Csnk2a2 (casein kinase 2 alpha 2) - Rat Genome Database

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Gene: Csnk2a2 (casein kinase 2 alpha 2) Rattus norvegicus
Analyze
Symbol: Csnk2a2
Name: casein kinase 2 alpha 2
RGD ID: 1306882
Description: Predicted to enable protein serine/threonine kinase activity. Involved in cerebral cortex development; liver regeneration; and spermatogenesis. Located in acrosomal vesicle and chromatin. Orthologous to human CSNK2A2 (casein kinase 2 alpha 2); PARTICIPATES IN E-cadherin signaling pathway; mitochondrial autophagy pathway; nuclear factor kappa B signaling pathway; INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: casein kinase 2, alpha prime polypeptide; casein kinase II subunit alpha'; casein kinase II, alpha 2, polypeptide; LOC307641
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8199,562,340 - 9,602,136 (+)NCBIGRCr8
mRatBN7.2199,556,443 - 9,596,080 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl199,556,260 - 9,596,080 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx199,521,860 - 9,561,150 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01910,288,686 - 10,327,976 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0199,575,016 - 9,614,306 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0199,972,537 - 10,012,043 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl199,972,537 - 10,012,043 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0199,956,494 - 9,996,397 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41910,015,369 - 10,054,662 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11910,020,174 - 10,054,722 (+)NCBI
Celera199,448,494 - 9,487,786 (+)NCBICelera
Cytogenetic Map19p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
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Original Reference(s)
Csnk2a2RatOxygen-Induced Retinopathy  ISOCsnk2a2 (Mus musculus)11565123 RGD 
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Original Reference(s)
Csnk2a2RatBardet-Biedl syndrome  ISOCSNK2A2 (Homo sapiens)8554872ClinVar Annotator: match by term: Bardet-Biedl syndromeClinVarPMID:11285252 more ...
Csnk2a2RatChromosome 16q12 Duplication Syndrome  ISOCSNK2A2 (Homo sapiens)8554872ClinVar Annotator: match by term: Chromosome 16q12 duplication syndromeClinVarPMID:25741868
Csnk2a2Ratdevelopmental and epileptic encephalopathy  ISOCSNK2A2 (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathyClinVarPMID:11285252 more ...
Csnk2a2Ratearly infantile epileptic encephalopathy  ISOCSNK2A2 (Homo sapiens)8554872ClinVar Annotator: match by term: Early infantile epileptic encephalopathyClinVarPMID:11285252 more ...
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Original Reference(s)
Csnk2a2RatSkin Neoplasms  ISOCSNK2A2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:18572023
Csnk2a2Ratsquamous cell carcinoma  ISOCSNK2A2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:18572023
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Original Reference(s)
Csnk2a2Ratmale infertility  ISSCsnk2a2 (Mus musculus)13592920 MouseDO 

