Icos (inducible T cell co-stimulator)

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Gene: Icos (inducible T cell co-stimulator) Mus musculus

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Symbol:

Icos

Name:

inducible T cell co-stimulator

RGD ID:

732863

MGI Page

MGI

Description:

Predicted to be involved in T cell costimulation; T cell tolerance induction; and cell-cell adhesion. Located in external side of plasma membrane. Used to study common variable immunodeficiency. Human ortholog(s) of this gene implicated in celiac disease; common variable immunodeficiency 1; and immunoglobulin alpha deficiency. Orthologous to human ICOS (inducible T cell costimulator).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

activation-inducible lymphocyte immunomediatory molecule; AILIM; CCLP; CD28 and CTLA-4-like protein; CD28-related protein 1; CRP-1; H4; inducible T-cell co-stimulator; inducible T-cell costimulator; Ly115

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ICOS (inducible T cell costimulator)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Icos (inducible T-cell co-stimulator)	RGD	RGD
Chinchilla lanigera (long-tailed chinchilla):	Icos (inducible T cell costimulator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ICOS (inducible T cell costimulator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ICOS (inducible T cell costimulator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Icos (inducible T cell costimulator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ICOS (inducible T cell costimulator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ICOS (inducible T cell costimulator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Icos (inducible T cell costimulator)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Icos (inducible T-cell co-stimulator)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ICOS (inducible T cell costimulator)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	60,999,909 - 61,039,481 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	61,017,086 - 61,039,479 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	60,960,773 - 61,000,322 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	60,977,927 - 61,000,320 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	61,034,758 - 61,057,164 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	60,922,469 - 60,943,665 (+)	NCBI		MGSCv36	mm8
Celera	1	61,493,037 - 61,515,464 (+)	NCBI		Celera
Cytogenetic Map	1	C2	NCBI
cM Map	1	30.6	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

adult T-cell leukemia/lymphoma (ISO)

arteriosclerosis (IMP)

autoimmune lymphoproliferative syndrome type 2B (ISO)

Autoimmune Lymphoproliferative Syndrome, Type V (ISO)

celiac disease (ISO)

colitis (ISO)

common variable immunodeficiency (IAGP,ISO)

common variable immunodeficiency 1 (ISO)

genetic disease (ISO)

Gram-Positive Bacterial Infections (IDA)

immunoglobulin alpha deficiency (ISO)

myocarditis (ISO)

Neurodevelopmental Disorders (ISO)

primary immunodeficiency disease (ISO)

primary pulmonary hypertension (ISO)

Pulmonary Arterial Hypertension (ISO)

uveitis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

17beta-estradiol (ISO)

17beta-estradiol 3-benzoate (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (EXP)

4,4'-diaminodiphenylmethane (EXP)

4-hydroxyphenyl retinamide (EXP)

acetamide (ISO)

acrolein (EXP)

aflatoxin B1 (ISO)

alpha-Zearalanol (ISO)

atrazine (ISO)

benzo[a]pyrene (EXP,ISO)

bisphenol A (EXP,ISO)

carbon nanotube (EXP)

choline (EXP)

dibutyl phthalate (EXP)

Didecyldimethylammonium (EXP)

dieldrin (ISO)

dimethylarsinic acid (EXP)

disodium selenite (ISO)

folic acid (EXP)

genistein (EXP)

gentamycin (ISO)

GW 4064 (EXP)

L-methionine (EXP)

methylarsonic acid (EXP)

nickel atom (ISO)

paracetamol (ISO)

pirinixic acid (EXP)

silicon dioxide (EXP,ISO)

sodium arsenate (EXP)

sodium arsenite (EXP)

testosterone (ISO)

titanium dioxide (EXP)

toluene 2,4-diisocyanate (EXP)

trimellitic anhydride (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell-cell adhesion (IBA,ISO)

T cell costimulation (IBA,IEA,ISO)

T cell tolerance induction (IBA,ISO)

T follicular helper cell differentiation (ISO)

Cellular Component

external side of plasma membrane (IDA)

plasma membrane (IDA,ISO)

Molecular Function

protein binding (IPI)

signaling receptor activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

primary immunodeficiency pathway (IEA)

T cell receptor signaling pathway (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal B cell number (IAGP)

abnormal B cell physiology (IAGP)

abnormal B cell selection (IAGP)

abnormal CD4-positive, alpha-beta T cell physiology (IAGP)

abnormal class switch recombination (IAGP)

abnormal cytokine level (IAGP)

abnormal cytokine secretion (IAGP)

abnormal immune system physiology (IAGP)

abnormal immunoglobulin level (IAGP)

abnormal interferon level (IAGP)

abnormal interleukin level (IAGP)

abnormal interleukin secretion (IAGP)

abnormal leukocyte cell number (IAGP)

abnormal memory B cell number (IAGP)

abnormal NK cell physiology (IAGP)

abnormal Peyer's patch germinal center morphology (IAGP)

abnormal response to infection (IAGP)

abnormal small intestine morphology (IAGP)

abnormal spleen germinal center morphology (IAGP)

abnormal spleen morphology (IAGP)

abnormal T cell differentiation (IAGP)

abnormal T cell physiology (IAGP)

abnormal T-helper 2 physiology (IAGP)

decreased anti-insulin autoantibody level (IAGP)

decreased autoantibody level (IAGP)

decreased CD4-positive, alpha-beta T cell number (IAGP)

decreased circulating interferon-gamma level (IAGP)

decreased circulating interleukin-4 level (IAGP)

decreased germinal center B cell number (IAGP)

decreased IgA level (IAGP)

decreased IgE level (IAGP)

decreased IgG level (IAGP)

decreased IgG1 level (IAGP)

decreased IgG2a level (IAGP)

decreased IgG2b level (IAGP)

decreased IgG2c level (IAGP)

decreased interferon-gamma secretion (IAGP)

decreased interleukin-21 secretion (IAGP)

decreased interleukin-4 secretion (IAGP)

decreased interleukin-5 secretion (IAGP)

decreased lymphoma incidence (IAGP)

decreased pancreatic islet number (IAGP)

decreased plasma cell number (IAGP)

decreased spleen germinal center number (IAGP)

decreased spleen germinal center size (IAGP)

decreased susceptibility to autoimmune diabetes (IAGP)

decreased T cell number (IAGP)

decreased T cell proliferation (IAGP)

increased IgG3 level (IAGP)

increased plasma cell number (IAGP)

increased susceptibility to experimental autoimmune encephalomyelitis (IAGP)

increased T cell derived lymphoma incidence (IAGP)

insulitis (IAGP)

short tibia (IEA)

small lymph nodes (IAGP)

small Peyer's patches (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Attenuation of experimental autoimmune myocarditis by blocking activated T cells through inducible costimulatory molecule pathway.	Futamatsu H, etal., Cardiovasc Res. 2003 Jul 1;59(1):95-104.
2.	Impaired regulatory T-cell response and enhanced atherosclerosis in the absence of inducible costimulatory molecule.	Gotsman I, etal., Circulation. 2006 Nov 7;114(19):2047-55. Epub 2006 Oct 23.
3.	The shared CTLA4-ICOS risk locus in celiac disease, IgA deficiency and common variable immunodeficiency.	Haimila K, etal., Genes Immun. 2009 Mar;10(2):151-61. doi: 10.1038/gene.2008.89. Epub 2008 Nov 20.
4.	Hyperexpression of inducible costimulator on lamina propria mononuclear cells in rat dextran sulfate sodium colitis.	Ishii K, etal., J Gastroenterol Hepatol. 2004 Feb;19(2):174-81.
5.	MGDs mouse GO annotations	MGD data from the GO Consortium
6.	MGD IEA	MGD IEA
7.	Inducible costimulator protein controls the protective T cell response against Listeria monocytogenes.	Mittrucker HW, etal., J Immunol. 2002 Nov 15;169(10):5813-7.
8.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
9.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
10.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
11.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
13.	Inducible co-stimulator (ICOS) is upregulated in experimental autoimmune uveoretinitis.	Xing L, etal., Graefes Arch Clin Exp Ophthalmol. 2006 Apr 7;.

