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ONTOLOGY REPORT - ANNOTATIONS


Term:excitatory synapse assembly
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Accession:GO:1904861 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a set of components to form an excitatory synapse.
Synonyms:exact_synonym: excitatory synapse formation



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excitatory synapse assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLSTN3 calsyntenin 3 involved_in ISO (MGI:5516394|PMID:24094106) UniProt PMID:24094106 MGI:5516394 NCBI chr27:37,879,047...37,913,317
Ensembl chr27:37,879,269...37,913,281
JBrowse link
G CNTNAP2 contactin associated protein 2 involved_in ISO (PMID:31141683)
(PMID:23074245)
MGI PMID:23074245 PMID:31141683 NCBI chr16:2,239,953...4,208,718
Ensembl chr16:2,243,918...4,208,416
JBrowse link
G GRID2 glutamate ionotropic receptor delta type subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:15,322,256...16,787,966
Ensembl chr32:15,322,738...16,753,656
JBrowse link
G LRRC4 leucine rich repeat containing 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16980967) Ensembl
MGI
TreeGrafter
PMID:16980967 GO_REF:0000107 GO_REF:0000118 NCBI chr14:8,324,244...8,327,259
Ensembl chr14:8,324,788...8,326,740
JBrowse link
G NLGN1 neuroligin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:37,397,772...38,203,634
Ensembl chr34:37,572,629...38,203,177
JBrowse link
G NPTN neuroplastin involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24554721) Ensembl
MGI
PMID:24554721 GO_REF:0000107 NCBI chr30:36,846,475...36,880,096
Ensembl chr30:36,847,022...36,880,097
JBrowse link
G PLXNB2 plexin B2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:16,949,230...16,975,109
Ensembl chr10:16,963,396...16,974,705
JBrowse link
G SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:2,506,617...2,741,866 JBrowse link
gephyrin clustering involved in postsynaptic density assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLGN2 neuroligin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:29107521) Ensembl
MGI
PMID:29107521 GO_REF:0000107 NCBI chr 5:32,338,602...32,351,546
Ensembl chr 5:32,340,335...32,352,412
JBrowse link
G NRXN1 neurexin 1 involved_in ISO (MGI:5284797|PMID:15620359), (MGI:5285129|PMID:21424692) BHF-UCL PMID:15620359 PMID:21424692 MGI:5284797 MGI:5285129 NCBI chr10:51,555,660...52,666,774
Ensembl chr10:51,558,452...52,667,569
JBrowse link
G NRXN2 neurexin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:52,439,836...52,537,577
Ensembl chr18:52,439,230...52,536,401
JBrowse link
G SLITRK3 SLIT and NTRK like family member 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:29107521) Ensembl
MGI
PMID:29107521 GO_REF:0000107 NCBI chr34:30,447,606...30,456,444
Ensembl chr34:30,447,659...30,450,598
JBrowse link
G ZDHHC12 zinc finger DHHC-type palmitoyltransferase 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:54,877,188...54,880,579
Ensembl chr 9:54,877,110...54,880,553
JBrowse link
negative regulation of excitatory synapse assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLSTN3 calsyntenin 3 involved_in ISO (MGI:7275955|PMID:35420982) UniProt PMID:35420982 MGI:7275955 NCBI chr27:37,879,047...37,913,317
Ensembl chr27:37,879,269...37,913,281
JBrowse link
G PTPN13 protein tyrosine phosphatase non-receptor type 13 ISO RGD PMID:23769722 RGD:152975632 NCBI chr32:10,125,447...10,328,764
Ensembl chr32:10,125,441...10,328,757
JBrowse link
positive regulation of excitatory synapse assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SEMA4A semaphorin 4A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:41,670,814...41,695,349
