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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased interleukin-5 secretion
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Accession:MP:0008703 term browser browse the term
Definition:reduction in the production or release of a cytokine that promotes differentiation and activation of eosinophils; it also triggers activated B-cells to differentiate into immunoglobulin-secreting cells
Synonyms:exact_synonym: decreased B-cell growth factor-II secretion;   decreased BCGF-II secretion;   decreased IL-5 secretion;   decreased IL5 secretion;   decreased T-cell-replacing factor secretion;   decreased eosinophil differentiation factor secretion;   reduced B-cell growth factor-II secretion;   reduced BCGF-II secretion;   reduced IL-5 secretion;   reduced IL5 secretion;   reduced T-cell-replacing factor secretion;   reduced eosinophil differentiation factor secretion


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decreased interleukin-5 secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhlhe41 basic helix-loop-helix family, member e41 IAGP MGI PMID:19881507 NCBI chr 6:145,803,969...145,811,146
Ensembl chr 6:145,803,969...145,811,284 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IAGP MGI PMID:9463410 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccr4 C-C motif chemokine receptor 4 IAGP MGI PMID:12154006 NCBI chr 9:114,319,384...114,334,544
Ensembl chr 9:114,319,384...114,333,984 		JBrowse link
G Ccr6 C-C motif chemokine receptor 6 IAGP MGI PMID:11514610 NCBI chr17:8,454,875...8,477,353
Ensembl chr17:8,454,875...8,475,973 		JBrowse link
G Ccrl2 C-C motif chemokine receptor-like 2 IAGP MGI PMID:20606167 NCBI chr 9:110,883,902...110,886,586
Ensembl chr 9:110,883,554...110,886,587 		JBrowse link
G Commd10 COMM domain containing 10 IAGP MGI PMID:31434684 NCBI chr18:47,091,917...47,242,435
Ensembl chr18:47,091,883...47,367,351 		JBrowse link
G Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) IAGP MGI PMID:18178860 NCBI chr15:78,210,000...78,235,201
Ensembl chr15:78,209,952...78,238,047 		JBrowse link
G Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) IAGP MGI PMID:18178860 NCBI chr15:78,166,707...78,189,921
Ensembl chr15:78,166,707...78,189,921 		JBrowse link
G Ehmt2 euchromatic histone lysine N-methyltransferase 2 IAGP MGI PMID:20421388 NCBI chr17:35,117,427...35,133,049
Ensembl chr17:35,117,445...35,133,028 		JBrowse link
G Fpr2 formyl peptide receptor 2 IAGP MGI PMID:20200280 NCBI chr17:18,108,086...18,114,214
Ensembl chr17:18,108,086...18,114,214 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:22138715 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336 		JBrowse link
G Hrh1 histamine receptor H1 IAGP MGI PMID:16680192 NCBI chr 6:114,374,897...114,459,432
Ensembl chr 6:114,374,897...114,460,257 		JBrowse link
G Icos inducible T cell co-stimulator IAGP MGI PMID:17549732 NCBI chr 1:60,999,909...61,039,481
Ensembl chr 1:61,017,086...61,039,479 		JBrowse link
G Il13 interleukin 13 IAGP MGI PMID:9768762 PMID:11070175 PMID:11591797 PMID:17182558 PMID:22138715 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529 		JBrowse link
G Il17rb interleukin 17 receptor B IAGP MGI PMID:18768888 PMID:20231694 PMID:22346732 NCBI chr14:29,718,125...29,730,853
Ensembl chr14:29,718,092...29,730,853 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 IAGP MGI PMID:10727469 PMID:10940882 NCBI chr 1:40,444,105...40,504,575
Ensembl chr 1:40,468,730...40,504,575 		JBrowse link
G Il25 interleukin 25 IAGP MGI PMID:16606668 PMID:20154671 PMID:25888259 NCBI chr14:55,170,152...55,173,294
Ensembl chr14:55,170,152...55,173,294 		JBrowse link
G Il4 interleukin 4 IAGP MGI PMID:7598937 PMID:8384701 PMID:8906833 PMID:11591797 PMID:17182558 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Il4ra interleukin 4 receptor, alpha IAGP MGI PMID:9380721 NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646 		JBrowse link
G Il5 interleukin 5 IAGP MGI PMID:22174445 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933 		JBrowse link
G Itk IL2 inducible T cell kinase IAGP MGI PMID:15345221 NCBI chr11:46,215,975...46,280,342
Ensembl chr11:46,215,977...46,280,342 		JBrowse link
G Nbr1 NBR1, autophagy cargo receptor IAGP MGI PMID:20808283 NCBI chr11:101,442,933...101,472,777
Ensembl chr11:101,442,975...101,472,777 		JBrowse link
G Nfatc2ip nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein IAGP MGI PMID:20133688 NCBI chr 7:125,982,025...125,995,909
Ensembl chr 7:125,982,026...125,995,909 		JBrowse link
G Prkcq protein kinase C, theta IAGP MGI PMID:15528385 NCBI chr 2:11,176,922...11,306,033
Ensembl chr 2:11,176,919...11,306,033 		JBrowse link
G Rad50 RAD50 double strand break repair protein IAGP MGI PMID:15608641 PMID:20483988 PMID:23569250 NCBI chr11:53,540,346...53,598,146
Ensembl chr11:53,540,346...53,598,146 		JBrowse link
G Rag1 recombination activating 1 IAGP MGI PMID:15345221 NCBI chr 2:101,468,597...101,479,877
Ensembl chr 2:101,468,627...101,479,846 		JBrowse link
G Retnla resistin like alpha IAGP MGI PMID:19201890 NCBI chr16:48,662,972...48,664,824
Ensembl chr16:48,662,914...48,664,824 		JBrowse link
G Rnf128 ring finger protein 128 IAGP MGI PMID:20493730 NCBI chr  X:138,464,089...138,573,894
Ensembl chr  X:138,464,065...138,573,894 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 IAGP MGI PMID:19047684 NCBI chr12:26,492,742...26,506,451
Ensembl chr12:26,492,745...26,506,451 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 IAGP MGI PMID:8624821 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826 		JBrowse link
G Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 IAGP MGI PMID:20808283 NCBI chr 4:156,098,049...156,101,070
Ensembl chr 4:156,098,300...156,101,069 		JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 IAGP MGI PMID:9950424 NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483 		JBrowse link
G Yeats4 YEATS domain containing 4 IAGP MGI PMID:31434684 NCBI chr10:117,051,046...117,060,412
Ensembl chr10:117,051,126...117,060,412 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  mammalian phenotype 17059
    immune system phenotype 5760
      abnormal immune system physiology 3494
        abnormal immune serum protein physiology 1478
          abnormal cytokine secretion 837
            abnormal interleukin secretion 611
              abnormal interleukin-5 secretion 59
                decreased interleukin-5 secretion 33
paths to the root