Additional References at PubMed

PMID:10349636	PMID:10617205	PMID:10657606	PMID:10760791	PMID:10880526	PMID:11006126	PMID:11042159	PMID:11076861	PMID:11217851	PMID:11238604	PMID:11247636	PMID:11343121
PMID:11343122	PMID:11343123	PMID:11429542	PMID:11489981	PMID:11707574	PMID:11723074	PMID:11735222	PMID:11801630	PMID:12039907	PMID:12044964	PMID:12097399	PMID:12145647
PMID:12244160	PMID:12370365	PMID:12432568	PMID:12456021	PMID:12466851	PMID:12477932	PMID:12538658	PMID:12538664	PMID:12594252	PMID:12594849	PMID:12645936	PMID:12717187
PMID:12847246	PMID:12853164	PMID:12960306	PMID:14556978	PMID:14599850	PMID:14615582	PMID:14634147	PMID:15128772	PMID:15368302	PMID:15489334	PMID:15514586	PMID:15629449
PMID:15699103	PMID:15699127	PMID:15728513	PMID:15809349	PMID:15880041	PMID:15917267	PMID:15941568	PMID:15956289	PMID:15972646	PMID:15994233	PMID:16081804	PMID:16141072
PMID:16141073	PMID:16200068	PMID:16212904	PMID:16227984	PMID:16300749	PMID:16301634	PMID:16301640	PMID:16380473	PMID:16428752	PMID:16500623	PMID:16616645	PMID:16635747
PMID:16724117	PMID:16751384	PMID:16783640	PMID:16880206	PMID:16887998	PMID:16982935	PMID:16990558	PMID:17014982	PMID:17039566	PMID:17039567	PMID:17114448	PMID:17549732
PMID:17635872	PMID:17889619	PMID:17986443	PMID:18172933	PMID:18178815	PMID:18250436	PMID:18250437	PMID:18292537	PMID:18310064	PMID:18390703	PMID:18390727	PMID:18606653
PMID:18684917	PMID:18976292	PMID:18981236	PMID:18988696	PMID:19008373	PMID:19050242	PMID:19098919	PMID:19194830	PMID:19217324	PMID:19249753	PMID:19291374	PMID:19299705
PMID:19448155	PMID:19570826	PMID:19603141	PMID:19608860	PMID:19646680	PMID:19888475	PMID:19889730	PMID:19914290	PMID:19915142	PMID:20022728	PMID:20544729	PMID:20624644
PMID:20691615	PMID:21267068	PMID:21337542	PMID:21364749	PMID:21421907	PMID:21447398	PMID:21544030	PMID:21636296	PMID:21677750	PMID:21873635	PMID:21925472	PMID:22018468
PMID:22154192	PMID:22156342	PMID:22172879	PMID:22227569	PMID:22231701	PMID:22532671	PMID:22547698	PMID:22585681	PMID:22661090	PMID:22700722	PMID:22815292	PMID:22949644
PMID:23285133	PMID:23319295	PMID:23498793	PMID:23583643	PMID:23619696	PMID:23729441	PMID:23926322	PMID:23967339	PMID:24100657	PMID:24378539	PMID:24486724	PMID:24778280
PMID:24820310	PMID:25088770	PMID:25347065	PMID:25436971	PMID:25464855	PMID:25576595	PMID:25646266	PMID:25692700	PMID:25754933	PMID:25769613	PMID:25884798	PMID:25918344
PMID:26049110	PMID:26109645	PMID:26198302	PMID:26249010	PMID:26410627	PMID:26459508	PMID:26667167	PMID:26767258	PMID:27022145	PMID:27135603	PMID:27235509	PMID:27296665
PMID:27760760	PMID:27812214	PMID:28002569	PMID:28297661	PMID:28424681	PMID:28488693	PMID:29352114	PMID:29378030	PMID:29581356	PMID:29676593	PMID:29907525	PMID:30076099
PMID:30523347	PMID:30642977	PMID:30655308	PMID:30718297	PMID:30926234	PMID:31283790	PMID:31413107	PMID:31466995	PMID:31978191	PMID:32160524	PMID:32289155	PMID:32999002
PMID:33106594	PMID:33495237	PMID:33881452	PMID:34076685	PMID:34644536	PMID:34795444	PMID:34852236	PMID:34925367	PMID:34932944	PMID:35007126	PMID:35090581	PMID:35508704
PMID:35760518	PMID:35806368	PMID:36119089	PMID:36159872	PMID:36751013	PMID:36754569	PMID:36935092	PMID:37691688	PMID:38363829	PMID:38723638	PMID:38761804	PMID:38861924
PMID:38995175

Genomics

Comparative Map Data

Icos
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	60,999,909 - 61,039,481 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	61,017,086 - 61,039,479 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	60,960,773 - 61,000,322 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	60,977,927 - 61,000,320 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	61,034,758 - 61,057,164 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	60,922,469 - 60,943,665 (+)	NCBI		MGSCv36	mm8
Celera	1	61,493,037 - 61,515,464 (+)	NCBI		Celera
Cytogenetic Map	1	C2	NCBI
cM Map	1	30.6	NCBI

ICOS
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	203,936,763 - 203,961,577 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	203,936,763 - 203,961,577 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	204,801,486 - 204,826,300 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	204,509,748 - 204,534,545 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	204,627,008 - 204,651,802	NCBI
Celera	2	198,556,278 - 198,581,105 (+)	NCBI		Celera
Cytogenetic Map	2	q33.2	NCBI
HuRef	2	196,648,626 - 196,673,332 (+)	NCBI		HuRef
CHM1_1	2	204,807,968 - 204,832,793 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	204,418,652 - 204,443,466 (+)	NCBI		T2T-CHM13v2.0

Icos
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	69,862,042 - 69,900,864 (+)	NCBI		GRCr8
mRatBN7.2	9	62,368,075 - 62,406,900 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	62,383,832 - 62,405,672 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	70,885,818 - 70,907,670 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	76,001,432 - 76,023,292 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	74,320,006 - 74,341,864 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	67,748,157 - 67,786,808 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	67,763,897 - 67,785,580 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	67,563,758 - 67,599,683 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	9	59,806,431 - 59,827,774 (+)	NCBI		Celera
Cytogenetic Map	9	q32	NCBI

Icos
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955457	10,934,341 - 10,952,404 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955457	10,934,390 - 10,952,318 (-)	NCBI	ChiLan1.0	ChiLan1.0

ICOS
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	106,541,524 - 106,566,298 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	106,556,516 - 106,581,290 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	91,168,998 - 91,193,808 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	209,307,938 - 209,332,734 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	209,307,938 - 209,332,734 (+)	Ensembl	panpan1.1		panPan2

ICOS
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	12,663,839 - 12,735,266 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	12,670,999 - 12,733,458 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	37	13,596,013 - 13,616,605 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	37	12,600,441 - 12,671,981 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	37	12,607,586 - 12,670,174 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	37	12,606,503 - 12,627,090 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	37	12,569,911 - 12,590,566 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	37	12,571,149 - 12,591,783 (+)	NCBI		UU_Cfam_GSD_1.0

