Gabbr1 (gamma-aminobutyric acid type B receptor subunit 1) - Rat Genome Database

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Gene: Gabbr1 (gamma-aminobutyric acid type B receptor subunit 1) Rattus norvegicus
Analyze
Symbol: Gabbr1
Name: gamma-aminobutyric acid type B receptor subunit 1
RGD ID: 621537
Description: Enables G protein-coupled GABA receptor activity; extracellular matrix protein binding activity; and protein heterodimerization activity. Involved in several processes, including negative regulation of adenylate cyclase activity; neuron-glial cell signaling; and regulation of secretion. Acts upstream of or within adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Located in several cellular components, including axolemma; dendrite; and synaptic vesicle. Part of GABA receptor complex. Is active in GABA-ergic synapse; glutamatergic synapse; and synaptic membrane. Used to study alcohol dependence and visual epilepsy. Biomarker of hypertension and visual epilepsy. Human ortholog(s) of this gene implicated in alcohol dependence; amphetamine abuse; cocaine dependence; heroin dependence; and nicotine dependence. Orthologous to human GABBR1 (gamma-aminobutyric acid type B receptor subunit 1); INTERACTS WITH 17beta-estradiol 3-benzoate; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GABA-B receptor 1; GABA-B-R1; GABA-BR1; GABABR1; gamma-aminobutyric acid (GABA) B receptor 1; gamma-aminobutyric acid (GABA) B receptor, 1; gb1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8201,469,779 - 1,499,352 (-)NCBIGRCr8
mRatBN7.2201,464,534 - 1,494,114 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl201,464,534 - 1,493,994 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx201,517,886 - 1,547,375 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0201,521,372 - 1,550,860 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0201,462,860 - 1,492,324 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0201,955,344 - 1,984,907 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl201,955,359 - 1,984,863 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0203,996,333 - 4,025,508 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4201,553,297 - 1,582,426 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1201,554,603 - 1,577,774 (-)NCBI
Celera202,173,047 - 2,202,332 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2,2-trifluoroethanol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-dinitrotoluene  (EXP)
3,3-diphenyl-N-(1-phenylethyl)-1-propanamine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
acrylamide  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
baclofen  (ISO)
Benoxacor  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (EXP,ISO)
calcidiol  (EXP)
calcium atom  (EXP,ISO)
calcium(0)  (EXP,ISO)
chaetocin  (EXP)
chloral hydrate  (ISO)
Chloralose  (ISO)
chlorobutanol  (ISO)
choline  (EXP)
clozapine  (ISO)
cocaine  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
decabromodiphenyl ether  (EXP)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
diazepam  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dichlorine  (EXP)
diethylstilbestrol  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
enflurane  (ISO)
ethanol  (ISO)
ether  (ISO)
ethylene glycol bis(2-aminoethyl)tetraacetic acid  (ISO)
fenvalerate  (EXP)
fulvestrant  (ISO)
gabapentin  (ISO)
gamma-aminobutyric acid  (EXP,ISO)
gentamycin  (EXP)
glyphosate  (EXP)
hexachlorophene  (ISO)
isoflurane  (ISO)
ketoconazole  (EXP)
lead(0)  (ISO)
leflunomide  (ISO)
linalool  (EXP)
methimazole  (EXP)
methoxyflurane  (ISO)
oxaliplatin  (EXP)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
phencyclidine  (ISO)
phenylmercury acetate  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
SB 431542  (ISO)
scopolamine  (EXP)
sevoflurane  (ISO)
sodium arsenite  (ISO)
T-2 toxin  (EXP,ISO)
tebufenpyrad  (ISO)
tert-butanol  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thapsigargin  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
triadimefon  (EXP)
tribromoethanol  (ISO)
trichloroethene  (EXP,ISO)
trifluoperazine  (ISO)
triptonide  (ISO)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Lamina-specific differences in GABA(B) autoreceptor-mediated regulation of spontaneous GABA release in rat entorhinal cortex. Bailey SJ, etal., Neuropharmacology. 2004 Jan;46(1):31-42.
2. [Expression of gamma-amino butyric acid and its receptor in the marginal division of rat striatum] Bao XM, etal., Di Yi Jun Yi Da Xue Xue Bao 2002 Nov;22(11):961-5.