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Original Reference(s)
Csnk2a2Rat(-)-epigallocatechin 3-gallate multiple interactionsISOCSNK2A2 (Homo sapiens)6480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of CSNK2A2 mRNACTDPMID:22079256
Csnk2a2Rat1,2-dimethylhydrazine multiple interactionsISOCsnk2a2 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CSNK2A2 mRNACTDPMID:22206623
Csnk2a2Rat17alpha-ethynylestradiol increases expressionISOCsnk2a2 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of CSNK2A2 mRNACTDPMID:17942748
Csnk2a2Rat17alpha-ethynylestradiol multiple interactionsISOCsnk2a2 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CSNK2A2 mRNACTDPMID:17942748
Csnk2a2Rat17beta-estradiol affects expressionISOCsnk2a2 (Mus musculus)6480464Estradiol affects the expression of CSNK2A2 mRNACTDPMID:15721199
Csnk2a2Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISOCSNK2A2 (Homo sapiens)64804642 more ...CTDPMID:31675489
Csnk2a2Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOCsnk2a2 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CSNK2A2 mRNACTDPMID:17942748
Csnk2a2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOCSNK2A2 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in decreased expression of CSNK2A2 mRNACTDPMID:26238291
Csnk2a2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOCsnk2a2 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of CSNK2A2 mRNACTDPMID:21570461
Csnk2a2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOCsnk2a2 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of CSNK2A2 mRNACTDPMID:17942748
Csnk2a2Rat2-hydroxypropanoic acid decreases expressionISOCSNK2A2 (Homo sapiens)6480464Lactic Acid results in decreased expression of CSNK2A2 mRNACTDPMID:30851411
Csnk2a2Rat2-methylcholine affects expressionISOCSNK2A2 (Homo sapiens)6480464beta-methylcholine affects the expression of CSNK2A2 mRNACTDPMID:21179406
Csnk2a2Rat3,3',5,5'-tetrabromobisphenol A decreases expressionISOCSNK2A2 (Homo sapiens)6480464tetrabromobisphenol A results in decreased expression of CSNK2A2 proteinCTDPMID:31675489
Csnk2a2Rat4,4'-sulfonyldiphenol decreases expressionISOCsnk2a2 (Mus musculus)6480464bisphenol S results in decreased expression of CSNK2A2 mRNACTDPMID:39298647
Csnk2a2Rat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of CSNK2A2 mRNACTDPMID:36041667
Csnk2a2Rat5-aza-2'-deoxycytidine increases expressionISOCsnk2a2 (Mus musculus)6480464Decitabine results in increased expression of CSNK2A2 mRNACTDPMID:27915011
Csnk2a2Rat5-aza-2'-deoxycytidine increases expressionISOCSNK2A2 (Homo sapiens)6480464Decitabine results in increased expression of CSNK2A2 mRNA and Decitabine results in increased expression of CSNK2A2 proteinCTDPMID:19027835
Csnk2a2Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of CSNK2A2 mRNACTDPMID:30047161
Csnk2a2Rataflatoxin B1 increases expressionISOCsnk2a2 (Mus musculus)6480464Aflatoxin B1 results in increased expression of CSNK2A2 mRNACTDPMID:19770486
Csnk2a2Ratall-trans-retinoic acid decreases expressionISOCSNK2A2 (Homo sapiens)6480464Tretinoin results in decreased expression of CSNK2A2 mRNACTDPMID:33167477

