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Genes search result for Mus musculus
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47 records found for search term Pml
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1557220Pmlpromyelocytic leukemiaEnables SMAD binding activity. Involved in several processes, including defense response to other organism; regulation of macromolecule metabolic process; and signal transduction by p53 class mediator. Acts upstream of or within several processes, including apoptotic signaling pathway; cell surface 95812535958157077Mouse500symbol , old_gene_name , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
737203Fxyd1FXYD domain-containing ion transport regulator 1This gene encodes a member of the FXYD family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The protein encoded by this gene is a plasma membrane substrate for several 73075110330758332Mouse171old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1622820Pram1PML-RAR alpha-regulated adaptor molecule 1Predicted to enable protein kinase binding activity. Acts upstream of or within integrin-mediated signaling pathway and regulation of neutrophil degranulation. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Is expressed in central nervous system; repro173385703033864680Mouse71old_gene_name , name , descriptiongene, protein-coding, VALIDATED [RefSeq]
1312940Ankrd2ankyrin repeat domain 2Enables chromatin binding activity; protein kinase B binding activity; and titin binding activity. Involved in negative regulation of myoblast differentiation. Acts upstream of or within several processes, including negative regulation of myotube differentiation; regulation of intrinsic apoptotic si194202435842033550Mouse114descriptiongene, protein-coding, VALIDATED [RefSeq]
1553098AtrxATRX, chromatin remodelerEnables chromatin binding activity and histone binding activity. Involved in several processes, including DNA damage response, signal transduction by p53 class mediator; cellular response to hydroxyurea; and positive regulation of DNA metabolic process. Acts upstream of or within several processes, X104841221104972978Mouse350descriptiongene, protein-coding, VALIDATED [RefSeq]
1623116Calcoco2calcium binding and coiled-coil domain 2Predicted to enable protein homodimerization activity. Predicted to be involved in positive regulation of autophagosome maturation; response to type II interferon; and xenophagy. Predicted to be located in cytosol; intracellular membrane-bounded organelle; and perinuclear region of cytoplasm. Predic119599019596015362Mouse85descriptiongene, protein-coding, VALIDATED [RefSeq]
1314006Casp8ap2caspase 8 associated protein 2Enables cysteine-type endopeptidase activator activity involved in apoptotic process; identical protein binding activity; and protease binding activity. Acts upstream of or within extrinsic apoptotic signaling pathway via death domain receptors. Predicted to be located in cytoplasm and nucleus. Pred43261546232653271Mouse138descriptiongene, protein-coding, VALIDATED [RefSeq]
732862Chek2checkpoint kinase 2Enables protein kinase activity. Acts upstream of or within several processes, including cellular response to gamma radiation; signal transduction by p53 class mediator; and thymocyte apoptotic process. Predicted to be located in Golgi apparatus and PML body. Pr5110987668111022006Mouse751descriptiongene, protein-coding, VALIDATED [RefSeq]
1314933Chfrcheckpoint with forkhead and ring finger domainsEnables ubiquitin protein ligase activity. Acts upstream of or within several processes, including positive regulation of protein metabolic process; protein destabilization; and protein polyubiquitination. Predicted to be located in PML body. Predicted to be act5110283599110319839Mouse126descriptiongene, protein-coding, VALIDATED [RefSeq]
731386Dapk3death-associated protein kinase 3Enables ATP binding activity and protein serine/threonine kinase activity. Involved in several processes, including cellular response to type II interferon; protein phosphorylation; and regulation of myosin II filament organization. Acts upstream of or within apoptotic signaling pathway. Located in 108101882181029031Mouse233descriptiongene, protein-coding, VALIDATED [RefSeq]
732822DaxxFas death domain-associated proteinEnables histone binding activity and transcription coactivator activity. Involved in several processes, including nucleosome assembly; positive regulation of transcription by RNA polymerase II; and protein localization to chromatin. Acts upstream of or within several processes, including apoptotic s173412837934134564Mouse315descriptiongene, protein-coding, VALIDATED [RefSeq]