Icos
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	160,927,573 - 160,937,186 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936631	551,394 - 570,804 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936631	562,650 - 572,263 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ICOS
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	107,350,203 - 107,370,119 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	107,350,253 - 107,370,123 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	118,697,582 - 118,717,451 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ICOS
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	89,706,755 - 89,732,600 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	89,726,489 - 89,732,944 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	109,655,109 - 109,680,201 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Icos
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624765	12,352,042 - 12,372,861 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624765	12,351,695 - 12,417,847 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	904
Count of miRNA genes:	529
Interacting mature miRNAs:	634
Transcripts:	ENSMUST00000027162, ENSMUST00000102827
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
11039528	Ccc3_m	colitis susceptibility in the Collaborative Cross 3 (mouse)					1	3680142	195051546	Mouse
12910788	Pwgrq9_m	post-weaning growth rate QTL 9 (mouse)					1	40868008	67270256	Mouse
18182931	Metl1_m	metabolite locus 1, pyridoxate (mouse)					1	41275399	75275399	Mouse
12910786	Pwgrq10_m	post-weaning growth rate QTL 10 (mouse)					1	40868008	67270256	Mouse
13824984	Twq5_m	testis weight QTL 5 (mouse)					1	3069992	184732197	Mouse
1357721	Sle17_m	systematic lupus erythematosus susceptibility 17 (mouse)			Not determined		1	39132808	126445310	Mouse
1357824	Estoq4_m	embryo survival total QTL 4 (mouse)			Not determined		1	34760138	73976915	Mouse
14746998	Mancz1_m	mandible centroid size 1 (mouse)					1	57941351	91941351	Mouse
1300746	Skl1_m	skeletal size (tail length) 1 (mouse)			Not determined		1	57991977	91992080	Mouse
4141724	Idd5.1_m	insulin dependent diabetes susceptibility 5.1 (mouse)			Not determined			57728276	62946882	Mouse
1357488	Splq3_m	spleen weight QTL 3 (mouse)			Not determined		1	34760138	150193871	Mouse
10043965	Obq24_m	obesity QTL 24 (mouse)			Not determined		1	50890216	84890216	Mouse
1301430	Cdcs2_m	cytokine deficiency colitis susceptibility 2 (mouse)			Not determined		1	48892345	82892485	Mouse
1558717	Ses1a_m	salmonella enteritidis susceptibility 1a (mouse)			Not determined		1	56726922	90727077	Mouse
1357759	W3q12_m	weight 3 weeks QTL 12 (mouse)			Not determined		1	34760138	73976915	Mouse
1357753	Kidq2_m	kidney weight QTL 2 (mouse)			Not determined		1	34760138	150193871	Mouse
1301667	Lxw5_m	lupus BXSB x NZW 5 (mouse)			Not determined		1	58549191	92549443	Mouse
1558822	Vas1_m	autoimmune vasitis resistance 1 (mouse)			Not determined		1	48889006	82889210	Mouse
1301670	Ssta1_m	susceptibility to Salmonella typhimurium antigens 1 (mouse)			Not determined		1	45946755	79946882	Mouse
1357475	w3q13_m	weight 3 weeks QTL 13 (mouse)			Not determined		1	23109591	73976915	Mouse
1357741	Nidd5k_m	Nidd5 on KK-A<y> (mouse)			Not determined		1	55974948	89975057	Mouse
1301162	Skull1_m	skull morphology 1 (mouse)			Not determined		1	57991977	91992080	Mouse
4142467	Wbcq1_m	white blood cell quantitative locus 1 (mouse)			Not determined		1	56266214	90266360	Mouse
1301166	Thypr2_m	thymocyte proliferative response 2 (mouse)			Not determined		1	41273124	75273271	Mouse
1301933	Insq6_m	insulin QTL 6 (mouse)			Not determined		1	56726922	90727077	Mouse
1357524	W6q14_m	weight 6 weeks QTL 14 (mouse)			Not determined		1	34760138	73976915	Mouse
1301714	Vertcling_m	vertical clinging (mouse)			Not determined		1	42938031	76938167	Mouse
4141305	Tgq9_m	triglyceride QTL 9 (mouse)			Not determined			51421605	85421605	Mouse
1357651	Lgq5_m	late growth QTL 5 (mouse)			Not determined		1	34760138	73976915	Mouse
11100001	Col4a1m1_m	collagen, type IV, alpha 1 modifier 1 (mouse)					1	25550191	62946882	Mouse
1301211	Bbaa11_m	B.burgdorferi-associated arthritis 11 (mouse)			Not determined		1	48889006	82889210	Mouse
1301722	Cia9_m	collagen induced arthritis QTL 9 (mouse)			Not determined		1	45783900	189303617	Mouse
1558855	Eae30_m	experimental allergic encephalomyelitis susceptibility 30 (mouse)			Not determined		1	45417773	72975057	Mouse
1301954	Lrnx11_m	learning-contextual 11 (mouse)			Not determined		1	39132808	74516365	Mouse
1357505	Vtbt1_m	vertebral trabecular bone trait 1 (mouse)			Not determined		1	56266214	90266360	Mouse
1357506	W10q6_m	weight 10 weeks QTL 6 (mouse)			Not determined		1	34760138	73976915	Mouse
4141032	Wbcc1_m	white blood cell count 1 (mouse)			Not determined			42259667	76259667	Mouse
1301444	Alcw5_m	alcohol withdrawal 5 (mouse)			Not determined		1	58549191	92549443	Mouse
39128207	Lwq16_m	liver weight QTL 16 (mouse)					1	34760138	73976915	Mouse
1558860	W10q7_m	weight 10 weeks QTL 7 (mouse)			Not determined		1	34760138	150193871	Mouse
4142307	Shali1_m	survival time to hyperoxic acute lung injury 1 (mouse)			Not determined			51964025	70406589	Mouse
14747009	Manh49_m	mandible shape 49 (mouse)					1	57941351	91941351	Mouse
1301616	Yaa2_m	Y-linked autoimmune acceleration 2 (mouse)			Not determined		1	46854690	80854839	Mouse
12879917	Shm3_m	sperm head morphology 3 (mouse)					1	44186904	62946882	Mouse
4142291	Aec2_m	autoimmune exocrinopathy 2 (mouse)			Not determined			52457737	182250592	Mouse
1558905	Gct7_m	granulosa cell tumorigenesis 7 (mouse)			Not determined		1	47349894	81350013	Mouse
12910780	Pwgrq11_m	post-weaning growth rate QTL 11 (mouse)					1	40868008	67270256	Mouse
1301225	Sle7_m	systematic lupus erythematosus susceptibility 7 (mouse)			Not determined		1	46854690	80854839	Mouse
1357679	Egrm1_m	early growth rate, maternal effect 1 (mouse)			Not determined		1	57991977	91992080	Mouse

Markers in Region

AB023132

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	1	60,997,799 - 60,997,947	UniSTS	GRCm38
MGSCv37	1	61,054,643 - 61,054,791	UniSTS	GRCm37
Celera	1	61,512,943 - 61,513,091	UniSTS
Cytogenetic Map	1	C2	UniSTS
cM Map	1	32.0	UniSTS
Whitehead/MRC_RH	1	886.08	UniSTS

Icos

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	1	60,993,935 - 60,994,671	UniSTS	GRCm38
MGSCv37	1	61,050,779 - 61,051,515	UniSTS	GRCm37
Celera	1	61,509,075 - 61,509,811	UniSTS
Cytogenetic Map	1	C2	UniSTS
cM Map	1	32.0	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_017480	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006496138	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006496139	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006496140	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB023132	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF216748	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF257230	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AH010217	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AI451625	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ250559	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK030827	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL596283	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL645744	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL663047	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BB850356	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC034852	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466548	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CR936839	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GQ420691	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GQ420694	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000027162 ⟹ ENSMUSP00000027162

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	1	61,017,086 - 61,034,956 (+)	Ensembl
GRCm38.p6 Ensembl	1	60,977,927 - 60,995,797 (+)	Ensembl

Ensembl Acc Id:

ENSMUST00000102827 ⟹ ENSMUSP00000099891

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	1	61,017,086 - 61,039,479 (+)	Ensembl
GRCm38.p6 Ensembl	1	60,977,927 - 61,000,320 (+)	Ensembl

RefSeq Acc Id:

NM_017480 ⟹ NP_059508

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	1	61,017,073 - 61,039,479 (+)	NCBI
GRCm38	1	60,977,914 - 61,000,320 (+)	NCBI
MGSCv37	1	61,034,758 - 61,057,164 (+)	RGD
Celera	1	61,493,037 - 61,515,464 (+)	RGD
cM Map	1		ENTREZGENE