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Biological Process
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Original Reference(s)
Csnk2a2Ratcerebral cortex development  IEP 11565823 RGD 
Csnk2a2RatDNA damage response involved_inIBAPANTHER:PTN000621946 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Csnk2a2Ratdouble-strand break repair involved_inISOCSNK2A2 (Homo sapiens)1624291 PMID:22325354RGDPMID:22325354
Csnk2a2Ratdouble-strand break repair involved_inIEAUniProtKB:P19784 and ensembl:ENSP000002625061600115GO_REF:0000107EnsemblGO_REF:0000107
Csnk2a2Ratliver regeneration  IEP 11565141 RGD 
Csnk2a2Ratnegative regulation of proteasomal ubiquitin-dependent protein catabolic process involved_inISOCSNK2A2 (Homo sapiens)1624291UniProtKB:P25686 more ...RGDPMID:28031292
Csnk2a2Ratnegative regulation of proteasomal ubiquitin-dependent protein catabolic process involved_inIEAUniProtKB:P19784 and ensembl:ENSP000002625061600115GO_REF:0000107EnsemblGO_REF:0000107
Csnk2a2Ratpositive regulation of protein targeting to mitochondrion involved_inISOCSNK2A2 (Homo sapiens)9068941 PMID:24912190ParkinsonsUK-UCLPMID:24912190
Csnk2a2Ratprotein phosphorylation acts_upstream_of_or_withinISOCsnk2a2 (Mus musculus)1624291 PMID:14644449 more ...RGDPMID:14644449 more ...
Csnk2a2Ratregulation of cell cycle acts_upstream_of_or_withinISOCsnk2a2 (Mus musculus)1624291 PMID:10094394 and PMID:9694889RGDPMID:10094394 and PMID:9694889
Csnk2a2Ratregulation of chromosome separation involved_inISOCSNK2A2 (Homo sapiens)1624291 PMID:11704824RGDPMID:11704824
Csnk2a2Ratregulation of chromosome separation involved_inIEAUniProtKB:P19784 and ensembl:ENSP000002625061600115GO_REF:0000107EnsemblGO_REF:0000107
Csnk2a2Ratregulation of chromosome separation involved_inIBAPANTHER:PTN002779294 and UniProtKB:P197841600115GO_REF:0000033GO_CentralGO_REF:0000033
Csnk2a2Ratregulation of mitophagy involved_inISOCSNK2A2 (Homo sapiens)9068941 PMID:24912190ParkinsonsUK-UCLPMID:24912190
Csnk2a2Ratspermatogenesis  IEP 11565138 RGD 
Csnk2a2Ratspermatogenesis acts_upstream_of_or_withinISOCsnk2a2 (Mus musculus)1624291MGI:2182135 PMID:10471512 and PMID:12950107RGDPMID:10471512 and PMID:12950107
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Cellular Component
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Original Reference(s)
Csnk2a2Ratacrosomal vesicle  IDA 11565138 RGD 
Csnk2a2Ratchromatin  IDA 11565845 RGD 
Csnk2a2Ratcytosol is_active_inIBAFB:FBgn0264492 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Csnk2a2Ratnucleus located_inIEAUniRule:UR0019037931600115GO_REF:0000104UniProtGO_REF:0000104
Csnk2a2Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Csnk2a2Ratnucleus located_inIEAUniProtKB:P19784 and ensembl:ENSP000002625061600115GO_REF:0000107EnsemblGO_REF:0000107
Csnk2a2Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Csnk2a2Ratnucleus located_inISOCSNK2A2 (Homo sapiens)1624291 PMID:21282530RGDPMID:21282530
Csnk2a2Ratnucleus is_active_inIBAFB:FBgn0264492 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Csnk2a2RatPcG protein complex located_inISOCSNK2A2 (Homo sapiens)1624291 PMID:21282530RGDPMID:21282530
Csnk2a2RatPcG protein complex located_inIEAUniProtKB:P19784 and ensembl:ENSP000002625061600115GO_REF:0000107EnsemblGO_REF:0000107
Csnk2a2Ratprotein kinase CK2 complex part_ofIBAFB:FBgn0264492 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
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Molecular Function
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Csnk2a2RatATP binding enablesIEAUniRule:UR001503341 and UniRule:UR0019037931600115GO_REF:0000104UniProtGO_REF:0000104
Csnk2a2RatATP binding enablesIEAInterPro:IPR000719 and InterPro:IPR0174411600115GO_REF:0000002InterProGO_REF:0000002
Csnk2a2RatATP binding enablesIEAUniProtKB-KW:KW-00671600115GO_REF:0000043UniProtGO_REF:0000043
Csnk2a2Ratkinase activity enablesIEAUniProtKB-KW:KW-04181600115GO_REF:0000043UniProtGO_REF:0000043
Csnk2a2Ratnucleotide binding enablesIEAUniRule:UR0015033411600115GO_REF:0000104UniProtGO_REF:0000104
Csnk2a2Ratnucleotide binding enablesIEAUniProtKB-KW:KW-05471600115GO_REF:0000043UniProtGO_REF:0000043
Csnk2a2Ratprotein binding enablesISOCSNK2A2 (Homo sapiens)1624291UniProtKB:O60282 more ...RGDPMID:10094392 more ...
Csnk2a2Ratprotein binding enablesISOCsnk2a2 (Mus musculus)1624291PR:Q8CH19 PMID:19273531RGDPMID:19273531
Csnk2a2Ratprotein kinase activity enablesISOCsnk2a2 (Mus musculus)1624291 PMID:27998980RGDPMID:27998980
Csnk2a2Ratprotein kinase activity enablesIEAInterPro:IPR000719 and InterPro:IPR0082711600115GO_REF:0000002InterProGO_REF:0000002
Csnk2a2Ratprotein serine kinase activity enablesIEAUniRule:UR0019037931600115GO_REF:0000104UniProtGO_REF:0000104
Csnk2a2Ratprotein serine/threonine kinase activity enablesISOCSNK2A2 (Homo sapiens)1624291UniProtKB:P67870 more ...RGDPMID:20545769 more ...
Csnk2a2Ratprotein serine/threonine kinase activity enablesIEAInterPro:IPR0452161600115GO_REF:0000002InterProGO_REF:0000002
Csnk2a2Ratprotein serine/threonine kinase activity enablesISOCsnk2a2 (Mus musculus)1624291 PMID:18496528 and PMID:9694889RGDPMID:18496528 and PMID:9694889
Csnk2a2Ratprotein serine/threonine kinase activity enablesIEAUniRule:UR0019037931600115GO_REF:0000104UniProtGO_REF:0000104
Csnk2a2Ratprotein serine/threonine kinase activity enablesIEAUniProtKB:P19784 and ensembl:ENSP000002625061600115GO_REF:0000107EnsemblGO_REF:0000107
Csnk2a2Ratprotein serine/threonine kinase activity enablesIEAUniProtKB-KW:KW-07231600115GO_REF:0000043UniProtGO_REF:0000043
Csnk2a2Ratprotein serine/threonine kinase activity enablesIBAFB:FBgn0264492 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Csnk2a2Rattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
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RGD Manual Annotations