3. Cellular and subcellular localization of the GABA(B) receptor 1a/b subunit in the rat periaqueductal gray matter. Barbaresi P J Comp Neurol. 2007 Dec 10;505(5):478-92.
4. Structural analysis of the complement control protein (CCP) modules of GABA(B) receptor 1a: only one of the two CCP modules is compactly folded. Blein S, etal., J Biol Chem. 2004 Nov 12;279(46):48292-306. Epub 2004 Aug 9.
5. GABA-B receptor activation in the rat globus pallidus potently suppresses pentylenetetrazol-induced tonic seizures. Chen L, etal., J Biomed Sci. 2004 Jul-Aug;11(4):457-64.
6. Constitutive expression of functional GABA(B) receptors in mIL-tsA58 cells requires both GABA(B(1)) and GABA(B(2)) genes. Chronwall BM, etal., J Neurochem 2001 Jun;77(5):1237-47.
7. The oligomeric state sets GABA(B) receptor signalling efficacy. Comps-Agrar L, etal., EMBO J. 2011 May 6;30(12):2336-49. doi: 10.1038/emboj.2011.143.
8. Evidence for pharmacologically distinct GABAB receptors associated with cAMP production in rat brain. Cunningham MD and Enna SJ, Brain Res. 1996 May 13;720(1-2):220-4.
9. GABBR1 and SLC6A1, Two Genes Involved in Modulation of GABA Synaptic Transmission, Influence Risk for Alcoholism: Results from Three Ethnically Diverse Populations. Enoch MA, etal., Alcohol Clin Exp Res. 2016 Jan;40(1):93-101. doi: 10.1111/acer.12929.
10. GABAergic gene expression in postmortem hippocampus from alcoholics and cocaine addicts; corresponding findings in alcohol-naïve P and NP rats. Enoch MA, etal., PLoS One. 2012;7(1):e29369. doi: 10.1371/journal.pone.0029369. Epub 2012 Jan 13.
11. Baclofen antagonizes nicotine-, cocaine-, and morphine-induced dopamine release in the nucleus accumbens of rat. Fadda P, etal., Synapse. 2003 Oct;50(1):1-6.
12. Functional GABA(B) receptors expressed in cultured calvarial osteoblasts. Fujimori S, etal., Biochem Biophys Res Commun 2002 May 24;293(5):1445-52.
13. An autocrine role for pituitary GABA: activation of GABA-B receptors and regulation of growth hormone levels. Gamel-Didelon K, etal., Neuroendocrinology. 2002 Sep;76(3):170-7.
14. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
15. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
16. Evidence for a selective prefrontal cortical GABA(B) receptor-mediated inhibition of glutamate release in the ventral tegmental area: a dual probe microdialysis study in the awake rat. Harte M and O'Connor WT, Neuroscience. 2005;130(1):215-22.
17. GABA receptor proteins within lipid rafts in the AY-9944 model of atypical absence seizures. Huo JZ, etal., Epilepsia. 2009 Apr;50(4):776-88.
18. Cloning and tissue distribution of novel splice variants of the rat GABAB receptor. Isomoto S, etal., Biochem Biophys Res Commun 1998 Dec 9;253(1):10-5.
19. Astrocyte-mediated potentiation of inhibitory synaptic transmission. Kang J, etal., Nat Neurosci. 1998 Dec;1(8):683-92. doi: 10.1038/3684.
20. GISP: a novel brain-specific protein that promotes surface expression and function of GABA(B) receptors. Kantamneni S, etal., J Neurochem. 2007 Feb;100(4):1003-17. Epub 2007 Jan 4.
21. Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors. Kaupmann K, etal., Nature 1997 Mar 20;386(6622):239-46.
22. Distinct localization of GABA(B) receptors relative to synaptic sites in the rat cerebellum and ventrobasal thalamus. Kulik A, etal., Eur J Neurosci 2002 Jan;15(2):291-307.
23. Subcellular localization of metabotropic GABA(B) receptor subunits GABA(B1a/b) and GABA(B2) in the rat hippocampus. Kulik A, etal., J Neurosci. 2003 Dec 3;23(35):11026-35.