Sequence:

show sequence

ACTTTTGAGCACTGGAGGAGAAGACTGCAACTGCTCCTGGCAGACATGAAGCCGTACTTCTGCC
GTGTCTTTGTCTTCTGCTTCCTAATCAGACTTTTAACAGGAGAAATCAATGGCTCGGCCGATCA
TAGGATGTTTTCATTTCACAATGGAGGTGTACAGATTTCTTGTAAATACCCTGAGACTGTCCAG
CAGTTAAAAATGCGATTGTTCAGAGAGAGAGAAGTCCTCTGCGAACTCACCAAGACCAAGGGAA
GCGGAAATGCGGTGTCCATCAAGAATCCAATGCTCTGTCTATATCATCTGTCAAACAACAGCGT
CTCTTTTTTCCTAAACAACCCAGACAGCTCCCAGGGAAGCTATTACTTCTGCAGCCTGTCCATT
TTTGACCCACCTCCTTTTCAAGAAAGGAACCTTAGTGGAGGATATTTGCATATTTATGAATCCC
AGCTCTGCTGCCAGCTGAAGCTCTGGCTACCCGTAGGGTGTGCAGCTTTCGTTGTGGTACTCCT
TTTTGGATGCATACTTATCATCTGGTTTTCAAAAAAGAAATACGGATCCAGTGTGCATGACCCT
AATAGTGAATACATGTTCATGGCGGCAGTCAACACAAACAAAAAGTCTAGACTTGCAGGTGTGA
CCTCATAAGCTGGAACACCCGGACCCACAGAGGAAACGCATGGACTAGTTCCCCTGAAACTTGA
ATGGAGAAATTCTTCTATTTTCTGGACCACAGGGCACCTGACTTGATTTAACTACAGACAACAT
TCTGCTGGTGTTTTGTTTGTCTGGATCAGTGACTATCAGTCATTCAGAATTTCAGCAGACTGCC
CTGGGTTTGCTGAGTCCTTTTAAGATGAACCCCTTCTTAAGGAAGACCCAGCTCATATATATTC
AACAAACAGACCTCACTGGGATAGAATGCCCCTCTCTCCGTGCCTGATTCTAGCTATGCACTGG
CCAGGAAAACAAACATATCTCCAGCATTTTTTTACAAAAAATGCCAAGGGTATGAATCTGTAAA
GCACACAGGCAGCCAATGGCCACCATCTGTCCTCATTTTTCAGATTCCATTTTCTTTCCATGGA
GATCAGCATTCTTTCTAGAATCAGACAGTAGAGGGAGATGCTTCACAACAGAAGCGCTTGTGTT
TCTGCGATTTTGATGTATATACTTTATCGAACTCATGCATTAGAACCAACATGCTCTCTTCCAA
TTCCTAGACTCTAGCTGATCACTGCTTCAGGGCTTAGATGCCTGCTCTTGCCTTCAAATTTCCC
CTTAAAGATATGTCCACATGTCTACTTGGCAGCCTGCTGCCACTCCAAATAGGAAGCTCAGCCT
ACATTCCCTCCCACCCCTGTTGCTCAAAAAAAAAAAAAAAAATTAGTAGATATGATGTTCCCAT
ATTCTCCCTGCCAAAGTAATTTTTTCCAGAAAAGACATCTAAATTCAGTTAATATGGTTTACTA
TGTTGATATTAGTGGTAGTAAACATTTCTCAGAAACAAAAGCAAATTAATTTTGCTGTGGTGTT
TTCTACTATTATCTGTGTTTCCATGGTGCTATTAATCACAAGCTTAGCTATTTTTGTAGATCAT
ATTAAAGTTGCAAGCAAGGAAAGCAACCCTCTGTTAATGGGCAAACATTCTCCTGGGGTAGAAT
GAATTATCTATTTAGCCTGAAAGCTGCGGTTTCTGGGTGGTGGCTGCCAGACTACAGCCACACT
TTGCTCTCTCTGGGTTTGACAGGTTGAAGTAGTCCCCCTGGAGCAGCACTCCAGGCTACGCTGG
AGTCCCAGAGTTGGGAGATGCCTGGGACAAGCTGCTGCTTTGGTCTCTGGGATCTGGGAAGTAC
AGTAGGGCCAAGACAGAATTCCCTCTCCTAGAAACTATGCAGCCTGGAAGTCAGCCCTAGCACT
TTAAGATAGCCTTCTTTAGAATATGAGTTAGTTGGAAGGATTCTGAAGTGTAAAGAGCATATGA
CTGCTCTGAGCTGGACCATTTTCTCTACTTTCCTGTCTGTATGCCTAAGACTTCTGGAGCAGCC
AATGTGTATGCAACATAAAAAAACAAAAAACAAAAAAACTCACAAACTTTAAGTAAAATATGGC
TGCATCATAGTTTTAAGTTATAGTTGCTTACTTACAGTTTACTTTAAAAGTGAGCTGTGCATCA
GTATATAGTTATTACGTTAAGCATGTGTAATGCTGGCTATGTACAGTACAGTACTGAACGTGTA
ATTTGAATCAAGTATGGTGTTCTCTCTCTTCAGATGACCCGGGCAGTCTGACTGGCTTTGTTAG
GGCATTCCCCAAGTTGGACGGTCCTTTCTGTGTGAGGGTGAAGGTGCTTTACTCTGTTCCTTGA
AGGATCCCCATTCCCAACACGAACACCTAACAATGACTTCTTGAAGAACAAAATTTCTGTGAAA
TAAAATCTGGCTTAAAGAGGAGCCACTTGCTAAAAGATGTTAGCAATAATACAAAGTAAAGGCT
AAGCACTTGTGTGCAGCAATGGGCTATAACCTTGCTGTGTTTTCTGGGGGTGAAGAAGTGATGA
CCTTAGCTACCATATGCAAATTAGCCCTTGCTCTCCAATGACCTTTCGTGCTACATAAGATAGT
TGCTCCCTTTGTCTCGTTTTTCCCCTTTTAGACTCTGAAATATTCACAAGCTTATAAAAGAGTC
AGAAGCACAGGAAACAGCACGCTCTGTGCCTGAGTTAGTTTCTGCGTTGACCTCCTGGCCCCAC
AGAATGGTGCCTATTTCCTATGGAAATGAAGACTGCACTCTTGATAACTTGACAGTCACCAATA
TCAGAAAATTAACACTGATATGTCACTACCCTCTAGTCTTTGGTCTGCATTCAAGATCTTCCCC
TGGCTTCTAGGATGTATGTAGGAGCTGTAAGTTCTGCTGGGGATGTCCCTTTGTGTTCGATTGA
CCTGTCTCGGGAGTGTTCTTCAGTCTAGACAGTTCTCTTCAGCCTGTAGCCTGGGCCCTTTTGC
AGATCACACACCATTATTTTGTAGAATGTTCCTTTTGTGGGGGGTCACGCTGATGTTTCTTCAT
GAATGAAATGAGGTTACTCGTCTTTAGCAGAAATAACACAGAAGTGGTGTTGTGCCCTATAGGG
CGGCTCACATTTTGGTTTGCCAAGTAACTGCCAGTGTTTGTTTTCATCTCCTGTCAAGCTTCTC
CATTGTAAAGGGATTCTGCTCCTGAACAGCCAATAAATATGCTTTGTGAGAGAAAAAAAAAAAA
AAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006496138 ⟹ XP_006496201

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	1	60,999,909 - 61,039,481 (+)	NCBI
GRCm38	1	60,960,773 - 61,000,320 (+)	NCBI