  
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Original Reference(s)
Csnk2a2Ratmitochondrial autophagy pathway   ISOCSNK2A2 (Homo sapiens)10400888 RGD 

Imported Annotations - KEGG (archival)

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Csnk2a2Ratmeasles pathway  IEA 6907045 KEGGrno:05162
Csnk2a2Ratribosome biogenesis pathway   IEA 6907045 KEGGrno:03008
Csnk2a2RatWnt signaling pathway  IEA 6907045 KEGGrno:04310

Imported Annotations - PID (archival)

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Csnk2a2RatE-cadherin signaling pathway  ISOCSNK2A2 (Homo sapiens)6484113 PIDPID:200124
Csnk2a2Ratnuclear factor kappa B signaling pathway   ISOCSNK2A2 (Homo sapiens)6484113 PIDPID:200021

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#
Reference Title
Reference Citation
1. Differential localization of alpha' and beta subunits of protein kinase CK2 during rat spermatogenesis. Alvarado-Diaz CP, etal., Cell Tissue Res. 2009 Oct;338(1):139-49. doi: 10.1007/s00441-009-0847-1. Epub 2009 Aug 27.
2. Regulation of protein kinase CK2 isoform expression during rat brain development. Diaz-Nido J, etal., Cell Mol Biol Res. 1994;40(5-6):581-5.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Expression of protein kinase CK2 in astroglial cells of normal and neovascularized retina. Kramerov AA, etal., Am J Pathol. 2006 May;168(5):1722-36.
6. Role of autophosphorylation in regulation of protein kinase CK2 from rat neuronal chromatin. Kulikova OG and Reikhardt BA, Biochemistry (Mosc). 1998 Dec;63(12):1400-6.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Changes in the activity of nuclear protein kinase CK2 during rat liver regeneration. Pancetti F, etal., Biochem Biophys Res Commun. 1996 Jan 5;218(1):35-9.
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
11. GOA pipeline RGD automated data pipeline
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Comprehensive gene review and curation RGD comprehensive gene curation
14. The tight association of protein kinase CK2 with plasma membranes is mediated by a specific domain of its regulatory beta-subunit. Sarrouilhe D, etal., Biochim Biophys Acta. 1998 Jun 22;1403(2):199-210.
15. Selective removal of mitochondria via mitophagy: distinct pathways for different mitochondrial stresses. Wei H, etal., Biochim Biophys Acta. 2015 Oct;1853(10 Pt B):2784-90. doi: 10.1016/j.bbamcr.2015.03.013. Epub 2015 Apr 1.
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PMID:9694889   PMID:9930856   PMID:11704824   PMID:11972058   PMID:12477932   PMID:14644449   PMID:18496528   PMID:21282530   PMID:21630459   PMID:22206666   PMID:24912190   PMID:25931508  
PMID:27998980   PMID:28031292   PMID:31505169  