Ensembl chr 7:41,672,120...41,692,460
JBrowse link
G VSTM5 V-set and transmembrane domain containing 5 involved_in ISO (MGI:5800585|PMID:27683913) UniProt PMID:27683913 MGI:5800585 NCBI chr21:6,928,557...6,960,603
Ensembl chr21:6,928,126...6,960,202
JBrowse link
G WNT7A Wnt family member 7A involved_in ISO (PMID:21670302) ParkinsonsUK-UCL PMID:21670302 NCBI chr20:4,072,010...4,139,521
Ensembl chr20:4,073,929...4,139,436
JBrowse link
postsynaptic density assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QL2 complement C1q like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:30,863,165...30,865,292
Ensembl chr19:30,863,214...30,865,716
JBrowse link
G C1QL3 complement C1q like 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:20,300,916...20,308,393
Ensembl chr 2:20,301,008...20,307,603
JBrowse link
G CSMD2 CUB and Sushi multiple domains 2 involved_in ISO (PMID:31068362) SynGO PMID:31068362 NCBI chr15:7,753,901...8,191,506 JBrowse link
G NPTX1 neuronal pentraxin 1 involved_in ISO PMID:29024665 SynGO PMID:29024665 RGD:13702141 NCBI chr 9:1,388,728...1,398,115
Ensembl chr 9:1,388,407...1,399,390
JBrowse link
G NRXN3 neurexin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:50,848,045...51,609,368
Ensembl chr 8:50,850,582...52,383,717
JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 involved_in ISO PMID:21262467 SynGO PMID:21262467 RGD:13702219 NCBI chr 3:51,131,470...51,491,112
Ensembl chr 3:51,138,751...51,513,024
JBrowse link
G PTEN phosphatase and tensin homolog involved_in ISO (MGI:3772418|PMID:18082964) CACAO PMID:18082964 MGI:3772418 NCBI chr26:37,853,148...37,913,176
Ensembl chr26:37,835,661...37,913,176
JBrowse link
G SHANK3 SH3 and multiple ankyrin repeat domains 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:16,621,445...16,665,366 JBrowse link
G SLITRK3 SLIT and NTRK like family member 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:29107521) Ensembl
MGI
PMID:29107521 GO_REF:0000107 NCBI chr34:30,447,606...30,456,444
Ensembl chr34:30,447,659...30,450,598
JBrowse link
regulation of excitatory synapse assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLSTN3 calsyntenin 3 involved_in ISO (MGI:6445033|PMID:32434929) UniProt PMID:32434929 MGI:6445033 NCBI chr27:37,879,047...37,913,317
Ensembl chr27:37,879,269...37,913,281
JBrowse link
regulation of postsynaptic density assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI3BP ABI family member 3 binding protein involved_in ISO PMID:22485184 ARUK-UCL PMID:22485184 RGD:42721990 NCBI chr33:7,265,804...7,498,973
Ensembl chr33:7,266,685...7,418,106
JBrowse link
G CASKIN1 CASK interacting protein 1 involved_in ISO (PMID:31727973) SynGO PMID:31727973 NCBI chr 6:38,776,710...38,788,253
Ensembl chr 6:38,776,710...38,786,727
JBrowse link
G CBLN1 cerebellin 1 precursor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:65,974,989...65,978,464
Ensembl chr 2:65,974,981...65,977,179
JBrowse link
G CRIPT CXXC repeat containing interactor of PDZ3 domain involved_in ISO PMID:10570482 SynGO PMID:10570482 RGD:8554363 NCBI chr10:48,840,243...48,851,461
Ensembl chr10:48,839,509...48,851,258
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 involved_in ISO (PMID:32324534) SynGO PMID:32324534 NCBI chr16:27,029,902...27,080,514
Ensembl chr16:27,031,588...27,078,261
JBrowse link
G GRID2 glutamate ionotropic receptor delta type subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:15,322,256...16,787,966
Ensembl chr32:15,322,738...16,753,656
JBrowse link
G IL1RAP interleukin 1 receptor accessory protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:22,547,422...22,628,628
Ensembl chr34:22,546,899...22,623,544