Sequence:

show sequence

GATATCTTGGCTTCCTTCTCAAATCTCTGAGTGGACGCTCCTACACTTCCTCCTGGAGCGAAGA
GAGAAAAAAAACATGCAGCTTTGCAGGTCATCGACTCTTTCAAGGCTGACAGAGAAATTTTAAG
AAAGTAACGGAACTGCTGTGAGGATTAGACAACGAATGTTTCGCGTTTAGCACAGTACATGGAA
GAAGCGTACTGACAAACAGTGTTGTCTATAACTACGCCACACCCTTCAGGAACTTGAAACTTCC
TCTTGGGACTAAGTATACCCTTTCTCCATGAACACAAAAGGCTGATGGTGTGATGCAACTATGA
ACCCAAGTTCACTGCTTGTGAATGGAAAAAGCCAGCAACTCAAGGATAAGTTATCAGGGCAAGA
AGAGAGATTTACTTGGAAAGTTATCAAACCGAGTAAGATAGAGAGGTGGAGGTTGTTGCCAACA
TGGCTTTCTAGGACAAGATGGCCTGTAGGTTATGTAGGGATTTCTGGGGAGTCACTAGGGTAGT
TAGAAACTATGGATGCCACACTTCTGCGGGGCGTGGGTTGCTGTTATCTGTAGTCACTGAAATC
TAGATTCTGTAAATCTGAAGTTACTGATTAGAAAGACTTATGACTCATGCCCTTTCGGTCCCAT
TTCCCAGAAATAGTTAATTCTCCACTGAACTACTAACTGTATAAAAGTTACTGCGCCTCTCTGA
ATACAGAAAGAACAGCTTTTACCCTGTTGGGTGGCCTCAGTCAGAAGGGTCGTCTTCAGAAAAC
TGAAAACAACTGAGATCACGACTTCACTGACACTTTTGAGCACTGGAGGAGAAGACTGCAACTG
CTCCTGGCAGACATGAAGCCGTACTTCTGCCGTGTCTTTGTCTTCTGCTTCCTAATCAGACTTT
TAACAGGAGAAATCAATGGCTCGGCCGATCATAGGATGTTTTCATTTCACAATGGAGGTGTACA
GATTTCTTGTAAATACCCTGAGACTGTCCAGCAGTTAAAAATGCGATTGTTCAGAGAGAGAGAA
GTCCTCTGCGAACTCACCAAGACCAAGGGAAGCGGAAATGCGGTGTCCATCAAGAATCCAATGC
TCTGTCTATATCATCTGTCAAACAACAGCGTCTCTTTTTTCCTAAACAACCCAGACAGCTCCCA
GGGAAGCTATTACTTCTGCAGCCTGTCCATTTTTGACCCACCTCCTTTTCAAGAAAGGAACCTT
AGTGGAGGATATTTGCATATTTATGAATCCCAGCTCTGCTGCCAGCTGAAGCTCTGGCTACCCG
TAGGGTGTGCAGCTTTCGTTGTGGTACTCCTTTTTGGATGCATACTTATCATCTGGTTTTCAAA
AAAGAAATACGGATCCAGTGTGCATGACCCTAATAGTGAATACATGTTCATGGCGGCAGTCAAC
ACAAACAAAAAGTCTAGACTTGCAGGTGTGACCTCATAAGCTGGAACACCCGGACCCACAGAGG
AAACGCATGGACTAGTTCCCCTGAAACTTGAATGGAGAAATTCTTCTATTTTCTGGACCACAGG
GCACCTGACTTGATTTAACTACAGACAACATTCTGCTGGTGTTTTGTTTGTCTGGATCAGTGAC
TATCAGTCATTCAGAATTTCAGCAGACTGCCCTGGGTTTGCTGAGTCCTTTTAAGATGAACCCC
TTCTTAAGGAAGACCCAGCTCATATATATTCAACAAACAGACCTCACTGGGATAGAATGCCCCT
CTCTCCGTGCCTGATTCTAGCTATGCACTGGCCAGGAAAACAAACATATCTCCAGCATTTTTTT
ACAAAAAATGCCAAGGGTATGAATCTGTAAAGCACACAGGCAGCCAATGGCCACCATCTGTCCT
CATTTTTCAGATTCCATTTTCTTTCCATGGAGATCAGCATTCTTTCTAGAATCAGACAGTAGAG
GGAGATGCTTCACAACAGAAGCGCTTGTGTTTCTGCGATTTTGATGTATATACTTTATCGAACT
CATGCATTAGAACCAACATGCTCTCTTCCAATTCCTAGACTCTAGCTGATCACTGCTTCAGGGC
TTAGATGCCTGCTCTTGCCTTCAAATTTCCCCTTAAAGATATGTCCACATGTCTACTTGGCAGC
CTGCTGCCACTCCAAATAGGAAGCTCAGCCTACATTCCCTCCCACCCCTGTTGCTCAAAAAAAA
AAAAAAAAATTAGTAGATATGATGTTCCCATATTCTCCCTGCCAAAGTAATTTTTTCCAGAAAA
GACATCTAAATTCAGTTAATATGGTTTACTATGTTGATATTAGTGGTAGTAAACATTTCTCAGA
AACAAAAGCAAATTAATTTTGCTGTGGTGTTTTCTACTATTATCTGTGTTTCCATGGTGCTATT
AATCACAAGCTTAGCTATTTTTGTAGATCATATTAAAGTTGCAAGCAAGGAAAGCAACCCTCTG
TTAATGGGCAAACATTCTCCTGGGGTAGAATGAATTATCTATTTAGCCTGAAAGCTGCGGTTTC
TGGGTGGTGGCTGCCAGACTACAGCCACACTTTGCTCTCTCTGGGTTTGACAGGTTGAAGTAGT
CCCCCTGGAGCAGCACTCCAGGCTACGCTGGAGTCCCAGAGTTGGGAGATGCCTGGGACAAGCT
GCTGCTTTGGTCTCTGGGATCTGGGAAGTACAGTAGGGCCAAGACAGAATTCCCTCTCCTAGAA
ACTATGCAGCCTGGAAGTCAGCCCTAGCACTTTAAGATAGCCTTCTTTAGAATATGAGTTAGTT
GGAAGGATTCTGAAGTGTAAAGAGCATATGACTGCTCTGAGCTGGACCATTTTCTCTACTTTCC
TGTCTGTATGCCTAAGACTTCTGGAGCAGCCAATGTGTATGCAACATAAAAAAACAAAAAACAA
AAAAACTCACAAACTTTAAGTAAAATATGGCTGCATCATAGTTTTAAGTTATAGTTGCTTACTT
ACAGTTTACTTTAAAAGTGAGCTGTGCATCAGTATATAGTTATTACGTTAAGCATGTGTAATGC
TGGCTATGTACAGTACAGTACTGAACGTGTAATTTGAATCAAGTATGGTGTTCTCTCTCTTCAG
ATGACCCGGGCAGTCTGACTGGCTTTGTTAGGGCATTCCCCAAGTTGGACGGTCCTTTCTGTGT
GAGGGTGAAGGTGCTTTACTCTGTTCCTTGAAGGATCCCCATTCCCAACACGAACACCTAACAA
TGACTTCTTGAAGAACAAAATTTCTGTGAAATAAAATCTGGCTTAAAGAGGAGCCACTTGCTAA
AAGATGTTAGCAATAATACAAAGTAAAGGCTAAGCACTTGTGTGCAGCAATGGGCTATAACCTT
GCTGTGTTTTCTGGGGGTGAAGAAGTGATGACCTTAGCTACCATATGCAAATTAGCCCTTGCTC
TCCAATGACCTTTCGTGCTACATAAGATAGTTGCTCCCTTTGTCTCGTTTTTCCCCTTTTAGAC
TCTGAAATATTCACAAGCTTATAAAAGAGTCAGAAGCACAGGAAACAGCACGCTCTGTGCCTGA
GTTAGTTTCTGCGTTGACCTCCTGGCCCCACAGAATGGTGCCTATTTCCTATGGAAATGAAGAC
TGCACTCTTGATAACTTGACAGTCACCAATATCAGAAAATTAACACTGATATGTCACTACCCTC
TAGTCTTTGGTCTGCATTCAAGATCTTCCCCTGGCTTCTAGGATGTATGTAGGAGCTGTAAGTT
CTGCTGGGGATGTCCCTTTGTGTTCGATTGACCTGTCTCGGGAGTGTTCTTCAGTCTAGACAGT
TCTCTTCAGCCTGTAGCCTGGGCCCTTTTGCAGATCACACACCATTATTTTGTAGAATGTTCCT
TTTGTGGGGGGTCACGCTGATGTTTCTTCATGAATGAAATGAGGTTACTCGTCTTTAGCAGAAA
TAACACAGAAGTGGTGTTGTGCCCTATAGGGCGGCTCACATTTTGGTTTGCCAAGTAACTGCCA
GTGTTTGTTTTCATCTCCTGTCAAGCTTCTCCATTGTAAAGGGATTCTGCTCCTGAACAGCCAA
TAAATATGCTTTGTGAGAGAATA

hide sequence

RefSeq Acc Id:

XM_006496139 ⟹ XP_006496202

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	1	60,999,909 - 61,039,481 (+)	NCBI
GRCm38	1	60,960,773 - 61,000,320 (+)	NCBI

Sequence:

show sequence

GATATCTTGGCTTCCTTCTCAAATCTCTGAGTGGACGCTCCTACACTTCCTCCTGGAGCGAAGA
GAGAAAAAAAACATGCAGCTTTGCAGGTCATCGACTCTTTCAAGGCTGACAGAGAAATTTTAAG
AAAGTAACGGAACTGCTGTGAGGATTAGACAACGAATGTTTCGCGTTTAGCACAGTACATGGAA
GAAGCGTACTGACAAACAGTGTTGTCTATAACTACGCCACACCCTTCAGGAACTTGAAACTTCC
TCTTGGGACTAAGTATACCCTTTCTCCATGAACACAAAAGGCTGATGGTGTGATGCAACTATGA
ACCCAAGTTCACTGCTTGTGAATGGAAAAAGCCAGCAACTCAAGGATAAGTTATCAGGGCAAGA
AGAGAGATTTACTTGGAAAGTTATCAAACCGAAAATAGTTAATTCTCCACTGAACTACTAACTG
TATAAAAGTTACTGCGCCTCTCTGAATACAGAAAGAACAGCTTTTACCCTGTTGGGTGGCCTCA
GTCAGAAGGGTCGTCTTCAGAAAGAGGGTCACATTTTCTTCCTGCCTTCATGATCAACAAAAAT
CTGTGAATTAAGCATCCACCCTACAAACGAAAACTGAAAACAACTGAGATCACGACTTCACTGA
CACTTTTGAGCACTGGAGGAGAAGACTGCAACTGCTCCTGGCAGACATGAAGCCGTACTTCTGC
CGTGTCTTTGTCTTCTGCTTCCTAATCAGACTTTTAACAGGAGAAATCAATGGCTCGGCCGATC
ATAGGATGTTTTCATTTCACAATGGAGGTGTACAGATTTCTTGTAAATACCCTGAGACTGTCCA
GCAGTTAAAAATGCGATTGTTCAGAGAGAGAGAAGTCCTCTGCGAACTCACCAAGACCAAGGGA
AGCGGAAATGCGGTGTCCATCAAGAATCCAATGCTCTGTCTATATCATCTGTCAAACAACAGCG
TCTCTTTTTTCCTAAACAACCCAGACAGCTCCCAGGGAAGCTATTACTTCTGCAGCCTGTCCAT
TTTTGACCCACCTCCTTTTCAAGAAAGGAACCTTAGTGGAGGATATTTGCATATTTATGAATCC
CAGCTCTGCTGCCAGCTGAAGCTCTGGCTACCCGTAGGGTGTGCAGCTTTCGTTGTGGTACTCC
TTTTTGGATGCATACTTATCATCTGGTTTTCAAAAAAGAAATACGGATCCAGTGTGCATGACCC
TAATAGTGAATACATGTTCATGGCGGCAGTCAACACAAACAAAAAGTCTAGACTTGCAGGTGTG
ACCTCATAAGCTGGAACACCCGGACCCACAGAGGAAACGCATGGACTAGTTCCCCTGAAACTTG
AATGGAGAAATTCTTCTATTTTCTGGACCACAGGGCACCTGACTTGATTTAACTACAGACAACA
TTCTGCTGGTGTTTTGTTTGTCTGGATCAGTGACTATCAGTCATTCAGAATTTCAGCAGACTGC
CCTGGGTTTGCTGAGTCCTTTTAAGATGAACCCCTTCTTAAGGAAGACCCAGCTCATATATATT
CAACAAACAGACCTCACTGGGATAGAATGCCCCTCTCTCCGTGCCTGATTCTAGCTATGCACTG
GCCAGGAAAACAAACATATCTCCAGCATTTTTTTACAAAAAATGCCAAGGGTATGAATCTGTAA
AGCACACAGGCAGCCAATGGCCACCATCTGTCCTCATTTTTCAGATTCCATTTTCTTTCCATGG
AGATCAGCATTCTTTCTAGAATCAGACAGTAGAGGGAGATGCTTCACAACAGAAGCGCTTGTGT
TTCTGCGATTTTGATGTATATACTTTATCGAACTCATGCATTAGAACCAACATGCTCTCTTCCA
ATTCCTAGACTCTAGCTGATCACTGCTTCAGGGCTTAGATGCCTGCTCTTGCCTTCAAATTTCC
CCTTAAAGATATGTCCACATGTCTACTTGGCAGCCTGCTGCCACTCCAAATAGGAAGCTCAGCC
TACATTCCCTCCCACCCCTGTTGCTCAAAAAAAAAAAAAAAAATTAGTAGATATGATGTTCCCA
TATTCTCCCTGCCAAAGTAATTTTTTCCAGAAAAGACATCTAAATTCAGTTAATATGGTTTACT
ATGTTGATATTAGTGGTAGTAAACATTTCTCAGAAACAAAAGCAAATTAATTTTGCTGTGGTGT
TTTCTACTATTATCTGTGTTTCCATGGTGCTATTAATCACAAGCTTAGCTATTTTTGTAGATCA
TATTAAAGTTGCAAGCAAGGAAAGCAACCCTCTGTTAATGGGCAAACATTCTCCTGGGGTAGAA
TGAATTATCTATTTAGCCTGAAAGCTGCGGTTTCTGGGTGGTGGCTGCCAGACTACAGCCACAC
TTTGCTCTCTCTGGGTTTGACAGGTTGAAGTAGTCCCCCTGGAGCAGCACTCCAGGCTACGCTG
GAGTCCCAGAGTTGGGAGATGCCTGGGACAAGCTGCTGCTTTGGTCTCTGGGATCTGGGAAGTA
CAGTAGGGCCAAGACAGAATTCCCTCTCCTAGAAACTATGCAGCCTGGAAGTCAGCCCTAGCAC
TTTAAGATAGCCTTCTTTAGAATATGAGTTAGTTGGAAGGATTCTGAAGTGTAAAGAGCATATG
ACTGCTCTGAGCTGGACCATTTTCTCTACTTTCCTGTCTGTATGCCTAAGACTTCTGGAGCAGC
CAATGTGTATGCAACATAAAAAAACAAAAAACAAAAAAACTCACAAACTTTAAGTAAAATATGG
CTGCATCATAGTTTTAAGTTATAGTTGCTTACTTACAGTTTACTTTAAAAGTGAGCTGTGCATC
AGTATATAGTTATTACGTTAAGCATGTGTAATGCTGGCTATGTACAGTACAGTACTGAACGTGT
AATTTGAATCAAGTATGGTGTTCTCTCTCTTCAGATGACCCGGGCAGTCTGACTGGCTTTGTTA
GGGCATTCCCCAAGTTGGACGGTCCTTTCTGTGTGAGGGTGAAGGTGCTTTACTCTGTTCCTTG
AAGGATCCCCATTCCCAACACGAACACCTAACAATGACTTCTTGAAGAACAAAATTTCTGTGAA
ATAAAATCTGGCTTAAAGAGGAGCCACTTGCTAAAAGATGTTAGCAATAATACAAAGTAAAGGC
TAAGCACTTGTGTGCAGCAATGGGCTATAACCTTGCTGTGTTTTCTGGGGGTGAAGAAGTGATG
ACCTTAGCTACCATATGCAAATTAGCCCTTGCTCTCCAATGACCTTTCGTGCTACATAAGATAG
TTGCTCCCTTTGTCTCGTTTTTCCCCTTTTAGACTCTGAAATATTCACAAGCTTATAAAAGAGT
CAGAAGCACAGGAAACAGCACGCTCTGTGCCTGAGTTAGTTTCTGCGTTGACCTCCTGGCCCCA
CAGAATGGTGCCTATTTCCTATGGAAATGAAGACTGCACTCTTGATAACTTGACAGTCACCAAT
ATCAGAAAATTAACACTGATATGTCACTACCCTCTAGTCTTTGGTCTGCATTCAAGATCTTCCC
CTGGCTTCTAGGATGTATGTAGGAGCTGTAAGTTCTGCTGGGGATGTCCCTTTGTGTTCGATTG
ACCTGTCTCGGGAGTGTTCTTCAGTCTAGACAGTTCTCTTCAGCCTGTAGCCTGGGCCCTTTTG
CAGATCACACACCATTATTTTGTAGAATGTTCCTTTTGTGGGGGGTCACGCTGATGTTTCTTCA
TGAATGAAATGAGGTTACTCGTCTTTAGCAGAAATAACACAGAAGTGGTGTTGTGCCCTATAGG
GCGGCTCACATTTTGGTTTGCCAAGTAACTGCCAGTGTTTGTTTTCATCTCCTGTCAAGCTTCT
CCATTGTAAAGGGATTCTGCTCCTGAACAGCCAATAAATATGCTTTGTGAGAGAATA