Csnk2a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8199,562,340 - 9,602,136 (+)NCBIGRCr8
mRatBN7.2199,556,443 - 9,596,080 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl199,556,260 - 9,596,080 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx199,521,860 - 9,561,150 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01910,288,686 - 10,327,976 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0199,575,016 - 9,614,306 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0199,972,537 - 10,012,043 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl199,972,537 - 10,012,043 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0199,956,494 - 9,996,397 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41910,015,369 - 10,054,662 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11910,020,174 - 10,054,722 (+)NCBI
Celera199,448,494 - 9,487,786 (+)NCBICelera
Cytogenetic Map19p13NCBI
CSNK2A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381658,157,907 - 58,198,106 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1658,157,907 - 58,198,106 (-)EnsemblGRCh38hg38GRCh38
GRCh371658,191,811 - 58,232,010 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361656,749,312 - 56,789,283 (-)NCBINCBI36Build 36hg18NCBI36
Build 341656,749,314 - 56,789,283NCBI
Celera1642,691,263 - 42,731,230 (-)NCBICelera
Cytogenetic Map16q21NCBI
HuRef1644,059,729 - 44,099,930 (-)NCBIHuRef
CHM1_11659,598,846 - 59,638,724 (-)NCBICHM1_1
T2T-CHM13v2.01663,953,540 - 63,993,732 (-)NCBIT2T-CHM13v2.0
Csnk2a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39896,172,724 - 96,215,505 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl896,172,724 - 96,216,667 (-)EnsemblGRCm39 Ensembl
GRCm38895,446,096 - 95,488,868 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl895,446,096 - 95,490,039 (-)EnsemblGRCm38mm10GRCm38
MGSCv37897,969,996 - 98,012,720 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36898,337,101 - 98,377,919 (-)NCBIMGSCv36mm8
Celera899,760,768 - 99,802,427 (-)NCBICelera
Cytogenetic Map8C5- D1NCBI
cM Map847.12NCBI
Csnk2a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543315,674,116 - 15,718,894 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543315,677,788 - 15,718,894 (-)NCBIChiLan1.0ChiLan1.0
CSNK2A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21867,620,768 - 67,660,961 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11673,541,651 - 73,581,859 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01638,426,399 - 38,466,575 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11657,557,262 - 57,596,218 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1657,557,270 - 57,596,218 (-)Ensemblpanpan1.1panPan2
CSNK2A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1258,361,328 - 58,441,701 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl258,360,838 - 58,432,371 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha254,991,254 - 55,071,046 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0258,899,781 - 58,979,588 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl258,899,298 - 58,971,571 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1255,731,413 - 55,811,164 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0256,739,015 - 56,818,751 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0257,631,725 - 57,711,511 (+)NCBIUU_Cfam_GSD_1.0
Csnk2a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934949,513,855 - 49,558,667 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647510,033,717 - 10,075,511 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647510,030,408 - 10,073,576 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CSNK2A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl619,976,930 - 20,016,923 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1619,975,030 - 20,016,768 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2617,998,939 - 18,074,082 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CSNK2A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1544,093,320 - 44,133,352 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl544,093,215 - 44,133,335 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604732,045,388 - 32,085,772 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Csnk2a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474628,012,556 - 28,060,413 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474628,012,543 - 28,064,610 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Csnk2a2
168 total Variants

Predicted Target Of
Summary Value
Count of predictions:312
Count of miRNA genes:188
Interacting mature miRNAs:228
Transcripts:ENSRNOT00000016386
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 17 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131963836Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
631681Cm12Cardiac mass QTL 123.330.00053heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)19128982497Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127355345Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124688055Rat

