Top3a (topoisomerase (DNA) III alpha) - Rat Genome Database
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Gene: Top3a (topoisomerase (DNA) III alpha) Mus musculus
Analyze
Symbol: Top3a
Name: topoisomerase (DNA) III alpha
RGD ID: 1319605
MGI Page MGI
Description: Is expressed in brain; female associated reproductive structure; and ureter. Human ortholog(s) of this gene implicated in autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 5. Orthologous to human TOP3A (DNA topoisomerase III alpha); PARTICIPATES IN homologous recombination pathway of double-strand break repair; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DNA topoisomerase 3-alpha; DNA topoisomerase III alpha; MGC106383; Top IIIa; topoisomerase (DNA) 3 alpha; topoisomerase 3 alpha
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391160,629,035 - 60,668,191 (-)NCBIGRCm39mm39
GRCm39 Ensembl1160,630,884 - 60,668,191 (-)Ensembl
GRCm381160,738,209 - 60,777,365 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1160,740,058 - 60,777,365 (-)EnsemblGRCm38mm10GRCm38
MGSCv371160,553,561 - 60,590,867 (-)NCBIGRCm37mm9NCBIm37
MGSCv361160,556,254 - 60,593,560 (-)NCBImm8
Celera1165,000,916 - 65,014,847 (-)NCBICelera
Cytogenetic Map11B2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromosome  (IEA)
mitochondrion  (IEA)
nucleoplasm  (TAS)
nucleus  (IBA)
PML body  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:9448276   PMID:9540825   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11327713   PMID:12477932   PMID:12520002   PMID:14610273   PMID:16033648  
PMID:16141072   PMID:16141073   PMID:16602821   PMID:17273973   PMID:18287559   PMID:18799693   PMID:20360068   PMID:21267068   PMID:21873635   PMID:30595499   PMID:32325033  


Genomics

Comparative Map Data
Top3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391160,629,035 - 60,668,191 (-)NCBIGRCm39mm39
GRCm39 Ensembl1160,630,884 - 60,668,191 (-)Ensembl
GRCm381160,738,209 - 60,777,365 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1160,740,058 - 60,777,365 (-)EnsemblGRCm38mm10GRCm38
MGSCv371160,553,561 - 60,590,867 (-)NCBIGRCm37mm9NCBIm37
MGSCv361160,556,254 - 60,593,560 (-)NCBImm8
Celera1165,000,916 - 65,014,847 (-)NCBICelera
Cytogenetic Map11B2NCBI
TOP3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1718,271,428 - 18,315,007 (-)EnsemblGRCh38hg38GRCh38
GRCh381718,269,958 - 18,314,996 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371718,174,742 - 18,218,308 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361718,117,960 - 18,159,046 (-)NCBINCBI36hg18NCBI36
Build 341718,117,959 - 18,159,046NCBI
Celera1719,118,328 - 19,159,392 (-)NCBI
Cytogenetic Map17p11.2NCBI
HuRef1717,930,468 - 17,971,853 (-)NCBIHuRef
CHM1_11718,183,522 - 18,227,165 (-)NCBICHM1_1
Top3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21045,419,219 - 45,457,356 (-)NCBI
Rnor_6.0 Ensembl1046,981,958 - 47,018,537 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01046,980,646 - 47,018,728 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01046,753,640 - 46,790,892 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41046,886,319 - 46,923,435 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11046,899,953 - 46,910,769 (-)NCBI
Celera1044,674,374 - 44,711,934 (-)NCBICelera
Cytogenetic Map10q22NCBI
Top3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547811,015,378 - 11,045,717 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547811,015,378 - 11,045,717 (+)NCBIChiLan1.0ChiLan1.0
TOP3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11737,897,009 - 37,940,446 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1737,897,037 - 37,936,135 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01732,814,448 - 32,858,076 (-)NCBIMhudiblu_PPA_v0panPan3
TOP3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl541,263,017 - 41,290,100 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1541,262,820 - 41,290,101 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Top3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049367411,809,371 - 1,838,711 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TOP3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1260,443,731 - 60,469,040 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11260,443,592 - 60,468,968 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TOP3A
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11617,315,466 - 17,358,863 (-)NCBI
ChlSab1.1 Ensembl1617,316,048 - 17,358,580 (-)Ensembl
Top3a
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248493,159,432 - 3,196,235 (+)NCBI

