive regulation of viral genome replication and protein folding. Predicted to be located in nuclear speck. Predicted to be part of U4/U6 snRNP and U4/U6 x U5 tri-snRNP complex. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Orthologous to human PPIH (peptidylprolyl isomerase H); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; alpha-Zearalanol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC366461; peptidyl-prolyl cis-trans isomerase H; peptidylprolyl isomerase H (cyclophilin H); RGD1564921; similar to peptidyl prolyl isomerase H

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PPIH (peptidylprolyl isomerase H)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Ppih (peptidyl prolyl isomerase H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ppih (peptidylprolyl isomerase H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PPIH (peptidylprolyl isomerase H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PPIH (peptidylprolyl isomerase H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ppih (peptidylprolyl isomerase H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PPIH (peptidylprolyl isomerase H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PPIH (peptidylprolyl isomerase H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ppih (peptidylprolyl isomerase H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	AKAP12 (A-kinase anchoring protein 12)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	PPIH (peptidylprolyl isomerase H)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ppih (peptidyl prolyl isomerase H)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ppihl (peptidyl prolyl isomerase H like)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ppih (peptidylprolyl isomerase H (cyclophilin H))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG17266	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	cyn-11	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ppih	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	138,191,624 - 138,209,625 (-)	NCBI		GRCr8
mRatBN7.2	5	132,906,324 - 132,924,341 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	132,906,328 - 132,924,267 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	135,633,875 - 135,652,694 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	137,390,334 - 137,409,153 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	137,410,930 - 137,429,749 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	138,343,934 - 138,361,743 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	138,352,916 - 138,361,702 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	142,160,007 - 142,178,024 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	139,959,365 - 139,969,320 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	5	131,431,800 - 131,449,612 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease dominant intermediate C (ISO)

glucose transporter type 1 deficiency syndrome 1 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17alpha-ethynylestradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,3-dimethoxynaphthalene-1,4-dione (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-methylcholanthrene (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (EXP)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

alpha-Zearalanol (EXP)

antimony(0) (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

cadmium dichloride (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

chromium atom (ISO)

clofibrate (ISO)

cobalt dichloride (ISO)

cyclosporin A (ISO)

decabromodiphenyl ether (ISO)

dextran sulfate (ISO)

diarsenic trioxide (ISO)

dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate (ISO)

doxorubicin (ISO)

ivermectin (ISO)

mercury atom (ISO)

mercury(0) (ISO)

methamphetamine (ISO)

methotrexate (ISO)

methyl methanesulfonate (ISO)

ozone (ISO)

paracetamol (ISO)

perfluorooctanoic acid (EXP)

phenethyl isothiocyanate (EXP)

phenobarbital (ISO)

pirinixic acid (ISO)

potassium dichromate (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

tamoxifen (ISO)

testosterone (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

Tributyltin oxide (ISO)

trimellitic anhydride (ISO)

triptonide (ISO)

troglitazone (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Yessotoxin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

positive regulation of viral genome replication (ISO)

protein folding (IBA)

regulation of transcription by RNA polymerase II (IEA)

Cellular Component

cytoplasm (IBA,ISO)

intracellular membrane-bounded organelle (IBA)

nuclear speck (ISO)

U4/U6 snRNP (ISO)

U4/U6 x U5 tri-snRNP complex (ISO)

Molecular Function

cyclosporin A binding (IBA)

peptidyl-prolyl cis-trans isomerase activity (IBA,ISO)

protein binding (ISO)

ribonucleoprotein complex binding (ISO)

RNA polymerase II CTD heptapeptide repeat P3 isomerase activity (IEA)

RNA polymerase II CTD heptapeptide repeat P6 isomerase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

spliceosome pathway (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Spliceosomal immunophilins.	Mesa A, etal., FEBS Lett. 2008 Jul 9;582(16):2345-51. doi: 10.1016/j.febslet.2008.06.006. Epub 2008 Jun 9.
3.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:9570313	PMID:19932913	PMID:20676357