1 to 10 of 17 rows
RH132275  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2199,594,284 - 9,594,478 (+)MAPPERmRatBN7.2
Rnor_6.01910,010,248 - 10,010,441NCBIRnor6.0
Rnor_5.0199,994,602 - 9,994,795UniSTSRnor5.0
RGSC_v3.41910,052,867 - 10,053,060UniSTSRGSC3.4
Celera199,485,991 - 9,486,184UniSTS
RH 3.4 Map1993.0UniSTS
Cytogenetic Map19p13UniSTS
RH134385  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2199,576,342 - 9,576,537 (+)MAPPERmRatBN7.2
Rnor_6.0199,992,306 - 9,992,500NCBIRnor6.0
Rnor_5.0199,976,660 - 9,976,854UniSTSRnor5.0
RGSC_v3.41910,034,925 - 10,035,119UniSTSRGSC3.4
Celera199,468,048 - 9,468,242UniSTS
RH 3.4 Map1993.39UniSTS
Cytogenetic Map19p13UniSTS
BE107780  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8199,584,378 - 9,584,536 (+)Marker Load Pipeline
mRatBN7.2199,578,322 - 9,578,480 (+)MAPPERmRatBN7.2
Rnor_6.0199,994,286 - 9,994,443NCBIRnor6.0
Rnor_5.0199,978,640 - 9,978,797UniSTSRnor5.0
RGSC_v3.41910,036,905 - 10,037,062UniSTSRGSC3.4
Celera199,470,028 - 9,470,185UniSTS
RH 3.4 Map1990.3UniSTS
Cytogenetic Map19p13UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000016386   ⟹   ENSRNOP00000016386
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl199,556,260 - 9,596,080 (+)Ensembl
Rnor_6.0 Ensembl199,972,537 - 10,012,043 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107442   ⟹   ENSRNOP00000097267
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl199,556,260 - 9,596,080 (+)Ensembl
RefSeq Acc Id: NM_001107409   ⟹   NP_001100879
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,562,716 - 9,602,136 (+)NCBI
mRatBN7.2199,556,655 - 9,596,080 (+)NCBI
Rnor_6.0199,972,537 - 10,012,043 (+)NCBI
Rnor_5.0199,956,494 - 9,996,397 (+)NCBI
RGSC_v3.41910,015,369 - 10,054,662 (+)RGD
Celera199,448,494 - 9,487,786 (+)RGD
Sequence:
RefSeq Acc Id: XM_039097690   ⟹   XP_038953618
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,562,340 - 9,602,133 (+)NCBI
mRatBN7.2199,556,443 - 9,596,077 (+)NCBI
RefSeq Acc Id: XM_039097691   ⟹   XP_038953619
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,562,591 - 9,602,133 (+)NCBI
mRatBN7.2199,556,443 - 9,596,077 (+)NCBI
RefSeq Acc Id: XM_039097692   ⟹   XP_038953620
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,562,340 - 9,602,133 (+)NCBI
mRatBN7.2199,556,443 - 9,596,077 (+)NCBI
RefSeq Acc Id: XM_039097693   ⟹   XP_038953621
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,562,592 - 9,602,133 (+)NCBI
mRatBN7.2199,556,443 - 9,596,077 (+)NCBI
RefSeq Acc Id: XM_039097694   ⟹   XP_038953622
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,562,340 - 9,602,133 (+)NCBI
mRatBN7.2199,556,443 - 9,596,077 (+)NCBI
RefSeq Acc Id: XM_039097695   ⟹   XP_038953623
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,562,861 - 9,602,133 (+)NCBI
mRatBN7.2199,556,887 - 9,596,077 (+)NCBI
RefSeq Acc Id: XM_063277979   ⟹   XP_063134049
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,562,342 - 9,602,133 (+)NCBI
RefSeq Acc Id: XM_063277980   ⟹   XP_063134050
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,562,341 - 9,602,133 (+)NCBI
RefSeq Acc Id: XM_063277981   ⟹   XP_063134051
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8199,562,827 - 9,600,452 (+)NCBI
1 to 5 of 12 rows
1 to 5 of 12 rows
RefSeq Acc Id: NP_001100879   ⟸   NM_001107409
- UniProtKB: A6JY05 (UniProtKB/TrEMBL),   B4F7A9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000016386   ⟸   ENSRNOT00000016386
RefSeq Acc Id: XP_038953619   ⟸   XM_039097691
- Peptide Label: isoform X2
- UniProtKB: B4F7A9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038953618   ⟸   XM_039097690
- Peptide Label: isoform X1
- UniProtKB: B4F7A9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038953620   ⟸   XM_039097692
- Peptide Label: isoform X3
- UniProtKB: B4F7A9 (UniProtKB/TrEMBL)
Protein kinase

Name Modeler Protein Id AA Range Protein Structure
AF-B4F7A9-F1-model_v2 AlphaFold B4F7A9 1-350 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 27 of 27 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-6533 BioCyc
Ensembl Genes ENSRNOG00000011933 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016386.8 UniProtKB/TrEMBL
  ENSRNOT00000107442.1 UniProtKB/TrEMBL
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro CK2_alpha UniProtKB/TrEMBL
  Kinase-like_dom UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
KEGG Report rno:307641 UniProtKB/TrEMBL
NCBI Gene 307641 ENTREZGENE
PANTHER CASEIN KINASE II SUBUNIT ALPHA UniProtKB/TrEMBL
  PTHR24054 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PhenoGen Csnk2a2 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011933 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
UniProt A0A8I6AW60_RAT UniProtKB/TrEMBL
  A6JY05 ENTREZGENE, UniProtKB/TrEMBL
  B4F7A9 ENTREZGENE, UniProtKB/TrEMBL
  F7FH41_RAT UniProtKB/TrEMBL
1 to 27 of 27 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-27 Csnk2a2  casein kinase 2 alpha 2  Csnk2a2  casein kinase 2, alpha prime polypeptide  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-03 Csnk2a2  casein kinase 2, alpha prime polypeptide  Csnk2a2_predicted  casein kinase II, alpha 2, polypeptide (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Csnk2a2_predicted  casein kinase II, alpha 2, polypeptide (predicted)      Symbol and Name status set to approved 70820 APPROVED