JBrowse link
G LRFN1 leucine rich repeat and fibronectin type III domain containing 1 involved_in ISO PMID:16630835 SynGO PMID:16630835 RGD:13702351 NCBI chr 1:113,888,736...113,898,240
Ensembl chr 1:113,891,484...113,898,140
JBrowse link
G LRFN4 leucine rich repeat and fibronectin type III domain containing 4 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr18:50,495,971...50,499,062
Ensembl chr18:50,495,971...50,499,068
JBrowse link
G LRRC4B leucine rich repeat containing 4B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:106,166,536...106,229,083
Ensembl chr 1:106,190,248...106,229,089
JBrowse link
G LRRTM1 leucine rich repeat transmembrane neuronal 1 involved_in ISO PMID:19285470 SynGO PMID:19285470 RGD:8554788 NCBI chr17:43,833,906...43,842,911
Ensembl chr17:43,834,562...43,836,130
JBrowse link
G LRRTM2 leucine rich repeat transmembrane neuronal 2 involved_in ISO PMID:19285470 SynGO PMID:19285470 RGD:8554788 NCBI chr11:26,392,642...26,397,018
Ensembl chr11:26,392,734...26,396,223
JBrowse link
G NLGN1 neuroligin 1 involved_in ISO (PMID:32324534) SynGO PMID:32324534 NCBI chr34:37,397,772...38,203,634
Ensembl chr34:37,572,629...38,203,177
JBrowse link
G NRXN1 neurexin 1 involved_in ISO (PMID:21410790) SynGO PMID:21410790 NCBI chr10:51,555,660...52,666,774
Ensembl chr10:51,558,452...52,667,569
JBrowse link
G PRICKLE1 prickle planar cell polarity protein 1 involved_in ISO (PMID:34613779) SynGO PMID:34613779 NCBI chr27:11,327,086...11,437,799
Ensembl chr27:11,426,647...11,437,303
JBrowse link
G PRICKLE2 prickle planar cell polarity protein 2 involved_in ISO (PMID:23711981), (PMID:34613779) SynGO PMID:23711981 PMID:34613779 NCBI chr20:26,810,167...27,131,864
Ensembl chr20:26,809,958...27,220,057
JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:30,137,546...30,264,221
Ensembl chr25:30,138,209...30,264,133
JBrowse link
G PTPRD protein tyrosine phosphatase receptor type D involved_in ISO PMID:29024665
(PMID:22357843)
SynGO PMID:22357843 PMID:29024665 RGD:13702141 NCBI chr11:29,100,913...31,278,495
Ensembl chr11:29,104,448...29,501,600
JBrowse link
G PTPRS protein tyrosine phosphatase receptor type S involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:54,575,853...54,672,141
Ensembl chr20:54,575,895...54,672,068
JBrowse link
G SIPA1L1 signal induced proliferation associated 1 like 1 involved_in ISO PMID:11502259 SynGO PMID:11502259 RGD:8554032 NCBI chr 8:44,916,309...45,260,197
Ensembl chr 8:44,990,495...45,258,614
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    multicellular organismal process 8083
      multicellular organism development 5174
        system development 4502
          nervous system development 2788
            synapse assembly 277
              excitatory synapse assembly 42
                negative regulation of excitatory synapse assembly 2
                positive regulation of excitatory synapse assembly 3
                postsynaptic density assembly + 32
                regulation of excitatory synapse assembly + 25
Path 2
Term Annotations click to browse term
  biological_process 17917
    cellular process 16926
      cellular component organization or biogenesis 6943
        cellular component organization 6705
          cellular component assembly 3145
            cell junction assembly 542
              synapse assembly 277
                excitatory synapse assembly 42
                  negative regulation of excitatory synapse assembly 2
                  positive regulation of excitatory synapse assembly 3
                  postsynaptic density assembly + 32
                  regulation of excitatory synapse assembly + 25
paths to the root