24. Association and interaction analyses of GABBR1 and GABBR2 with nicotine dependence in European- and African-American populations. Li MD, etal., PLoS One. 2009 Sep 18;4(9):e7055. doi: 10.1371/journal.pone.0007055.
25. Ethanol modulates GABA(B) receptor expression in cortex and hippocampus of the adult rat brain. Li SP, etal., Brain Res. 2005 Nov 2;1061(1):27-35. Epub 2005 Oct 24.
26. Chronic nicotine and smoking exposure decreases GABA(B1) receptor expression in the rat hippocampus. Li SP, etal., Neurosci Lett 2002 Dec 13;334(2):135-9.
27. Prenatal GABAB1 and GABAB2 receptors: cellular and subcellular organelle localization in early fetal rat cortical neurons. Li SP, etal., Synapse. 2006 Dec 15;60(8):557-66.
28. Development of tolerance upon repeated administration with the GABAB receptor positive allosteric modulator, COR659, on alcohol drinking in rodents. Lorrai I, etal., Am J Drug Alcohol Abuse. 2022 Nov 2;48(6):662-672. doi: 10.1080/00952990.2022.2116713. Epub 2022 Sep 12.
29. GABAB receptors in Schwann cells influence proliferation and myelin protein expression. Magnaghi V, etal., Eur J Neurosci. 2004 May;19(10):2641-9.
30. Decreased central GABA B receptor binding sites in diabetic rats. Martin P, etal., Neuropsychobiology. 1988;19(3):146-8.
31. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
32. Role of GABA(B) receptor in the regulation of excitatory synaptic transmission in trigeminal motoneurons. Min MY, etal., J Biomed Sci 2002 Jul-Aug;9(4):348-58.
33. Trans-activation between 7TM domains: implication in heterodimeric GABAB receptor activation. Monnier C, etal., EMBO J. 2011 Jan 5;30(1):32-42. doi: 10.1038/emboj.2010.270. Epub 2010 Nov 9.
34. Moderation of baclofen response by a GABAB receptor polymorphism: results from the BacALD randomized controlled trial. Morley KC, etal., Addiction. 2018 Dec;113(12):2205-2213. doi: 10.1111/add.14373. Epub 2018 Jul 24.
35. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
36. The metabotropic GABAB receptor directly interacts with the activating transcription factor 4. Nehring RB, etal., J Biol Chem 2000 Nov 10;275(45):35185-91.
37. Alternative splicing generates a novel isoform of the rat metabotropic GABA(B)R1 receptor. Pfaff T, etal., Eur J Neurosci 1999 Aug;11(8):2874-82.
38. GOA pipeline RGD automated data pipeline
39. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
40. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
41. Crosstalk between GABAB and mGlu1a receptors reveals new insight into GPCR signal integration. Rives ML, etal., EMBO J. 2009 Aug 5;28(15):2195-208. doi: 10.1038/emboj.2009.177. Epub 2009 Jul 9.
42. Association analysis of exonic variants of the gene encoding the GABAB receptor and alcohol dependence. Sander T, etal., Psychiatr Genet. 1999 Jun;9(2):69-73. doi: 10.1097/00041444-199906000-00004.
43. Increased GABA B receptor subtype expression in the nucleus of the solitary tract of the spontaneously hypertensive rat. Spary EJ, etal., J Mol Neurosci. 2008 Jun;35(2):211-24. Epub 2008 Mar 13.
44. GABA Receptors Genes Polymorphisms and Alcohol Dependence: No Evidence of an Association in an Italian Male Population. Terranova C, etal., Clin Psychopharmacol Neurosci. 2014 Aug;12(2):142-8. doi: 10.9758/cpn.2014.12.2.142. Epub 2014 Aug 12.
45. The sushi domains of secreted GABA(B1) isoforms selectively impair GABA(B) heteroreceptor function. Tiao JY, etal., J Biol Chem. 2008 Nov 7;283(45):31005-11. doi: 10.1074/jbc.M804464200. Epub 2008 Sep 2.
