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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal uterine NK cell morphology
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Accession:MP:0008054 term browser browse the term
Definition:any structural anomaly of a natural killer cell subset that is found in the decidual of the uterus, is CD56-high, Galectin-1-positive and CD16-negative, and is the most abundant immune cell type in the decidual during the first trimester of pregnancy
Comment:Granulated metrial gland cells are found in rodents and other species, but not in primates. The human equivalent of these cells has been described as uterine NK-cells, endometrial granulocytes or K cells.
Synonyms:exact_synonym: abnormal GMG cell morphology;   abnormal dNK cell morphology;   abnormal decidual NK cell morphology;   abnormal decidual natural killer cell morphology;   abnormal granulated metrial gland cell morphology;   abnormal uNK cell morphology;   abnormal uterine natural killer cell morphology
 xref: CL:0002343


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abnormal uterine NK cell morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbn1 fibrillin 1 IAGP MGI PMID:1617705 NCBI chr 2:125,142,514...125,348,417
Ensembl chr 2:125,142,514...125,349,913 		JBrowse link
G Gab3 growth factor receptor bound protein 2-associated protein 3 IAGP MGI PMID:31375526 NCBI chr  X:74,032,151...74,128,511
Ensembl chr  X:74,010,449...74,129,064 		JBrowse link
G Ifng interferon gamma IAGP MGI PMID:10411532 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Ifngr1 interferon gamma receptor 1 IAGP MGI PMID:10411532 NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977 		JBrowse link
G Il11ra1 interleukin 11 receptor subunit alpha 1 IAGP MGI PMID:15499555 NCBI chr 4:41,760,443...41,769,473
Ensembl chr 4:41,699,989...41,769,474 		JBrowse link
G Itgb7 integrin beta 7 IAGP MGI PMID:9421796 NCBI chr15:102,124,429...102,141,840
Ensembl chr15:102,124,430...102,140,379 		JBrowse link
G Mug1 murinoglobulin 1 IAGP MGI PMID:14580373 NCBI chr 6:121,815,455...121,866,016
Ensembl chr 6:121,815,500...121,866,016 		JBrowse link
G Pzp PZP, alpha-2-macroglobulin like IAGP MGI PMID:14580373 NCBI chr 6:128,460,530...128,503,683
Ensembl chr 6:128,460,530...128,503,683 		JBrowse link
absent uterine NK cells term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbs cystathionine beta-synthase IAGP MGI PMID:22617046 NCBI chr17:31,831,602...31,856,170
Ensembl chr17:31,827,868...31,856,212 		JBrowse link
G Il15 interleukin 15 IAGP MGI PMID:12816981 NCBI chr 8:83,058,253...83,129,883
Ensembl chr 8:83,058,261...83,129,851 		JBrowse link
G Il2rb interleukin 2 receptor, beta chain IAGP MGI PMID:9002646 NCBI chr15:78,363,456...78,396,569
Ensembl chr15:78,363,456...78,379,471 		JBrowse link
G Il2rg interleukin 2 receptor, gamma chain IAGP MGI PMID:12069389 NCBI chr  X:100,307,991...100,311,861
Ensembl chr  X:100,307,984...100,311,861 		JBrowse link
decreased uterine NK cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin IAGP MGI PMID:23635772 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027 		JBrowse link
G Amhr2 anti-Mullerian hormone type 2 receptor IAGP MGI PMID:20858757 NCBI chr15:102,353,437...102,363,075
Ensembl chr15:102,353,802...102,363,068 		JBrowse link
G Calcrl calcitonin receptor-like IAGP MGI PMID:23635772 NCBI chr 2:84,160,970...84,255,786
Ensembl chr 2:84,160,970...84,255,755 		JBrowse link
G Cbs cystathionine beta-synthase IAGP MGI PMID:22617046 NCBI chr17:31,831,602...31,856,170
Ensembl chr17:31,827,868...31,856,212 		JBrowse link
G Cd247 CD247 antigen IAGP MGI PMID:15878887 NCBI chr 1:165,607,514...165,698,722
Ensembl chr 1:165,616,250...165,704,846 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit IAGP MGI PMID:30954472 NCBI chr 6:47,507,208...47,613,843
Ensembl chr 6:47,507,073...47,572,275 		JBrowse link
G Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide IAGP MGI PMID:15878887 NCBI chr 1:171,057,141...171,061,918
Ensembl chr 1:171,057,141...171,061,934 		JBrowse link
G Hcst hematopoietic cell signal transducer IAGP MGI PMID:15878887 NCBI chr 7:30,117,137...30,119,279
Ensembl chr 7:30,117,137...30,119,279 		JBrowse link
G Men1 multiple endocrine neoplasia 1 IAGP MGI PMID:35194044 NCBI chr19:6,385,009...6,390,924
Ensembl chr19:6,385,009...6,390,921 		JBrowse link
G Pgr progesterone receptor IAGP MGI PMID:28005395 PMID:30954472 PMID:35194044 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612 		JBrowse link
G Pgrmc2 progesterone receptor membrane component 2 IAGP MGI PMID:28005395 NCBI chr 3:41,020,772...41,037,443
Ensembl chr 3:41,020,761...41,037,481 		JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:20858757 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Tyrobp TYRO protein tyrosine kinase binding protein IAGP MGI PMID:15878887 NCBI chr 7:30,113,207...30,117,007
Ensembl chr 7:30,113,185...30,117,010 		JBrowse link
increased uterine NK cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin IAGP MGI PMID:23635772 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027 		JBrowse link
G Comt catechol-O-methyltransferase IAGP MGI PMID:18469803 NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602 		JBrowse link
G Emp2 epithelial membrane protein 2 IAGP MGI PMID:28295343 NCBI chr16:10,099,613...10,131,832
Ensembl chr16:10,099,613...10,131,832 		JBrowse link
G Ifng interferon gamma IAGP MGI PMID:10411532 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Ifngr1 interferon gamma receptor 1 IAGP MGI PMID:10411532 NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977 		JBrowse link
G Itgb7 integrin beta 7 IAGP MGI PMID:9421796 NCBI chr15:102,124,429...102,141,840
Ensembl chr15:102,124,430...102,140,379 		JBrowse link
G Lif leukemia inhibitory factor IAGP MGI PMID:15576827 NCBI chr11:4,207,587...4,222,514
Ensembl chr11:4,207,557...4,222,514 		JBrowse link
G Prl7d1 prolactin family 7, subfamily d, member 1 IAGP MGI PMID:31012985 NCBI chr13:27,892,981...27,900,720
Ensembl chr13:27,890,320...27,900,719 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16965
    endocrine/exocrine gland phenotype 3450
      abnormal gland morphology 3209
        abnormal sex gland morphology 1656
          abnormal female reproductive gland morphology 537
            abnormal placenta metrial gland morphology 28
              abnormal uterine NK cell morphology 28
                decreased uterine NK cell number + 16
                increased uterine NK cell number 8
Path 2
Term Annotations click to browse term
  mammalian phenotype 16965
    reproductive system phenotype 3442
      abnormal reproductive system morphology 2501
        abnormal female reproductive system morphology 900
          abnormal female genitalia morphology 897
            abnormal internal female genitalia morphology 888
              abnormal uterus morphology 508
                abnormal maternal decidual layer morphology 41
                  abnormal placenta metrial gland morphology 28
                    abnormal uterine NK cell morphology 28
                      decreased uterine NK cell number + 16
                      increased uterine NK cell number 8
paths to the root