1558337Elf4E74 like ETS transcription factor 4Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including lymphocyte proliferation; negative regulation of cytokine production; and positiveX4749992647552009Mouse168descriptiongene, protein-coding, VALIDATED [RefSeq]
15017606Gcnapredicted gene, 52429INVOLVED IN DNA damage response; DNA integrity checkpoint signaling; homologous chromosome pairing at meiosis; FOUND IN condensed chromosome; PML bodyX100739442100749805Mouse14descriptiongene, protein-coding, VALIDATED [RefSeq]
1315132Habp4hyaluronic acid binding protein 4Predicted to enable several functions, including SUMO binding activity; hyaluronic acid binding activity; and translation elongation factor binding activity. Predicted to be involved in PML body organization; cellular response to mechanical stimulus; and regulat136430968064334351Mouse124descriptiongene, protein-coding, VALIDATED [RefSeq]
1312672Hipk1homeodomain interacting protein kinase 1Predicted to enable protein serine/threonine kinase activity; protein tyrosine kinase activity; and transcription corepressor activity. Involved in adherens junction assembly; camera-type eye morphogenesis; and neuron differentiation. Acts upstream of or within several processes, including anterior/3103647131103699210Mouse163descriptiongene, protein-coding, VALIDATED [RefSeq]
731501Hipk3homeodomain interacting protein kinase 3Enables protein serine/threonine kinase activity. Involved in negative regulation of JUN kinase activity; peptidyl-serine phosphorylation; and peptidyl-threonine phosphorylation. Located in PML body and cytoplasm. Is expressed in diaphragm; heart; limb segment; 2104256826104324834Mouse140descriptiongene, protein-coding, VALIDATED [RefSeq]
1318073Ikbkeinhibitor of kappaB kinase epsilonEnables IkappaB kinase activity; K48-linked polyubiquitin modification-dependent protein binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including cellular response to virus; interleukin-17-mediated signaling pathway; and positive regulation of type I 1131182337131207339Mouse209descriptiongene, protein-coding, VALIDATED [RefSeq]
1550848Klhl20kelch-like 20Predicted to enable type II interferon binding activity and ubiquitin-like ligase-substrate adaptor activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including Golgi to endosome transport; proteasome-mediated ubiquitin-depende1160915945160959078Mouse107descriptiongene, protein-coding, VALIDATED [RefSeq]
1550675Lrrc28leucine rich repeat containing 28Predicted to be active in PML body. Orthologous to human LRRC28 (leucine rich repeat containing 28). [provided by Alliance of Genome Resources, Jul 2025]76716315867295084Mouse88descriptiongene, protein-coding, VALIDATED [RefSeq]
1622052Magea10MAGE family member A10Predicted to enable DNA-binding transcription factor binding activity; histone deacetylase binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in PMLX7142547671430464Mouse30descriptiongene, protein-coding, VALIDATED [RefSeq]
1622395Magea2MAGE family member A2Predicted to enable DNA-binding transcription factor binding activity; histone deacetylase binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in PMLX153810197153816309Mouse12descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1622394Magea3MAGE family member A3Predicted to enable DNA-binding transcription factor binding activity and enzyme binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in PML body; cytosol; and endoplasmic reticulum. PreX153731176153742027Mouse37descriptiongene, protein-coding, VALIDATED [RefSeq]
1622393Magea4MAGE family member A4Predicted to enable DNA-binding transcription factor binding activity; histone deacetylase binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in PMLX7126459971266611Mouse41descriptiongene, protein-coding, VALIDATED [RefSeq]
1622392Magea5MAGE family member A5Predicted to enable DNA-binding transcription factor binding activity and enzyme binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in PML body; cytosol; and endoplasmic reticulum. PreX153836057153846147Mouse56descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1618346Mlipmuscular LMNA-interacting proteinEnables lamin binding activity and transcription corepressor activity. Involved in negative regulation of cardiac muscle hypertrophy in response to stress. Acts upstream of or within negative regulation of cardiac muscle hypertrophy and negative regulation of transcription by RNA polymerase II. Loca97700936677260062Mouse80descriptiongene, protein-coding, VALIDATED [RefSeq]