46. Modulation of noradrenaline release in the median preoptic area by GABAergic inputs from the organum vasculosum of the lamina terminalis in the rat. Ushigome A, etal., Neurochem Int. 2004 Feb;44(3):139-44.
47. Marlin-1 is expressed in testis and associates to the cytoskeleton and GABAB receptors. Vidal RL, etal., J Cell Biochem. 2008 Feb 15;103(3):886-95.
48. Cloning and characterization of a novel variant of rat GABA(B)R1 with a truncated C-terminus. Wei K, etal., Brain Res Mol Brain Res 2001 Apr 18;89(1-2):103-10.
49. Cloning and tissue distribution of a novel isoform of the rat GABA(B)R1 receptor subunit. Wei K, etal., Neuroreport 2001 Mar 26;12(4):833-7.
50. Pre- and postsynaptic inhibition mediated by GABA(B) receptors in rat ventrolateral periaqueductal gray neurons. Yang K, etal., Biochem Biophys Res Commun. 2003 Mar 7;302(2):233-7.
51. Variants in GABBR1 Gene Are Associated with Methamphetamine Dependence and Two Years' Relapse after Drug Rehabilitation. Zhao Y, etal., J Neuroimmune Pharmacol. 2018 Dec;13(4):523-531. doi: 10.1007/s11481-018-9802-9. Epub 2018 Aug 24.
Additional References at PubMed
PMID:9872316   PMID:9872744   PMID:10075644   PMID:10328880   PMID:10658574   PMID:10692480   PMID:11498050   PMID:12527730   PMID:12535164   PMID:12649368   PMID:12711093   PMID:12763580  
PMID:12815184   PMID:12832501   PMID:12861336   PMID:12917685   PMID:12948615   PMID:14503843   PMID:15013631   PMID:15019566   PMID:15173634   PMID:15176083   PMID:15482257   PMID:15946159  
PMID:15978014   PMID:16037405   PMID:16096337   PMID:16297450   PMID:16343781   PMID:16408749   PMID:16436607   PMID:16472824   PMID:16624949   PMID:16724110   PMID:16938274   PMID:17044980  
PMID:17207629   PMID:17215590   PMID:17218355   PMID:17540011   PMID:17561812   PMID:18032562   PMID:18096145   PMID:18407377   PMID:18424635   PMID:18435423   PMID:18615498   PMID:18948198  
PMID:19052921   PMID:19211975   PMID:19229613   PMID:19328818   PMID:19640481   PMID:20400944   PMID:20643921   PMID:20643948   PMID:20826795   PMID:21144999   PMID:21184807   PMID:21212011  
PMID:21290407   PMID:21618582   PMID:21664264   PMID:21980366   PMID:22120979   PMID:22169202   PMID:22363012   PMID:22692127   PMID:22727822   PMID:22761875   PMID:22871113   PMID:23192081  
PMID:23401614   PMID:23508979   PMID:23803332   PMID:23829864   PMID:24020808   PMID:24114844   PMID:24425870   PMID:24668805   PMID:25429759   PMID:25706125   PMID:25864813   PMID:26403151  
PMID:26699387   PMID:27118845   PMID:27573246   PMID:28009293   PMID:28450542   PMID:32651311   PMID:32717394   PMID:34509561   PMID:34830020  


Genomics

Comparative Map Data
Gabbr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8201,469,779 - 1,499,352 (-)NCBIGRCr8
mRatBN7.2201,464,534 - 1,494,114 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl201,464,534 - 1,493,994 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx201,517,886 - 1,547,375 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0201,521,372 - 1,550,860 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0201,462,860 - 1,492,324 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0201,955,344 - 1,984,907 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl201,955,359 - 1,984,863 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0203,996,333 - 4,025,508 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4201,553,297 - 1,582,426 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1201,554,603 - 1,577,774 (-)NCBI
Celera202,173,047 - 2,202,332 (-)NCBICelera
Cytogenetic Map20p12NCBI
GABBR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38629,602,238 - 29,633,183 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl629,555,629 - 29,633,976 (-)EnsemblGRCh38hg38GRCh38
GRCh37629,570,015 - 29,600,960 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36629,677,984 - 29,708,839 (-)NCBINCBI36Build 36hg18NCBI36
Build 34629,677,984 - 29,708,839NCBI
Celera631,176,094 - 31,207,052 (-)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef629,377,091 - 29,408,050 (-)NCBIHuRef
CHM1_1629,572,149 - 29,603,041 (-)NCBICHM1_1
T2T-CHM13v2.0629,476,949 - 29,507,887 (-)NCBIT2T-CHM13v2.0