Genomics

Comparative Map Data

Ppih
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	138,191,624 - 138,209,625 (-)	NCBI		GRCr8
mRatBN7.2	5	132,906,324 - 132,924,341 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	132,906,328 - 132,924,267 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	135,633,875 - 135,652,694 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	137,390,334 - 137,409,153 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	137,410,930 - 137,429,749 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	138,343,934 - 138,361,743 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	138,352,916 - 138,361,702 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	142,160,007 - 142,178,024 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	139,959,365 - 139,969,320 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	5	131,431,800 - 131,449,612 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

PPIH
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	42,658,423 - 42,681,654 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	42,658,335 - 42,676,758 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	43,124,094 - 43,142,429 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	42,896,635 - 42,915,016 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	42,793,140 - 42,811,521	NCBI
Celera	1	41,405,975 - 41,424,356 (+)	NCBI		Celera
Cytogenetic Map	1	p34.2	NCBI
HuRef	1	41,244,218 - 41,262,600 (+)	NCBI		HuRef
CHM1_1	1	43,240,906 - 43,259,287 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	42,528,918 - 42,552,149 (+)	NCBI		T2T-CHM13v2.0

Ppih
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	119,157,207 - 119,177,720 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	119,157,207 - 119,177,743 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	119,300,010 - 119,320,523 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	119,300,010 - 119,320,546 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	118,972,615 - 118,993,128 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	118,797,947 - 118,818,411 (-)	NCBI		MGSCv36	mm8
Celera	4	118,027,842 - 118,048,366 (-)	NCBI		Celera
Cytogenetic Map	4	D2.1	NCBI
cM Map	4	55.34	NCBI

Ppih
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955537	2,211,410 - 2,230,452 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955537	2,211,566 - 2,229,444 (+)	NCBI	ChiLan1.0	ChiLan1.0

PPIH
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	184,130,421 - 184,153,502 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	183,272,085 - 183,295,157 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	41,958,260 - 41,981,598 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	43,336,039 - 43,354,609 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	43,336,039 - 43,353,898 (+)	Ensembl	panpan1.1		panPan2

PPIH
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	671,323 - 689,627 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	15	671,324 - 689,544 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	926,045 - 944,371 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	752,681 - 771,039 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	15	752,682 - 770,962 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	15	662,128 - 680,381 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	723,569 - 741,836 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	738,714 - 757,011 (-)	NCBI		UU_Cfam_GSD_1.0