1552838Morc3microrchidia 3Predicted to enable DNA binding activity; methylated histone binding activity; and protein-macromolecule adaptor activity. Acts upstream of or within post-embryonic development. Located in PML body. Is expressed in several structures, including alimentary system169362900993672964Mouse139descriptiongene, protein-coding, VALIDATED [RefSeq]
735478Mre11aMRE11A homolog A, double strand break repair nucleaseEnables nuclease activity. Involved in DNA strand resection involved in replication fork processing; chromosome organization; and double-strand break repair via homologous recombination. Acts upstream of or within several processes, including double-strand break repair; homologous chromosome pairing91469597114748421Mouse318descriptiongene, protein-coding, VALIDATED [RefSeq]
68534Mtormechanistic target of rapamycin kinaseEnables protein serine/threonine kinase activity and ribosome binding activity. Involved in several processes, including 'de novo' pyrimidine nucleobase biosynthetic process; T-helper 1 cell lineage commitment; and TORC2 signaling. Acts upstream of or within several processes, including heart develo4148533039148642142Mouse1704descriptiongene, protein-coding, VALIDATED [RefSeq]
1313053N4bp1NEDD4 binding protein 1Predicted to enable RNA nuclease activity; mRNA binding activity; and ubiquitin binding activity. Involved in cellular response to UV; negative regulation of macromolecule metabolic process; and regulation of innate immune response. Located in PML body; cytosol;88756776487612489Mouse139descriptiongene, protein-coding, VALIDATED [RefSeq]
732723NbnnibrinEnables chromatin-protein adaptor activity and damaged DNA binding activity. Involved in DNA metabolic process and blastocyst growth. Acts upstream of or within intracellular signal transduction; neuroblast proliferation; and neuromuscular process controlling balance. Located in PML41595538815992589Mouse479descriptiongene, protein-coding, VALIDATED [RefSeq]
731685Nr2c1nuclear receptor subfamily 2, group C, member 1Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; histone deacetylase binding activity; and protein homodimerization activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of retinoic acid r109398349194033078Mouse124descriptiongene, protein-coding, VALIDATED [RefSeq]
1331905Nsmce2NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligasePredicted to enable SUMO ligase activity. Predicted to be involved in several processes, including DNA recombination; positive regulation of cell cycle process; and protein sumoylation. Predicted to be located in PML body and chromosome, telomeric region. Predic155924604759473538Mouse159descriptiongene, protein-coding, VALIDATED [RefSeq]
1317274Pias1protein inhibitor of activated STAT 1Enables several functions, including SUMO ligase activity; transcription cis-regulatory region binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including fat cell differentiation; protein sumoylation; and regulation of primary metabolic process. Located96278564862888161Mouse237descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1550389Rnf6ring finger protein (C3H2C3 type) 6Enables DNA binding activity and ubiquitin protein ligase activity. Involved in protein K48-linked ubiquitination and ubiquitin-dependent protein catabolic process. Acts upstream of or within negative regulation of axon extension and positive regulation of DNA-templated transcription. Located in ... (more)5146146003146158267Mouse140descriptiongene, protein-coding, VALIDATED [RefSeq]
734242Rpa2replication protein A2Enables DNA binding activity. Predicted to be involved in several processes, including DNA metabolic process; regulation of cell cycle phase transition; and regulation of double-strand break repair via homologous recombination. Predicted to be located in PML bod4132495671132506057Mouse214descriptiongene, protein-coding, VALIDATED [RefSeq]
1331906RpainRPA interacting proteinPredicted to enable zinc ion binding activity. Predicted to be involved in protein import into nucleus. Predicted to act upstream of or within DNA metabolic process and response to UV. Predicted to be located in PML body; cytoplasm; and fibrillar center. Predict117086040370868759Mouse88descriptiongene, protein-coding, VALIDATED [RefSeq]