Gabbr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391737,356,888 - 37,385,197 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1737,356,858 - 37,385,959 (+)EnsemblGRCm39 Ensembl
GRCm381737,045,966 - 37,074,305 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1737,045,966 - 37,075,067 (+)EnsemblGRCm38mm10GRCm38
MGSCv371737,182,911 - 37,211,250 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361736,654,124 - 36,682,342 (+)NCBIMGSCv36mm8
Celera1740,469,514 - 40,497,873 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1719.16NCBI
Gabbr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495558385,255 - 115,189 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495558385,255 - 115,140 (-)NCBIChiLan1.0ChiLan1.0
GABBR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2544,209,980 - 44,252,225 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1640,173,327 - 40,215,570 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0629,405,026 - 29,437,108 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1630,065,119 - 30,095,663 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl630,065,119 - 30,095,304 (-)Ensemblpanpan1.1panPan2
GABBR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13526,212,274 - 26,243,910 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3526,213,076 - 26,237,572 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3526,026,852 - 26,036,580 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03526,519,961 - 26,546,313 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3526,519,961 - 26,547,127 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13526,175,827 - 26,201,883 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03526,235,461 - 26,261,547 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03527,705,638 - 27,731,798 (-)NCBIUU_Cfam_GSD_1.0
Gabbr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494632,454,274 - 32,483,774 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367231,107,995 - 1,137,178 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367231,108,105 - 1,137,602 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GABBR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl722,540,381 - 22,578,619 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1722,547,938 - 22,577,639 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2725,210,392 - 25,239,486 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GABBR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11742,985,816 - 43,017,278 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1742,986,513 - 43,014,577 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604429,132,753 - 29,162,814 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gabbr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475425,425,055 - 25,455,656 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475425,425,208 - 25,452,600 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gabbr1
160 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:475
Count of miRNA genes:216
Interacting mature miRNAs:248
Transcripts:ENSRNOT00000040232, ENSRNOT00000051634
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126123605Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013624629Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat

Markers in Region
D20Wox20  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2201,486,171 - 1,486,366 (+)MAPPERmRatBN7.2
Rnor_6.0201,976,981 - 1,977,175NCBIRnor6.0
Rnor_5.0204,017,606 - 4,017,800UniSTSRnor5.0
RGSC_v3.4201,574,604 - 1,574,798UniSTSRGSC3.4
Celera202,194,504 - 2,194,698UniSTS
Cytogenetic Map20p12UniSTS
RH133825  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2201,490,813 - 1,491,014 (+)MAPPERmRatBN7.2
Rnor_6.0201,981,623 - 1,981,823NCBIRnor6.0
Rnor_5.0204,022,248 - 4,022,448UniSTSRnor5.0
RGSC_v3.4201,579,247 - 1,579,447UniSTSRGSC3.4
Celera202,199,153 - 2,199,353UniSTS
RH 3.4 Map201.5UniSTS
Cytogenetic Map20p12UniSTS
RH136700  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2201,492,138 - 1,492,269 (+)MAPPERmRatBN7.2
Rnor_6.0201,982,947 - 1,983,077NCBIRnor6.0
Rnor_5.0204,023,572 - 4,023,702UniSTSRnor5.0
RGSC_v3.4201,580,571 - 1,580,701UniSTSRGSC3.4