Ppih
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	58,179,131 - 58,200,103 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	24,003,827 - 24,024,922 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	24,003,963 - 24,024,885 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PPIH
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	168,742,005 - 168,760,286 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	168,741,999 - 168,760,350 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	156,223,015 - 156,241,360 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PPIH
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	90,250,959 - 90,275,275 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	90,256,081 - 90,274,751 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	26,635,055 - 26,659,466 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ppih
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624892	1,916,912 - 1,935,875 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624892	1,916,873 - 1,935,458 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ppih
68 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	132
Count of miRNA genes:	102
Interacting mature miRNAs:	109
Transcripts:	ENSRNOT00000064712, ENSRNOT00000067943
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331796	Thshl2	Thyroid stimulating hormone level QTL 2	2.3		blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	5	97059760	147465714	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	124965598	166875058	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40128307	148607290	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	111416838	156416838	Rat
1300122	Wbc1	White blood cell count QTL 1	2.75		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	5	125392826	139989768	Rat
7365049	Bp359	Blood pressure QTL 359			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	128071929	134724733	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	94858972	143070159	Rat
70156	Niddm30	Non-insulin dependent diabetes mellitus QTL 30	3.98		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	5	129132447	151006154	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	128506074	166875058	Rat
1331803	Rf32	Renal function QTL 32	2.798		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	129132428	143070159	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	60293434	161481680	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	131345754	166875058	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	106906205	151906205	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	106906205	151906205	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	82394392	166664054	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	127798274	166875058	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	132717196	165560427	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	106906205	151906205	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	121846814	166846814	Rat
1581505	Rf54	Renal function QTL 54			kidney physiology trait (VT:0002136)	kidney 20-HETE level (CMO:0001854)	5	128033842	133011550	Rat
2317753	Glom24	Glomerulus QTL 24	3.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	5	97570330	136479578	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	128506074	166875058	Rat
8657050	Bw146	Body weight QTL 146	19.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	108938288	153938288	Rat
1581510	Cm54	Cardiac mass QTL 54	3.4	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	120740824	143608494	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	50328551	141643988	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	35189153	141643988	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
2317056	Wbc3	White blood cell count QTL 3	2.51	0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	5	105999803	150999803	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	128924607	166875058	Rat
7394710	Emca12	Estrogen-induced mammary cancer QTL 12			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	124160767	133749643	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	126424772	166875058	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	108845856	153845856	Rat
2293642	Bss37	Bone structure and strength QTL 37	4.64	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	120740824	151018848	Rat
1578673	Bmd13	Bone mineral density QTL 13	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	5	103689353	148689353	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	130130159	166875058	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	106906205	151906205	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	111416838	156416838	Rat
631527	Tls1	T-lymphoma susceptibility QTL 1	0	0.001	thymus integrity trait (VT:0010555)	post-insult time to onset of T-cell lymphoma (CMO:0001907)	5	90450144	135450144	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	106906205	151906205	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	111416838	156416838	Rat
61426	Scl2	Serum cholesterol level QTL 2	7.3	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	59793399	143070159	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	69540295	151018848	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	111416838	156416838	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	108845856	153845856	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	127798274	166875058	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	99216724	148607142	Rat

Markers in Region

D5Got61

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	132,914,427 - 132,914,706 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	138,351,877 - 138,352,155	NCBI	Rnor6.0
Rnor_5.0	5	142,168,168 - 142,168,446	UniSTS	Rnor5.0
RGSC_v3.4	5	139,891,233 - 139,891,512	RGD	RGSC3.4
RGSC_v3.4	5	139,891,234 - 139,891,512	UniSTS	RGSC3.4
RGSC_v3.1	5	139,896,460 - 139,896,738	RGD
Celera	5	131,439,743 - 131,440,021	UniSTS
RH 3.4 Map	5	870.8	UniSTS
RH 3.4 Map	5	870.8	RGD
RH 2.0 Map	5	863.1	RGD
Cytogenetic Map	5	q36	UniSTS

RH138343

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	132,912,194 - 132,912,346 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	138,349,644 - 138,349,795	NCBI	Rnor6.0
Rnor_5.0	5	142,165,717 - 142,165,868	UniSTS	Rnor5.0
RGSC_v3.4	5	139,889,001 - 139,889,152	UniSTS	RGSC3.4
Celera	5	131,437,510 - 131,437,661	UniSTS
RH 3.4 Map	5	866.2	UniSTS
RH 3.4 Map	5	868.5	UniSTS
Cytogenetic Map	5	q36	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001399453	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001073803	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006225499	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006225500	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006238771	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006238772	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC098918	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000064712 ⟹ ENSRNOP00000063468

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	132,916,003 - 132,924,267 (-)	Ensembl
Rnor_6.0 Ensembl	5	138,353,452 - 138,361,702 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000067943 ⟹ ENSRNOP00000059353

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	132,915,467 - 132,924,267 (-)	Ensembl
Rnor_6.0 Ensembl	5	138,352,916 - 138,361,702 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000098415 ⟹ ENSRNOP00000076976

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	132,915,757 - 132,924,267 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000108155 ⟹ ENSRNOP00000088556

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	132,906,328 - 132,924,265 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112897 ⟹ ENSRNOP00000079411

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	132,912,180 - 132,924,265 (-)	Ensembl

RefSeq Acc Id:

NM_001399453 ⟹ NP_001386382

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	138,191,624 - 138,209,580 (-)	NCBI
mRatBN7.2	5	132,906,324 - 132,924,280 (-)	NCBI

RefSeq Acc Id:

XM_006238771 ⟹ XP_006238833

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	138,197,493 - 138,209,625 (-)	NCBI
mRatBN7.2	5	132,912,046 - 132,924,341 (-)	NCBI
Rnor_6.0	5	138,349,495 - 138,361,743 (-)	NCBI
Rnor_5.0	5	142,160,007 - 142,178,024 (-)	NCBI

Sequence:

show sequence

CCTGTCACCGGAAGTTAGGCTTCTACTTCCGAGTCAAAGCCATGGCGGTGGCAAATTCAAGTCC
CGTCAATCCAGTGGTCTTCTTTGATGTCAGTATTGGCGGCCAGGAAGTTGGTCGCATGAAGATC
GAGCTCTTTGCAGACGTGGTGCCTAAGACGGCAGAGAACTTTAGGCAGTTCTGCACTGGAGAAT
TCAGAAAAGACGGCGTTCCGATAGGATACAAAGGAAGCACCTTCCACAGGGTCATAAAGGATTT
CATGATTCAGGGTGGTTTTGTTAATGGCGATGGTACTGGAGTCGCCAGTATTTACCGGGGTCCA
TTTGCAGATGAAAATTTTAAACTTAGACACTCGGCTCCAGGCCTGCTTTCCATGGCAAACAGTG
GTCCCAGTACAAATGGCTGCCAGTTCTTTATCACGTGTTCTAAGTGTGATTGGCTGGATGGAAA
GCATGTAGTGTTTGGGAAAATCATTGATGGACTTCTAGTGATGAGGAAGATTGAGAATGTTCCC
ACAGGCCCCAACAATAAGCCCAAACTGCCAGTGGTGATCTCACAGTGTGGGGAAATGTAATCTA
GACAAGACTGAACCAGACACAAAAAGAAATGCACCAAAAAACCTCTGGTGGTGTTTTGGCGGCT
TCTTGCCGCTTCCTCGGACTTGGACGGATTGGCAGAGTGATGTCAGCTGATACTGACTCGTGAG
GTGTTTTGTTGAAGCAAGACTTGTGGGATCTTTACTTCATTGAGAGAAGCACAGCAGAGAACTG
CACTTGGTATCCATGTGGGCACTGGTCCCTCCTGCTGACACTTGCTGATTCATCGGAGGTCTGG
CTGTTCCTGCTGGGTGACACCATTGCTGCTGATTCATGTCTGCCATCTTGTCTGCTGTACTGGA
CTGCTGGTATCCTGACAATTGGAGATTGAAATTACCCCAAGGAACTACTTCTAAACTACAGACA
GCAGAGCCTCTCGGTTTCCTCTGGATAGACCTGCCGATGCTGATTCGTGTGAACTGCACTGATT
ATATCCTGACAGCACAGTTGGATTTTCTCCAAAGAACTATTTCTAACAAGTTCACTTCCCTGTA
ACCTAATAACCTCTTTCCCTCTACCTTTGGTGGGTGGTGGACTAGAAGGGAGGTTAAAGCGTTT
AAGAACCCTTATTAAAGACCTGCACCGGGGCCAGGGTCTCACTATATCACCTTGACTAGCCTGT
CTCCAACTCATGGAGATGCCCTGTCTTCCTTGTGCCTTGCGGAAGGCATGCAGCAACATGGCTG
CCAGTCTCTTTTTCACATAGAGATCTAGTCAAATACCAAACAACTCCA

hide sequence

RefSeq Acc Id:

XM_006238772 ⟹ XP_006238834

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	138,197,493 - 138,209,625 (-)	NCBI
mRatBN7.2	5	132,912,046 - 132,924,341 (-)	NCBI
Rnor_6.0	5	138,349,495 - 138,361,743 (-)	NCBI
Rnor_5.0	5	142,160,007 - 142,178,024 (-)	NCBI

