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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17beta-estradiol | multiple interactions | ISO | RGD:1351061 | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of CASKIN1 mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1551499 | 6480464 | Tetrachlorodibenzodioxin affects the expression of CASKIN1 mRNA | CTD | PMID:24680724 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of CASKIN1 mRNA | CTD | PMID:31881176 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of CASKIN1 mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases expression | ISO | RGD:1351061 | 6480464 | Aflatoxin B1 results in increased expression of CASKIN1 mRNA | CTD | PMID:21641981 | aflatoxin B1 | decreases methylation | ISO | RGD:1351061 | 6480464 | Aflatoxin B1 results in decreased methylation of CASKIN1 intron | CTD | PMID:30157460 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of CASKIN1 mRNA | CTD | PMID:16483693 | arsane | affects methylation | ISO | RGD:1351061 | 6480464 | Arsenic affects the methylation of CASKIN1 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | RGD:1351061 | 6480464 | Arsenic affects the methylation of CASKIN1 gene | CTD | PMID:25304211 | benzo[a]pyrene | increases methylation | ISO | RGD:1351061 | 6480464 | Benzo(a)pyrene results in increased methylation of CASKIN1 promoter | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | RGD:1351061 | 6480464 | Benzo(a)pyrene affects the methylation of CASKIN1 3' UTR, Benzo(a)pyrene affects the methylation of CASKIN1 intron | CTD | PMID:27901495, PMID:30157460 | bisphenol A | decreases expression | ISO | RGD:1551499 | 6480464 | bisphenol A results in decreased expression of CASKIN1 mRNA | CTD | PMID:26063408 | bisphenol A | multiple interactions | ISO | RGD:1351061 | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of CASKIN1 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CASKIN1 mRNA | CTD | PMID:30816183, PMID:34947998 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of CASKIN1 mRNA | CTD | PMID:25181051 | Brodifacoum | decreases expression | EXP | | 6480464 | bromfenacoum results in decreased expression of CASKIN1 protein | CTD | PMID:28903499 | cadmium atom | increases expression | ISO | RGD:1351061 | 6480464 | Cadmium results in increased expression of CASKIN1 mRNA | CTD | PMID:24376830 | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of CASKIN1 promoter | CTD | PMID:22457795 | cisplatin | multiple interactions | ISO | RGD:1351061 | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of CASKIN1 mRNA | CTD | PMID:27392435 | cobalt dichloride | decreases expression | ISO | RGD:1551499 | 6480464 | cobaltous chloride results in decreased expression of CASKIN1 mRNA | CTD | PMID:21139344 | diethylstilbestrol | decreases expression | EXP | | 6480464 | Diethylstilbestrol results in decreased expression of CASKIN1 mRNA | CTD | PMID:21658437 | dorsomorphin | multiple interactions | ISO | RGD:1351061 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CASKIN1 mRNA | CTD | PMID:27188386 | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of CASKIN1 mRNA | CTD | PMID:29391264 | ethanol | multiple interactions | ISO | RGD:1551499 | 6480464 | Ethanol affects the expression of and affects the splicing of CASKIN1 mRNA | CTD | PMID:30319688 | fulvestrant | multiple interactions | ISO | RGD:1351061 | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of CASKIN1 gene | CTD | PMID:31601247 | lead(0) | affects expression | ISO | RGD:1351061 | 6480464 | Lead affects the expression of CASKIN1 mRNA | CTD | PMID:28903495 | lead(2+) | affects expression | ISO | RGD:1351061 | 6480464 | Lead affects the expression of CASKIN1 mRNA | CTD | PMID:28903495 | methoxychlor | increases methylation | EXP | | 6480464 | Methoxychlor results in increased methylation of CASKIN1 gene | CTD | PMID:23303685 | N-methyl-4-phenylpyridinium | increases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of CASKIN1 mRNA | CTD | PMID:28801915 | N-nitrosodiethylamine | multiple interactions | ISO | RGD:1551499 | 6480464 | [Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CASKIN1 gene | CTD | PMID:23968726 | paracetamol | multiple interactions | ISO | RGD:1551499 | 6480464 | MAP3K5 protein affects the reaction [Acetaminophen results in increased expression of CASKIN1 mRNA] | CTD | PMID:18700144 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of CASKIN1 mRNA | CTD | PMID:33387578 | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of CASKIN1 mRNA | CTD | PMID:32680482 | phenylmercury acetate | decreases expression | ISO | RGD:1351061 | 6480464 | Phenylmercuric Acetate results in decreased expression of CASKIN1 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | RGD:1351061 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CASKIN1 mRNA | CTD | PMID:27188386 | phenytoin | affects expression | EXP | | 6480464 | Phenytoin affects the expression of CASKIN1 mRNA | CTD | PMID:20345932 | piperonyl butoxide | multiple interactions | ISO | RGD:1551499 | 6480464 | [Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CASKIN1 gene | CTD | PMID:23968726 | potassium dichromate | decreases expression | ISO | RGD:1551499 | 6480464 | Potassium Dichromate results in decreased expression of CASKIN1 mRNA | CTD | PMID:23608068 | resveratrol | multiple interactions | ISO | RGD:1351061 | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of CASKIN1 mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | ISO | RGD:1351061 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CASKIN1 mRNA | CTD | PMID:27188386 | sodium arsenite | decreases expression | ISO | RGD:1351061 | 6480464 | sodium arsenite results in decreased expression of CASKIN1 mRNA | CTD | PMID:34032870 | sunitinib | increases expression | ISO | RGD:1351061 | 6480464 | Sunitinib results in increased expression of CASKIN1 mRNA | CTD | PMID:31533062 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of CASKIN1 mRNA | CTD | PMID:33387578 | valproic acid | increases methylation | ISO | RGD:1351061 | 6480464 | Valproic Acid results in increased methylation of CASKIN1 gene | CTD | PMID:29154799 | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of CASKIN1 mRNA | CTD | PMID:29427782 | vorinostat | decreases expression | ISO | RGD:1351061 | 6480464 | vorinostat results in decreased expression of CASKIN1 mRNA | CTD | PMID:27188386 | |