Celera202,200,477 - 2,200,607UniSTS
Cytogenetic Map20p12UniSTS
RH138703  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2201,468,689 - 1,468,845 (+)MAPPERmRatBN7.2
Rnor_6.0201,959,500 - 1,959,655NCBIRnor6.0
Rnor_5.0204,000,489 - 4,000,644UniSTSRnor5.0
RGSC_v3.4201,557,453 - 1,557,608UniSTSRGSC3.4
Celera202,177,197 - 2,177,352UniSTS
RH 3.4 Map201.8UniSTS
Cytogenetic Map20p12UniSTS
UniSTS:496042  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2201,466,624 - 1,466,728 (+)MAPPERmRatBN7.2
Rnor_6.0201,957,435 - 1,957,538NCBIRnor6.0
Rnor_5.0203,998,424 - 3,998,527UniSTSRnor5.0
RGSC_v3.4201,555,388 - 1,555,491UniSTSRGSC3.4
Celera202,175,132 - 2,175,235UniSTS
Cytogenetic Map20p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_031028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006255879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005497343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB016160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB016161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC108572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF283276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF312319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF542081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH007482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ831471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ831472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM418837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX883052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y10369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y10370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000040232   ⟹   ENSRNOP00000047788
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl201,464,558 - 1,493,439 (-)Ensembl
Rnor_6.0 Ensembl201,955,368 - 1,984,737 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000051634   ⟹   ENSRNOP00000047498
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl201,464,534 - 1,493,994 (-)Ensembl
Rnor_6.0 Ensembl201,955,359 - 1,984,774 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000078531
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl201,979,804 - 1,984,247 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000079445   ⟹   ENSRNOP00000074507
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl201,981,436 - 1,984,802 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000082545   ⟹   ENSRNOP00000075630
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl201,956,651 - 1,980,150 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000084582   ⟹   ENSRNOP00000075610
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl201,464,534 - 1,493,439 (-)Ensembl
Rnor_6.0 Ensembl201,956,577 - 1,980,101 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000085050   ⟹   ENSRNOP00000075181
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl201,464,534 - 1,493,439 (-)Ensembl
Rnor_6.0 Ensembl201,956,379 - 1,980,150 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000087524   ⟹   ENSRNOP00000070386
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl201,956,622 - 1,984,720 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000088396   ⟹   ENSRNOP00000072226
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl201,464,549 - 1,489,444 (-)Ensembl
Rnor_6.0 Ensembl201,955,359 - 1,980,253 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000089485
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl201,959,633 - 1,960,651 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000090936   ⟹   ENSRNOP00000071413
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl201,464,534 - 1,493,439 (-)Ensembl
Rnor_6.0 Ensembl201,956,622 - 1,984,720 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000090937   ⟹   ENSRNOP00000069181
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl201,956,555 - 1,984,863 (-)Ensembl
RefSeq Acc Id: NM_031028   ⟹   NP_112290
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8201,469,779 - 1,499,236 (-)NCBI
mRatBN7.2201,464,534 - 1,493,994 (-)NCBI
Rnor_6.0201,955,344 - 1,984,802 (-)NCBI
Rnor_5.0203,996,333 - 4,025,508 (-)NCBI
RGSC_v3.4201,553,297 - 1,582,426 (-)RGD