Sequence:

show sequence

CCTGTCACCGGAAGTTAGGCTTCTACTTCCGAGTCAAAGCCATGGCGGTGGCAAATTCAAGTCC
CGTCAATCCAGTGGTCTTCTTTGATGTCAGTATTGGCGGCCAGGAAGTTGGTCGCATGAAGATC
GAGCTCTTTGCAGACGTGGTGCCTAAGACGGCAGAGAACTTTAGGCAGTTCTGCACTGGAGAAT
TCAGAAAAGACGGCGTTCCGATAGGATACAAAGGAAGCACCTTCCACAGGGTCATAAAGGATTT
CATGATTCAGGGTGGTTTTGTTAATGGCGATGGTACTGGAGTCGCCAGTATTTACCGGGGTCCA
TTTGCAGATGAAAATTTTAAACTTAGACACTCGGCTCCAGGCCTGCTTTCCATGGCAAACAGTG
GTCCCAGTACAAATGGCTGCCAGTTCTTTATCACGTGTTCTAAGTGTGATTGGCTGGATGGAAA
GCATGTAGTGTTTGGGAAAATCATTGATGGACTTCTAGTGATGAGGAAGATTGAGAATGTTCCC
ACAGGCCCCAACAATAAGCCCAAACTGCCAGTGGTGATCTCACAGTGTGGGGAAATGTAATCTA
GACAAGACTGAACCAGGTGAAAGGATGTTTTCTGAAACAGACACAAAAAGAAATGCACCAAAAA
ACCTCTGGTGGTGTTTTGGCGGCTTCTTGCCGCTTCCTCGGACTTGGACGGATTGGCAGAGTGA
TGTCAGCTGATACTGACTCGTGAGGTGTTTTGTTGAAGCAAGACTTGTGGGATCTTTACTTCAT
TGAGAGAAGCACAGCAGAGAACTGCACTTGGTATCCATGTGGGCACTGGTCCCTCCTGCTGACA
CTTGCTGATTCATCGGAGGTCTGGCTGTTCCTGCTGGGTGACACCATTGCTGCTGATTCATGTC
TGCCATCTTGTCTGCTGTACTGGACTGCTGGTATCCTGACAATTGGAGATTGAAATTACCCCAA
GGAACTACTTCTAAACTACAGACAGCAGAGCCTCTCGGTTTCCTCTGGATAGACCTGCCGATGC
TGATTCGTGTGAACTGCACTGATTATATCCTGACAGCACAGTTGGATTTTCTCCAAAGAACTAT
TTCTAACAAGTTCACTTCCCTGTAACCTAATAACCTCTTTCCCTCTACCTTTGGTGGGTGGTGG
ACTAGAAGGGAGGTTAAAGCGTTTAAGAACCCTTATTAAAGACCTGCACCGGGGCCAGGGTCTC
ACTATATCACCTTGACTAGCCTGTCTCCAACTCATGGAGATGCCCTGTCTTCCTTGTGCCTTGC
GGAAGGCATGCAGCAACATGGCTGCCAGTCTCTTTTTCACATAGAGATCTAGTCAAATACCAAA
CAACTCCA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001386382	(Get FASTA)	NCBI Sequence Viewer
	XP_006238833	(Get FASTA)	NCBI Sequence Viewer
	XP_006238834	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL90120	(Get FASTA)	NCBI Sequence Viewer
	EDL90121	(Get FASTA)	NCBI Sequence Viewer
	EDL90122	(Get FASTA)	NCBI Sequence Viewer
	EDL90123	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000059353.3
	ENSRNOP00000063468.3
	ENSRNOP00000076976.1
	ENSRNOP00000079411.1
	ENSRNOP00000088556.1

RefSeq Acc Id:	XP_006238833 ⟸ XM_006238771
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZMT9 (UniProtKB/TrEMBL), A6JZN2 (UniProtKB/TrEMBL), A0A8I6A6F0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGST FHRVIKDFMIQGGFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCS KCDWLDGKHVVFGKIIDGLLVMRKIENVPTGPNNKPKLPVVISQCGEM hide sequence

