CASKIN1 (CASK interacting protein 1) - Rat Genome Database

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Gene: CASKIN1 (CASK interacting protein 1) Chlorocebus sabaeus
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Symbol: CASKIN1
Name: CASK interacting protein 1
RGD ID: 18740093
Description: ENCODES a protein that exhibits protein domain specific binding (ortholog); INVOLVED IN signal transduction (ortholog); ASSOCIATED WITH autosomal dominant polycystic kidney disease (ortholog); developmental and epileptic encephalopathy 1 (ortholog); endometrial carcinoma (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: caskin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.152,071,884 - 2,091,539 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl52,073,253 - 2,091,346 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606828,970,627 - 28,990,165 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
glutamatergic synapse  (IEA,ISO)
postsynapse  (IEA,ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
CASKIN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.152,071,884 - 2,091,539 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl52,073,253 - 2,091,346 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606828,970,627 - 28,990,165 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CASKIN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,177,180 - 2,196,605 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,177,180 - 2,196,605 (-)EnsemblGRCh38hg38GRCh38
GRCh37162,227,181 - 2,246,606 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,167,185 - 2,186,466 (-)NCBINCBI36Build 36hg18NCBI36
Build 34162,167,184 - 2,186,466NCBI
Celera162,441,604 - 2,476,669 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef162,153,438 - 2,188,429 (-)NCBIHuRef
CHM1_1162,227,157 - 2,246,403 (-)NCBICHM1_1
T2T-CHM13v2.0162,199,649 - 2,219,075 (-)NCBIT2T-CHM13v2.0
Caskin1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391724,706,871 - 24,727,883 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1724,707,575 - 24,727,645 (+)EnsemblGRCm39 Ensembl
GRCm381724,487,897 - 24,508,909 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,488,601 - 24,508,671 (+)EnsemblGRCm38mm10GRCm38
MGSCv371724,625,728 - 24,645,854 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361724,216,383 - 24,236,509 (+)NCBIMGSCv36mm8
Celera1725,004,604 - 25,024,884 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.4NCBI
Caskin1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,016,780 - 14,037,927 (+)NCBIGRCr8
mRatBN7.21013,512,684 - 13,533,380 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,513,465 - 13,533,377 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1018,259,991 - 18,279,926 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,748,836 - 17,768,771 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,248,023 - 13,267,958 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,853,107 - 13,874,254 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,854,339 - 13,874,254 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01013,670,657 - 13,691,239 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,740,593 - 13,760,485 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11013,740,569 - 13,760,484 (+)NCBI
Celera1013,193,740 - 13,213,647 (+)NCBICelera
Cytogenetic Map10q12NCBI
Caskin1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544215,030,219 - 15,092,786 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544215,075,427 - 15,092,786 (+)NCBIChiLan1.0ChiLan1.0
CASKIN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,680,201 - 2,699,622 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1166,461,014 - 6,480,427 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,035,826 - 1,055,005 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1162,278,390 - 2,293,059 (-)NCBIpanpan1.1PanPan1.1panPan2
CASKIN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,776,710 - 38,788,253 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,776,710 - 38,786,727 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha640,010,760 - 40,027,402 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0639,079,958 - 39,096,763 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1638,764,968 - 38,781,377 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,737,294 - 38,753,692 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,216,016 - 39,232,351 (+)NCBIUU_Cfam_GSD_1.0
Caskin1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,841,356 - 104,853,537 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,856,603 - 1,866,617 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,856,529 - 1,868,107 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CASKIN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,794,293 - 39,811,009 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1339,794,400 - 39,811,381 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2342,369,985 - 42,381,726 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Caskin1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462491362,332 - 77,819 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462491362,217 - 79,228 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 18 34 34 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000008974   ⟹   ENSCSAP00000007105
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl52,073,253 - 2,091,346 (-)Ensembl
RefSeq Acc Id: XM_007982387   ⟹   XP_007980578
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.152,071,884 - 2,091,539 (-)NCBI
Vero_WHO_p1.0NW_02366606828,970,629 - 28,990,165 (+)NCBI
Sequence:
RefSeq Acc Id: XM_037989987   ⟹   XP_037845915
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606828,970,627 - 28,990,165 (+)NCBI
RefSeq Acc Id: XM_037989988   ⟹   XP_037845916
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606828,970,628 - 28,990,165 (+)NCBI
RefSeq Acc Id: XM_037989989   ⟹   XP_037845917
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606828,970,629 - 28,990,165 (+)NCBI
Protein Sequences
Protein RefSeqs XP_007980578 (Get FASTA)   NCBI Sequence Viewer  
  XP_037845915 (Get FASTA)   NCBI Sequence Viewer  
  XP_037845916 (Get FASTA)   NCBI Sequence Viewer  
  XP_037845917 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000007105
  ENSCSAP00000007105.1
RefSeq Acc Id: XP_007980578   ⟸   XM_007982387
- Peptide Label: isoform X2
- UniProtKB: A0A0D9RER6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000007105   ⟸   ENSCSAT00000008974
RefSeq Acc Id: XP_037845915   ⟸   XM_037989987
- Peptide Label: isoform X1
RefSeq Acc Id: XP_037845916   ⟸   XM_037989988
- Peptide Label: isoform X3
RefSeq Acc Id: XP_037845917   ⟸   XM_037989989
- Peptide Label: isoform X4


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000010960 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000008974.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro ANKS1/Caskin UniProtKB/TrEMBL
  Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  Caskin1-CID UniProtKB/TrEMBL
  Caskin1/2_SAM_1 UniProtKB/TrEMBL
  Caskin1/2_SAM_2 UniProtKB/TrEMBL
  Caskin1_SH3 UniProtKB/TrEMBL
  Caskin_C UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene CASKIN1 ENTREZGENE
PANTHER ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  PTHR24174:SF11 UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  Ank_4 UniProtKB/TrEMBL
  Caskin-Pro-rich UniProtKB/TrEMBL
  Caskin-tail UniProtKB/TrEMBL
  Caskin1-CID UniProtKB/TrEMBL
  SAM_1 UniProtKB/TrEMBL
  SH3_2 UniProtKB/TrEMBL
PRINTS ANKYRIN UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
  SAM_DOMAIN UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP SSF47769 UniProtKB/TrEMBL
  SSF48403 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
UniProt A0A0D9RER6 ENTREZGENE, UniProtKB/TrEMBL