Celera202,173,047 - 2,202,332 (-)RGD
Sequence:
RefSeq Acc Id: XM_006255879   ⟹   XP_006255941
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8201,469,794 - 1,499,349 (-)NCBI
mRatBN7.2201,464,534 - 1,494,112 (-)NCBI
Rnor_6.0201,955,352 - 1,984,907 (-)NCBI
Rnor_5.0203,996,333 - 4,025,508 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039099118   ⟹   XP_038955046
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8201,469,794 - 1,499,349 (-)NCBI
mRatBN7.2201,465,110 - 1,493,923 (-)NCBI
RefSeq Acc Id: XM_063279560   ⟹   XP_063135630
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8201,469,794 - 1,499,344 (-)NCBI
RefSeq Acc Id: XR_005497343
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8201,475,079 - 1,499,352 (-)NCBI
mRatBN7.2201,469,834 - 1,494,114 (-)NCBI
Protein Sequences
Protein RefSeqs NP_112290 (Get FASTA)   NCBI Sequence Viewer  
  XP_006255941 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955046 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135630 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD19656 (Get FASTA)   NCBI Sequence Viewer  
  AAD19657 (Get FASTA)   NCBI Sequence Viewer  
  AAD19658 (Get FASTA)   NCBI Sequence Viewer  
  AAD19659 (Get FASTA)   NCBI Sequence Viewer  
  AAK69540 (Get FASTA)   NCBI Sequence Viewer  
  AAL26807 (Get FASTA)   NCBI Sequence Viewer  
  AAQ11382 (Get FASTA)   NCBI Sequence Viewer  
  BAA34708 (Get FASTA)   NCBI Sequence Viewer  
  BAA34709 (Get FASTA)   NCBI Sequence Viewer  
  CAA71398 (Get FASTA)   NCBI Sequence Viewer  
  CAA71399 (Get FASTA)   NCBI Sequence Viewer  
  CAE84069 (Get FASTA)   NCBI Sequence Viewer  
  CAH40831 (Get FASTA)   NCBI Sequence Viewer  
  CAH40832 (Get FASTA)   NCBI Sequence Viewer  
  CAL91172 (Get FASTA)   NCBI Sequence Viewer  
  EDL84628 (Get FASTA)   NCBI Sequence Viewer  
  EDL84629 (Get FASTA)   NCBI Sequence Viewer  
  EDL84630 (Get FASTA)   NCBI Sequence Viewer  
  EDL84631 (Get FASTA)   NCBI Sequence Viewer  
  EDL84632 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000047498.6
  ENSRNOP00000047788.5
  ENSRNOP00000071413
  ENSRNOP00000071413.2
  ENSRNOP00000072226.1
  ENSRNOP00000075181.2
  ENSRNOP00000075610.2
  ENSRNOP00055012209
  ENSRNOP00060004025
  ENSRNOP00065038265
GenBank Protein Q9Z0U4 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_112290   ⟸   NM_031028
- Peptide Label: precursor
- UniProtKB: Q9Z308 (UniProtKB/Swiss-Prot),   Q9Z0U4 (UniProtKB/Swiss-Prot),   Q9Z0F9 (UniProtKB/Swiss-Prot),   O08621 (UniProtKB/Swiss-Prot),   O08620 (UniProtKB/Swiss-Prot),   Q6MFX8 (UniProtKB/TrEMBL),   A0A0A0MY30 (UniProtKB/TrEMBL),   A6KR59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255941   ⟸   XM_006255879
- Peptide Label: isoform X1
- UniProtKB: A6KR60 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074507   ⟸   ENSRNOT00000079445
Ensembl Acc Id: ENSRNOP00000075610   ⟸   ENSRNOT00000084582
Ensembl Acc Id: ENSRNOP00000075630   ⟸   ENSRNOT00000082545
Ensembl Acc Id: ENSRNOP00000070386   ⟸   ENSRNOT00000087524
Ensembl Acc Id: ENSRNOP00000075181   ⟸   ENSRNOT00000085050
Ensembl Acc Id: ENSRNOP00000047498   ⟸   ENSRNOT00000051634
Ensembl Acc Id: ENSRNOP00000071413   ⟸   ENSRNOT00000090936
Ensembl Acc Id: ENSRNOP00000069181   ⟸   ENSRNOT00000090937
Ensembl Acc Id: ENSRNOP00000047788   ⟸   ENSRNOT00000040232
Ensembl Acc Id: ENSRNOP00000072226   ⟸   ENSRNOT00000088396
RefSeq Acc Id: XP_038955046   ⟸   XM_039099118
- Peptide Label: isoform X2
- UniProtKB: F7FE05 (UniProtKB/TrEMBL),   A0A9K3Y6U0 (UniProtKB/TrEMBL),   Q924M0 (UniProtKB/TrEMBL),   A6KR60 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063135630   ⟸   XM_063279560
- Peptide Label: isoform X3
Protein Domains
G-protein coupled receptors family 3 profile   Sushi

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z0U4-F1-model_v2 AlphaFold Q9Z0U4 1-991 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701271
Promoter ID:EPDNEW_R11791
Type:single initiation site
Name:Gabbr1_2
Description:gamma-aminobutyric acid type B receptor subunit 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R11792  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0201,980,263 - 1,980,323EPDNEW
RGD ID:13701279