Position Markers
Top3a  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B2UniSTS
cM Map11 UniSTS
AB006074  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381160,740,300 - 60,740,431UniSTSGRCm38
MGSCv371160,553,802 - 60,553,933UniSTSGRCm37
Celera1165,001,157 - 65,001,288UniSTS
Cytogenetic Map11B2UniSTS
Whitehead/MRC_RH11800.12UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11330000060800000Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11330000063000000Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11330000072800000Mouse
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11890000061500000Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111160000068600000Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111180000066100000Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1231863768609504Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111231863768609504Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111231863768609504Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1231863768609504Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1231863768609504Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111231863768609504Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1231863768609504Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1231863768609504Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1231863768609504Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111231863768609504Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111231863768609504Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111231863769794121Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111710617567187585Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111783196668609504Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112827504662275149Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112867832062678320Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112881775462817873Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113111738265117382Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113220975066209867Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113568778969794161Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113661246070618665Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113672273870723028Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113719011571190238Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113812528972125383Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114236579176365904Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114236579176365904Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114473921176963931Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4141084Spqq1_msperm quality QTL 1 (mouse)Not determined5417484463428696Mouse
1302186Blmpf2_mbleomycin-induced pulmonary fibrosis 2 (mouse)Not determined115417484467187585Mouse
4142148Ckdbp2_mchronic kidney disease blood pressure locus 2 (mouse)Not determined115419011565213015Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5539415972319101Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115859972974863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
11532697Sluc36_msusceptibility to lung cancer 36 (mouse)115936579169591873Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1016
Count of miRNA genes:473
Interacting mature miRNAs:554
Transcripts:ENSMUST00000002891, ENSMUST00000102668, ENSMUST00000117743, ENSMUST00000120417, ENSMUST00000124799, ENSMUST00000130068
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000002891   ⟹   ENSMUSP00000002891
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,740,058 - 60,777,365 (-)Ensembl
RefSeq Acc Id: ENSMUST00000102668   ⟹   ENSMUSP00000099729
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,741,891 - 60,777,265 (-)Ensembl
RefSeq Acc Id: ENSMUST00000117743   ⟹   ENSMUSP00000113057
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,740,059 - 60,777,287 (-)Ensembl
RefSeq Acc Id: ENSMUST00000120417   ⟹   ENSMUSP00000113653
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,742,234 - 60,777,264 (-)Ensembl
RefSeq Acc Id: ENSMUST00000124799
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,749,457 - 60,752,678 (-)Ensembl
RefSeq Acc Id: ENSMUST00000130068   ⟹   ENSMUSP00000115727
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1160,761,732 - 60,777,299 (-)Ensembl
RefSeq Acc Id: NM_009410   ⟹   NP_033436
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391160,629,035 - 60,668,191 (-)NCBI
GRCm381160,738,209 - 60,777,365 (-)NCBI
MGSCv371160,553,561 - 60,590,867 (-)RGD
Celera1165,000,916 - 65,014,837 (-)ENTREZGENE
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036156625   ⟹   XP_036012518
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391160,630,299 - 60,668,074 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_033436   ⟸   NM_009410
- UniProtKB: O70157 (UniProtKB/Swiss-Prot),   Q5NCT2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000115727   ⟸   ENSMUST00000130068
RefSeq Acc Id: ENSMUSP00000113653   ⟸   ENSMUST00000120417
RefSeq Acc Id: ENSMUSP00000002891   ⟸   ENSMUST00000002891
RefSeq Acc Id: ENSMUSP00000113057   ⟸   ENSMUST00000117743
RefSeq Acc Id: ENSMUSP00000099729   ⟸   ENSMUST00000102668
RefSeq Acc Id: XP_036012518   ⟸   XM_036156625
- Peptide Label: isoform X1
Protein Domains
Toprim

Promoters
RGD ID:6822172
Promoter ID:MM_KWN:7741
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000101115,   ENSMUST00000117743,   ENSMUST00000120417,   NM_001085440,   NM_175491,   OTTMUST00000017705,   OTTMUST00000017707,   UC007JGM.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361160,590,121 - 60,595,002 (+)MPROMDB
RGD ID:8674892
Promoter ID:EPDNEW_M15477
Type:initiation region
Name:Top3a_1
Description:Mus musculus topoisomerase III alpha , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15478  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381160,777,273 - 60,777,333EPDNEW
RGD ID:8674894
Promoter ID:EPDNEW_M15478
Type:multiple initiation site
Name:Top3a_2
Description:Mus musculus topoisomerase III alpha , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15477  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381160,777,442 - 60,777,502EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1197527 AgrOrtholog
Ensembl Genes ENSMUSG00000002814 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000002891 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000099729 UniProtKB/TrEMBL
  ENSMUSP00000113057 UniProtKB/TrEMBL
  ENSMUSP00000113653 UniProtKB/TrEMBL
  ENSMUSP00000115727 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000002891 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000102668 UniProtKB/TrEMBL
  ENSMUST00000117743 UniProtKB/TrEMBL
  ENSMUST00000120417 UniProtKB/TrEMBL
  ENSMUST00000130068 UniProtKB/TrEMBL
Gene3D-CATH 1.10.290.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.460.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.70.20.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Topo_IA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Topo_IA_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Topo_IA_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Topo_IA_cen UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Topo_IA_cen_sub1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Topo_IA_cen_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Topo_IA_cen_sub3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Topo_IA_core_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Topo_IA_DNA-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Topo_IA_Znf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TOPRIM_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TOPRIM_TopoIII UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_GRF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:21975 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1197527 ENTREZGENE
NCBI Gene 21975 ENTREZGENE
PANTHER PTHR11390 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Topoisom_bac UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Toprim UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C4_Topoisom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-GRF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Top3a PhenoGen
PRINTS PRTPISMRASEI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TOPOISOMERASE_I_PROK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TOPRIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART TOP1Ac UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TOP1Bc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TOPRIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56712 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B0QZI1_MOUSE UniProtKB/TrEMBL
  O70157 ENTREZGENE
  Q3TBE3_MOUSE UniProtKB/TrEMBL
  Q3TPE4_MOUSE UniProtKB/TrEMBL
  Q3V3P1_MOUSE UniProtKB/TrEMBL
  Q5NCT0_MOUSE UniProtKB/TrEMBL
  Q5NCT1_MOUSE UniProtKB/TrEMBL
  Q5NCT2 ENTREZGENE, UniProtKB/TrEMBL
  Q8CDI8_MOUSE UniProtKB/TrEMBL
  TOP3A_MOUSE UniProtKB/Swiss-Prot