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heparin pharmacodynamics pathway - Ontology Report - Rat Genome Database

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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:heparin pharmacodynamics pathway
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Accession:PW:0002329 term browser browse the term
Definition:The pathway of heparin-target interaction and of the biochemical or physiological responses to drug. Heparin is a naturally occurring anticoagulant that binds to and activates the thrombin inhibitor antithrombin III (AT). Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00274

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heparin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen type I alpha 1 chain ISO SMPDB SMP:00274 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G F10 coagulation factor X ISO SMPDB SMP:00274 NCBI chr16:83,170,973...83,190,280
Ensembl chr16:76,468,838...76,488,141 		JBrowse link
G F11 coagulation factor XI ISO SMPDB SMP:00274 NCBI chr16:46,987,988...47,009,015
Ensembl chr16:46,986,107...47,008,437 		JBrowse link
G F12 coagulation factor XII ISO SMPDB SMP:00274 NCBI chr17:9,212,819...9,220,664
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G F13a1 coagulation factor XIII A1 chain ISO SMPDB SMP:00274 NCBI chr17:28,021,197...28,197,960
Ensembl chr17:27,815,702...27,992,700 		JBrowse link
G F13b coagulation factor XIII B chain ISO SMPDB SMP:00274 NCBI chr13:53,681,639...53,707,114
Ensembl chr13:51,130,920...51,156,381 		JBrowse link
G F2 coagulation factor II, thrombin ISO SMPDB SMP:00274 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G F3 coagulation factor III, tissue factor ISO SMPDB SMP:00274 NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G F5 coagulation factor V ISO SMPDB SMP:00274 NCBI chr13:79,046,657...79,116,247
Ensembl chr13:76,513,255...76,582,317 		JBrowse link
G F7 coagulation factor VII ISO SMPDB SMP:00274 NCBI chr16:83,191,896...83,202,775
Ensembl chr16:76,489,717...76,500,610 		JBrowse link
G F8 coagulation factor VIII ISO SMPDB SMP:00274 NCBI chr18:155,237...187,186
Ensembl chr18:140,955...171,857 		JBrowse link
G F9 coagulation factor IX ISO SMPDB SMP:00274 NCBI chr  X:143,388,642...143,433,143
Ensembl chr  X:138,352,298...138,396,835 		JBrowse link
G Fga fibrinogen alpha chain ISO SMPDB SMP:00274 NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgb fibrinogen beta chain ISO SMPDB SMP:00274 NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:168,394,916...168,405,979 		JBrowse link
G Fgg fibrinogen gamma chain ISO SMPDB SMP:00274 NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Ggcx gamma-glutamyl carboxylase ISO SMPDB SMP:00274 NCBI chr 4:104,469,737...104,485,631
Ensembl chr 4:104,469,765...104,487,063 		JBrowse link
G Klkb1 kallikrein B1 ISO SMPDB SMP:00274 NCBI chr16:53,690,180...53,714,570
Ensembl chr16:46,958,707...46,982,053 		JBrowse link
G Plat plasminogen activator, tissue type ISO SMPDB SMP:00274 NCBI chr16:75,943,061...76,022,037
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Plg plasminogen ISO SMPDB SMP:00274 NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:48,325,185...48,367,786 		JBrowse link
G Serpinc1 serpin family C member 1 ISO SMPDB SMP:00274 NCBI chr13:75,790,558...75,804,826
Ensembl chr13:73,257,179...73,284,293 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 ISO SMPDB SMP:00274 NCBI chr 1:182,502,491...182,505,012
Ensembl chr 1:182,500,844...182,505,008 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    drug pathway 397
      blood and blood forming organs drug pathway 62
        antithrombotic drug pathway 62
          anticoagulant drug pathway 29
            heparin group drug pathway 21
              heparin drug pathway 21
                heparin pharmacodynamics pathway 21
paths to the root