Promoter ID:EPDNEW_R11792
Type:initiation region
Name:Gabbr1_1
Description:gamma-aminobutyric acid type B receptor subunit 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R11791  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0201,984,830 - 1,984,890EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621537 AgrOrtholog
BioCyc Gene G2FUF-4988 BioCyc
Ensembl Genes ENSRNOG00000000774 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055009006 UniProtKB/Swiss-Prot
  ENSRNOG00060003245 UniProtKB/Swiss-Prot
  ENSRNOG00065026733 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000040232.7 UniProtKB/TrEMBL
  ENSRNOT00000051634.6 UniProtKB/TrEMBL
  ENSRNOT00000084582.2 UniProtKB/TrEMBL
  ENSRNOT00000085050.2 UniProtKB/Swiss-Prot
  ENSRNOT00000088396.2 UniProtKB/Swiss-Prot
  ENSRNOT00000090936 UniProtKB/TrEMBL
  ENSRNOT00000090936.2 UniProtKB/Swiss-Prot
  ENSRNOT00055015250 UniProtKB/Swiss-Prot
  ENSRNOT00060005505 UniProtKB/Swiss-Prot
  ENSRNOT00065046663 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.2300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Complement Module, domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Compl-Cell_Adhes-Reg UniProtKB/TrEMBL
  GPCR3_GABA-B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_3_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_3_GABA_rcpt_B1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sushi/SCR/CCP_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sushi_SCR_CCP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:81657 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 81657 ENTREZGENE
PANTHER COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING UniProtKB/TrEMBL
  GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10519 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUSHI DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam 7tm_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ANF_receptor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sushi UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gabbr1 PhenoGen
PRINTS GABAB1RECPTR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GABABRECEPTR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F3_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUSHI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000774 RatGTEx
  ENSRNOG00055009006 RatGTEx
  ENSRNOG00060003245 RatGTEx
  ENSRNOG00065026733 RatGTEx
SMART CCP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53822 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57535 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A0MY30 ENTREZGENE
  A0A8L2QMJ3_RAT UniProtKB/TrEMBL
  A0A8L2RAZ8_RAT UniProtKB/TrEMBL
  A0A9K3Y6U0 ENTREZGENE, UniProtKB/TrEMBL
  A6KR59 ENTREZGENE, UniProtKB/TrEMBL
  A6KR60 ENTREZGENE, UniProtKB/TrEMBL
  A6KR61_RAT UniProtKB/TrEMBL
  B5D5S8_RAT UniProtKB/TrEMBL
  F7FE05 ENTREZGENE
  GABR1_RAT UniProtKB/Swiss-Prot
  O08620 ENTREZGENE
  O08621 ENTREZGENE
  Q5CC43_RAT UniProtKB/TrEMBL
  Q5CC44_RAT UniProtKB/TrEMBL
  Q6MFX8 ENTREZGENE, UniProtKB/TrEMBL
  Q719L2_RAT UniProtKB/TrEMBL
  Q924M0 ENTREZGENE, UniProtKB/TrEMBL
  Q9Z0F9 ENTREZGENE
  Q9Z0U4 ENTREZGENE
  Q9Z308 ENTREZGENE
UniProt Secondary A0A0A0MY30 UniProtKB/TrEMBL
  F7FE05 UniProtKB/TrEMBL
  O08620 UniProtKB/Swiss-Prot
  O08621 UniProtKB/Swiss-Prot
  Q9Z0F9 UniProtKB/Swiss-Prot
  Q9Z308 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-11 Gabbr1  gamma-aminobutyric acid type B receptor subunit 1  Gabbr1  gamma-aminobutyric acid (GABA) B receptor 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Gabbr1  gamma-aminobutyric acid (GABA) B receptor 1    gamma-aminobutyric acid (GABA) B receptor, 1  Name updated 1299863 APPROVED
2002-08-07 Gabbr1  gamma-aminobutyric acid (GABA) B receptor, 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression in cerebellar Purkinje cells, cerebral cortex, thalamus and hippocampal CA1 and CA3 regions of the brain 632816
gene_expression expressed in calvarial osteoblasts 625463
gene_mapping found within the rat major histocompatibility RT1 complex 1300431
gene_product member of the metabotropic G-protein-coupled receptor for gamma-aminobutyric acid (GABA) family 632816