hide sequence

RefSeq Acc Id:

XM_006496140 ⟹ XP_006496203

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	1	61,028,644 - 61,039,481 (+)	NCBI
GRCm38	1	60,989,485 - 61,000,322 (+)	NCBI

Sequence:

show sequence

TTCCTAGCCATCCCATATCATTCTGTAGGCAAGAAAGATAGTTGCACTCATTTTAGCATTTTCC
AGAGTCCTTGGAATATTCTTTTTTAAAAAGAAGATCGTGGGAAACATGATATCATTGAAGGGAA
CTCACCTGGCAGTGAAGATGTCTCTCTTGATTGTCTGTGATCTCTTCTAGATGCGTTAACCCAC
AGAAAGAGAAATCAATGGCTCGGCCGATCATAGGATGTTTTCATTTCACAATGGAGGTGTACAG
ATTTCTTGTAAATACCCTGAGACTGTCCAGCAGTTAAAAATGCGATTGTTCAGAGAGAGAGAAG
TCCTCTGCGAACTCACCAAGACCAAGGGAAGCGGAAATGCGGTGTCCATCAAGAATCCAATGCT
CTGTCTATATCATCTGTCAAACAACAGCGTCTCTTTTTTCCTAAACAACCCAGACAGCTCCCAG
GGAAGCTATTACTTCTGCAGCCTGTCCATTTTTGACCCACCTCCTTTTCAAGAAAGGAACCTTA
GTGGAGGATATTTGCATATTTATGAATCCCAGCTCTGCTGCCAGCTGAAGCTCTGGCTACCCGT
AGGGTGTGCAGCTTTCGTTGTGGTACTCCTTTTTGGATGCATACTTATCATCTGGTTTTCAAAA
AAGAAATACGGATCCAGTGTGCATGACCCTAATAGTGAATACATGTTCATGGCGGCAGTCAACA
CAAACAAAAAGTCTAGACTTGCAGGTGTGACCTCATAAGCTGGAACACCCGGACCCACAGAGGA
AACGCATGGACTAGTTCCCCTGAAACTTGAATGGAGAAATTCTTCTATTTTCTGGACCACAGGG
CACCTGACTTGATTTAACTACAGACAACATTCTGCTGGTGTTTTGTTTGTCTGGATCAGTGACT
ATCAGTCATTCAGAATTTCAGCAGACTGCCCTGGGTTTGCTGAGTCCTTTTAAGATGAACCCCT
TCTTAAGGAAGACCCAGCTCATATATATTCAACAAACAGACCTCACTGGGATAGAATGCCCCTC
TCTCCGTGCCTGATTCTAGCTATGCACTGGCCAGGAAAACAAACATATCTCCAGCATTTTTTTA
CAAAAAATGCCAAGGGTATGAATCTGTAAAGCACACAGGCAGCCAATGGCCACCATCTGTCCTC
ATTTTTCAGATTCCATTTTCTTTCCATGGAGATCAGCATTCTTTCTAGAATCAGACAGTAGAGG
GAGATGCTTCACAACAGAAGCGCTTGTGTTTCTGCGATTTTGATGTATATACTTTATCGAACTC
ATGCATTAGAACCAACATGCTCTCTTCCAATTCCTAGACTCTAGCTGATCACTGCTTCAGGGCT
TAGATGCCTGCTCTTGCCTTCAAATTTCCCCTTAAAGATATGTCCACATGTCTACTTGGCAGCC
TGCTGCCACTCCAAATAGGAAGCTCAGCCTACATTCCCTCCCACCCCTGTTGCTCAAAAAAAAA
AAAAAAAATTAGTAGATATGATGTTCCCATATTCTCCCTGCCAAAGTAATTTTTTCCAGAAAAG
ACATCTAAATTCAGTTAATATGGTTTACTATGTTGATATTAGTGGTAGTAAACATTTCTCAGAA
ACAAAAGCAAATTAATTTTGCTGTGGTGTTTTCTACTATTATCTGTGTTTCCATGGTGCTATTA
ATCACAAGCTTAGCTATTTTTGTAGATCATATTAAAGTTGCAAGCAAGGAAAGCAACCCTCTGT
TAATGGGCAAACATTCTCCTGGGGTAGAATGAATTATCTATTTAGCCTGAAAGCTGCGGTTTCT
GGGTGGTGGCTGCCAGACTACAGCCACACTTTGCTCTCTCTGGGTTTGACAGGTTGAAGTAGTC
CCCCTGGAGCAGCACTCCAGGCTACGCTGGAGTCCCAGAGTTGGGAGATGCCTGGGACAAGCTG
CTGCTTTGGTCTCTGGGATCTGGGAAGTACAGTAGGGCCAAGACAGAATTCCCTCTCCTAGAAA
CTATGCAGCCTGGAAGTCAGCCCTAGCACTTTAAGATAGCCTTCTTTAGAATATGAGTTAGTTG
GAAGGATTCTGAAGTGTAAAGAGCATATGACTGCTCTGAGCTGGACCATTTTCTCTACTTTCCT
GTCTGTATGCCTAAGACTTCTGGAGCAGCCAATGTGTATGCAACATAAAAAAACAAAAAACAAA
AAAACTCACAAACTTTAAGTAAAATATGGCTGCATCATAGTTTTAAGTTATAGTTGCTTACTTA
CAGTTTACTTTAAAAGTGAGCTGTGCATCAGTATATAGTTATTACGTTAAGCATGTGTAATGCT
GGCTATGTACAGTACAGTACTGAACGTGTAATTTGAATCAAGTATGGTGTTCTCTCTCTTCAGA
TGACCCGGGCAGTCTGACTGGCTTTGTTAGGGCATTCCCCAAGTTGGACGGTCCTTTCTGTGTG
AGGGTGAAGGTGCTTTACTCTGTTCCTTGAAGGATCCCCATTCCCAACACGAACACCTAACAAT
GACTTCTTGAAGAACAAAATTTCTGTGAAATAAAATCTGGCTTAAAGAGGAGCCACTTGCTAAA
AGATGTTAGCAATAATACAAAGTAAAGGCTAAGCACTTGTGTGCAGCAATGGGCTATAACCTTG
CTGTGTTTTCTGGGGGTGAAGAAGTGATGACCTTAGCTACCATATGCAAATTAGCCCTTGCTCT
CCAATGACCTTTCGTGCTACATAAGATAGTTGCTCCCTTTGTCTCGTTTTTCCCCTTTTAGACT
CTGAAATATTCACAAGCTTATAAAAGAGTCAGAAGCACAGGAAACAGCACGCTCTGTGCCTGAG
TTAGTTTCTGCGTTGACCTCCTGGCCCCACAGAATGGTGCCTATTTCCTATGGAAATGAAGACT
GCACTCTTGATAACTTGACAGTCACCAATATCAGAAAATTAACACTGATATGTCACTACCCTCT
AGTCTTTGGTCTGCATTCAAGATCTTCCCCTGGCTTCTAGGATGTATGTAGGAGCTGTAAGTTC
TGCTGGGGATGTCCCTTTGTGTTCGATTGACCTGTCTCGGGAGTGTTCTTCAGTCTAGACAGTT
CTCTTCAGCCTGTAGCCTGGGCCCTTTTGCAGATCACACACCATTATTTTGTAGAATGTTCCTT
TTGTGGGGGGTCACGCTGATGTTTCTTCATGAATGAAATGAGGTTACTCGTCTTTAGCAGAAAT
AACACAGAAGTGGTGTTGTGCCCTATAGGGCGGCTCACATTTTGGTTTGCCAAGTAACTGCCAG
TGTTTGTTTTCATCTCCTGTCAAGCTTCTCCATTGTAAAGGGATTCTGCTCCTGAACAGCCAAT
AAATATGCTTTGTGAGAGAATA