RefSeq Acc Id:	XP_006238834 ⟸ XM_006238772
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZMT9 (UniProtKB/TrEMBL), A6JZN2 (UniProtKB/TrEMBL), A0A8I6A6F0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAVANSSPVNPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGST FHRVIKDFMIQGGFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCS KCDWLDGKHVVFGKIIDGLLVMRKIENVPTGPNNKPKLPVVISQCGEM hide sequence

Ensembl Acc Id:

ENSRNOP00000059353 ⟸ ENSRNOT00000067943

Ensembl Acc Id:

ENSRNOP00000063468 ⟸ ENSRNOT00000064712

Ensembl Acc Id:

ENSRNOP00000088556 ⟸ ENSRNOT00000108155

Ensembl Acc Id:

ENSRNOP00000076976 ⟸ ENSRNOT00000098415

Ensembl Acc Id:

ENSRNOP00000079411 ⟸ ENSRNOT00000112897

RefSeq Acc Id:	NP_001386382 ⟸ NM_001399453
- UniProtKB:	A0A8I5ZMT9 (UniProtKB/TrEMBL), A6JZN2 (UniProtKB/TrEMBL)

Protein Domains

PPIase cyclophilin-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A5R0-F1-model_v2	AlphaFold	D4A5R0	1-176	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693984

Promoter ID:

EPDNEW_R4505

Type:

multiple initiation site

Name:

Ppih_1

Description:

peptidylprolyl isomerase H

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	138,361,727 - 138,361,787	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1564921	AgrOrtholog
BioCyc Gene	G2FUF-40090	BioCyc
Ensembl Genes	ENSRNOG00000008489	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000064712.3	UniProtKB/TrEMBL
	ENSRNOT00000067943.5	UniProtKB/TrEMBL
	ENSRNOT00000098415.1	UniProtKB/TrEMBL
	ENSRNOT00000108155.1	UniProtKB/TrEMBL
	ENSRNOT00000112897.1	UniProtKB/TrEMBL
Gene3D-CATH	2.40.100.10	UniProtKB/TrEMBL
InterPro	Cyclophilin-like_dom	UniProtKB/TrEMBL
	Cyclophilin-type_PPIase	UniProtKB/TrEMBL
	Pep-Pro_Isoase_cyclophilin_CS	UniProtKB/TrEMBL
	PPIase_cyclophilin	UniProtKB/TrEMBL
NCBI Gene	366461	ENTREZGENE
PANTHER	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE	UniProtKB/TrEMBL
	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED	UniProtKB/TrEMBL
Pfam	Pro_isomerase	UniProtKB/TrEMBL
PhenoGen	Ppih	PhenoGen
PIRSF	Peptidylpro_ismrse	UniProtKB/TrEMBL
PRINTS	CSAPPISMRASE	UniProtKB/TrEMBL
PROSITE	CSA_PPIASE_1	UniProtKB/TrEMBL
	CSA_PPIASE_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000008489	RatGTEx
Superfamily-SCOP	SSF50891	UniProtKB/TrEMBL
UniProt	A0A8I5Y5S4_RAT	UniProtKB/TrEMBL
	A0A8I5ZMT9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A6F0	ENTREZGENE, UniProtKB/TrEMBL
	A6JZN2	ENTREZGENE, UniProtKB/TrEMBL
	D3ZUZ9_RAT	UniProtKB/TrEMBL
	D4A5R0_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-01-21	Ppih	peptidylprolyl isomerase H	Ppih	peptidylprolyl isomerase H (cyclophilin H)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-05-05	Ppih	peptidylprolyl isomerase H (cyclophilin H)	RGD1564921	similar to peptidyl prolyl isomerase H	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1564921	similar to peptidyl prolyl isomerase H	RGD1564921_predicted	similar to peptidyl prolyl isomerase H (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1564921_predicted	similar to peptidyl prolyl isomerase H (predicted)	LOC366461	similar to peptidyl prolyl isomerase H	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC366461	similar to peptidyl prolyl isomerase H			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - KEGG (archival)