733308Senp2SUMO/sentrin specific peptidase 2Enables deSUMOylase activity. Involved in fat cell differentiation and protein desumoylation. Acts upstream of or within several processes, including embryonic placenta development; positive regulation of transcription by RNA polymerase II; and regulation of cell cycle process. Located in nuclear bo162182818221868019Mouse165descriptiongene, protein-coding, VALIDATED [RefSeq]
1614077Simc1SUMO-interacting motifs containing 1Predicted to enable SUMO polymer binding activity and peptidase inhibitor activity. Predicted to be located in PML body and sarcomere. Orthologous to human SIMC1 (SUMO interacting motifs containing 1). [provided by Alliance of Genome Resources, Jul 2025]135465153954699103Mouse60descriptiongene, protein-coding, VALIDATED [RefSeq]
1614178Slf2SMC5-SMC6 complex localization factor 2Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including positive regulation of cellular component organization; positive regulation of double-strand break repair; and protein localization to site of double-strand break. Predicted to be 194490694844972225Mouse95descriptiongene, protein-coding, VALIDATED [RefSeq]
1316719Smc5structural maintenance of chromosomes 5Predicted to enable DNA secondary structure binding activity and single-stranded DNA binding activity. Acts upstream of or within several processes, including internal peptidyl-lysine acetylation; mitotic cell cycle phase transition; and protein localization to chromosome, centromeric region. Locate192318381723251286Mouse178descriptiongene, protein-coding, VALIDATED [RefSeq]
1315808Sumo1small ubiquitin-like modifier 1Predicted to enable enzyme binding activity; potassium channel regulator activity; and protein tag activity. Involved in several processes, including positive regulation of ATPase-coupled calcium transmembrane transporter activity; regulation of cardiac muscle cell contraction; and regulation of pro15967859359709993Mouse260descriptiongene, protein-coding, VALIDATED [RefSeq]
1617602Tdgthymine DNA glycosylaseEnables several functions, including SUMO binding activity; protein kinase C binding activity; and transcription coregulator activity. Involved in base-excision repair; epigenetic regulation of gene expression; and regulation of embryonic development. Acts upstream of or within negative regulation o108246564982486633Mouse193descriptiongene, protein-coding, VALIDATED [RefSeq]
1557333Tdp2tyrosyl-DNA phosphodiesterase 2Predicted to enable several functions, including metal ion binding activity; phosphoric diester hydrolase activity; and single-stranded DNA binding activity. Predicted to be involved in double-strand break repair and neuron development. Predicted to be located in aggresome and nuclear body. Predicte132501564225026136Mouse123descriptiongene, protein-coding, VALIDATED [RefSeq]
736748Tenm2teneurin transmembrane protein 2Enables protein heterodimerization activity and protein homodimerization activity. Predicted to be involved in several processes, including heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; positive regulation of filopodium assembly; and retrograde trans-synaptic signaling113589748337881486Mouse175descriptiongene, protein-coding, VALIDATED [RefSeq]
1319605Top3atopoisomerase (DNA) III alphaPredicted to enable DNA topoisomerase type I (single strand cut, ATP-independent) activity and single-stranded DNA binding activity. Predicted to be involved in DNA metabolic process and chromosome separation. Predicted to be located in PML body. Predicted to be116062901460668099Mouse107descriptiongene, protein-coding, VALIDATED [RefSeq]
1552702Zcchc12zinc finger, CCHC domain containing 12Enables SUMO binding activity and transcription coactivator activity. Acts upstream of or within BMP signaling pathway and positive regulation of transcription by RNA polymerase II. Located in PML body and nuclear speck. Is expressed in several structures, incluX3545955335462817Mouse83descriptiongene, protein-coding, VALIDATED [RefSeq]
1314153Zfp451zinc finger protein 451Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; SUMO ligase activity; and transcription corepressor activity. Predicted to be involved in negative regulation of transcription initiation by RNA polymerase II; negative regulation 13380062233854683Mouse112descriptiongene, protein-coding, VALIDATED [RefSeq]