hide sequence

Protein Sequences


Protein RefSeqs	NP_059508	(Get FASTA)	NCBI Sequence Viewer
	XP_006496201	(Get FASTA)	NCBI Sequence Viewer
	XP_006496202	(Get FASTA)	NCBI Sequence Viewer
	XP_006496203	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF45150	(Get FASTA)	NCBI Sequence Viewer
	AAF70099	(Get FASTA)	NCBI Sequence Viewer
	AAG48732	(Get FASTA)	NCBI Sequence Viewer
	AAH34852	(Get FASTA)	NCBI Sequence Viewer
	ACX50463	(Get FASTA)	NCBI Sequence Viewer
	ACX50464	(Get FASTA)	NCBI Sequence Viewer
	BAA82126	(Get FASTA)	NCBI Sequence Viewer
	BAE20458	(Get FASTA)	NCBI Sequence Viewer
	CAB71153	(Get FASTA)	NCBI Sequence Viewer
	CAM13241	(Get FASTA)	NCBI Sequence Viewer
	EDL00161	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000027162.6
	ENSMUSP00000099891
	ENSMUSP00000099891.4
GenBank Protein	Q9WVS0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_059508 ⟸ NM_017480
- Peptide Label:	precursor
- UniProtKB:	Q9JL17 (UniProtKB/Swiss-Prot), Q9WVS0 (UniProtKB/Swiss-Prot), Q3V3X2 (UniProtKB/TrEMBL), Q5SUZ7 (UniProtKB/TrEMBL), A2A6A7 (UniProtKB/TrEMBL), D0E8G6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKPYFCRVFVFCFLIRLLTGEINGSADHRMFSFHNGGVQISCKYPETVQQLKMRLFREREVLCE LTKTKGSGNAVSIKNPMLCLYHLSNNSVSFFLNNPDSSQGSYYFCSLSIFDPPPFQERNLSGGY LHIYESQLCCQLKLWLPVGCAAFVVVLLFGCILIIWFSKKKYGSSVHDPNSEYMFMAAVNTNKK SRLAGVTS hide sequence

RefSeq Acc Id:	XP_006496201 ⟸ XM_006496138
- Peptide Label:	isoform X1
- UniProtKB:	Q9JL17 (UniProtKB/Swiss-Prot), Q9WVS0 (UniProtKB/Swiss-Prot), Q5SUZ7 (UniProtKB/TrEMBL), A2A6A7 (UniProtKB/TrEMBL), D0E8G6 (UniProtKB/TrEMBL), Q3V3X2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKPYFCRVFVFCFLIRLLTGEINGSADHRMFSFHNGGVQISCKYPETVQQLKMRLFREREVLCE LTKTKGSGNAVSIKNPMLCLYHLSNNSVSFFLNNPDSSQGSYYFCSLSIFDPPPFQERNLSGGY LHIYESQLCCQLKLWLPVGCAAFVVVLLFGCILIIWFSKKKYGSSVHDPNSEYMFMAAVNTNKK SRLAGVTS hide sequence

RefSeq Acc Id:	XP_006496202 ⟸ XM_006496139
- Peptide Label:	isoform X1
- UniProtKB:	Q9JL17 (UniProtKB/Swiss-Prot), Q9WVS0 (UniProtKB/Swiss-Prot), Q5SUZ7 (UniProtKB/TrEMBL), A2A6A7 (UniProtKB/TrEMBL), D0E8G6 (UniProtKB/TrEMBL), Q3V3X2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKPYFCRVFVFCFLIRLLTGEINGSADHRMFSFHNGGVQISCKYPETVQQLKMRLFREREVLCE LTKTKGSGNAVSIKNPMLCLYHLSNNSVSFFLNNPDSSQGSYYFCSLSIFDPPPFQERNLSGGY LHIYESQLCCQLKLWLPVGCAAFVVVLLFGCILIIWFSKKKYGSSVHDPNSEYMFMAAVNTNKK SRLAGVTS hide sequence

RefSeq Acc Id:	XP_006496203 ⟸ XM_006496140
- Peptide Label:	isoform X2
- UniProtKB:	A2A6A7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MFSFHNGGVQISCKYPETVQQLKMRLFREREVLCELTKTKGSGNAVSIKNPMLCLYHLSNNSVS FFLNNPDSSQGSYYFCSLSIFDPPPFQERNLSGGYLHIYESQLCCQLKLWLPVGCAAFVVVLLF GCILIIWFSKKKYGSSVHDPNSEYMFMAAVNTNKKSRLAGVTS hide sequence

Ensembl Acc Id:

ENSMUSP00000027162 ⟸ ENSMUST00000027162

Ensembl Acc Id:

ENSMUSP00000099891 ⟸ ENSMUST00000102827

Protein Domains

Ig-like V-type Immunoglobulin V-set

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9WVS0-F1-model_v2	AlphaFold	Q9WVS0	1-200	view protein structure

Promoters

RGD ID:

6873890

Promoter ID:

EPDNEW_M396

Type:

initiation region

Name:

Icos_1

Description:

Mus musculus inducible T cell co-stimulator , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	1	60,977,914 - 60,977,974	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1858745	AgrOrtholog
Ensembl Genes	ENSMUSG00000026009	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000027162.12	UniProtKB/TrEMBL
	ENSMUST00000102827	ENTREZGENE
	ENSMUST00000102827.4	UniProtKB/Swiss-Prot
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	ICOS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_V-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:54167	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD	MGI:1858745	ENTREZGENE
NCBI Gene	54167	ENTREZGENE
PANTHER	INDUCIBLE T-CELL COSTIMULATOR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR20904	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	V-set_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Icos	PhenoGen
UniProt	A2A6A6_MOUSE	UniProtKB/TrEMBL
	A2A6A7	ENTREZGENE, UniProtKB/TrEMBL
	D0E8G6	ENTREZGENE, UniProtKB/TrEMBL
	ICOS_MOUSE	UniProtKB/Swiss-Prot
	Q3V3X2	ENTREZGENE, UniProtKB/TrEMBL
	Q5SUZ7	ENTREZGENE, UniProtKB/TrEMBL
	Q5SUZ8_MOUSE	UniProtKB/TrEMBL
	Q9JL17	ENTREZGENE
	Q9WVS0	ENTREZGENE
UniProt Secondary	Q9JL17	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-02-07	Icos	inducible T cell co-stimulator	Icos	inducible T-cell co-stimulator	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

Mammalian Phenotype

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

Mammalian Phenotype