CASKIN1 (CASK interacting protein 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: CASKIN1 (CASK interacting protein 1) Canis lupus familiaris
Analyze
Symbol: CASKIN1
Name: CASK interacting protein 1
RGD ID: 12166812
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN regulation of postsynaptic density assembly (ortholog); signal transduction (ortholog); ASSOCIATED WITH autosomal dominant polycystic kidney disease (ortholog); developmental and epileptic encephalopathy 1 (ortholog); endometrial carcinoma (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog)
Type: protein-coding (Ensembl: pseudogene)
RefSeq Status: MODEL
Previously known as: caskin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,776,710 - 38,788,253 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,776,710 - 38,786,727 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha640,010,760 - 40,027,402 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0639,079,958 - 39,096,763 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1638,764,968 - 38,781,377 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,737,294 - 38,753,692 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,216,016 - 39,232,351 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
CASKIN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,776,710 - 38,788,253 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,776,710 - 38,786,727 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha640,010,760 - 40,027,402 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0639,079,958 - 39,096,763 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1638,764,968 - 38,781,377 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,737,294 - 38,753,692 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,216,016 - 39,232,351 (+)NCBIUU_Cfam_GSD_1.0
CASKIN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,177,180 - 2,196,605 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,177,180 - 2,196,605 (-)EnsemblGRCh38hg38GRCh38
GRCh37162,227,181 - 2,246,606 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,167,185 - 2,186,466 (-)NCBINCBI36Build 36hg18NCBI36
Build 34162,167,184 - 2,186,466NCBI
Celera162,441,604 - 2,476,669 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef162,153,438 - 2,188,429 (-)NCBIHuRef
CHM1_1162,227,157 - 2,246,403 (-)NCBICHM1_1
T2T-CHM13v2.0162,199,649 - 2,219,075 (-)NCBIT2T-CHM13v2.0
Caskin1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391724,706,871 - 24,727,883 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1724,707,575 - 24,727,645 (+)EnsemblGRCm39 Ensembl
GRCm381724,487,897 - 24,508,909 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,488,601 - 24,508,671 (+)EnsemblGRCm38mm10GRCm38
MGSCv371724,625,728 - 24,645,854 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361724,216,383 - 24,236,509 (+)NCBIMGSCv36mm8
Celera1725,004,604 - 25,024,884 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.4NCBI
Caskin1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,016,780 - 14,037,927 (+)NCBIGRCr8
mRatBN7.21013,512,684 - 13,533,380 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,513,465 - 13,533,377 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1018,259,991 - 18,279,926 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,748,836 - 17,768,771 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,248,023 - 13,267,958 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,853,107 - 13,874,254 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,854,339 - 13,874,254 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01013,670,657 - 13,691,239 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,740,593 - 13,760,485 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11013,740,569 - 13,760,484 (+)NCBI
Celera1013,193,740 - 13,213,647 (+)NCBICelera
Cytogenetic Map10q12NCBI
Caskin1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544215,030,219 - 15,092,786 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544215,075,427 - 15,092,786 (+)NCBIChiLan1.0ChiLan1.0
CASKIN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,680,201 - 2,699,622 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1166,461,014 - 6,480,427 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,035,826 - 1,055,005 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1162,278,390 - 2,293,059 (-)NCBIpanpan1.1PanPan1.1panPan2
Caskin1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,841,356 - 104,853,537 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,856,603 - 1,866,617 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,856,529 - 1,868,107 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CASKIN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,794,293 - 39,811,009 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1339,794,400 - 39,811,381 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2342,369,985 - 42,381,726 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CASKIN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.152,071,884 - 2,091,539 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl52,073,253 - 2,091,346 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606828,970,627 - 28,990,165 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Caskin1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462491362,332 - 77,819 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462491362,217 - 79,228 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CASKIN1
87 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000030864
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl638,776,710 - 38,786,727 (+)Ensembl
RefSeq Acc Id: XM_038479472   ⟹   XP_038335400
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1638,764,968 - 38,781,377 (+)NCBI
RefSeq Acc Id: XM_038479473   ⟹   XP_038335401
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1638,764,968 - 38,781,377 (+)NCBI
RefSeq Acc Id: XM_038540731   ⟹   XP_038396659
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0639,216,016 - 39,232,351 (+)NCBI
RefSeq Acc Id: XM_038549741   ⟹   XP_038405669
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha640,010,760 - 40,027,402 (+)NCBI
RefSeq Acc Id: XM_038604852   ⟹   XP_038460780
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0638,737,294 - 38,753,692 (+)NCBI
RefSeq Acc Id: XM_038669550   ⟹   XP_038525478
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0639,079,958 - 39,096,763 (+)NCBI
RefSeq Acc Id: XP_038335400   ⟸   XM_038479472
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038335401   ⟸   XM_038479473
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038460780   ⟸   XM_038604852
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038525478   ⟸   XM_038669550
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LQK0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038405669   ⟸   XM_038549741
- Peptide Label: isoform X6
- UniProtKB: A0A8C0LX61 (UniProtKB/TrEMBL),   A0A8P0PKS5 (UniProtKB/TrEMBL),   A0A8C0LQK0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038396659   ⟸   XM_038540731
- Peptide Label: isoform X5
- UniProtKB: A0A8C0LQK0 (UniProtKB/TrEMBL),   A0A8C0LX61 (UniProtKB/TrEMBL),   A0A8P0PKS5 (UniProtKB/TrEMBL)
Protein Domains
SAM   SH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000019412 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030000544 UniProtKB/TrEMBL
  ENSCAFG00845004670 ENTREZGENE
Ensembl Transcript ENSCAFT00000030864.5 UniProtKB/TrEMBL
  ENSCAFT00000100194.1 UniProtKB/TrEMBL
  ENSCAFT00000110056.1 UniProtKB/TrEMBL
  ENSCAFT00030000948.1 UniProtKB/TrEMBL
  ENSCAFT00030000979.1 UniProtKB/TrEMBL
  ENSCAFT00845008353 ENTREZGENE
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro ANKS1/Caskin UniProtKB/TrEMBL
  Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  Caskin1-CID UniProtKB/TrEMBL
  Caskin1/2_SAM_1 UniProtKB/TrEMBL
  Caskin1/2_SAM_2 UniProtKB/TrEMBL
  Caskin_C UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene CASKIN1 ENTREZGENE
PANTHER ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  PTHR24174:SF11 UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  Ank_4 UniProtKB/TrEMBL
  Caskin-Pro-rich UniProtKB/TrEMBL
  Caskin-tail UniProtKB/TrEMBL
  Caskin1-CID UniProtKB/TrEMBL
  SAM_1 UniProtKB/TrEMBL
  SH3_2 UniProtKB/TrEMBL
PRINTS ANKYRIN UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
  SAM_DOMAIN UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP SSF47769 UniProtKB/TrEMBL
  SSF48403 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
UniProt A0A8C0LQK0 ENTREZGENE
  A0A8C0LX61 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0LX82_CANLF UniProtKB/TrEMBL
  A0A8P0PKS5 ENTREZGENE
  A0A8P0TP55_CANLF UniProtKB/TrEMBL
UniProt Secondary A0A8P0PKS5 UniProtKB/TrEMBL
  A0A8P0PL48 UniProtKB/TrEMBL
VGNC ID VGNC:38730 ENTREZGENE